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scimitar syndrom

An anomalous pulmonary venous return in which the right PULMONARY VEIN is not connected to the LEFT ATRIUM but to the INFERIOR VENA CAVA. Scimitar syndrome is named for the crescent- or Turkish sword-like shadow in the chest radiography and is often associated with hypoplasia of the right lung and right pulmonary artery, and dextroposition of the heart.
MSH

A rare congenital cardiopulmonary defect characterized by abnormal right-sided pulmonary venous drainage and right lung malformations.
NCI

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organoterapie

Historically, the treatment of disease by the administration of animal organs or their extracts (after Brown-Sequard). At present synthetic preparations substitute for the extracts of a gland. (From Stedman, 26th ed)
MSH

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hmyzí hormony

Hormones secreted by insects. They influence their growth and development. Also synthetic substances that act like insect hormones.
MSH

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glucarpidase

A bacterial enzyme that breaks down proteins and other substances, including methotrexate. It is being studied in the treatment of toxic effects caused by methotrexate. It may also help activate certain drugs to kill cancer cells. It is a type of chemoprotective agent and a type of prodrug activator.
NCI

A zinc-dependent enzyme isolated from a strain of the bacterium Pseudomonas. Because glucarpidase rapidly hydrolyzes methotrexate into inactive metabolites, it may be useful as a rescue agent for methotrexate-induced nephrotoxicity. In antibody-directed enzyme prodrug therapy (ADEPT), this agent is conjugated with an antibody that binds to a specific tumor cell type, allowing for glucarpidase-catalyzed activation of a co-administered prodrug at the site of the tumor.
NCI

A zinc-dependent enzyme isolated from a strain of the bacterium Pseudomonas. Because carboxypeptidase-G2 rapidly hydrolyzes methotrexate into inactive metabolites, it may be useful as a rescue agent for methotrexate-induced nephrotoxicity. In antibody-directed enzyme prodrug therapy (ADEPT), this agent is conjugated with an antibody that binds to a specific tumor cell type, allowing for carboxypeptidase-G2-catalyzed activation of a co-administered prodrug at the site of the tumor. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=41665&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=41665&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C346″ NCI Thesaurus)
PDQ

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mořské sasanky

The order Actiniaria, in the class ANTHOZOA, comprised of large, solitary polyps. All species are carnivorous.
MSH

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virus chřipky B

A negative-strand linear single-strand RNA virus with an 8 segment genome. Virions are enveloped and usually spherical or pleomorphic, 50-120 nm in diameter. Influenza B viruses are usually found only in humans. Unlike influenza A viruses, these viruses are not classified according to subtype.
NCI

Species of the genus INFLUENZAVIRUS B that cause HUMAN INFLUENZA and other diseases primarily in humans. Antigenic variation is less extensive than in type A viruses (INFLUENZA A VIRUS) and consequently there is no basis for distinct subtypes or variants. Epidemics are less likely than with INFLUENZA A VIRUS and there have been no pandemics. Previously only found in humans, Influenza B virus has been isolated from seals which may constitute the animal reservoir from which humans are exposed.
MSH

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insulin – rezistence

Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.
MSH

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karcinom skirhotický

An adenocarcinoma with a hard (Greek skirrhos, hard) structure owing to the formation of dense connective tissue in the stroma. (From Dorland, 27th ed)
MSH

An infiltrating adenocarcinoma characterized by the presence of desmoplastic stromal reaction.
NCI

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selenomethionin

Diagnostic aid in pancreas function determination.
MSH

methionine in which selenium replaces the sulfur atom; the radioactive form is used in tests of tissue uptake of methionine.
CSP

A selenium (Se) analogue of methionine in which sulfur is replaced with the trace element selenium. Selenomethionine (SeMet) can incorporate into proteins in place of methionine with no effects on protein structure and function, providing a mechanism for reversible Se storage in organs and tissues. Free selenium is incorporated into selenocysteine, an amino acid found in more than thirty selenoproteins including the glutathione peroxidases (GPx) enzymes, thioredoxin reductase (TR) and the iodothyronine deiodinase enzymes.
NCI

