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povidon

A polyvinyl polymer of variable molecular weight; used as suspending and dispersing agent and vehicle for pharmaceuticals; also used as blood volume expander.
MSH

synthetic polymer principally consisting of linear 1-vinyl-2-pyrrolidone groups; used as a dispersing and suspending agent and in pharmaceutical preparations.
CSP

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plíce – absces

Solitary or multiple collections of PUS within the lung parenchyma as a result of infection by bacteria, protozoa, or other agents.
MSH

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hubenost

A state of insufficient flesh on the body usually defined as having a body weight less than skeletal and physical standards. Depending on age, sex, and genetic background, a BODY MASS INDEX of less than 18.5 is considered as underweight.
MSH

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kontrolní skupiny

Groups that serve as a standard for comparison in experimental studies. They are similar in relevant characteristics to the experimental group but do not receive the experimental intervention.
MSH

In a clinical trial, the group that does not receive the new treatment being studied. This group is compared to the group that receives the new treatment, to see if the new treatment works.
NCI

A group used as a standard of comparison in a control experiment.
NCI

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GABA

The most common inhibitory neurotransmitter in the central nervous system.
MSH

a chemical substance released by nerves in the brain
CHV

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prednisolon

A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
MSH

synthetic glucocorticoid with the general properties of the corticosteroids.
CSP

A drug that lessens inflammation and suppresses the body`s immune response. It may also kill cancer cells. Prednisolone is used to treat disorders in many organ systems and to treat the symptoms of several types of leukemia and lymphoma. It is also being studied in the treatment of other types of cancer. Prednisolone is a type of therapeutic glucocorticoid.
NCI

A synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, prednisolone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cells populations. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=43296&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=43296&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C769″ NCI Thesaurus)
PDQ

A synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, prednisolone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cells populations. (NCI04)
NCI

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lymfatické uzliny

They are oval or bean shaped bodies (1 – 30 mm in diameter) located along the lymphatic system.
MSH

any of the accumulations of lymphoid tissue organized as definite lymphoid organs, varying from 1 to 25 mm in diameter situated along the course of lymphatic vessels and consisting of an outer cortical and an inner medullary part; the main source of lymphocytes of the peripheral blood and, as part of the reticuloendothelial system, serves as a defense mechanism by removing noxious agents, such as bacteria and toxins.
CSP

A rounded mass of lymphatic tissue that is surrounded by a capsule of connective tissue. Lymph nodes filter lymph (lymphatic fluid), and they store lymphocytes (white blood cells). They are located along lymphatic vessels.
NCI

A bean-shaped organ surrounded by a connective tissue capsule. It is part of the lymphatic system and is found throughout the body. It is composed predominantly of lymphocytes and its main function is immune protection. (NCI)
NCI

A bean-shaped organ surrounded by a connective tissue capsule. It is part of the lymphatic system and is found throughout the body. It is composed predominantly of lymphocytes and its main function is immune protection.
NCI

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thioxantheny

Compounds with three aromatic rings in linear arrangement with a SULFUR in the center ring.
MSH

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rohovka – nemoci

Diseases of the cornea.
MSH

pathological process affecting the transparent anterior portion of the fibrous coat of the eye.
CSP

Your cornea is the outermost layer of your eye. It is clear and shaped like a dome. The cornea helps to shield the rest of the eye from germs, dust, and other harmful matter. It also helps your eye to focus. If you wear contact lenses, they float on top of your corneas.

Problems with the cornea include

  • Refractive errors
  • Allergies
  • Infections
  • Injuries
  • Dystrophies – conditions in which parts of the cornea lose clarity due to a buildup of cloudy material

Treatments of corneal disorders include medicines, corneal transplantation and corneal laser surgery.

NIH National Eye Institute


MEDLINEPLUS

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galium – radioisotopy

Unstable isotopes of gallium that decay or disintegrate emitting radiation. Ga atoms with atomic weights 63-68, 70 and 72-76 are radioactive gallium isotopes.
MSH

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těhotenství – specifické beta-1-glykoproteiny

Glycoproteins with the electrophoretic mobility of BETA-GLOBULINS, secreted by the placental TROPHOBLASTS into the maternal bloodstream during PREGNANCY. They can be detected 18 days after OVULATION and reach 200 mg/ml at the end of pregnancy. They are associated with fetal well-being.
MSH

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androsteny

Unsaturated derivatives of the steroid androstane containing at least one double bond at any site in any of the rings.
MSH

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lymfomatoidní granulomatóza

An angiocentric and angiodestructive lymphoproliferative disorder primarily involving the lungs. It is caused by an Epstein-Barr virus-induced transformation of the B-cells, in a T-cell rich environment. Clinically and pathologically it resembles EXTRANODAL NK-T-CELL LYMPHOMA.
MSH

