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pro-opiomelanokortin

A 30-kDa protein synthesized primarily in the ANTERIOR PITUITARY GLAND and the HYPOTHALAMUS. It is also found in the skin and other peripheral tissues. Depending on species and tissues, POMC is cleaved by PROHORMONE CONVERTASES yielding various active peptides including ACTH; BETA-LIPOTROPIN; ENDORPHINS; MELANOCYTE-STIMULATING HORMONES; and others (GAMMA-LPH; CORTICOTROPIN-LIKE INTERMEDIATE LOBE PEPTIDE; N-terminal peptide of POMC or NPP).
MSH

precursor polypeptide from which ACTH, MSH, and beta-lipotropin are produced by posttranslational cleavage.
CSP

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prach

Earth or other matter in fine, dry particles. (Random House Unabridged Dictionary, 2d ed)
MSH

earth or other matter in fine, dry particles; a common allergen.
CSP

A fine powdery material such as dry earth or pollen that can be blown about in the air. (WordNet)
NCI

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kyselina 4-aminobenzoová

A member of the VITAMIN B COMPLEX. It used to be common in SUNSCREENING AGENTS until found to also be a sensitizer. The potassium salt is used therapeutically in fibrotic skin disorders.
MSH

An organic acid with UV absorption and antifibrotic properties. When exposed to light, aminobenzoic acid (para-aminobenzoic acid or PABA) absorbs UV light and emits excess energy via a photochemical reaction that may cause damage to DNA. Because DNA defects contribute to skin cancer, aminobenzoic acid is no longer widely used in sunscreen formulations. Aminobenzoic acid may also increase oxygen uptake at the tissue level and may enhance monoamine oxidase (MAO) activity to promote the degradation of serotonin, which in excess, may lead to fibrotic changes.
NCI

A nutrient in the vitamin B complex that the body needs in small amounts to function and stay healthy. Bacteria that live in the intestines need para-aminobenzoic acid to survive. Para-aminobenzoic acid is found in grains and foods from animals. It is being studied as a radiosensitizer (a substance that makes tumor cells more sensitive to radiation therapy) and in the treatment of certain skin disorders.
NCI

A nutrient in the vitamin B complex that the body needs in small amounts to function and stay healthy. Bacteria that live in the intestines need aminobenzoic acid to survive. Aminobenzoic acid is found in grains and foods from animals. It is being studied as a radiosensitizer (a substance that makes tumor cells more sensitive to radiation therapy) and in the treatment of certain skin disorders.
NCI

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inteligenční testy

Standardized tests that measure the present general ability or aptitude for intellectual performance.
MSH

standardized tests which measure a wide range of abilities, including verbal, numerical and social competence; includes Stanford-Binet test, Wechsler-Bellevue scale and Wechsler Intelligence scale.
CSP

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červenání se

Involuntary reddening, especially of the face, associated with feelings of embarrassment, confusion or shame.
MSH

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proestrus

A phase of the ESTROUS CYCLE that precedes ESTRUS. During proestrus, the Graafian follicles undergo maturation.
MSH

The estrous cycle phase in which there is heightened follicular activity. [GOC:dph, ISBN:0721662544 “Dorland`s Illustrated Medical Dictionary”]
GO

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epidermolysis bullosa

Group of genetically determined disorders characterized by the blistering of skin and mucosae. There are four major forms: acquired, simple, junctional, and dystrophic. Each of the latter three has several varieties.
MSH

inherited chronic noninflammatory skin disease manifested by vesicles, large bullae (blisters), and skin erosions which often result from trauma.
CSP

An autosomal recessive inherited skin disorder caused by mutations in the genes encoding keratins 5 and 14, collagen VII or laminin 5. It is characterized by skin fragility and the formation of blisters. The blisters may become large and ulcerated, resulting in skin infections and loss of body fluids.
NCI

A group of chronic skin disorders in which fluid-filled blisters form on the skin and mucosa (the moist, inner lining of some organs and body cavities). Epidermolysis bullosa is inherited and usually starts at birth. Patients with epidermolysis bullosa may be at increased risk of squamous cell cancer of the skin.
NCI

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PIXA EGITERAKOAN MINA

Painful URINATION. It is often associated with infections of the lower URINARY TRACT.
MSH

Difficulty or pain in urination.
NCI

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kalcimycin

An ionophorous, polyether antibiotic from Streptomyces chartreusensis. It binds and transports CALCIUM and other divalent cations across membranes and uncouples oxidative phosphorylation while inhibiting ATPase of rat liver mitochondria. The substance is used mostly as a biochemical tool to study the role of divalent cations in various biological systems.
MSH

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intermitentní explozivní porucha

A disorder characterized by recurrent episodes of serious assaultive acts or destruction of property due to a failure to resist aggressive impulses; the degree of aggression during these episodes is grossly out of proportion to any psychosocial provocation. The aggressive episodes are not etiologically linked to another mental disorder, a general medical condition, or substance use.
NCI

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kosti – nemoci vývojové

condition in which there is a deviation from or interruption of the normal development of bone and bone tissue.
CSP

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prolaps

The protrusion of an organ or part of an organ into a natural or artificial orifice.
MSH

abnormal lowering of an organ or a part
CHV

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epoxidové pryskyřice

Organic compounds containing an epoxide group and characterized by strength and thermosetting properties. Epoxy resins are often used as dental materials.
MSH

