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hypertriglyceridémie

A condition of elevated levels of TRIGLYCERIDES in the blood.
MSH

condition of elevated triglyceride concentration in the blood; an inherited form occurs in familial hyperlipoproteinemia IIb and hyperlipoproteinemia type IV; linked to higher risk of heart disease and arteriosclerosis.
CSP

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rutamycin

A macrolide antibiotic of the oligomycin group, obtained from Streptomyces rutgersensis. It is used in cytochemistry as a tool to inhibit various ATPases and to uncouple oxidative phosphorylation from electron transport and also clinically as an antifungal agent.
MSH

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antikonvulzíva

Drugs used to prevent SEIZURES or reduce their severity.
MSH

agent used to prevent seizures or reduce their severity.
CSP

Medicine to stop, prevent, or control seizures (convulsions).
NCI

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poměr šancí

The ratio of two odds. The exposure-odds ratio for case control data is the ratio of the odds in favor of exposure among cases to the odds in favor of exposure among noncases. The disease-odds ratio for a cohort or cross section is the ratio of the odds in favor of disease among the exposed to the odds in favor of disease among the unexposed. The prevalence-odds ratio refers to an odds ratio derived cross-sectionally from studies of prevalent cases.
MSH

A measure of the odds of an event happening in one group compared to the odds of the same event happening in another group. In cancer research, odds ratios are most often used in case-control (backward looking) studies to find out if being exposed to a certain substance or other factor increases the risk of cancer. For example, researchers may study a group of individuals with cancer (cases) and another group without cancer (controls) to see how many people in each group were exposed to a certain substance or factor. They calculate the odds of exposure in both groups and then compare the odds. An odds ratio of one means that both groups had the same odds of exposure and, therefore, the exposure probably does not increase the risk of cancer. An odds ratio of greater than one means that the exposure may increase the risk of cancer, and an odds ratio of less than one means that the exposure may reduce the risk of cancer.
NCI

The ratio of the odds of an event occurring in one group to the odds of it occurring in another group, or to a sample-based estimate of that ratio.
NCI

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noviny

Publications printed and distributed daily, weekly, or at some other regular and usually short interval, containing news, articles of opinion (as editorials and letters), features, advertising, and announcements of current interest. (Webster`s 3d ed)
MSH

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Cypriniformes

An order of fish with 26 families and over 3,000 species. This order includes the families CYPRINIDAE (minnows and CARPS), Cobitidae (loaches), and Catostomidae (suckers).
MSH

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hypofosfatémie familiární

An inherited condition of abnormally low serum levels of PHOSPHATES (below 1 mg/liter) which can occur in a number of genetic diseases with defective reabsorption of inorganic phosphorus by the PROXIMAL RENAL TUBULES. This leads to phosphaturia, HYPOPHOSPHATEMIA, and disturbances of cellular and organ functions such as those in X-LINKED HYPOPHOSPHATEMIC RICKETS; OSTEOMALACIA; and FANCONI SYNDROME.
MSH

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salicylate

o-hydroxybenzoate.
CSP

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antigeny T-independentní

Antigens which may directly stimulate B lymphocytes without the cooperation of T lymphocytes.
MSH

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čichové dráhy

Set of nerve fibers conducting impulses from olfactory receptors to the cerebral cortex. It includes the OLFACTORY NERVE; OLFACTORY BULB; olfactory tract, olfactory tubercle, anterior perforated substance, and olfactory cortex. The term rhinencephalon is restricted to structures in the CNS receiving fibers from the olfactory bulb.
MSH

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nimorazol

An antitrichomonal agent which is effective either topically or orally and whose urinary metabolites are also trichomonicidal.
MSH

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cystinurie

An inherited disorder due to defective reabsorption of CYSTINE and other BASIC AMINO ACIDS by the PROXIMAL RENAL TUBULES. This form of aminoaciduria is characterized by the abnormally high urinary levels of cystine; LYSINE; ARGININE; and ORNITHINE. Mutations involve the amino acid transport protein gene SLC3A1.
MSH

inherited abnormality of renal tubular transport of dibasic amino acids leading to massive urinary excretion of cystine, lysine, arginine, and ornithine.
CSP

