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zdravotnické služby

Services for the diagnosis and treatment of disease and the maintenance of health.
MSH

providing services for the diagnosis, prevention and treatment of disease and the maintenance of health.
CSP

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nemoc – stupeň závažnosti

Levels of severity of illness within a diagnostic group which are established by various measurement criteria.
MSH

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určování pohlaví – analýza

Validation of the SEX of an individual by inspection of the GONADS and/or by genetic tests.
MSH

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midodrin

An ethanolamine derivative that is an adrenergic alpha-1 agonist. It is used as a vasoconstrictor agent in the treatment of HYPOTENSION.
MSH

A direct-acting prodrug and sympathomimetic agent with antihypotensive properties. Midodrine is converted to its active metabolite, desglymidodrine by deglycination reaction. Desglymidodrine selectively binds to and activates alpha-1-adrenergic receptors of the arteriolar and venous vasculature. This causes smooth muscle contraction and leads to an elevation of blood pressure. Desglymidodrine diffuses poorly across the blood-brain barrier, and is therefore not associated with effects on the central nervous system (CNS).
NCI

Price: $1.00

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kyslík – radioisotopy

Unstable isotopes of oxygen that decay or disintegrate emitting radiation. O atoms with atomic weights 13, 14, 15, 19, and 20 are radioactive oxygen isotopes.
MSH

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cer – radioisotopy

Unstable isotopes of cerium that decay or disintegrate emitting radiation. Ce atoms with atomic weights 132-135, 137, 139, and 141-148 are radioactive cerium isotopes.
MSH

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srdeční frekvence fetální

The heart rate of the FETUS. The normal range at term is between 120 and 160 beats per minute.
MSH

The number of fetal cardiac beats per minute.
NCI

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Shigella boydii

One of the SHIGELLA species that produces bacillary dysentery (DYSENTERY, BACILLARY).
MSH

A species of facultatively anaerobic, Gram negative, rod shaped bacteria in the phylum Proteobacteria. This species is nonmotile, non spore forming, catalase positive, oxidase negative and has mixed indole reactivity. S. boydii is found only on the Indian subcontinent and is pathogenic, being a causative agent of shigellosis in primates.
NCI

Any bacterial organism that can be assigned to the species Shigella boydii.
NCI

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Minocycline Hydrochloride

The hydrochloride salt of minocycline, a broad spectrum long-acting derivative of the antibiotic tetracycline, with antibacterial and anti-inflammatory activities. Minocycline binds to the bacterial 30S ribosomal subunit and interferes with the binding of tRNA to the ribosomal complex, thereby inhibiting protein translation in bacteria. In addition, minocycline inhibits the inflammatory enzyme 5-lipoxygenase (5LOX) and may impede T cell-microglia interactions; both activities may contribute to minocycline`s neuroprotective effects. 5LOX catalyzes the synthesis of inflammatory mediators such as prostaglandins and leukotrienes.
NCI

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kardiostimulátor

A device designed to stimulate, by electric impulses, contraction of the heart muscles. It may be temporary (external) or permanent (internal or internal-external).
MSH

An electronic device that is implanted in the body to monitor heart rate and rhythm. It gives the heart electrical stimulation when it does not beat normally. It runs on batteries and has long, thin wires that connect it to the heart.
NCI

Price: $1.00

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chalony

Peptides that inhibit mitosis (ANTIMITOTICS). During the 1960`s the term referred to crude extracts that inhibited cell proliferation; the activity was later attributed to PYROGLUTAMATE type oligopeptides.
MSH

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Hela buňky

first continuously cultured human malignant cell line, derived from a cervical carcinoma; used for virus cultivation and antitumor drug screening assays.
CSP

The first continuously cultured human malignant CELL LINE, derived from the cervical carcinoma of Henrietta Lacks. These cells are used for VIRUS CULTIVATION and antitumor drug screening assays.
MSH

HeLa cells were developed from cervix adenocarcinoma of a 31-year-old Black female. The cells are positive for keratin by immunoperoxidase staining. HeLa cells have been reported to contain human papilloma virus 18 (HPV-18) sequences. P53 expression was reported to be low, and normal levels of pRB (retinoblastoma suppressor) were found. Four typical HeLa marker chromosomes have been reported. M1 is a rearranged long arm and centromere of chromosome 1 and the long arm of chromosome 3. M2 is a combination of short arm of chromosome 3 and long arm of chromosome 5. M3 is an isochromosome of the short arm of chromosome 5. M4 consists of the long arm of chromosome 11 and an arm of chromosome 19. HeLa Marker Chromosomes: One copy of Ml, one copy of M2, four-five copies of M3, and two copies of M4 as revealed by G-banding patterns.
NCI

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sialorea

Increased salivary flow.
MSH

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mitóza

A type of CELL NUCLEUS division by means of which the two daughter nuclei normally receive identical complements of the number of CHROMOSOMES of the somatic cells of the species.
MSH

