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Agorafobie bez panické poruchy v anamnéze

An anxiety disorder characterized by agoraphobia in the absence of a history of panic attacks; the individual fears incapacitation or humiliation in open, public places or situations due to panic-like symptoms rather than a full-blown panic attack.
NCI

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protilátky – rozmanitost

The phenomenon of immense variability characteristic of ANTIBODIES. It enables the IMMUNE SYSTEM to react specifically against the essentially unlimited kinds of ANTIGENS it encounters. Antibody diversity is accounted for by three main theories: (1) the Germ Line Theory, which holds that each antibody-producing cell has genes coding for all possible antibody specificities, but expresses only the one stimulated by antigen; (2) the Somatic Mutation Theory, which holds that antibody-producing cells contain only a few genes, which produce antibody diversity by mutation; and (3) the Gene Rearrangement Theory, which holds that antibody diversity is generated by the rearrangement of IMMUNOGLOBULIN VARIABLE REGION gene segments during the differentiation of the ANTIBODY-PRODUCING CELLS.
MSH

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Q beta replikasa

An enzyme that catalyzes the replication of the RNA of coliphage Q beta. EC 2.7.7.-.
MSH

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Kartagenerův syndrom

An autosomal recessive disorder characterized by a triad of DEXTROCARDIA; INFERTILITY; and SINUSITIS. The syndrome is caused by mutations of DYNEIN genes encoding motility proteins which are components of sperm tails, and CILIA in the respiratory and the reproductive tracts.
MSH

A rare autosomal recessive inherited syndrome characterized by situs inversus, bronchiectasis, and chronic sinusitis. There is a defect in the function of the cilia that line the respiratory tract.
NCI

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exo-1,4-alfa-glukosidasa

An enzyme that catalyzes the hydrolysis of terminal 1,4-linked alpha-D-glucose residues successively from non-reducing ends of polysaccharide chains with the release of beta-glucose. It is also able to hydrolyze 1,6-alpha-glucosidic bonds when the next bond in sequence is 1,4.
MSH

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cyclopropane

C3H6; a flammable moderately toxic narcotic colorless gas used in organic synthesis and as an anesthetic.
CSP

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alanin

A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
MSH

non-essential amino acid that occurs in high levels in its free state in plasma; it is involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and the central nervous system.
CSP

Amino acid with side chain -CH3.
NCI

A small non-essential amino acid in humans, Alanine is one of the most widely used for protein construction and is involved in the metabolism of tryptophan and vitamin pyridoxine. Alanine is an important source of energy for muscles and central nervous system, strengthens the immune system, helps in the metabolism of sugars and organic acids, and displays a cholesterol-reducing effect in animals. (NCI04)
NCI

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antigeny diferenciační B-lymfocytární

Membrane antigens associated with maturation stages of B-lymphocytes, often expressed in tumors of B-cell origin.
MSH

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chinonreduktasy

NAD(P)H:(quinone acceptor) oxidoreductases. A family that includes three enzymes which are distinguished by their sensitivity to various inhibitors. EC 1.6.99.2 (NAD(P)H DEHYDROGENASE (QUINONE);) is a flavoprotein which reduces various quinones in the presence of NADH or NADPH and is inhibited by dicoumarol. EC 1.6.99.5 (NADH dehydrogenase (quinone)) requires NADH, is inhibited by AMP and 2,4-dinitrophenol but not by dicoumarol or folic acid derivatives. EC 1.6.99.6 (NADPH dehydrogenase (quinone)) requires NADPH and is inhibited by dicoumarol and folic acid derivatives but not by 2,4-dinitrophenol.
MSH

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keratóza seboroická

Benign eccrine poromas that present as multiple oval, brown-to-black plaques, located mostly on the chest and back. The age of onset is usually in the fourth or fifth decade.
MSH

A common benign skin neoplasm usually affecting older individuals. The lesions usually are multiple and arise in the face, chest, and shoulders. They appear as black or brown, slightly elevated skin lesions.
NCI