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Echinostomatidae

A family of flukes (TREMATODA) characterized by a collar of spines at their anterior end. The body is elongated and is covered with spines, and the two suckers are usually close together. (Noble et al., Parasitology: the Biology of Animal Parasites, 6th ed, p183)
MSH

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potrat neúplný

Premature loss of PREGNANCY in which not all the products of CONCEPTION have been expelled.
MSH

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střevní nádory

Tumors or cancer of the INTESTINES.
MSH

new abnormal intestinal tissue, small and large intestines, that grows by excessive cellular division and proliferation more rapidly than normal and continues to grow after the stimuli that initiated the new growth cease.
CSP

A benign or malignant neoplasm involving the small or large intestine.
NCI

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boric acid

borates; derivatives of boric acid either B(OH)3 or, preferably H3BO3.
CSP

A weakly acidic hydrate of boric oxide with mild antiseptic, antifungal, and antiviral properties. The exact mechanism of action of boric acid is unknown; generally cytotoxic to all cells. It is used in the treatment of yeast infections and cold sores.
NCI

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Propidium Iodide

A fluorescent nucleic acid dye which binds only to double-stranded nucleic acids. It has a molecular weight of 668.4, an absorbance maximum of 535nm, and an emission maximum of 617 nm. It is commonly used to determine the DNA content of a cell or to discriminate viable from non-viable cells.
NCI

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ergotismus

Poisoning caused by ingesting ergotized grain or by the misdirected or excessive use of ergot as a medicine.
MSH

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ektogeneze

Embryonic and fetal development that takes place in an artificial environment in vitro.
MSH

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úrazy – dispozice

Tendency toward involvement in accidents. Implies certain personality characteristics which predispose to accidents.
MSH

tendency toward involvement in accidents; implies certain personality or other characteristics which predispose to accidents.
CSP

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inventář nemocniční

Materials and equipment in stock; includes drugs in pharmacies, blood in blood banks, etc.
MSH

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plexus brachialis

The large network of nerve fibers which distributes the innervation of the upper extremity. The brachial plexus extends from the neck into the axilla. In humans, the nerves of the plexus usually originate from the lower cervical and the first thoracic spinal cord segments (C5-C8 and T1), but variations are not uncommon.
MSH

A network of nerves that sends signals from the spine to the arm and hand.
NCI

A nerve network originating from C5 to T1 that supplies cutaneous and muscular innervation to the arm and hand. (NCI)
NCI

a network of the nerves around the neck
CHV

A nerve network originating from C5 to T1 that supplies cutaneous and muscular innervation to the arm and hand.
NCI

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prostaglandinové endoperoxidy syntetické

Synthetic compounds that are analogs of the naturally occurring prostaglandin endoperoxides and that mimic their pharmacologic and physiologic activities. They are usually more stable than the naturally occurring compounds.
MSH

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prekursorové erytroidní buňky

The cells in the erythroid series derived from MYELOID PROGENITOR CELLS or from the bi-potential MEGAKARYOCYTE-ERYTHROID PROGENITOR CELLS which eventually give rise to mature RED BLOOD CELLS. The erythroid progenitor cells develop in two phases: erythroid burst-forming units (BFU-E) followed by erythroid colony-forming units (CFU-E); BFU-E differentiate into CFU-E on stimulation by ERYTHROPOIETIN, and then further differentiate into ERYTHROBLASTS when stimulated by other factors.
MSH

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výchova neprofesionální

Education and training outside of that for the professions.
MSH

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kyseliny octové

Acetic acid and its derivatives which may be formed by substitution reactions. Mono- and di-substituted, as well as halogenated compounds have been synthesized.
MSH

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ionty

An atom or group of atoms that have a positive or negative electric charge due to a gain (negative charge) or loss (positive charge) of one or more electrons. Atoms with a positive charge are known as CATIONS; those with a negative charge are ANIONS.
MSH

atom or radical having an electrical charge owing to the loss or gain of one or more electrons; substances that form ions are called electrolytes.
CSP

a charged particle
CHV

An atom or a molecule that has a positive or negative electrical charge. Examples are sodium, potassium, calcium, chloride, and phosphate. These ions help move nutrients into cells, help move waste out of cells, and help nerves, muscles, the heart, and the brain work the way they should.
NCI

An atom or molecule having a positive or negative charge owing to the loss or gain of one or more electrons.
NCI

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poloha plodu koncem pánevním

A malpresentation of the FETUS at near term or during OBSTETRIC LABOR with the fetal cephalic pole in the fundus of the UTERUS. There are three types of breech: the complete breech with flexed hips and knees; the incomplete breech with one or both hips partially or fully extended; the frank breech with flexed hips and extended knees.
MSH

A type of fetal presentation when the baby descends into the birth canal with hips, buttocks or its foot first during delivery.
NCI

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ochranné látky

Synthetic or natural substances which are given to prevent a disease or disorder or are used in the process of treating a disease or injury due to a poisonous agent.
MSH

A class of agents used in prophylactic or curative therapy to attenuate the negative side effects of toxins or drugs. Protective agents belong to various chemical classes, acting through various pharmacological mechanisms. They may neutralize exogenous poisons, coat mucosa for protection against physical or chemical damage, offer antioxidant protection against free radicals or ionizing radiation, or induce endogenous detoxifying enzymes. (NCI04)
NCI

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