A cell cycle process comprising the steps by which a cell progresses through M phase, the part of the cell cycle comprising nuclear division. [GOC:dph, GOC:mah, ISBN:0815316194]
GO

A cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell. [GOC:dph, GOC:ma, GOC:mah, ISBN:0198547684]
GO

The last cell cycle stage during which the replicated daughter chromosomes separate in to separate nuclei; cytokinesis then occurs to produce separate daughter cells. It is divided into Prophase, Metaphase, Anaphase, and Telophase.
NCI

The process by which a single parent cell divides to make two new daughter cells. Each daughter cell receives a complete set of chromosomes from the parent cell. This process allows the body to grow and replace cells.
NCI

The usual process of somatic reproduction of cells consisting of a sequence of modifications of the nucleus that result in the formation of two daughter cells with exactly the same chromosome and DNA content as that of the original cell. It is the process by which the body grows and replaces cells and is divided into four phases. In Prophase, paired chromosomes form, nuclear membrane disappears, the achromatic spindle appears, and polar bodies form. In Metaphase, chromosomes are arranged in the equatorial plane of the central spindle to form the monaster and chromosomes separate into exactly similar halves. In Anaphase, the two groups of daughter chromosomes separate and move along the fibers of the central spindle, each toward one of the asters, forming the diaster. In Telophase, the daughter chromosomes resolve themselves into a reticulum, the daughter nuclei are formed, and the cytoplasm divides forming two complete daughter cells.
NCI

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kyseliny palmitové

A group of 16-carbon fatty acids that contain no double bonds.
MSH

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chemie farmaceutická

Chemistry dealing with the composition and preparation of agents having PHARMACOLOGIC ACTIONS or diagnostic use.
MSH

A chemistry-based discipline, also involving aspects of biological, medical and pharmaceutical sciences. It is concerned with the invention, discovery, design, identification and preparation of biologically active compounds, the study of their metabolism, the interpretation of their mode of action at the molecular level and the construction of structure-activity relationships. (Glossary of Terms Used in Medicinal Chemistry)
NCI

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hematochezie

The passage of bright red blood from the rectum. The blood may or may not be mixed with formed stool in the form of blood, blood clots, bloody stool or diarrhea.
MSH

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Bombyx

A genus of silkworm MOTHS in the family Bombycidae of the order LEPIDOPTERA. The family contains a single species, Bombyx mori from the Greek for silkworm + mulberry tree (on which it feeds). A native of Asia, it is sometimes reared in this country. It has long been raised for its SILK and after centuries of domestication it probably does not exist in nature. It is used extensively in experimental GENETICS. (From Borror et al., An Introduction to the Study of Insects, 4th ed, p519)
MSH

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Moldavsko

A country in Eastern Europe, northeast of Romania. (NCI)
NCI

A country in Eastern Europe, northeast of Romania. (CIA World Factbook 2002)
NCI

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Pancuronium Bromide

The bromide salt form of pancuronium, a synthetic, long-acting ammonio steroid muscle relaxant with curarimimetic, some antimuscarinic and sympathomimetic effects. Pancuronium bromide competitively binds to the nicotinic receptor at the neuromuscular junction, thereby preventing acetylcholine binding and resulting in skeletal muscle relaxation and paralysis.
NCI

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péče o dítě

Care of children in the home or institution.
MSH

care of children in the home or institution; for the raising of one`s own children or parenting use CHILD REARING
CSP

Children`s healthy development depends on safe and positive experiences when they are very young. If you work or go to school, you want to know that your child is in good hands while you are away. You may choose in-home care, where the caregiver comes to your home. Or your child might go to the caregiver`s home. Finally, there are child care centers. You need to choose the one that works for your family.

It is important to get to know your child`s caregivers. They will be a big part of your child`s life. The caregiver`s training should involve

  • Knowledge of how young children learn and grow
  • Positive, consistent discipline
  • Knowledge of the signs that a child is sick
  • Cleanliness and safety practices to help keep kids from getting sick or hurt
  • Basic first aid


MEDLINEPLUS

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hemochromatóza

WHAT: Hemochromatosis: Hemochromatosis: a disorder of iron metabolism characterized by excess deposition of iron in the tissues, especially the liver. It is characterized by pigmentation of the skin, hepatic cirrhosis, decreased carbohydrate tolerance, cardiomyopathy and endocrinopathy (especially hypogonadism). Mainly seen in men over the age of 40 years. It has an associated arthropathy distinguished by involvement of the metacarpophalangeal joints (particularly the second and third), wrists, knees, shoulders, and hips. There is often an associated chondrocalcinosis.
AIR

A disorder due to the deposition of hemosiderin in the parenchymal cells, causing tissue damage and dysfunction of the liver, pancreas, heart, and pituitary. Full development of the disease in women is restricted by menstruation, pregnancy, and lower dietary intake of iron. Acquired hemochromatosis may be the result of blood transfusions, excessive dietary iron, or secondary to other disease. Idiopathic or genetic hemochromatosis is an autosomal recessive disorder of metabolism associated with a gene tightly linked to the A locus of the HLA complex on chromosome 6. (From Dorland, 27th ed)
MSH

condition in which there is a deviation or interruption in the storage of iron in the body.
CSP

Hemochromatosis is an inherited disease in which too much iron builds up in your body. It is one of the most common genetic diseases in the United States.