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Extrapyramidová porucha

defects in basal ganglia function; characterized by changes in muscle tone, poverty of voluntary movements (akinesia), or abnormal involuntary movements (dyskinesia).
CSP

A movement disorder caused by defects in the basal ganglia. The clinical manifestations include changes in the muscle tone, dyskinesia, and akinesia. Causes include vascular disorders, degenerative disorders, and antipsychotic drugs.
NCI

A disorder characterized by abnormal, repetitive, involuntary muscle movements, frenzied speech and extreme restlessness.
NCI

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cysteinproteinasy – inhibitory

Exogenous and endogenous compounds which inhibit CYSTEINE ENDOPEPTIDASES.
MSH

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alkuronium

A non-depolarizing skeletal muscle relaxant similar to TUBOCURARINE. It is used as an anesthesia adjuvant.
MSH

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antitumorózní kombinovaná chemoterapie – protokoly

The use of two or more chemicals simultaneously or sequentially in the drug therapy of neoplasms. The drugs need not be in the same dosage form.
MSH

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záření – látky senzibilizující

Drugs used to potentiate the effectiveness of radiation therapy in destroying unwanted cells.
MSH

chemotherapeutic agent used to enhance the effect of radiation therapy.
CSP

Drugs that make tumor cells more sensitive to radiation therapy.
NCI

An agent that makes tumor cells more sensitive to radiation therapy.
NCI

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ledviny – dřeň

The internal portion of the kidney, consisting of striated conical masses, the renal pyramids, whose bases are adjacent to the cortex and whose apices form prominent papillae projecting into the lumen of the minor calyces.
MSH

internal portion of the kidney, consisting of striated conical masses, the renal pyramids, whose bases are adjacent to the cortex and whose apices form prominent papillae projecting into the lumen of the minor calyces.
CSP

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oční řasy

The hairs which project from the edges of the EYELIDS.
MSH

Anyone of the short hairs that grow on the edge of the eyelid.
NCI

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cytochromy b

cytochromes of the b group that have alpha-band absorption of 563-564 nm and occur as subunits in mitochondrial electron transport complex III.
CSP

Cytochromes of the b group that have alpha-band absorption of 563-564 nm. They occur as subunits in MITOCHONDRIAL ELECTRON TRANSPORT COMPLEX III.
MSH

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alkylsulfonany

any compound of the type R-SO3-.
CSP

Organic esters or salts of sulfonic acid derivatives containing an aliphatic hydrocarbon radical.
MSH

An ester of alkane sulfonic acid that acts as an alkylating agent.
NCI

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anus – nemoci

The anus is the opening of the rectum through which stool passes out of your body. Problems with the anus are common. They include hemorrhoids, abscesses, fissures (cracks), and cancer.

Many people are embarrassed to talk about anal troubles. But seeing your doctor about problems in this area is important. This is especially true if you have pain or bleeding. Treatments vary widely depending on the particular problem.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases


MEDLINEPLUS

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radioligandová zkouška

Quantitative determination of receptor (binding) proteins in body fluids or tissue using radioactively labeled binding reagents (e.g., antibodies, intracellular receptors, plasma binders).
MSH

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Klebsiella – infekce

Infections with bacteria of the genus KLEBSIELLA.
MSH

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faktor X – nedostatek

Blood coagulation disorder usually inherited as an autosomal recessive trait, though it can be acquired. It is characterized by defective activity in both the intrinsic and extrinsic pathways, impaired thromboplastin time, and impaired prothrombin consumption.
MSH

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cytoplazma

The part of a cell that contains the CYTOSOL and small structures excluding the CELL NUCLEUS; MITOCHONDRIA; and large VACUOLES. (Glick, Glossary of Biochemistry and Molecular Biology, 1990)
MSH

protoplasm of a cell exclusive of that of the nucleus; it consists of a continuous aqueous solution (cytosol) and the organelles and inclusions suspended in it (phaneroplasm), and is the site of most of the chemical activities of the cell.
CSP

