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L-serindehydratasa

A PYRIDOXAL-phosphate containing enzyme that catalyzes the dehydration and deamination of L-serine to form pyruvate. This enzyme was formerly listed as EC 4.2.1.13.
MSH

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molybdoferredoxin

A non-heme iron-sulfur protein isolated from Clostridium pasteurianum and other bacteria. It is a component of NITROGENASE, which is active in nitrogen fixation, and consists of two subunits with molecular weights of 59.5 kDa and 50.7 kDa, respectively.
MSH

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přeučení

Learning in which practice proceeds beyond the point where the act can just be performed with the required degree of excellence.
MSH

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hemoglobin srpkovitý

An abnormal hemoglobin resulting from the substitution of valine for glutamic acid at position 6 of the beta chain of the globin moiety. The heterozygous state results in sickle cell trait, the homozygous in sickle cell anemia.
MSH

abnormal hemoglobin caused by a point mutation in the beta chains, found in sickle cell anemia.
CSP

An abnormal hemoglobin assay is a device consisting of the reagents, apparatus, instrumentation, and controls necessary to isolate and identify abnormal genetically determined hemoglobin types.
SPN

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kryptokokóza

infection with a fungus of the species Cryptococcus neoformans.
CSP

An acute or chronic, localized or disseminated infection by Cryptococcus neoformans. Sites of involvement include the lungs, central nervous system and meninges, skin, and visceral organs.–2004
NCI

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antropologie kulturní

It is the study of social phenomena which characterize the learned, shared, and transmitted social activities of particular ethnic groups with focus on the causes, consequences, and complexities of human social and cultural variability.
MSH

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setariáza

Infection with nematodes of the genus Setaria. This condition is usually seen in cattle and equines and is of little pathogenic significance, although migration of the worm to the eye may lead to blindness.
MSH

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nálada

A relatively temporary state of feeling.
NCI

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oximy

Compounds that contain the radical R2C=N.OH derived from condensation of ALDEHYDES or KETONES with HYDROXYLAMINE. Members of this group are CHOLINESTERASE REACTIVATORS.
MSH

compounds containing the group C=NOH.
CSP

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HEMORROIDEAK

Swollen veins in the lower part of the RECTUM or ANUS. Hemorrhoids can be inside the anus (internal), under the skin around the anus (external), or protruding from inside to outside of the anus. People with hemorrhoids may or may not exhibit symptoms which include bleeding, itching, and pain.
MSH

An enlarged or swollen blood vessel, usually located near the anus or the rectum.
NCI

Hemorrhoids are swollen, inflamed veins around the anus or lower rectum. They are either inside the anus or under the skin around the anus. They often result from straining to have a bowel movement. Other factors include pregnancy, aging and chronic constipation or diarrhea.

Hemorrhoids are very common in both men and women. About half of all people have hemorrhoids by age 50. The most common symptom of hemorrhoids inside the anus is bright red blood covering the stool, on toilet paper or in the toilet bowl. Symptoms usually go away within a few days.

If you have rectal bleeding you should see a doctor. You need to make sure bleeding is not from a more serious condition such as colorectal or anal cancer. Treatment may include warm baths and a cream or other medicine. If you have large hemorrhoids, you may need surgery and other treatments.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases


MEDLINEPLUS

A disorder characterized by the presence of dilated veins in the rectum and surrounding area.
NCI

Dilated veins in the rectum and anal area.
NCI

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kyanamid

A cyanide compound which has been used as a fertilizer, defoliant and in many manufacturing processes. It often occurs as the calcium salt, sometimes also referred to as cyanamide. The citrated calcium salt is used in the treatment of alcoholism.
MSH

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protilátky – afinita

A measure of the binding strength between antibody and a simple hapten or antigen determinant. It depends on the closeness of stereochemical fit between antibody combining sites and antigen determinants, on the size of the area of contact between them, and on the distribution of charged and hydrophobic groups. It includes the concept of “avidity,” which refers to the strength of the antigen-antibody bond after formation of reversible complexes.
MSH

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sexuálně přenosné nemoci bakteriální

