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meningitida hemofilová

BACTERIAL INFECTIONS of the nervous system caused by HAEMOPHILUS organisms, and marked by prominent inflammation of the meninges. HAEMOPHILUS INFLUENZAE TYPE B is the most common causative organism. The condition primarily affects children under 6 years of age but may occur in adults. Clinical manifestations include fever; nuchal rigidity; PHOTOPHOBIA; SEIZURES; HEARING LOSS, SENSORINEURAL; COMA; and cerebrovascular thrombosis. The organism tends to enter the central nervous system following infections of adjacent structures, including the middle ear (see also OTITIS MEDIA), sinuses, and pharynx. (From Menkes, Textbook of Child Neurology, 5th ed, pp396-7)
MSH

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Golgiho aparát

A stack of flattened vesicles that functions in posttranslational processing and sorting of proteins, receiving them from the rough ENDOPLASMIC RETICULUM and directing them to secretory vesicles, LYSOSOMES, or the CELL MEMBRANE. The movement of proteins takes place by transfer vesicles that bud off from the rough endoplasmic reticulum or Golgi apparatus and fuse with the Golgi, lysosomes or cell membrane. (From Glick, Glossary of Biochemistry and Molecular Biology, 1990)
MSH

stack of flattened intracellular vesicles that functions in posttranslational processing and sorting of proteins, receiving them from the rough endoplasmic reticulum and directing them to secretory vesicles, lysosomes or the cell membrane; the movement of proteins takes place by transfer vesicles that bud off from the rough endoplasmic reticulum or Golgi apparatus.
CSP

A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions. [ISBN:0198506732 “Oxford Dictionary of Biochemistry and Molecular Biology”]
GO

A stack of flattened vesicles located between the nucleus and the secretory pole or surface of a cell. Functions in posttranslational processing and sorting of proteins, receiving them from the rough endoplasmic reticulum and directing them to secretory vesicles, lysosomes, or the cell membrane. The movement of proteins takes place by transfer vesicles that bud off from the rough endoplasmic reticulum or golgi apparatus and fuse with the golgi, lysosomes or cell membrane.
NCI

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EGTA

A chelating agent relatively more specific for calcium and less toxic than EDETIC ACID.
MSH

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salpingitida

Inflammation of the uterine salpinx, the trumpet-shaped FALLOPIAN TUBES, usually caused by ascending infections of organisms from the lower reproductive tract. Salpingitis can lead to tubal scarring, hydrosalpinx, tubal occlusion, INFERTILITY, and ectopic pregnancy (PREGNANCY, ECTOPIC)
MSH

inflammation of the fallopian tubes.
CSP

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bromthymolová modř

A pH sensitive dye that has been used as an indicator in many laboratory reactions.
MSH

A dye used as an indicator in determining pH. Bromthymol blue is a weak acid. It can be in acid or base form, depending on the pH of the solution. This reagent is yellow in acidic solutions, blue in basic solutions and green in neutral solution.
NCI

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viry onkogenní

Viruses that produce tumors.
MSH

viruses that produce tumors; see RTs for specific organisms.
CSP

A virus capable of transforming a cell to a malignant phenotype. (BioTech Life Science Dictionary)
NCI

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mefenytoin

An anticonvulsant effective in tonic-clonic epilepsy (EPILEPSY, TONIC-CLONIC). It may cause blood dyscrasias.
MSH

A heterocyclic organic compound with anticonvulsant property. Although the mechanism of action is not well established, mephenytoin potentially promotes sodium efflux from neurons in motor cortex, and stabilizes the threshold against hyperexcitability caused by excessive stimulation. Thus this agent reduces the membrane sodium gradient and prevents cortical seizure signal spreading. It may cause blood dyscrasias, therefore, this agent was only used after other less toxic anticonvulsants had failed.
NCI

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gramnegativní anaerobní baktérie

A large group of anaerobic bacteria which show up as pink (negative) when treated by the Gram-staining method.
MSH

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elektřina

The physical effects involving the presence of electric charges at rest and in motion.
MSH

A physical phenomenon associated with stationary or moving electrons and protons; energy made available by the flow of electric charge through a conductor.
NCI

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sarin

An organophosphorus ester compound that produces potent and irreversible inhibition of cholinesterase. It is toxic to the nervous system and is a chemical warfare agent.
MSH

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Brunnerovy žlázy

The abundant submucosal mucous glands in the DUODENUM. These glands secrete BICARBONATE IONS; GLYCOPROTEINS; and PEPSINOGEN II.
MSH

Small, flat, granular glands embedded in the submucous areolar tissue of the duodenum. (MeSH)
NCI

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opisthorchiáza

Infection with flukes of the genus Opisthorchis.
MSH

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mezonefros

One of a pair of excretory organs (mesonephroi) which grows caudally to the first pair (PRONEPHROI) during development. Mesonephroi are the permanent kidneys in adult amphibians and fish. In higher vertebrates, proneprhoi and most of mesonephroi degenerate with the appearance of metanephroi. The remaining ducts become WOLFFIAN DUCTS.
MSH

