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Onchocerca

A genus of parasitic nematodes whose organisms live and breed in skin and subcutaneous tissues. Onchocercal microfilariae may also be found in the urine, blood, or sputum.
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kalsequestrin

Acidic protein found in SARCOPLASMIC RETICULUM that binds calcium to the extent of 700-900 nmoles/mg. It plays the role of sequestering calcium transported to the interior of the intracellular vesicle.
MSH

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Leydigovy buňky

Steroid-producing cells in the interstitial tissue of the TESTIS. They are under the regulation of PITUITARY HORMONES; LUTEINIZING HORMONE; or interstitial cell-stimulating hormone. TESTOSTERONE is the major androgen (ANDROGENS) produced.
MSH

epithelioid cells constituting the endocrine tissue of the testis, which elaborate androgens, chiefly testosterone.
CSP

Cells in the interstitial tissue of the testis that are believed to furnish the internal secretion of that gland. (MeSH)
NCI

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sarkoidóza plicní

Sarcoidosis affecting predominantly the lungs, the site most frequently involved and most commonly causing morbidity and mortality in sarcoidosis. Pulmonary sarcoidosis is characterized by sharply circumscribed granulomas in the alveolar, bronchial, and vascular walls, composed of tightly packed cells derived from the mononuclear phagocyte system. The clinical symptoms when present are dyspnea upon exertion, nonproductive cough, and wheezing. (Cecil Textbook of Medicine, 19th ed, p431)
MSH

Sarcoidosis affecting the lung parenchyma. It is characterized by the presence of non-necrotizing granulomas in the lung tissues. It is manifested with dyspnea, cough, fever, night sweats, fatigue, and weight loss.
NCI

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flurazepam

A benzodiazepine derivative used mainly as a hypnotic.
MSH

benzodiazepine derivative used mainly as a sedative and hypnotic in the treatment of insomnia.
CSP

A member of the benzodiazepines and a long-acting depressor of the central nervous system (CNS) with sedative and hypnotic effects. Flurazepam binds to a specific site on the benzodiazepine-gamma-aminobutyric acid (GABA)-A-chloride ionophore receptor complex located on the neuronal membrane. Binding causes an allosteric modification of the receptor thereby enhancing the affinity of GABA to the receptor leading to an increase in the frequency of chloride-channel opening events, which leads to an increase in chloride ion conductance, neuronal hyperpolarization, inhibition of the action potential, and a decrease in neuronal excitability. By modulating binding of the GABA inhibitory neurotransmitter to GABA-A receptors in the ascending reticular activating system, flurazepam blocks arousal of the cortical and limbic system, thereby exerting its sedative and hypnotic effect.
NCI

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endotel cévní

Single pavement layer of cells which line the luminal surface of the entire vascular system and regulate the transport of macromolecules and blood components from interstitium to lumen; this function has been most intensively studied in the blood capillaries.
MSH

single pavement layer of cells which line the luminal surface of the cardiovascular system and regulate the transport of macromolecules and blood components from interstitium to lumen.
CSP

Single pavement layer of cells which line the luminal surface of the entire vascular system and regulate the transport of macromolecules and blood components from interstitium to lumen. (MeSH)
NCI

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ophthalmia neonatorum

Acute conjunctival inflammation in the newborn, usually caused by maternal gonococcal infection. The causative agent is NEISSERIA GONORRHOEAE. The baby`s eyes are contaminated during passage through the birth canal.
MSH

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kanibalismus

Eating other individuals of one`s own species.
MSH

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stadia vývoje bezobratlých

the series of stages in form and functional activity through which an organism passes between successive recurrences of a specified primary stage; a series of stages through which an individual passes during its lifetime.
CSP

The continuous sequence of changes undergone by metamorphosing insects and other animals during the post-embryonic development process.
MSH

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Schistosoma

genus of digenetic trematodes, including the important blood flukes of humans and domestic animals, that cause schistosomiasis; characterized by elongate shape, by separate sexes with marked sexual dimorphism, by their unusual location in the smaller blood vessels of their host, and by utilization of water snails as intermediate hosts.
CSP

A genus of trematode flukes belonging to the family Schistosomatidae. There are over a dozen species. These parasites are found in man and other mammals. Snails are the intermediate hosts.
MSH

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potravinová alergie

gastrointestinal disturbances, skin eruptions, or shock due to allergic reactions to allergens in food.
CSP

An allergy to a substance generally consumed for nutritional purposes.