The fluid inside a cell but outside the cell`s nucleus. Most chemical reactions in a cell take place in the cytoplasm.
NCI

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684]
GO

Cell component which has as its direct parts a portion of cytosol and one or more organelles. Examples: cytoplasm of hepatocyte, cytoplasm of erythrocyte, cytoplasm of thrombocyte, cytoplasm of neuron.
FMA

Cell substance which consists of cytosol and cytoplasmic organelles.
UWDA

That portion of the cell contained within the plasma membrane but excluding the nucleus.
NCI

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mucinóza folikulární

A disease of the pilosebaceous unit, presenting clinically as grouped follicular papules or plaques with associated hair loss. It is caused by mucinous infiltration of tissues, and usually involving the scalp, face, and neck. It may be primary (idiopathic) or secondary to mycosis fungoides or reticulosis.
MSH

A rare dermatologic disorder characterized by the accumulation of mucinous material in the hair follicles. In some cases it is associated with lymphoproliferative disorders, most often mycosis fungoides and Hodgkin lymphoma.
NCI

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afázie

A cognitive disorder marked by an impaired ability to comprehend or express language in its written or spoken form. This condition is caused by diseases which affect the language areas of the dominant hemisphere. Clinical features are used to classify the various subtypes of this condition. General categories include receptive, expressive, and mixed forms of aphasia.
MSH

cognitive disorder marked by an impaired ability to comprehend or express language in its written or spoken form; caused by diseases which affect the language areas of the dominant hemisphere; general categories include receptive, expressive, and mixed forms of aphasia.
CSP

Aphasia is a disorder caused by damage to the parts of the brain that control language. It can make it hard for you to read, write and say what you mean to say. It is most common in adults who have had a stroke. Brain tumors, infections, injuries and dementia can also cause it. The type of problem you have and how bad it is depends on which part of your brain is damaged and how much damage there is.

There are four main types:

  • Expressive aphasia – you know what you want to say, but you have trouble saying or writing what you mean
  • Receptive aphasia – you hear the voice or see the print, but you can`t make sense of the words
  • Anomic aphasia – you have trouble using the correct word for objects, places or events
  • Global aphasia – you can`t speak, understand speech, read or write

Some people recover from aphasia without treatment. Most, however, need language therapy as soon as possible.

NIH: National Institute of Neurological Disorders and Stroke


MEDLINEPLUS

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náhodné rozdělení

A process involving chance used in therapeutic trials or other research endeavor for allocating experimental subjects, human or animal, between treatment and control groups, or among treatment groups. It may also apply to experiments on inanimate objects.
MSH

When referring to an experiment or clinical trial, the process by which animal or human subjects are assigned by chance to separate groups that compare different treatments or other interventions. Randomization gives each participant an equal chance of being assigned to any of the groups.
NCI

The process of assigning trial subjects to treatment or control groups using an element of chance to determine the assignments in order to reduce bias. NOTE: Unequal randomization is used to allocate subjects into groups at a differential rate; for example, three subjects may be assigned to a treatment group for every one assigned to the control group. [ICH E6 1.48] See also balanced study. (CDISC glossary)
NCI

The allocation of individuals to groups by chance, especially in order to control the variables in an experiment.
NCI

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kynurenin

aromatic aminoacid formed as an intermediate in the metabolism of tryptophan.
CSP

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famotidin

A competitive histamine H2-receptor antagonist. Its main pharmacodynamic effect is the inhibition of gastric secretion.
MSH

A propanimidamide and histamine H2-receptor antagonist with antacid activity. As a competitive inhibitor of histamine H2-receptors located on the basolateral membrane of the parietal cell, famotidine reduces basal and nocturnal gastric acid secretion, resulting in a reduction in gastric volume, acidity, and amount of gastric acid released in response to various stimuli.
NCI

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data – zobrazování

The visual display of data in a man-machine system. An example is when data is called from the computer and transmitted to a CATHODE RAY TUBE DISPLAY or LIQUID CRYSTAL display.
MSH

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