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specializační komise

Organizations which certify physicians and dentists as specialists in various fields of medical and dental practice.
MSH

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chování při pití

Behaviors associated with the ingesting of water and other liquids; includes rhythmic patterns of drinking (time intervals – onset and duration), frequency and satiety.
MSH

The specific actions or reactions of an organism relating to the intake of liquids, especially water. [GOC:curators]
GO

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polyester pentosanu kyseliny sírové

A sulfated pentosyl polysaccharide with heparin-like properties.
MSH

anhydride or polymerized form of any pentose.
CSP

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virus lymfocytární choriomeningitidy

The type species of ARENAVIRUS, part of the Old World Arenaviruses (ARENAVIRUSES, OLD WORLD), producing a silent infection in house and laboratory mice. In humans, infection with LCMV can be inapparent, or can present with an influenza-like illness, a benign aseptic meningitis, or a severe meningoencephalomyelitis. The virus can also infect monkeys, dogs, field mice, guinea pigs, and hamsters, the latter an epidemiologically important host.
MSH

type species of Arenavirus, part of the Old World Arenaviruses etiologic agent of lymphocytic choriomeningitis; occurs naturally in mice, dogs and monkeys.
CSP

A species of single-stranded, negative-sense RNA viruses in the genus arenavirus and family arenaviridae. It is spread by rodents and causes meningitis and encephalitis.
NCI

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Blastomyces dermatitidis

etiologic agent of North American blastomycosis.
CSP

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gamma1-MSH

The 11-residue peptide that is fully amidated.
MSH

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spermie – aglutinace

Agglutination of spermatozoa by antibodies or autoantibodies.
MSH

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léky – rezistence

Diminished or failed response of an organism, disease or tissue to the intended effectiveness of a chemical or drug. It should be differentiated from DRUG TOLERANCE which is the progressive diminution of the susceptibility of a human or animal to the effects of a drug, as a result of continued administration.
MSH

tendency of biological systems (organisms, cells, or cell-free systems) to fail to respond as expected to drug treatment or exposure; may be due to specific enzymes, transporters, or receptors which block drug action.
CSP

OBSOLETE (was not defined before being made obsolete). [GOC:go_curators]
GO

Mechanisms, functions, activities, or processes exhibited by tumors or pathogens to withstand previously toxic drugs.
NCI

The failure of cancer cells, viruses, or bacteria to respond to a drug used to kill or weaken them. The cells, viruses, or bacteria may be resistant to the drug at the beginning of treatment, or may become resistant after being exposed to the drug.
NCI

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Peptococcaceae

A family of bacteria found in the mouth and intestinal and respiratory tracts of man and other animals as well as in the human female urogenital tract. Its organisms are also found in soil and on cereal grains.
MSH

A taxonomic family of bacterium in the phylum Firmicutes that includes the genera Dehalobacter, Peptococcus and Thermincola, among others.
NCI

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Macaca

large genus of Old World monkeys (family Cercopithecidae) that includes the macaque and rhesus monkeys, and the Barbary apes; Macaca mulatta, the rhesus monkey, is used as a research animal.
CSP

A genus of the subfamily CERCOPITHECINAE, family CERCOPITHECIDAE, consisting of 16 species inhabiting forests of Africa, Asia, and the islands of Borneo, Philippines, and Celebes.
MSH

Any of several species of short-tailed monkeys of the genus Macacus.
NCI

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krevní glukosa

Glucose in blood.
MSH

levels of glucose found in the blood.
CSP

Glucose (a type of sugar) found in the blood.
NCI

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žaludek – píštěl

Abnormal passage communicating with the STOMACH.
MSH

abnormal passage communicating with the stomach; often applied to an artificially created opening through the abdominal wall into the stomach (gastrostoma).
CSP

An abnormal communication between the stomach and another organ or anatomic site.
NCI

A disorder characterized by an abnormal communication between the stomach and another organ or anatomic site.
NCI

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sféroplasty

Cells, usually bacteria or yeast, which have partially lost their cell wall, lost their characteristic shape and become round.
MSH

Cells, usually bacteria or yeast, which have partially lost their cell wall, lost their characteristic shape and become round. (MeSH)
NCI

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Papilla duodeni, minor

The minor duodenal papilla (when present) connects the accessory pancreatic duct to the DUODENUM.
MSH

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perikarditida

Inflammation of the PERICARDIUM from various origins, such as infection, neoplasm, autoimmune process, injuries, or drug-induced. Pericarditis usually leads to PERICARDIAL EFFUSION, or CONSTRICTIVE PERICARDITIS.
MSH

A disorder characterized by irritation to the layers of the pericardium (the protective sac around the heart).
NCI

An inflammatory process affecting the pericardium.
NCI

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magnetická rezonanční tomografie

Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques.
MSH

non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images; concept includes proton spin tomographic techniques.
CSP

A procedure in which radio waves and a powerful magnet linked to a computer are used to create detailed pictures of areas inside the body. These pictures can show the difference between normal and diseased tissue. NMRI makes better images of organs and soft tissue than other scanning techniques, such as computed tomography (CT) or x-ray. NMRI is especially useful for imaging the brain, the spine, the soft tissue of joints, and the inside of bones.
NCI

Magnetic resonance imaging (MRI) uses a large magnet and radio waves to look at organs and structures inside your body. Health care professionals use MRI scans to diagnose a variety of conditions, from torn ligaments to tumors. MRIs are very useful for examining the brain and spinal cord.

