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noradrenalin

Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic.
MSH

precursor of epinephrine; widespread central and autonomic neurotransmitter, principal transmitter of most postganglionic sympathetic fibers; secreted by the adrenal medulla; used pharmacologically as a sympathomimetic.
CSP

A synthetic phenylethylamine that mimics the sympathomimetic actions of the endogenous norepinephrine. Norepinephrine acts directly on the alpha- and beta-adrenergic receptors. Clinically, norepinephrine is used as a peripheral vasoconstrictor that causes constriction of arterial and venous beds via its alpha-adrenergic action. It is also used as a potent inotropic and chronotropic stimulator of the heart mediated through its beta-1 adrenergic action.
NCI

A naturally occurring catecholamine hormone that functions as a neurotransmitter in the sympathetic nervous system. Norepinephrine directly stimulates adrenergic receptors. Stimulation of alpha-adrenergic receptors causes vasoconstriction of the radial smooth muscle of the iris, arteries, arterioles, veins, urinary bladder, and the sphincter of the gastrointestinal tract. Stimulation of beta-1 adrenergic receptors causes an increase in myocardial contractility, heart rate, automaticity, and atrioventricular (AV) conduction while stimulation of beta-2 adrenergic receptors causes bronchiolar and vascular smooth muscle dilatation.
NCI

A chemical made by some nerve cells and in the adrenal gland. It can act as both a neurotransmitter (a chemical messenger used by nerve cells) and a hormone (a chemical that travels in the blood and controls the actions of other cells or organs). Noradrenaline is released from the adrenal gland in response to stress and low blood pressure.
NCI

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imunoblastická lymfadenopatie

A disorder characterized by proliferation of arborizing small vessels, prominent immunoblastic proliferations and amorphous acidophilic interstitial material. Clinical manifestations include fever, sweats, weight loss, generalized lymphadenopathy and frequently hepatosplenomegaly.
MSH

An aggressive (fast-growing) type of T-cell non-Hodgkin lymphoma marked by enlarged lymph nodes and hypergammaglobulinemia (increased antibodies in the blood). Other symptoms may include a skin rash, fever, weight loss, or night sweats.
NCI

A mature T-cell non-Hodgkin lymphoma, characterized by systemic disease and a polymorphous infiltrate involving lymph nodes. It occurs in the middle aged and elderly, with an equal incidence in males and females. The clinical course is typically aggressive. (WHO, 2001)
NCI

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temporomandibulární kloub – nemoci

A variety of conditions affecting the anatomic and functional characteristics of the temporomandibular joint. Factors contributing to the complexity of temporomandibular diseases are its relation to dentition and mastication and the symptomatic effects in other areas which account for referred pain to the joint and the difficulties in applying traditional diagnostic procedures to temporomandibular joint pathology where tissue is rarely obtained and x-rays are often inadequate or nonspecific. Common diseases are developmental abnormalities, trauma, subluxation, luxation, arthritis, and neoplasia. (From Thoma`s Oral Pathology, 6th ed, pp577-600)
MSH

Any condition affecting the anatomic and functional characteristics of the temporomandibular joint.
NCI

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komplement C2

A component of the CLASSICAL COMPLEMENT PATHWAY. C2 is cleaved by activated COMPLEMENT C1S into COMPLEMENT C2B and COMPLEMENT C2A. C2a, the COOH-terminal fragment containing a SERINE PROTEASE, combines with COMPLEMENT C4B to form C4b2a (CLASSICAL PATHWAY C3 CONVERTASE) and subsequent C4b2a3b (CLASSICAL PATHWAY C5 CONVERTASE).
MSH

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polymery

Compounds formed by the joining of smaller, usually repeating, units linked by covalent bonds. These compounds often form large macromolecules (e.g., BIOPOLYMERS; PLASTICS).
MSH

compounds formed by the joining of smaller, usually repeating, units linked by covalent bonds; these compounds often form large macromolecules; for example, plastics, polypeptides, polysaccharides, and nucleic acids.
CSP

A molecule made up of a linked series of repeated monomers.
NCI

A molecule made up of small identical molecules called monomers. The monomers are joined together in a repeating pattern.
NCI

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imunologický capping

An energy dependent process following the crosslinking of B CELL ANTIGEN RECEPTORS by multivalent ligands (bivalent anti-antibodies, LECTINS or ANTIGENS), on the B-cell surface. The crosslinked ligand-antigen receptor complexes collect in patches which flow to and aggregate at one pole of the cell to form a large mass – the cap. The caps may then be endocytosed or shed into the environment.
MSH

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syndrom rezistence na androgeny

A disorder of sexual development transmitted as an X-linked recessive trait. These patients have a karyotype of 46,XY with end-organ resistance to androgen due to mutations in the androgen receptor (RECEPTORS, ANDROGEN) gene. Severity of the defect in receptor quantity or quality correlates with their phenotypes. In these genetic males, the phenotypic spectrum ranges from those with normal female external genitalia, through those with genital ambiguity as in Reifenstein Syndrome, to that of a normal male with INFERTILITY.
MSH

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Complication

In medicine, a medical problem that occurs during a disease, or after a procedure or treatment. The complication may be caused by the disease, procedure, or treatment or may be unrelated to them.
NCI

Any disease or disorder that occurs during the course of (or because of) another disease.
NCI