An autosomal recessive inherited metabolic disorder caused by mutations in the SLC3A1 and SLC7A9 genes. It is characterized by deficient re-absorption of cystine in the proximal tubules of the kidney. It results in the formation of stones in the kidney, ureter, and urinary bladder.
NCI

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Disociační fuga

subtype of hysterical neurosis; the current classification is dissociative disorders; sudden temporary alterations in the normally integrative functions of consciousness.
CSP

A disorder characterized by sudden, unexpected travel away from one`s home or place of work accompanied by an inability to recall one`s past; the individual is confused about his or her personal identity and may assume a new identity.
NCI

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salpingitida

Inflammation of the uterine salpinx, the trumpet-shaped FALLOPIAN TUBES, usually caused by ascending infections of organisms from the lower reproductive tract. Salpingitis can lead to tubal scarring, hydrosalpinx, tubal occlusion, INFERTILITY, and ectopic pregnancy (PREGNANCY, ECTOPIC)
MSH

inflammation of the fallopian tubes.
CSP

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antipyrin

An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
MSH

family of N-phenylpyrazolones with nonnarcotic analgesic properties.
CSP

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viry onkogenní

Viruses that produce tumors.
MSH

viruses that produce tumors; see RTs for specific organisms.
CSP

A virus capable of transforming a cell to a malignant phenotype. (BioTech Life Science Dictionary)
NCI

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oxid dusičitý

Nitrogen oxide (NO2). A highly poisonous gas. Exposure produces inflammation of lungs that may only cause slight pain or pass unnoticed, but resulting edema several days later may cause death. (From Merck, 11th ed) It is a major atmospheric pollutant that is able to absorb UV light that does not reach the earth`s surface.
MSH

Found in the atmosphere as a key ingredient in photochemical formation of smog and acid rain, Nitrogen Dioxide is a poisonous gas that forms during combustion. Toxic at high concentrations, it reacts with moisture in the air to form nitric acid, highly corrosive and hazardous to plants and animals. (NCI04)
NCI

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cytogenetika

A subdiscipline of genetics which deals with the cytological and molecular analysis of the CHROMOSOMES, and location of the GENES on chromosomes, and the movements of chromosomes during the CELL CYCLE.
MSH

subdiscipline of genetics which deals with the cytological and molecular analysis of the chromosomes, and location of the genes on chromosomes, and the movements of chromosomes during the cell cycle.
CSP

The study of the structure, function, and abnormalities of human chromosomes.
NCI

The branch of biology that studies the cellular aspects of heredity, especially the chromosomes. Includes the study of disease states caused by numerical and structural chromosome abnormalities.
NCI

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imunoglobulin D

present on the membrane of many circulating B lymphocytes; may play a role in antigen triggered lymphocyte differentiation.
CSP

An immunoglobulin which accounts for less than 1% of plasma immunoglobulin. It is found on the membrane of many circulating B LYMPHOCYTES.
MSH

An immunoglobulin isotype (subclass). This isotype is expressed on naive B cells along with IgM. Little is known about its physiologic role.
NCI

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sarin

An organophosphorus ester compound that produces potent and irreversible inhibition of cholinesterase. It is toxic to the nervous system and is a chemical warfare agent.
MSH

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syndromy aortálního oblouku

Conditions resulting from abnormalities in the arteries branching from the ASCENDING AORTA, the curved portion of the aorta. These syndromes are results of occlusion or abnormal blood flow to the head-neck or arm region leading to neurological defects and weakness in an arm. These syndromes are associated with vascular malformations; ATHEROSCLEROSIS; TRAUMA; and blood clots.
MSH

A syndrome resulting from structural defects of the arteries that arise from the aortic arch. Signs and symptoms include weakness, dizziness, arm numbness, blurred vision and transient ischemic attacks.
NCI