Bacterial diseases transmitted or propagated by sexual conduct.
MSH

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pohyb – percepce

The real or apparent movement of objects through the visual field.
MSH

sensory interpretation of the movement of objects or persons.
CSP

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ozón

An unstable triatomic form of oxygen, O3, that exists in the atmosphere in varying proportions. It is produced continuously in the outer layers of the atmosphere by the action of solar UV-radiation on the oxygen of the air.
MSH

triatomic form of oxygen, O3; a pungent, unstable blue gas that in the upper atmosphere forms a protective layer against excess ultraviolet radiation and is an ingredient of photochemical smog in the lower atmosphere; used in the purification of drinking water and as an oxidizing agent.
CSP

Ozone is a gas. It can be good or bad, depending on where it is. “Good” ozone occurs naturally about 10 to 30 miles above the Earth`s surface. It shields us from the sun`s ultraviolet rays. Part of the good ozone layer is gone – destroyed by man-made chemicals. Without enough good ozone, people may get too much ultraviolet radiation. This may increase the risk of skin cancer, cataracts and immune system problems.

“Bad” ozone is at ground level. It forms when pollutants from cars, factories and other sources react chemically with sunlight. It is the main ingredient in smog. It is usually worst in the summer. Breathing bad ozone can be harmful, causing coughing, throat irritation, worsening of asthma, bronchitis and emphysema, and even permanent lung damage, if you are regularly exposed to it.

Environmental Protection Agency


MEDLINEPLUS

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virus hepatitidy B

A virus that causes hepatitis (inflammation of the liver). It is carried and passed to others through blood or sexual contact. Also, infants born to infected mothers may become infected with the virus.
NCI

The type species of the genus ORTHOHEPADNAVIRUS which causes human HEPATITIS B and is also apparently a causal agent in human HEPATOCELLULAR CARCINOMA. The Dane particle is an intact hepatitis virion, named after its discoverer. Non-infectious spherical and tubular particles are also seen in the serum.
MSH

Hepatitis B Virus (HBV) is the prototype of the Hepadnavirus Family. Included in the family are the Woodchuck Hepatitis Virus (WHV) and the Duck Hepatitis B Virus (DHBV) which provide animal models of infection. The HBV genome is a partially double stranded circular DNA. A viral reverse transcriptase is bound to the 5` extremity of the long strand. (from http://www.genetique.uvsq.fr/RC/virologie/hepatiteB_2_uk.html)
NCI

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cyklofosfamid

Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the LIVER to form the active aldophosphamide. It has been used in the treatment of LYMPHOMA and LEUKEMIA. Its side effect, ALOPECIA, has been used for defleecing sheep. Cyclophosphamide may also cause sterility, birth defects, mutations, and cancer.
MSH

precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent; used in the treatment of lymphomas, leukemias and other cancers, and as an immunosupressive agent to prevent transplant rejection; its side effect, alopecia, has been used for defleecing sheep; may also cause sterility, birth defects, mutations, and cancer.
CSP

A drug that is used to treat many types of cancer and is being studied in the treatment of other types of cancer. It is also used to treat some types of kidney disease in children. Cyclophosphamide attaches to DNA in cells and may kill cancer cells. It is a type of alkylating agent.
NCI

A synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities. In the liver, cyclophosphamide is converted to the active metabolites aldophosphamide and phosphoramide mustard, which bind to DNA, thereby inhibiting DNA replication and initiating cell death. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39748&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39748&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C405″ NCI Thesaurus)
PDQ

A synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities. In the liver, cyclophosphamide is converted to the active metabolites aldophosphamide and phosphoramide mustard, which bind to DNA, thereby inhibiting DNA replication and initiating cell death.
NCI

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antigeny diferenciační

Antigens expressed primarily on the membranes of living cells during sequential stages of maturation and differentiation. As immunologic markers they have high organ and tissue specificity and are useful as probes in studies of normal cell development as well as neoplastic transformation.
MSH

antigens normally only seen at particular phases of differentiation of a cell type.
CSP

Antigens expressed primarily on the membranes of living cells during sequential stages of maturation and differentiation. As immunologic markers they have high organ and tissue specificity and are useful as probes in studies of normal cell development as well as neoplastic transformation. (MeSH)
NCI