HL7V3.0

Food allergy is an abnormal response to a food triggered by your body`s immune system. Allergic reactions to food can sometimes cause serious illness and death. Tree nuts and peanuts are the leading causes of deadly allergic reactions called anaphylaxis.

In adults, the foods that most often trigger allergic reactions include

  • Fish and shellfish, such as shrimp, lobster and crab
  • Peanuts
  • Tree nuts, such as walnuts
  • Eggs

Problem foods for children are eggs, milk (especially in infants and young children) and peanuts.

Sometimes a reaction to food is not an allergy. It is often a reaction called "food intolerance". Your immune system does not cause the symptoms of food intolerance. However, these symptoms can look and feel like those of a food allergy.

NIH: National Institute of Allergy and Infectious Diseases


MEDLINEPLUS

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enterohepatický oběh

Recycling through liver by excretion in bile, reabsorption from intestines into portal circulation, passage back into liver, and re-excretion in bile.
MSH

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optika oční

The professional practice of primary eye and vision care that includes the measurement of visual refractive power and the correction of visual defects with lenses or glasses.
MSH

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karbamoylfosfátsynthasa (amoniak)

An enzyme that catalyzes the formation of carbamoyl phosphate from ATP, carbon dioxide, and ammonia. This enzyme is specific for arginine biosynthesis or the urea cycle. Absence or lack of this enzyme may cause CARBAMOYL-PHOSPHATE SYNTHASE I DEFICIENCY DISEASE. EC 6.3.4.16.
MSH

mitochondrial urea cycle enzyme which catalyzes the formation of carbamoylphosphate (a precursor of arginine and pyrimidines) from ammonia deficiency causes hyperammonemia type II.
CSP

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lněný olej

The fixed oil obtained from the dried ripe seed of linseed, Linum usitatissimum (L. Linaceae). It is used as an emollient in liniments, pastes, and medicinal soaps, and in veterinary medicine as a laxative. It is also called flaxseed oil. (Dorland, 28th ed)
MSH

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školy lékařské

Educational institutions for individuals specializing in the field of medicine.
MSH

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Forceps

A manual surgical instrument for general use is a nonpowered, hand-held, or hand-manipulated device, either reusable or disposable, intended to be used in various general surgical procedures. The device includes the applicator, clip applier, biopsy brush, manual dermabrasion brush, scrub brush, cannula, ligature carrier, chisel, clamp, contractor, curette, cutter, dissector, elevator, skin graft expander, file, forceps, gouge, instrument guide, needle guide, hammer, hemostat, amputation hook, ligature passing and knot-tying instrument, knife, blood lancet, mallet, disposable or reusable aspiration and injection needle, disposable or reusable suturing needle, osteotome, pliers, rasp, retainer, retractor, saw, scalpel blade, scalpel handle, one-piece scalpel, snare, spatula, stapler, disposable or reusable stripper, stylet, suturing apparatus for the stomach and intestine, measuring tape, and calipers. A surgical instrument that has specialized uses in a specific medical specialty is classified in separate regulations in Parts 868 through 892.
SPN

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organizační kultura

Beliefs and values shared by all members of the organization. These shared values are reflected in the day to day operations of the organization.
MSH

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karboanhydrasa II

A cytosolic carbonic anhydrase isoenzyme found widely distributed in cells of almost all tissues. Deficiencies of carbonic anhydrase II produce a syndrome characterized by OSTEOPETROSIS, renal tubular acidosis (ACIDOSIS, RENAL TUBULAR) and cerebral calcification. EC 4.2.1.-
MSH

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lipoproteiny

Lipid-protein complexes involved in the transportation and metabolism of lipids in the body. They are spherical particles consisting of a hydrophobic core of TRIGLYCERIDES and CHOLESTEROL ESTERS surrounded by a layer of hydrophilic free CHOLESTEROL; PHOSPHOLIPIDS; and APOLIPOPROTEINS. Lipoproteins are classified by their varying buoyant density and sizes.
MSH

