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adjuvancia imunologická

Substances that augment, stimulate, activate, potentiate, or modulate the immune response at either the cellular or humoral level. The classical agents (Freund`s adjuvant, BCG, Corynebacterium parvum, et al.) contain bacterial antigens. Some are endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Their mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy of many biological response modifiers is related to their antigen-specific immunoadjuvanticity.
MSH

A drug that stimulates the immune system to respond to disease.
NCI

a drug that stimulates the immune system
CHV

A substance that increases the ability of the immune system to fight infection and disease.
NCI

Substances that stimulate the immune system.
NCI

Adjuvants are mostly pharmacological agents of drug or biological origin used to modify the antigenicity of immunization components, i.e., to stimulate, potentiate, or depress the immune response or to inhibit or enhance specific subclasses of immunocytes. Adjuvants augment, stimulate, activate, potentiate, or modulate the immune response at either the cellular or humoral level. Classical agents (Freund`s adjuvant, BCG, Corynebacterium parvum) contain bacterial antigens. Some adjuvants are endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Their mode of action is either non-specific, resulting in increased immune responsiveness to a variety of antigens, or antigen-specific, affecting a restricted type of immune response to a narrow group of antigens. Since adjuvants enhance the body`s immune response, they can be considered a type of immune modulator.
NCI

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Congress (U.S. Legislature)

The U.S. legislature, consisting of the Senate and the House of Representatives. (American Heritage Dictionary)
NCI

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plicní surfaktanty

Substances and drugs that lower the SURFACE TENSION of the mucoid layer lining the PULMONARY ALVEOLI.
MSH

phospholipids secreted by the great alveolar cells into alveoli and respiratory air passages which contributes to the elastic property of pulmonary tissue.
CSP

Secretion produced by Type 2 pulmonary alveolar cell.
FMA

Pulmonary surfactant lines the lung epithelium and lowers surface tension to prevent collapse at end-expiration. Deficiency of pulmonary surfactant results in respiratory distress syndrome (RDS) in premature infants. Lung surfactant is synthesized in alveolar type II cells, stored in lamellar bodies and secreted via exocytosis. (NCI)
NCI

Secretion produced by Type 2 pulmonary alveolar cell.
UWDA

Pulmonary surfactant lines the lung epithelium and lowers surface tension to prevent collapse at end-expiration. Deficiency of pulmonary surfactant results in respiratory distress syndrome (RDS) in premature infants. Lung surfactant is synthesized in alveolar type II cells, stored in lamellar bodies and secreted via exocytosis.
NCI

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Lathyrus

A plant genus in the family FABACEAE known for LATHYRISM poisoning.
MSH

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Ferula

A plant genus of the family APIACEAE. It contains pungent oils and resins. It is used to flavor curries, as a carminative, and as cat and dog repellent. The occasionally used common name of `giant fennel` should not be confused with true fennel (FOENICULUM).
MSH

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nadledviny – nemoci

Pathological processes of the ADRENAL GLANDS.
MSH

pathologic condition or abnormal functioning of either or both of the paired glands situated in the retroperitoneal tissues at the superior pole of the kidneys or adrenal glands.
CSP

Your adrenal, or suprarenal, glands are located on the top of each kidney. These glands produce hormones that you can`t live without, including sex hormones and cortisol, which helps you respond to stress and has many other functions.

Adrenal disorders can cause your adrenal glands to make too much or not enough hormones. With Cushing`s syndrome, there`s too much cortisol, while with Addison`s disease, there is too little. Some people are born unable to make enough cortisol. Tumors can also cause disorders in your adrenal glands. Bleeding and infection can cause an adrenal gland problem that can be fatal without quick treatment.

Treatment depends on which problem you have. Surgery or medicines can treat many adrenal gland disorders.


MEDLINEPLUS

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spokojenost zákazníků

Customer satisfaction or dissatisfaction with a benefit or service received.
MSH

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puromycinaminonukleosid

PUROMYCIN derivative that lacks the methoxyphenylalanyl group on the amine of the sugar ring. It is an antibiotic with antineoplastic properties and can cause nephrosis.
MSH

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stehno a bérec – kosti

The bones of the free part of the lower extremity in humans and of any of the four extremities in animals. It includes the FEMUR; PATELLA; TIBIA; and FIBULA.
MSH

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fibrinová tkáňová adheziva

An autologous or commercial tissue adhesive containing FIBRINOGEN and THROMBIN. The commercial product is a two component system from human plasma that contains more than fibrinogen and thrombin. The first component contains highly concentrated fibrinogen, FACTOR VIII, fibronectin, and traces of other plasma proteins. The second component contains thrombin, calcium chloride, and antifibrinolytic agents such as APROTININ. Mixing of the two components promotes BLOOD CLOTTING and the formation and cross-linking of fibrin. The tissue adhesive is used for tissue sealing, HEMOSTASIS, and WOUND HEALING.
MSH