Destructive growth of lymph cells, usually involving the lungs, skin, kidneys, and central nervous system. Grades I and II are not considered cancerous, but grade III is considered a lymphoma.
NCI

An angiocentric and angiodestructive lymphoproliferative disease involving extranodal sites, comprised of Epstein-Barr virus (EBV)-positive B-cells admixed with reactive T-cells. Incidence is higher among adult males; patients with a history of immunodeficiency are at increased risk. The most common site of involvement is the lung; other common sites include brain, kidney, liver, and skin. Morphologically, three grades are recognized: grade I, II, and III. Grade III lymphomatoid granulomatosis should be approached clinically as a subtype of diffuse large B-cell lymphoma.
NCI

A neoplastic lymphoproliferative process characterized by an angiocentric arrangement of the tumor cells which is associated with angiodestruction. It includes lymphomatoid granulomatosis which is a lymphoproliferative lesion derived from mature B-lymphocytes and cases of extranodal NK/T-cell lymphomas of nasal type.
NCI

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thrombopoetin

A humoral factor that stimulates the production of thrombocytes (BLOOD PLATELETS). Thrombopoietin stimulates the proliferation of bone marrow MEGAKARYOCYTES and their release of blood platelets. The process is called THROMBOPOIESIS.
MSH

A substance made by the body that helps make blood cells, especially platelets. A form of TPO made in the laboratory is called recombinant human TPO and rHu TPO. TPO is being studied as a way to increase the number of platelets in cancer patients receiving chemotherapy.
NCI

a kind of hormone
CHV

Thrombopoietin is a lineage-restricted, glycoprotein growth factor ligand for the MPL receptor with selective action on megakaryopoiesis and platelet production. THPO has little direct effect on erythroid progenitor cells but may enhance erythropoiesis indirectly by preventing early erythroid progenitor cells from undergoing apoptotic cell death. (from OMIM 600044 and NCI)
NCI

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kortison

A naturally occurring glucocorticoid. It has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. Cortisone itself is inactive. It is converted in the liver to the active metabolite HYDROCORTISONE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p726)
MSH

naturally occurring glucocorticoid used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent; cortisone itself is inactive and is converted in the liver to the active metabolite cortisol.
CSP

A natural steroid hormone produced in the adrenal gland. It can also be made in the laboratory. Cortisone reduces swelling and can suppress immune responses.
NCI

A steroid hormone synthesized and secreted by the adrenal gland and necessary for life. It is involved with maintaining cardiovascular function, blood glucose balance, regulating the inflammatory response and metabolism of proteins, carbohydrates, and fat.
NCI

A corticosteroid with potent glucocorticoid activity. Therapeutic cortisone is the inactive precursor molecule of the active hormone cortisol, which is the hydroxylation product of cortisone by 11-beta-steroid dehydrogenase. Cortisol increases blood pressure and blood sugar levels, and suppresses the immune system, therefore cortisone is used to treat allergies or inflammation.
NCI

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gangliová stimulancia

Agents that mimic neural transmission by stimulation of the nicotinic receptors on postganglionic autonomic neurons. Drugs that indirectly augment ganglionic transmission by increasing the release or slowing the breakdown of acetylcholine or by non-nicotinic effects on postganglionic neurons are not included here nor are the nonspecific cholinergic agonists.
MSH

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předepisování léků

Directions written for the obtaining and use of DRUGS.
MSH

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anestézie inhalační

Anesthesia caused by the breathing of anesthetic gases or vapors or by insufflating anesthetic gases or vapors into the respiratory tract.
MSH

state characterized by loss of feeling or sensation caused by the breathing of anesthetic gases or vapors or by insufflating anesthetic gases or vapors into the respiratory tract.
CSP

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makrofágy – aktivace

The process of altering the morphology and functional activity of macrophages so that they become avidly phagocytic. It is initiated by lymphokines, such as the macrophage activation factor (MAF) and the macrophage migration-inhibitory factor (MMIF), immune complexes, C3b, and various peptides, polysaccharides, and immunologic adjuvants.
MSH

A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. [GOC:mgi_curators, ISBN:0781735149 “Fundamental Immunology”, PMID:14506301]
GO

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2,6-dichlorindofenol

A dye used as a reagent in the determination of vitamin C.
MSH

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Professional counsellor

A provider who is trained and educated in the performance of behavior health services through interpersonal communications and analysis. Training and education at the specialty level usually requires a master`s degree and clinical experience and supervision for licensure or certification. Sources: Abridged from definitions provided by the National Board of Certified Counselors and the American Association of Pastoral Counselors.


