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vlasy, chlupy – barva

Color of hair or fur.
MSH

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acetylcholin

A neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system.
MSH

neurotransmitter; in vertebrates is the major transmitter at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system.
CSP

A chemical made by some types of nerve cells. It is used to send messages to other cells, including other nerve cells, muscle cells, and gland cells. It is released from the nerve ending and carries signals to cells on the other side of a synapse (space between nerve cells and other cells). Acetylcholine helps control memory and the action of certain muscles. It is a type of neurotransmitter.
NCI

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protein-tyrosinkinasy

Protein kinases that catalyze the PHOSPHORYLATION of TYROSINE residues in proteins with ATP or other nucleotides as phosphate donors.
MSH

Kinases that phosphorylate protein tyrosine residues. These kinases play major roles in mitogenic signalling, and can be divided into two subfamilies: receptor tyrosine kinases, that have an extracellular ligand-binding domain, a single transmembrane domain, and an intracellular tyrosine kinase domain; and nonreceptor tyrosine kinases, which are soluble, cytoplasmic kinases. (Dictionary of Cell and Molecular Biology Online)
NCI

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Methylomonadaceae

A family of gram-negative, aerobic bacteria utilizing only one-carbon organic compounds and isolated from in soil and water.
MSH

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cholinergní vlákna

Nerve fibers liberating acetylcholine at the synapse after an impulse.
MSH

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postižení

persons with physical or mental disabilities that affect or limit their activities of daily living and that may require special accommodations.
CSP

Indication of disability.


HL7V3.0

Groups with similar restrictions or lack or ability to perform physical or mental activities in a manner or within the range considered normal for a human being.
NCI

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respirační acidóza

Respiratory retention of carbon dioxide. It may be chronic or acute.
MSH

excess retention of carbon dioxide in the body resulting from ventilatory impairment.
CSP

Acid base imbalance resulting from an accumulation of carbon dioxide secondary to hypoventilation.
NCI

A state due to excess retention of carbon dioxide in the body.
NCI

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prurigo

A name applied to several itchy skin eruptions of unknown cause. The characteristic course is the formation of a dome-shaped papule with a small transient vesicle on top, followed by crusting over or lichenification. (From Dorland, 27th ed)
MSH

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myši inbrední BALB C

Derived from albino mice stocks originally disseminated by Bagg (1913) to Snell in 1932 that has an albino coat with genotype A,b,c. The BALB/c mouse develops plasmacytomas upon injection with mineral oil, which form the mouse cell component of the mouse-human hybrid cells that are used in the production of monoclonal antibodies. This strain exhibits excellent breeding performance and a long life span which contribute to its being one of the most highly utilized of all available mouse strains.
NCI

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choroidea

The thin, highly vascular membrane covering most of the posterior of the eye between the RETINA and SCLERA.
MSH

A thin layer of tissue that is part of the middle layer of the wall of the eye, between the sclera (white outer layer of the eye) and the retina (the inner layer of nerve tissue at the back of the eye). The choriod is filled with blood vessels that bring oxygen and nutrients to the eye.
NCI

A blood vessel-containing membrane of the eye that lies between the retina and the sclera.
NCI

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zdravotní péče – koalice

Voluntary groups of people representing diverse interests in the community such as hospitals, businesses, physicians, and insurers, with the principal objective to improve health care cost effectiveness.
MSH

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akronin

A pyrano-acridone alkaloid found in RUTACEAE plants.
MSH

A natural alkaloid with an acridine structure isolated from the bark of the plant Acronychia baueri (Australian scrub ash) with antineoplastic properties. Acronycine appears to alkylate DNA and interfere with DNA replication. (NCI04)
NCI

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psilocybin

The major of two hallucinogenic components of Teonanacatl, the sacred mushroom of Mexico, the other component being psilocin. (From Merck Index, 11th ed)
MSH

A tryptamine alkaloid, isolated from various genera of fungi including the genus Psilocybe, with hallucinogenic, anxiolytic, and psychoactive activities. In vivo, psilocybine is rapidly dephosphorylated into the active compound psilocin, which activates serotonin 2A (5-HT2A) receptors in the central nervous system (CNS), mimicking the effects of serotonin.
NCI

A substance being studied in the treatment of anxiety or depression in patients with advanced cancer. It is taken from the mushroom Psilocybe mexicana. Psilocybin acts on the brain to cause hallucinations (sights, sounds, smells, tastes, or touches that a person believes to be real but are not real).
NCI

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mikrofilamenta

submicroscopic filaments composed chiefly of actin, found in the cytoplasmic matrix of most cells, often in close association with the microtubules; may play a role in cell and organelle movement and in supportive and cytoskeletal function.
CSP

The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes. [GOC:jl, ISBN:0395825172, ISBN:0815316194]
GO

A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane. [GOC:mah, ISBN:0198506732 “Oxford Dictionary of Biochemistry and Molecular Biology”, PMID:10666339]
GO

Fibers composed of MICROFILAMENT PROTEINS, which are predominately ACTIN. They are the smallest of the cytoskeletal filaments.
MSH

The finest filamentous element of the cytoskeleton, having a diameter of about 5 nm and consisting primarily of actin.
NCI

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chrom – slitiny

Specific alloys not less than 85% chromium and nickel or cobalt, with traces of either nickel or cobalt, molybdenum, and other substances. They are used in partial dentures, orthopedic implants, etc.
MSH

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zdravotnické služby

Services for the diagnosis and treatment of disease and the maintenance of health.
MSH

providing services for the diagnosis, prevention and treatment of disease and the maintenance of health.
CSP

