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pilotní projekty

Small-scale tests of methods and procedures to be used on a larger scale if the pilot study demonstrates that these methods and procedures can work.
MSH

The initial study examining a new method or treatment.
NCI

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polycystické ledviny – nemoci

hereditary diseases that are characterized by the progressive expansion of a large number of tightly packed cysts within the kidney; there is an autosomal recessive form appearing in childhood and a later appearing autosomal dominant form; a similar acquired disease sometimes accompanies end-stage renal disease.
CSP

A usually autosomal dominant and less frequently autosomal recessive genetic disorder characterized by the presence of numerous cysts in the kidneys leading to end-stage renal failure. The autosomal dominant trait is associated with abnormalities on the short arm of chromosome 16. Symptoms in patients with the autosomal dominant trait usually appear at middle age and include abdominal pain, hematuria, and high blood pressure. Patients may develop brain aneurysms and liver cysts. Patients with the autosomal recessive trait present with progressive renal failure early in life and symptoms resulting from hepatic fibrosis. The autosomal recessive trait is associated with abnormalities of chromosome 6. Polycystic kidney disease may also result as a side effect in patients on renal dialysis.
NCI

Hereditary diseases that are characterized by the progressive expansion of a large number of tightly packed CYSTS within the KIDNEYS. They include diseases with autosomal dominant and autosomal recessive inheritance.
MSH

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nervus facialis

The 7th cranial nerve. The facial nerve has two parts, the larger motor root which may be called the facial nerve proper, and the smaller intermediate or sensory root. Together they provide efferent innervation to the muscles of facial expression and to the lacrimal and salivary glands, and convey afferent information for taste from the anterior two-thirds of the tongue and for touch from the external ear.
MSH

seventh cranial nerve; has two parts, the larger motor root which may be called the facial nerve proper, and the smaller intermediate or sensory root, which together provide efferent innervation to the muscles of facial expression and to the lacrimal and salivary glands, and convey afferent information for taste from the anterior two-thirds of the tongue and for touch from the external ear.
CSP

The 7th cranial nerve. The facial nerve has two parts, the larger motor root which may be called the facial nerve proper, and the smaller intermediate or sensory root. Together they provide efferent innervation to the muscles of facial expression and to the lacrimal and salivary glands, and convey afferent information for taste from the anterior two-thirds of the tongue and for touch from the external ear. (MeSH)
NCI

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supratentoriální nádory

Primary and metastatic (secondary) tumors of the brain located above the tentorium cerebelli, a fold of dura mater separating the CEREBELLUM and BRAIN STEM from the cerebral hemispheres and DIENCEPHALON (i.e., THALAMUS and HYPOTHALAMUS and related structures). In adults, primary neoplasms tend to arise in the supratentorial compartment, whereas in children they occur more frequently in the infratentorial space. Clinical manifestations vary with the location of the lesion, but SEIZURES; APHASIA; HEMIANOPSIA; hemiparesis; and sensory deficits are relatively common features. Metastatic supratentorial neoplasms are frequently multiple at the time of presentation.
MSH

A benign or malignant neoplasm that occurs within the intracranial cavity above the tentorium cerebelli.
NCI

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chromafinní systém

The cells of the body which stain with chromium salts. They occur along the sympathetic nerves, in the adrenal gland, and in various other organs.
MSH

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hypofýza – přední lalok

The anterior glandular lobe of the pituitary gland, also known as the adenohypophysis. It secretes the ADENOHYPOPHYSEAL HORMONES that regulate vital functions such as GROWTH; METABOLISM; and REPRODUCTION.
MSH

The glandular or anterior lobe of the pituitary gland which secretes several hormones.
NCI

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znalostní báze

A database or other collection of knowledge expressed in a formal knowledge representation language.
NCI

Collections of facts, assumptions, beliefs, and heuristics that are used in combination with databases to achieve desired results, such as a diagnosis, an interpretation, or a solution to a problem (From McGraw Hill Dictionary of Scientific and Technical Terms, 6th ed).
MSH

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fakulta

The teaching staff and members of the administrative staff having academic rank in an educational institution.
MSH

The body of teachers and administrators at a school.
NCI

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chirurgické nástroje

Hand-held tools or implements used by health professionals for the performance of surgical tasks.
MSH

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chromozomální poruchy

clinical conditions caused by an abnormal chromosome constitution in which there is extra or missing chromosome material, either a whole chromosome or a chromosome segment.
CSP

Clinical conditions caused by an abnormal chromosome constitution in which there is extra or missing chromosome material (either a whole chromosome or a chromosome segment). (from Thompson et al., Genetics in Medicine, 5th ed, p429)
MSH

A disorder that results from a chromosomal abnormality.
NCI

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plankton

Community of tiny aquatic PLANTS and ANIMALS, and photosynthetic BACTERIA, that are either free-floating or suspended in the water, with little or no power of locomotion. They are divided into PHYTOPLANKTON and ZOOPLANKTON.
MSH