HL7V3.0

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gastritida hypertrofická

GASTRITIS with HYPERTROPHY of the GASTRIC MUCOSA. It is characterized by giant gastric folds, diminished acid secretion, excessive MUCUS secretion, and HYPOPROTEINEMIA. Symptoms include VOMITING; DIARRHEA; and WEIGHT LOSS.
MSH

Gastritis characterized by hypertrophy of the gastric mucosa with creation of giant gastric folds. It is associated with hypoalbuminemia due to albumin loss from the stomach. Signs and symptoms include nausea, vomiting, abdominal pain, edema, and weight loss.
NCI

A condition marked by inflammation and ulcers (breaks on the skin or on the surface of an organ) of the mucosa (inner lining) of the stomach and by overgrowth of the cells that make up the mucosa. Symptoms include vomiting, diarrhea, and weight loss. Patients with giant hypertrophic gastritis may be at a higher risk of stomach cancer.
NCI

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pro-opiomelanokortin

A 30-kDa protein synthesized primarily in the ANTERIOR PITUITARY GLAND and the HYPOTHALAMUS. It is also found in the skin and other peripheral tissues. Depending on species and tissues, POMC is cleaved by PROHORMONE CONVERTASES yielding various active peptides including ACTH; BETA-LIPOTROPIN; ENDORPHINS; MELANOCYTE-STIMULATING HORMONES; and others (GAMMA-LPH; CORTICOTROPIN-LIKE INTERMEDIATE LOBE PEPTIDE; N-terminal peptide of POMC or NPP).
MSH

precursor polypeptide from which ACTH, MSH, and beta-lipotropin are produced by posttranslational cleavage.
CSP

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Angiostrongylus

A genus of parasitic nematodes of the superfamily METASTRONGYLOIDEA. Two species, ANGIOSTRONGYLUS CANTONENSIS and A. vasorum, infest the lungs of rats and dogs, respectively. A. cantonensis is transmissible to man where it causes frequently fatal infection of the central nervous system.
MSH

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hlavní histokompatibilní komplex

The genetic region which contains the loci of genes which determine the structure of the serologically defined (SD) and lymphocyte-defined (LD) TRANSPLANTATION ANTIGENS, genes which control the structure of the IMMUNE RESPONSE-ASSOCIATED ANTIGENS, HUMAN; the IMMUNE RESPONSE GENES which control the ability of an animal to respond immunologically to antigenic stimuli, and genes which determine the structure and/or level of the first four components of complement.
MSH

genetic region found in all mammals whose products are primarily reponsible for the rapid rejection of grafts between individuals and which signal between lymphocytes and cells expressing antigen; H-2 in mouse and HLA in humans.
CSP

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kyselina 4-aminobenzoová

A member of the VITAMIN B COMPLEX. It used to be common in SUNSCREENING AGENTS until found to also be a sensitizer. The potassium salt is used therapeutically in fibrotic skin disorders.
MSH

An organic acid with UV absorption and antifibrotic properties. When exposed to light, aminobenzoic acid (para-aminobenzoic acid or PABA) absorbs UV light and emits excess energy via a photochemical reaction that may cause damage to DNA. Because DNA defects contribute to skin cancer, aminobenzoic acid is no longer widely used in sunscreen formulations. Aminobenzoic acid may also increase oxygen uptake at the tissue level and may enhance monoamine oxidase (MAO) activity to promote the degradation of serotonin, which in excess, may lead to fibrotic changes.
NCI

A nutrient in the vitamin B complex that the body needs in small amounts to function and stay healthy. Bacteria that live in the intestines need para-aminobenzoic acid to survive. Para-aminobenzoic acid is found in grains and foods from animals. It is being studied as a radiosensitizer (a substance that makes tumor cells more sensitive to radiation therapy) and in the treatment of certain skin disorders.
NCI

A nutrient in the vitamin B complex that the body needs in small amounts to function and stay healthy. Bacteria that live in the intestines need aminobenzoic acid to survive. Aminobenzoic acid is found in grains and foods from animals. It is being studied as a radiosensitizer (a substance that makes tumor cells more sensitive to radiation therapy) and in the treatment of certain skin disorders.
NCI

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kreatinkinasa – forma MM

An isoenzyme of creatine kinase found in the MUSCLE.
MSH

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role pohlaví

behavioral patterns expected from individuals by their social group believed to be typical of their sex; certain behavior patterns are culturally influenced, such as ascendance submissiveness, or occupational choices; sex role is often called psychosexual role.
CSP

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proestrus

A phase of the ESTROUS CYCLE that precedes ESTRUS. During proestrus, the Graafian follicles undergo maturation.
MSH

The estrous cycle phase in which there is heightened follicular activity. [GOC:dph, ISBN:0721662544 “Dorland`s Illustrated Medical Dictionary”]
GO

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zvířata divoká

Animals considered to be wild or feral or not adapted for domestic use. It does not include wild animals in zoos for which ANIMALS, ZOO is available.
MSH

animals considered to be wild or feral or not adapted for domestic use; prefer indexing specific animal, treed elsewhere, when possible.
CSP

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