A substance used during surgery to help heal wounds. It contains proteins found in human blood that cause blood to clot. When fibrin sealant is placed on a wound, a clot forms. Fibrin sealant is being studied as a way to improve healing after lymph node removal in patients with cancer. It is a type of surgical glue.
NCI

A plasma-derived fibrin biomatrix preparation consisting of two separate solutions that are combined on application. The sealer protein solution contains clottable human fibrinogen and bovine aprotinin, a fibrinolysis inhibitor; the thrombin solution contains human thrombin and calcium chloride. When the solutions are combined, a clot is formed, reproducing the final stages of the coagulation cascade. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=38531&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=38531&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2664″ NCI Thesaurus)
PDQ

A plasma-derived fibrin biomatrix preparation consisting of two separate solutions that are combined on application. The sealer protein solution contains clottable human fibrinogen and bovine aprotinin, a fibrinolysis inhibitor; the thrombin solution contains human thrombin and calcium chloride. When the solutions are combined, a clot is formed, reproducing the final stages of the coagulation cascade.
NCI

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aerobik

exercise designed to improve an individual`s cardiovascular condition.
CSP

Physical activity that increases the heart rate and the body`s use of oxygen. It helps improve a person`s physical fitness.
NCI

Sustained exercise that places an increased oxygen demand on the cardiovascular system and promotes an increased efficiency of the body`s use of oxygen.
NCI

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kontrolní skupiny

Groups that serve as a standard for comparison in experimental studies. They are similar in relevant characteristics to the experimental group but do not receive the experimental intervention.
MSH

In a clinical trial, the group that does not receive the new treatment being studied. This group is compared to the group that receives the new treatment, to see if the new treatment works.
NCI

A group used as a standard of comparison in a control experiment.
NCI

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pyrazinamid

A pyrazine that is used therapeutically as an antitubercular agent.
MSH

antibacterial derived from nicotinic acid, used as a tuberculostatic.
CSP

A synthetic pyrazinoic acid amide derivative with bactericidal property. Pyrazinamide is particularly active against slowly multiplying intracellular bacilli (unaffected by other drugs) by an unknown mechanism of action. Its bactericidal action is dependent upon the presence of bacterial pyrazinamidase, which removes the amide group to produce active pyrazinoic acid. Pyrazinamide is an important component of multidrug therapy for tuberculosis. (NCI04)
NCI

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Leishmania mexicana

A parasitic hemoflagellate of the subgenus Leishmania leishmania that infects man and animals including rodents. The Leishmania mexicana complex causes both cutaneous (LEISHMANIASIS, CUTANEOUS) and diffuse cutaneous leishmaniasis (LEISHMANIASIS, DIFFUSE CUTANEOUS) and includes the subspecies amazonensis, garnhami, mexicana, pifanoi, and venezuelensis. L. m. mexicana causes chiclero ulcer, a form of cutaneous leishmaniasis (LEISHMANIASIS, CUTANEOUS) in the New World. The sandfly, Lutzomyia, appears to be the vector.
MSH

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Fidži

A republic consisting of an island group in Melanesia, in the southwest Pacific Ocean. Its capital is Suva. It was discovered by Abel Tasman in 1643 and was visited by Captain Cook in 1774. It was used by escaped convicts from Australia as early as 1804. It was annexed by Great Britain in 1874 but achieved independence in 1970. The name Fiji is of uncertain origin. In its present form it may represent that of Viti, the main island in the group. (From Webster`s New Geographical Dictionary, 1988, p396 & Room, Brewer`s Dictionary of Names, 1992, p186)
MSH

An island group in the South Pacific Ocean, about two-thirds of the way from Hawaii to New Zealand. (NCI)
NCI

An island group in the South Pacific Ocean, about two-thirds of the way from Hawaii to New Zealand. (CIA World Factbook 2002)
NCI

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agar

A complex sulfated polymer of galactose units, extracted from Gelidium cartilagineum, Gracilaria confervoides, and related red algae. It is used as a gel in the preparation of solid culture media for microorganisms, as a bulk laxative, in making emulsions, and as a supporting medium for immunodiffusion and immunoelectrophoresis.
MSH

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rohovka – nemoci

Diseases of the cornea.
MSH

pathological process affecting the transparent anterior portion of the fibrous coat of the eye.
CSP

Your cornea is the outermost layer of your eye. It is clear and shaped like a dome. The cornea helps to shield the rest of the eye from germs, dust, and other harmful matter. It also helps your eye to focus. If you wear contact lenses, they float on top of your corneas.

Problems with the cornea include

  • Refractive errors
  • Allergies
  • Infections
  • Injuries
  • Dystrophies – conditions in which parts of the cornea lose clarity due to a buildup of cloudy material

Treatments of corneal disorders include medicines, corneal transplantation and corneal laser surgery.