During the scan, you lie on a table that slides inside a tunnel-shaped machine. Doing the scan can take a long time, and you must stay still. The scan is painless. The MRI machine makes a lot of noise. The technician may offer you earplugs.

Before you get a scan, tell your doctor if you

  • Are pregnant
  • Have pieces of metal in your body. You might have metal in your body if you have a shrapnel or bullet injury or if you are a welder
  • Have electronic devices in your body, such as a cardiac pacemaker


MEDLINEPLUS

Imaging that uses radiofrequency waves and a strong magnetic field rather than x-rays to provide amazingly clear and detailed pictures of internal organs and tissues. The technique is valuable for the diagnosis of many pathologic conditions, including cancer, heart and vascular disease, stroke, and joint and musculoskeletal disorders.
NCI

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hematoretinální bariéra

A specialized transport barrier, in the EYE, formed by the retinal pigment EPITHELIUM, and the ENDOTHELIUM of the BLOOD VESSELS of the RETINA. TIGHT JUNCTIONS joining adjacent cells keep the barrier between cells continuous.
MSH

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Gaucherova nemoc

An autosomal recessive disorder caused by a deficiency of acid beta-glucosidase (GLUCOSYLCERAMIDASE) leading to intralysosomal accumulation of glycosylceramide mainly in cells of the MONONUCLEAR PHAGOCYTE SYSTEM. The characteristic Gaucher cells, glycosphingolipid-filled HISTIOCYTES, displace normal cells in BONE MARROW and visceral organs causing skeletal deterioration, hepatosplenomegaly, and organ dysfunction. There are several subtypes based on the presence and severity of neurological involvement.
MSH

autosomal recessive disorder caused by deficiency of the enzyme glucocerebrosidase featuring the pathological storage of glycosylceramide in mononuclear phagocytes; the most common subtype is the non-neuronopathic form, a slowly progressive condition characterized by hepatosplenomegaly and skeletal deformities; the neuronopathic forms are divided into infantile and juvenile forms; the infantile form presents at 4-5 months of age with anemia, loss of cognitive gains, neck retraction, dysphagia, and hepatosplenomegaly; the juvenile form features a slowly progressive loss of intellect, hepatosplenomegaly, ataxia, myoclonic seizures, and spasticity; the neuronopathic forms are characterized by neuronal loss with neuronophagia, and accumulation of glucocerebroside in neurons.
CSP

An inherited lysosomal storage disease caused by deficiency of the enzyme glucocerebrosidase. It results in the accumulation of a fatty substance called glucocerebroside in mononuclear cells in the bone marrow, liver, spleen, brain, and kidneys. Signs and symptoms include hepatomegaly, splenomegaly, neurologic disorders, lymphadenopathy, skeletal disorders, anemia and thrombocytopenia.
NCI

Gaucher`s disease is a rare, inherited disorder that causes too much of a substance called glucocerebroside to build up in your spleen, liver, lungs, bones and sometimes in your brain. The buildup prevents these organs from working properly.

There are three types:

  • Type 1, the most common form, causes liver and spleen enlargement, bone pain and broken bones, and, sometimes, lung and kidney problems. It does not involve the brain. It can occur at any age.
  • Type 2, which causes severe brain damage, appears in infants. Most children who have it die by age 2.
  • In type 3, there may be liver and spleen enlargement, and signs of brain involvement appear gradually.

Gaucher`s disease has no cure. Treatment options for types 1 and 3 include medicine and enzyme replacement therapy, which is usually very effective. There is no good treatment for the brain damage of type 2.