An important class of serum proteins in which a spherical hydrophobic core of triglycerides or cholesterol esters surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins. Classified according to density: chylomicrons, large low density particles, very low density, low density and high density species. Important in lipid transport, especially cholesterol transport in the blood stream. Abnormalities in lipoprotein metabolism have been implicated in certain heart diseases. (On-line Medical Dictionary)
NCI

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skopoletin

Plant growth factor derived from the root of Scopolia carniolica or Scopolia japonica.
MSH

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fosfomycin

An antibiotic produced by Streptomyces fradiae.
MSH

A phosphoenolpyruvate analogue and a synthetic broad-spectrum antibiotic with antimicrobial and bactericidal properties. Fosfomycin binds to and inactivates the enzyme enolpyruvate transferase. This leads to an irreversible blockage of the condensation of uridine diphosphate-N-acetylglucosamine with p-enolpyruvate, which is one of the first steps of bacterial cell wall synthesis, thereby eventually causing cell lysis and bacterial cell death.
NCI

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Orphenadrine Citrate

The citrate salt form of orphenadrine with a muscle relaxant property. Although the mechanism of action has not been fully elucidated, orphenadrine citrate appears to block cholinergic receptors, thereby interfering with the transmission of nerve impulses from the spinal cord to the muscles. It does not produce myoneural block, nor does it affect crossed extensor reflexes.
NCI

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karcinom bazocelulární

A malignant skin neoplasm that seldom metastasizes but has potentialities for local invasion and destruction. Clinically it is divided into types: nodular, cicatricial, morphaic, and erythematoid (pagetoid). They develop on hair-bearing skin, most commonly on sun-exposed areas. Approximately 85% are found on the head and neck area and the remaining 15% on the trunk and limbs. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1471)
MSH

malignant skin neoplasm that seldom metastasizes but has potential for local invasion and destruction; clinically it is divided into types: nodular, cicatricial, morphaic, and erythematoid (pagetoid); develops on hair-bearing skin, most commonly on sun exposed areas.
CSP

Cancer that begins in the lower part of the epidermis (the outer layer of the skin). It may appear as a small white or flesh-colored bump that grows slowly and may bleed. Basal cell cancers are usually found on areas of the body exposed to the sun. Basal cell cancers rarely metastasize (spread) to other parts of the body. They are the most common form of skin cancer.
NCI

a kind of skin cancer
CHV

The most frequently seen skin cancer. It arises from basal cells of the epidermis and pilosebaceous units. Clinically it is divided into the following types: nodular, ulcerative, superficial, multicentric, erythematous, and sclerosing or morphea-like.. More than 95% of these carcinomas occur in patients over 40. They develop on hair-bearing skin, most commonly on sun-exposed areas. Approximately 85% are found on the head and neck and the remaining 15% on the trunk and extremities. Basal cell carcinoma usually grows in a slow and indolent fashion. However, if untreated, the tumor may invade the subcutaneous fat, skeletal muscle and bone. Distant metastases are rare. Excision, curettage and irradiation cure most basal cell carcinomas.
NCI

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alkoholická cirhóza jater

FIBROSIS of the hepatic parenchyma due to chronic excess ALCOHOL DRINKING.
MSH

liver disease in alcoholics in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.
CSP

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tělo – sekrety

Endogenous substances produced through the activity of intact cells of glands, tissues, or organs.
MSH

Body substance in a liquid or semisolid state produced by an exocrine gland. Example: saliva, sebum, blood, plasma, semen, urine.
FMA

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svoboda

The rights of individuals to act and make decisions without external constraints.
MSH

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osteitis fibrosa cystica

A fibrous degeneration, cyst formation, and the presence of fibrous nodules in bone, usually due to HYPERPARATHYROIDISM.
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kardioplegické roztoky

Solutions which, upon administration, will temporarily arrest cardiac activity. They are used in the performance of heart surgery.
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Lolium

Common member of the Gramineae family used as cattle fodder. It harbors several fungi and other parasites toxic to livestock and people and produces allergenic compounds, especially in its pollen. The most commonly seen varieties are L. perenne, L. multiflorum, and L. rigidum.
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