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osteochondrom

A cartilage-capped benign tumor that often appears as a stalk on the surface of bone. It is probably a developmental malformation rather than a true neoplasm and is usually found in the metaphysis of the distal femur, proximal tibia, or proximal humerus. Osteochondroma is the most common of benign bone tumors.
MSH

A common, benign cartiliginous neoplasm arising from the metaphysis of bone. The tumor grows on the surface of the bone; it may be pedunculated or sessile. It is characterized by the presence of chondrocytes, a cartilage cap, and a fibrous perichondrium that extends to the periosteum of the bone. In some cases, there is deletion of 8q24.1 chromosome locus.
NCI

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inteligenční testy

Standardized tests that measure the present general ability or aptitude for intellectual performance.
MSH

standardized tests which measure a wide range of abilities, including verbal, numerical and social competence; includes Stanford-Binet test, Wechsler-Bellevue scale and Wechsler Intelligence scale.
CSP

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karfecilin

The phenyl ester of CARBENICILLIN that, upon oral administration, is broken down in the intestinal mucosa to the active antibacterial. It is used for urinary tract infections.
MSH

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epidermolysis bullosa

Group of genetically determined disorders characterized by the blistering of skin and mucosae. There are four major forms: acquired, simple, junctional, and dystrophic. Each of the latter three has several varieties.
MSH

inherited chronic noninflammatory skin disease manifested by vesicles, large bullae (blisters), and skin erosions which often result from trauma.
CSP

An autosomal recessive inherited skin disorder caused by mutations in the genes encoding keratins 5 and 14, collagen VII or laminin 5. It is characterized by skin fragility and the formation of blisters. The blisters may become large and ulcerated, resulting in skin infections and loss of body fluids.
NCI

A group of chronic skin disorders in which fluid-filled blisters form on the skin and mucosa (the moist, inner lining of some organs and body cavities). Epidermolysis bullosa is inherited and usually starts at birth. Patients with epidermolysis bullosa may be at increased risk of squamous cell cancer of the skin.
NCI

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Senegal

A republic in western Africa, southwest of MAURITANIA and east of MALI. Its capital is Dakar.
MSH

A country in Western Africa, bordering the North Atlantic Ocean, between Guinea-Bissau and Mauritania. (NCI)
NCI

A country in Western Africa, bordering the North Atlantic Ocean, between Guinea-Bissau and Mauritania. (CIA World Factbook 2002)
NCI

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otolaryngologie

A surgical specialty concerned with the study and treatment of disorders of the ear, nose, and throat.
MSH

A medical specialty concerned with the study and treatment of disorders of the ear, nose, and throat.
NCI

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intermitentní explozivní porucha

A disorder characterized by recurrent episodes of serious assaultive acts or destruction of property due to a failure to resist aggressive impulses; the degree of aggression during these episodes is grossly out of proportion to any psychosocial provocation. The aggressive episodes are not etiologically linked to another mental disorder, a general medical condition, or substance use.
NCI

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chrupavka

A non-vascular form of connective tissue composed of CHONDROCYTES embedded in a matrix that includes CHONDROITIN SULFATE and various types of FIBRILLAR COLLAGEN. There are three major types: HYALINE CARTILAGE; FIBROCARTILAGE; and ELASTIC CARTILAGE.
MSH

nonvascular form of connective tissue composed of chondrocytes embedded in a matrix of type II collagen and chondroitin sulfate; divided into three types: hyaline cartilage, fibrocartilage, and yellow or elastic white fibrocartilage.
CSP

A tough, flexible tissue that lines joints and gives structure to the nose, ears, larynx, and other parts of the body.
NCI

Regular connective tissue, which consists of chondrocytes and related cells, the intercellular matrix of which is chondrified. Examples: hyaline cartilage, fibrocartilage, elastic cartilage.
FMA

A type of connective tissue composed of chondrocytes and an extracellular matrix, composed of collagen, elastin, and ground substance. There are three types of cartilage; namely elastic, hyaline, and fibrocartilage.
NCI