NIH: National Institute of Neurological Disorders and Stroke


MEDLINEPLUS

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lamina spiralis ossea

The bony plate which extends outwards from the modiolus into the spiral canal of the cochlea, forming part of the structure that divides the upper SCALA VESTIBULI and the lower SCALA TYMPANI.
MSH

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HILEROKOAREN MINA

Painful menstruation.
MSH

A disorder characterized by abnormally painful abdominal cramps during menses.
NCI

Abnormally painful abdominal cramps during menstruation.
NCI

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periferní nervy

Subdivision of peripheral nervous system which is a tree whose trunk is a branch of a somatic nerve plexus (cervical, brachial or lumbosacral); it has shared parts with the somatic nerves that contribute to its parent plexus. Examples: phrenic nerve, radial nerve, ilioinguinal nerve, sciatic nerve.
UWDA

The nerves outside of the brain and spinal cord, including the autonomic, cranial, and spinal nerves. Peripheral nerves contain non-neuronal cells and connective tissue as well as axons. The connective tissue layers include, from the outside to the inside, the epineurium, the perineurium, and the endoneurium.
MSH

Neural tree (organ) which is directly continuous with the neuraxis. Examples: phrenic nerve, radial nerve, ilioinguinal nerve, sciatic nerve.
FMA

Any nerve outside the brain or spinal cord that connects with peripheral receptors or effectors. (NCI)
NCI

Any nerve outside the brain or spinal cord that connects with peripheral receptors or effectors.
NCI

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maligní hypertermie

Rapid and excessive rise of temperature accompanied by muscular rigidity following general anesthesia.
MSH

usually inherited reaction to general anesthesia manifested as a sudden, rapid rise in temperature, hypermetabolism, and skeletal muscle rigidity; mutation is in the calcium release channel of skeletal muscle sarcoplasmic reticulum.
CSP

A rare disorder characterized by rapid rise of the body temperature, accompanied by rhabdomyolysis and, if untreated, by collapse and death. It occurs in susceptible individuals who receive certain drugs for general anesthesia, gas anesthetics, or succinylcholine. It may be inherited in an autosomal dominant pattern.
NCI

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bombesin

A tetradecapeptide originally obtained from the skins of toads Bombina bombina and B. variegata. It is also an endogenous neurotransmitter in many animals including mammals. Bombesin affects vascular and other smooth muscle, gastric secretion, and renal circulation and function.
MSH

tetradecapeptide; endogenous neurotransmitter in many animals including mammals; affects vascular and other smooth muscle, gastric secretion, and renal circulation and function; originally obtained from the skins of toads of the genus Bombina.
CSP

A peptide (small protein) found in the brain, gastrointestinal tract, and lungs. It causes the release of certain hormones and enzymes. It also causes smooth muscles to contract. Bombesin is found at high levels on small cell lung cancer cells and on other types of cancer cells. It is a type of neuropeptide and a type of hormone.
NCI

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genová přestavba

The ordered rearrangement of gene regions by DNA recombination such as that which occurs normally during development.
MSH

covalent DNA changes in cells during normal differentiation resulting in new sequences, expression, or gene products; mechanism of binding site diversification for antibodies, certain receptors, and possibly other proteins.
CSP

Any DNA sequence rearrangement that results in the creation of a novel protein-coding capacity. Within certain genes, gene rearrangement is a normal part of development, facilitating the affinity maturation of B and T lymphocytes as well as class switching of immunoglobulins.
NCI

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spondylolýza

Deficient development or degeneration of a portion of the VERTEBRA, usually in the pars interarticularis (the bone bridge between the superior and inferior facet joints of the LUMBAR VERTEBRAE) leading to SPONDYLOLISTHESIS.
MSH

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ekdyson

A steroid hormone that regulates the processes of MOLTING or ecdysis in insects.
MSH

steroid hormone that regulates the processes of molting or ecdysis in insects.
CSP

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NORTASUNAREN NAHASTEA

A major deviation from normal patterns of behavior.
MSH

when normal personality traits become inflexible and maladaptive, causing subjective distress or impaired social functioning, they can be considered disorders.
CSP

Personality disorders are long-term patterns of thoughts and behaviors that cause serious problems with relationships and work. People with personality disorders have difficulty dealing with everyday stresses and problems. They often have stormy relationships with other people. The exact cause of personality disorders is unknown. However, genes and childhood experiences may play a role.

Symptoms vary widely depending on the specific type of personality disorder. Treatment usually includes talk therapy and sometimes medicine.


MEDLINEPLUS

A diverse category of psychiatric disorders characterized by behavior that deviates markedly from the expectations of the individual`s culture; this pattern of deviation is pervasive and inflexible and is stable over time. The behavioral pattern negatively interferes with relationships and work.
NCI

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mandibula – poranění

Injuries to the lower jaw bone.
MSH

Your jaw is a set of bones that holds your teeth. It consists of two main parts. The upper part is the maxilla. It doesn`t move. The moveable lower part is called the mandible. You move it when you talk or chew. The two halves of the mandible meet at your chin. The joint where the mandible meets your skull is the temporomandibular joint.

Jaw problems include

Treatment of jaw problems depends on the cause.


MEDLINEPLUS

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recenze

Works consisting of critical analyses of books or other monographic works.
MSH

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geny nef

DNA sequences that form the coding region for a protein that down-regulates the expression of human immunodeficiency virus (HIV). nef is short for negative factor.
MSH

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