NIH National Eye Institute


MEDLINEPLUS

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pyrofosfatasy

A group of enzymes within the class EC 3.6.1.- that catalyze the hydrolysis of diphosphate bonds, chiefly in nucleoside di- and triphosphates. They may liberate either a mono- or diphosphate. EC 3.6.1.-.
MSH

nonEC; catalyses the hydrolysis of diphosphate bonds, chiefly in nucleoside di- and triphosphates.
CSP

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androsteny

Unsaturated derivatives of the steroid androstane containing at least one double bond at any site in any of the rings.
MSH

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Leptospira interrogans sérovar icterohaemorrhagiae

A serovar of the bacterial species LEPTOSPIRA INTERROGANS, whose primary host is RATS.
MSH

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rybářství

Places for cultivation and harvesting of fish, particularly in sea waters. (from McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
MSH

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vzduch

The mixture of gases present in the earth`s atmosphere consisting of oxygen, nitrogen, carbon dioxide, and small amounts of other gases.
MSH

A mixture of gases making up the earth`s atmosphere, consisting mainly of nitrogen, oxygen, argon, and carbon dioxide.
NCI

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kortison

A naturally occurring glucocorticoid. It has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. Cortisone itself is inactive. It is converted in the liver to the active metabolite HYDROCORTISONE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p726)
MSH

naturally occurring glucocorticoid used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent; cortisone itself is inactive and is converted in the liver to the active metabolite cortisol.
CSP

A natural steroid hormone produced in the adrenal gland. It can also be made in the laboratory. Cortisone reduces swelling and can suppress immune responses.
NCI

A steroid hormone synthesized and secreted by the adrenal gland and necessary for life. It is involved with maintaining cardiovascular function, blood glucose balance, regulating the inflammatory response and metabolism of proteins, carbohydrates, and fat.
NCI

A corticosteroid with potent glucocorticoid activity. Therapeutic cortisone is the inactive precursor molecule of the active hormone cortisol, which is the hydroxylation product of cortisone by 11-beta-steroid dehydrogenase. Cortisol increases blood pressure and blood sugar levels, and suppresses the immune system, therefore cortisone is used to treat allergies or inflammation.
NCI

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kvalita zdravotní péče

The levels of excellence which characterize the health service or health care provided based on accepted standards of quality.
MSH

activities and programs intended to assure or improve the quality of care in either a defined medical setting or a program; the concept includes the assessment or evaluation of the quality of care; identification of problems or shortcomings in the delivery of care; designing activities to overcome these deficiencies; and follow-up monitoring to ensure effectiveness of corrective steps.
CSP

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anestézie inhalační

Anesthesia caused by the breathing of anesthetic gases or vapors or by insufflating anesthetic gases or vapors into the respiratory tract.
MSH

state characterized by loss of feeling or sensation caused by the breathing of anesthetic gases or vapors or by insufflating anesthetic gases or vapors into the respiratory tract.
CSP

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leukémie bifenotypická akutní

An acute leukemia exhibiting cell features characteristic of both the myeloid and lymphoid lineages and probably arising from MULTIPOTENT STEM CELLS.
MSH

An acute leukemia of ambiguous lineage characterized by blasts which coexpress myeloid and T or B lineage antigens or concurrent B and T lineage antigens. (WHO, 2001)
NCI

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floor (object)

The lower inner surface of an open space or hollow organ.
NCI

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albuterol

A short-acting beta-2 adrenergic agonist that is primarily used as a bronchodilator agent to treat ASTHMA. Albuterol is prepared as a racemic mixture of R(-) and S(+) stereoisomers. The stereospecific preparation of R(-) isomer of albuterol is referred to as levalbuterol.
MSH

short-acting beta2-adrenergic agonist with its main clinical use in asthma.
CSP

asthma inhaler
CHV

A racemic mixture of the r-isomer levalbuterol and s-albuterol, a short-acting sympathomimetic agent with bronchodilator activity. Albuterol stimulates beta-2 adrenergic receptors in the lungs, thereby activating the enzyme adenylate cyclase that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3`,5`-adenosine monophosphate (cAMP). Increased cAMP concentrations relax bronchial smooth muscle, relieve bronchospasms, and reduce inflammatory cell mediator release, especially from mast cells. Albuterol although to a lesser extent, also stimulates beta-1 adrenergic receptors, thereby increasing the force and rate of myocardial contraction.
NCI

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Professional counsellor

A provider who is trained and educated in the performance of behavior health services through interpersonal communications and analysis. Training and education at the specialty level usually requires a master`s degree and clinical experience and supervision for licensure or certification. Sources: Abridged from definitions provided by the National Board of Certified Counselors and the American Association of Pastoral Counselors.


HL7V3.0

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psík mývalovitý

The lone species in the genus Nyctereutes, family CANIDAE. It is found in the woodland zone from southeastern Siberia to Vietnam and on the main islands of Japan.
MSH

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