A tough, elastic, fibrous connective tissue found in various parts of the body, such as the joints, outer ear, and larynx.
CHV

Regular connective tissue, which consists of chondrocytes and related cells, the intercellular matrix of which is chondrified. Examples: hyaline cartilage, fibrocartilage, elastic cartilage.
UWDA

A type of connective tissue composed of chondrocytes and an extracellular matrix, composed of collagen, elastin, and ground substance. There are three types of cartilage; namely elastic, hyaline, and fibrocartilage.
NCI

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epoxidové pryskyřice

Organic compounds containing an epoxide group and characterized by strength and thermosetting properties. Epoxy resins are often used as dental materials.
MSH

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sérotypizace

distinguishing microorganisms by the kinds and combinations of constituent antigens present in the cell.
CSP

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vlastnictví

The legal relation between an entity (individual, group, corporation, or-profit, secular, government) and an object. The object may be corporeal, such as equipment, or completely a creature of law, such as a patent; it may be movable, such as an animal, or immovable, such as a building.
MSH

The legal relation in which a person or group entity has a financial interest in, dominion of, or control over an object or property.
NCI

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střevní nádory

Tumors or cancer of the INTESTINES.
MSH

new abnormal intestinal tissue, small and large intestines, that grows by excessive cellular division and proliferation more rapidly than normal and continues to grow after the stimuli that initiated the new growth cease.
CSP

A benign or malignant neoplasm involving the small or large intestine.
NCI

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sumci

Common name of the order Siluriformes. This order contains many families and over 2,000 species, including venomous species. Heteropneustes and Plotosus genera have dangerous stings and are aggressive. Most species are passive stingers.
MSH

snout contains 1-4 pairs barbels, small eyes, flattened head, adipose fin; streamlined body shape, either without scales or is covered by heavy, bony plates.
CSP

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ergotismus

Poisoning caused by ingesting ergotized grain or by the misdirected or excessive use of ergot as a medicine.
MSH

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určování pohlaví – analýza

Validation of the SEX of an individual by inspection of the GONADS and/or by genetic tests.
MSH

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kyslík – radioisotopy

Unstable isotopes of oxygen that decay or disintegrate emitting radiation. O atoms with atomic weights 13, 14, 15, 19, and 20 are radioactive oxygen isotopes.
MSH

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inventář nemocniční

Materials and equipment in stock; includes drugs in pharmacies, blood in blood banks, etc.
MSH

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proteinkinasa CDC28, S cerevisiae

A protein kinase encoded by the Saccharomyces cerevisiae CDC28 gene and required for progression from the G1 PHASE to the S PHASE in the CELL CYCLE.
MSH

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prekursorové erytroidní buňky

The cells in the erythroid series derived from MYELOID PROGENITOR CELLS or from the bi-potential MEGAKARYOCYTE-ERYTHROID PROGENITOR CELLS which eventually give rise to mature RED BLOOD CELLS. The erythroid progenitor cells develop in two phases: erythroid burst-forming units (BFU-E) followed by erythroid colony-forming units (CFU-E); BFU-E differentiate into CFU-E on stimulation by ERYTHROPOIETIN, and then further differentiate into ERYTHROBLASTS when stimulated by other factors.
MSH

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Shigella boydii

One of the SHIGELLA species that produces bacillary dysentery (DYSENTERY, BACILLARY).
MSH

A species of facultatively anaerobic, Gram negative, rod shaped bacteria in the phylum Proteobacteria. This species is nonmotile, non spore forming, catalase positive, oxidase negative and has mixed indole reactivity. S. boydii is found only on the Indian subcontinent and is pathogenic, being a causative agent of shigellosis in primates.
NCI

Any bacterial organism that can be assigned to the species Shigella boydii.
NCI

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kardiostimulátor

A device designed to stimulate, by electric impulses, contraction of the heart muscles. It may be temporary (external) or permanent (internal or internal-external).
MSH

An electronic device that is implanted in the body to monitor heart rate and rhythm. It gives the heart electrical stimulation when it does not beat normally. It runs on batteries and has long, thin wires that connect it to the heart.
NCI

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