Iron is a mineral found in many foods. Your body normally absorbs about 10 percent of the iron in the food you eat. If you have hemochromatosis, you absorb more iron than you need. Your body has no natural way to get rid of the extra iron. It stores it in body tissues, especially the liver, heart and pancreas. The extra iron can damage your organs. Without treatment, it can cause your organs to fail.

The most common treatment is to remove some blood, just like when you donate blood. This is called therapeutic phlebotomy. Medicines may also help remove the extra iron. Your doctor might suggest some changes in your diet.

NIH: National Heart, Lung, and Blood Institute


MEDLINEPLUS

An inherited metabolic disorder characterized by iron accumulation in the tissues.
NCI

A condition in which the body takes up and stores more iron than it needs. The extra iron is stored in the liver, heart, and pancreas, which may cause liver disease, heart problems, organ failure, and cancer. It may also cause bronze skin, diabetes, pain in the joints and abdomen, tiredness, and impotence. Hemochromatosis may be inherited, or it may be caused by blood transfusions.
NCI

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virus opičí imunodeficience

causes a disease, SAIDS, in monkeys which is similar to AIDS in man; used as a model for HIV infection.
CSP

An HIV-like virus that infects monkeys, chimpanzees, and other non-human primates. (AIDS Info HIV Glossary)
NCI

Species of the genus LENTIVIRUS, subgenus primate immunodeficiency viruses (IMMUNODEFICIENCY VIRUSES, PRIMATE), that induces acquired immunodeficiency syndrome in monkeys and apes (SAIDS). The genetic organization of SIV is virtually identical to HIV.
MSH

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opice

Any haplorhine primate not belonging to the family Tarsiidae, Hylobatidae, Pongidae, or Hominidae; this does not correspond to any taxon. This group is divided into Old World monkeys (Cercopithecidae) and New World monkeys (Callitrichidae and Cebidae). Many types are used as an experimental model for human disease and drug testing.
NCI

A non-taxonomic, non-specific term for the smaller longer-tailed PRIMATES.
MSH

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Paracoccidioides

A mitosporic fungal genus. P. brasiliensis (previously Blastomyces brasiliensis) is the etiologic agent of PARACOCCIDIOIDOMYCOSIS.
MSH

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Chironomidae

family of nonbiting midges, in the order Diptera; salivary glands of the genus Chironomus are used in studies of cellular genetics and biochemistry.
CSP

A family of nonbiting midges, in the order DIPTERA. Salivary glands of the genus Chironomus are used in studies of cellular genetics and biochemistry.
MSH

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hemolyticko-uremický syndrom

A syndrome that is associated with microvascular diseases of the KIDNEY, such as RENAL CORTICAL NECROSIS. It is characterized by hemolytic anemia (ANEMIA, HEMOLYTIC); THROMBOCYTOPENIA; and ACUTE RENAL FAILURE.
MSH

A form of thrombotic microangiopathy with renal failure, hemolytic anemia, and severe thrombocytopenia.
NCI

A disorder characterized by a form of thrombotic microangiopathy with renal failure, hemolytic anemia, and severe thrombocytopenia.
NCI

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lebka – fraktury

Fractures of the skull which may result from penetrating or nonpenetrating head injuries or rarely BONE DISEASES (see also FRACTURES, SPONTANEOUS). Skull fractures may be classified by location (e.g., SKULL FRACTURE, BASILAR), radiographic appearance (e.g., linear), or based upon cranial integrity (e.g., SKULL FRACTURE, DEPRESSED).
MSH

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morfinany

Compounds based on a partially saturated iminoethanophenanthrene, which can be described as ethylimino-bridged benzo-decahydronaphthalenes. They include some of the OPIOIDS found in PAPAVER that are used as ANALGESICS.
MSH

parent substance of morphine alkaloids.
CSP

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paranoidní porucha osobnosti

A personality disorder characterized by the avoidance of accepting deserved blame and an unwarranted view of others as malevolent. The latter is expressed as suspiciousness, hypersensitivity, and mistrust.
MSH

A disorder characterized by an enduring pattern of behavior based on the pervasive belief that the motives of others are malevolent and that they should not be trusted.
NCI

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