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opisthorchiáza

Infection with flukes of the genus Opisthorchis.
MSH

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nociceptory

Peripheral AFFERENT NEURONS which are sensitive to injuries or pain, usually caused by extreme thermal exposures, mechanical forces, or other noxious stimuli. Their cell bodies reside in the DORSAL ROOT GANGLIA. Their peripheral terminals (NERVE ENDINGS) innervate target tissues and transduce noxious stimuli via axons to the CENTRAL NERVOUS SYSTEM.
MSH

receptor for pain caused by damage to body tissue.
CSP

A free nerve ending that is a receptor for painful stimuli. (Kanner)
NCI

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cytotoxiny

Substances that are toxic to cells; they may be involved in immunity or may be contained in venoms. These are distinguished from CYTOSTATIC AGENTS in degree of effect. Some of them are used as CYTOTOXIC ANTIBIOTICS. The mechanism of action of many of these are as ALKYLATING AGENTS or MITOSIS MODULATORS.
MSH

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napodobovací chování

The mimicking of the behavior of one individual by another.
MSH

mimicking a behavior of one individual by another.
CSP

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ESKIZOFRENIA, EDOZEIN MOTA

A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.
MSH

class of psychoses with disturbance mainly of cognition (content and form of thought, perception, sense of self versus external world, volition) and psychomotor function, rather than affect.
CSP

Schizophrenia is a severe, lifelong brain disorder. People who have it may hear voices, see things that aren`t there or believe that others are reading or controlling their minds. In men, symptoms usually start in the late teens and early 20s. They include hallucinations, or seeing things, and delusions such as hearing voices. For women, they start in the mid-20s to early 30s. Other symptoms include

  • Unusual thoughts or perceptions
  • Disorders of movement
  • Difficulty speaking and expressing emotion
  • Problems with attention, memory and organization

No one is sure what causes schizophrenia, but your genetic makeup and brain chemistry probably play a role. Medicines can relieve many of the symptoms, but it can take several tries before you find the right drug. You can reduce relapses by staying on your medicine for as long as your doctor recommends. With treatment, many people improve enough to lead satisfying lives.

NIH: National Institute of Mental Health


MEDLINEPLUS

A group of severe mental disorders in which a person has trouble telling the difference between real and unreal experiences, thinking logically, having normal emotional responses to others, and behaving normally in social situations. Symptoms include seeing, hearing, feeling things that are not there, having false ideas about what is taking place or who one is, nonsense speech, unusual behavior, lack of emotion, and social withdrawal.
NCI

A major psychotic disorder characterized by abnormalities in the perception or expression of reality. It affects the cognitive and psychomotor functions. Common clinical signs and symptoms include delusions, hallucinations, disorganized thinking, and retreat from reality.
NCI

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apoferritiny

The protein components of ferritins. Apoferritins are shell-like structures containing nanocavities and ferroxidase activities. Apoferritin shells are composed of 24 subunits, heteropolymers in vertebrates and homopolymers in bacteria. In vertebrates, there are two types of subunits, light chain and heavy chain. The heavy chain contains the ferroxidase activity.
MSH

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orbita – fraktury

Fractures of the bones in the orbit, which include parts of the frontal, ethmoidal, lacrimal, and sphenoid bones and the maxilla and zygoma.
MSH

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normetanefrin

A methylated metabolite of norepinephrine that is excreted in the urine and found in certain tissues. It is a marker for tumors.
MSH

3-methylnorepinephrine, a metabolite of epinephrine excreted in urine.
CSP

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DDT

A polychlorinated pesticide that is resistant to destruction by light and oxidation. Its unusual stability has resulted in difficulties in residue removal from water, soil, and foodstuffs. This substance may reasonably be anticipated to be a carcinogen: Fourth Annual Report on Carcinogens (NTP-85-002, 1985). (From Merck Index, 11th ed)
MSH

insecticide that came into prominence during and after World War II; for a time it proved very effective, but insect populations rapidly developed tolerance for it, hence much of its original effectiveness has been lost; general usage is now widely discouraged because of the toxicity that results from the environmental persistence of this agent.
CSP

A white, odorless and tasteless, very stable, water-insoluble, synthetic, crystalline chlorinated hydrocarbon that is soluble in most organic solvents, fat and oils and tends to accumulate in ecosystems. DDT was once widely used as a pesticide to control insects in agriculture and to control malaria, typhus and body lice, but its use is now limited. Exposure to DDT mainly affects the nervous system resulting in tremors, dizziness, nausea, incoordination, convulsions and seizures. This substance is reasonably anticipated to be a human carcinogen based on evidence of carcinogenicity in experimental animals. (NCI05)
NCI

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