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polythiazid

A thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p826)
MSH

A sulfonamide derivative and a synthetic thiazide with diuretic, antihypertensive and anti-urolithic properties. By blocking the Na/Cl transporter, polythiazide inhibits reabsorption of sodium and chloride in the proximal and distal convoluted tubule of the kidney, resulting in increased excretion of water and electrolytes (sodium, potassium, chloride, magnesium, and bicarbonate) and subsequent reversal of hypertension. In addition, this agent exerts its anti-urolithic effect by decreasing calcium and uric acid excretion.
NCI

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Motieven

A benefit, consideration, or positive motivational influence, financial or otherwise, given to induce a specific action.
NCI

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Tetrahymena

genus in the order Hymenostomatida; ciliate protozoa commonly used in genetic, cytological and other research.
CSP

A genus of ciliate protozoa commonly used in genetic, cytological, and other research.
MSH

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konduktometrie

Determination of the quantity of a material present in a mixture by measurement of its effect on the electrical conductivity of the mixture. (Webster, 3d ed)
MSH

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portokavální zkrat chirurgický

Surgical portasystemic shunt between the portal vein and inferior vena cava.
MSH

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individualita

Those psychological characteristics which differentiate individuals from one another.
MSH

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thenoyltrifluoraceton

Chelating agent and inhibitor of cellular respiration.
MSH

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konzervovaná sekvence

A sequence of amino acids in a polypeptide or of nucleotides in DNA or RNA that is similar across multiple species. A known set of conserved sequences is represented by a CONSENSUS SEQUENCE. AMINO ACID MOTIFS are often composed of conserved sequences.
MSH

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jodid draselný

An inorganic compound that is used as a source of iodine in thyrotoxic crisis and in the preparation of thyrotoxic patients for thyroidectomy. (From Dorland, 27th ed)
MSH

A metal halide composed of potassium and iodide with thyroid protecting and expectorant properties. Potassium iodide can block absorption of radioactive iodine by the thyroid gland through flooding the thyroid with non-radioactive iodine and preventing intake of radioactive molecules, thereby protecting the thyroid from cancer causing radiation. In addition, this agent acts as an expectorant by increasing secretion of respiratory fluids resulting in decreased mucus viscosity.
NCI

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novorozenec malý vzhledem ke gestačnímu věku

An infant having a birth weight lower than expected for its gestational age.
MSH

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thiamintrifosfatasa

An enzyme present in nerve tissue. It catalyzes reversibly the formation of thiamine diphosphate and orthophosphate from thiamine triphosphate. EC 3.6.1.28.
MSH

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antikoncepční látky orální hormonální

Oral contraceptives which owe their effectiveness to hormonal preparations.
MSH

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preexcitace – typ Mahaimův

A form of ventricular pre-excitation characterized by a normal PR interval and a long QRS interval with an initial slow deflection (delta wave). In this syndrome, the atrial impulse travel to the ventricle via the MAHAIM FIBERS which connect ATRIOVENTRICULAR NODE directly to the right ventricle wall (NODOVENTRICULAR ACCESSORY PATHWAY) or to the RIGHT BUNDLE BRANCH OF HIS (nodofascicular accessory pathway).
MSH

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infúzní pumpy implantabilní

Implanted fluid propulsion systems with self-contained power source for providing long-term controlled-rate delivery of drugs such as chemotherapeutic agents or analgesics. Delivery rate may be externally controlled or osmotically or peristatically controlled with the aid of transcutaneous monitoring.
MSH

A small device installed under the skin to administer a steady dose of drugs.
NCI

A small device installed under the skin to provide long-term controlled-rate delivery of drugs such as chemotherapeutic agents or analgesics. Delivery rate may be externally controlled or osmotically or peristaltically controlled with the aid of transcutaneous monitoring.
NCI

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thioredoxin-disulfidreduktasa

A FLAVOPROTEIN enzyme that catalyzes the oxidation of THIOREDOXINS to thioredoxin disulfide in the presence of NADP+. It was formerly listed as EC 1.6.4.5
MSH

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koproporfyriny

Porphyrins with four methyl and four propionic acid side chains attached to the pyrrole rings. Elevated levels of Coproporphyrin III in the urine and feces are major findings in patients with HEREDITARY COPROPORPHYRIA.
MSH

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těhotenství – třetí trimestr

The last third of a human PREGNANCY, from the beginning of the 29th through the 42nd completed week (197 to 294 days) of gestation.
MSH

The period of gestation that ranges from the 28th week of pregnancy until delivery.
NCI

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inosindifosfát

An inosine nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety.
MSH

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threonin-tRNA-ligasa

An enzyme that activates threonine with its specific transfer RNA. EC 6.1.1.3.
MSH

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corpora allata

Paired or fused ganglion-like bodies in the head of insects. The bodies secrete hormones important in the regulation of metamorphosis and the development of some adult tissues.
MSH

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prenatální expozice – zpožděný efekt

The consequences of exposing the FETUS in utero to certain factors, such as NUTRITION PHYSIOLOGICAL PHENOMENA; PHYSIOLOGICAL STRESS; DRUGS; RADIATION; and other physical or chemical factors. These consequences are observed later in the offspring after BIRTH.
MSH

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anémie sideroblastická

Anemia characterized by the presence of erythroblasts containing excessive deposits of iron in the marrow.
MSH

acquired or hereditary anemia marked by sideroblasts: bone marrow cells with large mitochondrial deposits of insoluble iron due to defective heme synthesis, leading to ineffective erythropoiesis.
CSP

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