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akupunktura

The occupational discipline of the traditional Chinese methods of ACUPUNCTURE THERAPY for treating disease by inserting needles along specific pathways or meridians.
MSH

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psychologie lékařská

A branch of psychology in which there is collaboration between psychologists and physicians in the management of medical problems. It differs from clinical psychology, which is concerned with the diagnosis and treatment of behavior disorders.
MSH

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mikrotubulární proteiny

Proteins found in the microtubules.
MSH

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chromozómy lidské, pár 14

A specific pair of GROUP D CHROMOSOMES of the human chromosome classification.
MSH

The designation for each member of the fourteenth largest human autosomal chromosome pair. Chromosome 14 spans about 105 million base pairs and represents between 3 and 3.5% of the total DNA in normal diploid cells.
NCI

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srdce – převodní systém

An impulse-conducting system composed of modified cardiac muscle, having the power of spontaneous rhythmicity and conduction more highly developed than the rest of the heart.
MSH

impulse conducting system composed of modified cardiac muscle and having the power of spontaneous rhythmicity and conduction more highly developed than the rest of the heart.
CSP

Conducting tissue of heart which consists of specialized cardiac myocyte in the myocardium.
FMA

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adenom

A benign epithelial tumor with a glandular organization.
MSH

benign epithelial tumor in which the cells form recognizable glandular structures or in which the cells are clearly derived from glandular epithelium.
CSP

A tumor that is not cancer. It starts in gland-like cells of the epithelial tissue (thin layer of tissue that covers organs, glands, and other structures within the body).
NCI

A neoplasm arising from the epithelium. It may be encapsulated or non-encapsulated but non-invasive. The neoplastic epithelial cells may or may not display cellular atypia or dysplasia. In the gastrointestinal tract, when dysplasia becomes severe it is sometimes called carcinoma in situ. Representative examples are pituitary gland adenoma, follicular adenoma of the thyroid gland, and adenomas (or adenomatous polyps) of the gastrointestinal tract.
NCI

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kyseliny pteroylpolyglutamové

Derivatives of folic acid (pteroylglutamic acid). In gamma-glutamyl linkage they are found in many tissues. They are converted to folic acid by the action of pteroylpolyglutamate hydrolase or synthesized from folic acid by the action of folate polyglutamate synthetase. Synthetic pteroylpolyglutamic acids, which are in alpha-glutamyl linkage, are active in bacterial growth assays.
MSH

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mimosin

3-Hydroxy-4-oxo-1(4H)-pyridinealanine. An antineoplastic alanine-substituted pyridine derivative isolated from Leucena glauca.
MSH

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cialit

Tissue preservative.
MSH

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vyčerpání z tepla

A clinical syndrome caused by heat stress, such as over-exertion in a hot environment or excessive exposure to sun. It is characterized by SWEATING, water (volume) depletion, salt depletion, cool clammy skin, NAUSEA, and HEADACHE.
MSH

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adenylsukcinátlyasa

An enzyme that, in the course of purine ribonucleotide biosynthesis, catalyzes the conversion of 5`-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole to 5`-phosphoribosyl-4-carboxamide-5-aminoimidazole and the conversion of adenylosuccinic acid to AMP. EC 4.3.2.2.
MSH

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pneumologie

A subspecialty of internal medicine concerned with the study of the RESPIRATORY SYSTEM. It is especially concerned with diagnosis and treatment of diseases and defects of the lungs and bronchial tree.
MSH

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mithramycin

A tricyclic pentaglycosidic antibiotic from Streptomyces strains that inhibits RNA and protein synthesis by adhering to DNA. It is used as a fluorescent dye and as an antineoplastic agent, especially in bone and testicular tumors. Plicamycin is also used to reduce hypercalcemia, especially that due to malignancies.
MSH

tricyclic pentaglycosidic antibiotic from Streptomyces strains that inhibits RNA and protein synthesis by adhering to DNA; used as a fluorescent dye and as an antineoplastic agent, especially in bone and testicular tumors; also used to reduce hypercalcemia, especially that due to malignancies.
CSP

A drug used to treat some types of testicular cancer. It is also used to treat a higher-than-normal amounts of calcium in the blood or urine. Mithracin binds to DNA and prevents cells from making RNA and proteins. It is a type of antineoplastic antibiotic.
NCI

An antibiotic isolated from the bacterium Streptomyces plicatus with antineoplastic activity. Plicamycin, also known as mithramycin, binds to the minor groove of DNA at GC-rich sites, resulting in inhibition of RNA synthesis; this agent also inhibits mRNA expression, resulting in a reduction in protein synthesis. In addition, plicamycin may inhibit bone resorption by down regulating transcription of c-src, an oncogene involved in bone metabolism and resorption. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=41738&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=41738&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C658″ NCI Thesaurus)
PDQ

An antibiotic isolated from the bacterium Streptomyces plicatus with antineoplastic activity. Plicamycin, also known as mithramycin, binds to the minor groove of DNA at GC-rich sites, resulting in inhibition of RNA synthesis; this agent also inhibits mRNA expression, resulting in a reduction in protein synthesis. In addition, plicamycin may inhibit bone resorption by down regulating transcription of c-src, an oncogene involved in bone metabolism and resorption. (NCI04)
NCI

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citráty

citric acid, its salts or esters; found in citrus fruits; an intermediate in the Krebs cycle; used as an anticoagulant for stored blood specimens.
CSP

A salt or ester of citric acid.
NCI

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