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rameno – luxace

Displacement of the HUMERUS from the SCAPULA.
MSH

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Mosambik

A republic in southern Africa, south of TANZANIA, east of ZAMBIA and ZIMBABWE, bordered on the west by the Indian Ocean. Its capital is Maputo. It was formerly called Portuguese East Africa.
MSH

A country in Southern Africa, bordering the Mozambique Channel, between South Africa and Tanzania. (NCI)
NCI

A country in Southern Africa, bordering the Mozambique Channel, between South Africa and Tanzania. (CIA World Factbook 2002)
NCI

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patro – nádory

Tumors or cancer of the PALATE, including those of the hard palate, soft palate and UVULA.
MSH

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hernie brániční traumatická

The type of DIAPHRAGMATIC HERNIA caused by TRAUMA or injury, usually to the ABDOMEN.
MSH

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kaspasy

A family of intracellular CYSTEINE ENDOPEPTIDASES that play a role in regulating INFLAMMATION and APOPTOSIS. They specifically cleave peptides at a CYSTEINE amino acid that follows an ASPARTIC ACID residue. Caspases are activated by proteolytic cleavage of a precursor form to yield large and small subunits that form the enzyme. Since the cleavage site within precursors matches the specificity of caspases, sequential activation of precursors by activated caspases can occur.
MSH

The caspases are a family of proteases responsible for carrying out the cell death process. In a living cell, these proteases are kept inactive by proteins on the mitochondrial cell surface from the BcL-2 family. When a cell is exposed to cell death signals such as ischemia, chemotherapy or radiation, BcL-2 function is blocked and caspase activators initiate the cell death cascade.
NCI

Caspases are a family of intracellular cysteine proteinases involved in inflammation and apoptosis. These enzymes appear to be involved in the initial signaling events, as well as the downstream proteolytic cleavages, that result in apoptotic cell death. They are specific for aspartic acid at the P1 position and are divided into two classes based on the lengths of their N-terminal pro-domains. Caspases-1, -2, -4, -5, -8, and -10 have long pro-domains; caspases-3, -6, -7, and -9 have short pro-domains. (from Science 1998. 281:1312 and Br Med Bull 1997. 53:478)
NCI

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antitumorózní látky

Substances that inhibit or prevent the proliferation of NEOPLASMS.
MSH

agent that inhibits or prevents the development or proliferation of neoplasms.
CSP

A drug used to treat cancer.
NCI

NOTE: Includes hormones (AN500) which are exclusively used as antineoplastics (e.g.,tamoxifen). Excludes other hormones (HS000).
NDFRT

A substance that inhibits the maturation, growth or spread of tumor cells.
NCI

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příznaky a symptomy ústrojí dýchacího

Respiratory system manifestations of diseases of the respiratory tract or of other organs.
MSH

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osobnost – poruchy mnohočetné

A dissociative disorder in which the individual adopts two or more distinct personalities. Each personality is a fully integrated and complex unit with memories, behavior patterns and social friendships. Transition from one personality to another is sudden.
MSH

A disorder characterized by the presence of two or more identities with distinct patterns of perception and personality which recurrently take control of the person`s behavior; this is accompanied by a retrospective gap in memory of important personal information that far exceeds ordinary forgetfulness. The changes in identity are not due to substance use or to a general medical condition.
NCI

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pankreas – píštěl

Abnormal passage communicating with the PANCREAS.
MSH

An abnormal communication between the pancreas and another organ or cavity.
NCI

A disorder characterized by an abnormal communication between the pancreas and another organ or anatomic site.
NCI

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Heterophyidae

A family of intestinal flukes of the class Trematoda which occurs in animals and man. Some of the genera are Heterophyes, Metagonimus, Cryptocotyle, Stellantchasmus, and Euryhelmis.
MSH

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cytochemie

Branch of histochemistry associated with the localization of cellular components by specific staining methods, as for example the localization of acid phosphatases by the Gomori method.
NCI

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anus

The lower opening of the digestive tract, lying in the cleft between the buttocks, through which fecal matter is extruded.
NCI

The opening of the rectum to the outside of the body.
NCI

The lower opening of the digestive tract, lying in the cleft between the buttocks, through which fecal matter is extruded. (NCI)
NCI

The external outlet of the GASTROINTESTINAL TRACT.
MSH

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