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porodní doba druhá

The period of OBSTETRIC LABOR that is from the complete dilatation of the CERVIX UTERI to the expulsion of the FETUS.
MSH

A stage during labor and childbirth when the cervix is effaced totally and remains dilated until the birth of the baby.
NCI

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Fasciola

A genus of trematode liver flukes of the family Fasciolidae. Two species of this genus are F. hepatica and F. gigantica. The parasites are found in the liver and gallbladder and associated ducts in mammals and occasionally man. F. gigantica occurs rarely in man.
MSH

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prasata – nemoci

Diseases of domestic swine and of the wild boar of the genus Sus.
MSH

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chromozómy lidské, pár 4

A specific pair of GROUP B CHROMOSOMES of the human chromosome classification.
MSH

The designation for each member of the fourth largest human autosomal chromosome pair. Chromosome 4 spans more than 186 million base pairs and represents between 6 and 6.5% of the total DNA in normal diploid cells.
NCI

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Plasmodium berghei

protozoan parasite of rodents transmitted by the mosquito Anopheles dureni.
CSP

A protozoan parasite of rodents transmitted by the mosquito Anopheles dureni.
MSH

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laktoferrin

An iron-binding protein that was originally characterized as a milk protein. It is widely distributed in secretory fluids and is found in the neutrophilic granules of LEUKOCYTES. The N-terminal part of lactoferrin possesses a serine protease which functions to inactivate the type III secretion system used by bacteria to export virulence proteins for host cell invasion.
MSH

iron binding protein found in the specific granules of neutrophils where it exerts an antimicrobial activity by withholding iron from ingested bacteria and fungi; occurs in many excretions and exudates.
CSP

Lactotransferrin (710 aa, ~78 kDa) is encoded by the human LTF gene. This protein is involved in the mediation of both proteolysis and iron transport.
NCI

A protein that is found in milk, tears, mucus, bile, and some white blood cells and is being studied in the treatment and prevention of cancer. It is involved in fighting against infection and inflammation and it acts as an antioxidant.
NCI

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GOROTZ INKONTINENTZIA

Failure of voluntary control of the anal sphincters, with involuntary passage of feces and flatus.
MSH

failure of control of the anal sphincters, with involuntary passage of feces and flatus; it may be either psychogenic or organic in origin.
CSP

Inability to control the escape of stool from the rectum.
NCI

A disorder characterized by inability to control the escape of stool from the rectum.
NCI

Bowel incontinence is the inability to control your bowels. When you feel the urge to have a bowel movement, you may not be able to hold it until you get to a toilet. More than 5.5 million Americans have bowel incontinence. It affects people of all ages – children and adults. It is more common in women and older adults, but it is not a normal part of aging.

Causes include

Treatments include changes in diet, medicines, bowel training, or surgery.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases


MEDLINEPLUS

Inability to hold stool in the rectum.
NCI

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syfilis kardiovaskulární

Cardiovascular manifestations of SYPHILIS, an infection of TREPONEMA PALLIDUM. In the late stage of syphilis, sometimes 20-30 years after the initial infection, damages are often seen in the blood vessels including the AORTA and the AORTIC VALVE. Clinical signs include syphilitic aortitis, aortic insufficiency, or aortic ANEURYSM.
MSH

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chinovník

A genus of rubiaceous South American trees that yields the toxic CINCHONA ALKALOIDS from their bark; QUININE; QUINIDINE; chinconine, cinchonidine and others are used to treat malaria and cardiac arrhythmias.
MSH

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Pleomorphism

Having different forms at different stages of the life cycle.
NCI

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Laos

A country in Southeastern Asia, northeast of Thailand, west of Vietnam. (NCI)
NCI

A country in Southeastern Asia, northeast of Thailand, west of Vietnam. (CIA World Factbook 2002)
NCI

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fenbendazol

Antinematodal benzimidazole used in veterinary medicine.
MSH

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Taenia

A genus of large tapeworms.
MSH

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Cladosporium

A mitosporic Loculoascomycetes fungal genus including some economically important plant parasites. Teleomorphs include Mycosphaerella and Venturia.
MSH

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pneumonie rickettsiální

Pneumonia caused by infection with bacteria of the family RICKETTSIACEAE.
MSH

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Lathyrus

A plant genus in the family FABACEAE known for LATHYRISM poisoning.
MSH

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Ferula

A plant genus of the family APIACEAE. It contains pungent oils and resins. It is used to flavor curries, as a carminative, and as cat and dog repellent. The occasionally used common name of `giant fennel` should not be confused with true fennel (FOENICULUM).
MSH

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tau-krystaliny

A type of crystallin that has been found in the lens (LENS, CRYSTALLINE) of certain species of VERTEBRATES. They are inactivated form of PHOSPHOPYRUVATE HYDRATASE.
MSH

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kloacin

A bacteriocin produced by a plasmid that can occur in several bacterial strains. It is a basic protein of molecular weight 56,000 and exists in a complex with its immunity protein which protects the host bacterium from its effects.
MSH

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