The middle one of the three pairs of embryonic renal organs developed in most vertebrates; its duct system is retained in the male as the epididymis and ductus deferens.
NCI

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Grenada

An island of the West Indies. Its capital is St. George`s. It was discovered in 1498 by Columbus who called it Concepcion. It was held at different times by the French and the British during the 18th century. The British suppressed a native uprising in 1795. It was an associate state of Great Britain 1967-74 but became an independent nation within the British Commonwealth in 1974. The original name referred to the Feast of the Immaculate Conception but it was later renamed for the Spanish kingdom of Granada. (From Webster`s New Geographical Dictionary, 1988, p467 & Room, Brewer`s Dictionary of Names, 1992, p219)
MSH

An island between the Caribbean Sea and Atlantic Ocean, north of Trinidad and Tobago. (NCI)
NCI

An island between the Caribbean Sea and Atlantic Ocean, north of Trinidad and Tobago. (CIA World Factbook 2002)
NCI

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elektroforéza v acetátové celulóze

Electrophoresis in which cellulose acetate is the diffusion medium.
MSH

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ESKIZOFRENIA, EDOZEIN MOTA

A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.
MSH

class of psychoses with disturbance mainly of cognition (content and form of thought, perception, sense of self versus external world, volition) and psychomotor function, rather than affect.
CSP

Schizophrenia is a severe, lifelong brain disorder. People who have it may hear voices, see things that aren`t there or believe that others are reading or controlling their minds. In men, symptoms usually start in the late teens and early 20s. They include hallucinations, or seeing things, and delusions such as hearing voices. For women, they start in the mid-20s to early 30s. Other symptoms include

  • Unusual thoughts or perceptions
  • Disorders of movement
  • Difficulty speaking and expressing emotion
  • Problems with attention, memory and organization

No one is sure what causes schizophrenia, but your genetic makeup and brain chemistry probably play a role. Medicines can relieve many of the symptoms, but it can take several tries before you find the right drug. You can reduce relapses by staying on your medicine for as long as your doctor recommends. With treatment, many people improve enough to lead satisfying lives.

NIH: National Institute of Mental Health


MEDLINEPLUS

A group of severe mental disorders in which a person has trouble telling the difference between real and unreal experiences, thinking logically, having normal emotional responses to others, and behaving normally in social situations. Symptoms include seeing, hearing, feeling things that are not there, having false ideas about what is taking place or who one is, nonsense speech, unusual behavior, lack of emotion, and social withdrawal.
NCI

A major psychotic disorder characterized by abnormalities in the perception or expression of reality. It affects the cognitive and psychomotor functions. Common clinical signs and symptoms include delusions, hallucinations, disorganized thinking, and retreat from reality.
NCI

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Bunyaviridae – infekce

Virus diseases caused by the BUNYAVIRIDAE.
MSH

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orbita – fraktury

Fractures of the bones in the orbit, which include parts of the frontal, ethmoidal, lacrimal, and sphenoid bones and the maxilla and zygoma.
MSH

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Metaproterenol Sulfate

The sulfate salt form of metaproterenol, a short-acting and selective sympathomimetic beta-receptor agonist with bronchodilator activity. Metaproterenol sulfate binds beta-2 adrenergic receptors in bronchial smooth muscle and stimulates intracellular adenyl cyclase, thereby increasing the production of cyclic adenosine monophosphate (cAMP). Increased cAMP levels cause relaxation of bronchial smooth muscle, improve mucocliary clearance and reduce inflammatory cell mediator release, especially from mast cells.
NCI

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guaninnukleotidy

phosphate ester of a guanine nucleoside, particularly the 5`-phosphate of guanine in N-glycosidic linkage with ribose or deoxyribose as occurs in nucleic acid.
CSP

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embolie vzduchová

Blocking of a blood vessel by air bubbles that enter the circulatory system, usually after TRAUMA; surgical procedures, or changes in atmospheric pressure.
MSH

embolism due to air bubbles entering the blood vessels after trauma, surgical procedures, or changes in atmospheric pressure.
CSP

The presence of bubbles of gas in the vascular system; occurrence is related to the entry of air into the venous circulation following trauma or surgery.
NCI

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scimitar syndrom

An anomalous pulmonary venous return in which the right PULMONARY VEIN is not connected to the LEFT ATRIUM but to the INFERIOR VENA CAVA. Scimitar syndrome is named for the crescent- or Turkish sword-like shadow in the chest radiography and is often associated with hypoplasia of the right lung and right pulmonary artery, and dextroposition of the heart.
MSH

A rare congenital cardiopulmonary defect characterized by abnormal right-sided pulmonary venous drainage and right lung malformations.
NCI

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hydroxyanisol butylovaný

Mixture of 2- and 3-tert-butyl-4-methoxyphenols that is used as an antioxidant in foods, cosmetics, and pharmaceuticals.
MSH

A white, waxy solid mixture of 2- and 3-Tert-butyl-4-hydroxyanisole with a faint aromatic odor. Butylated Hydroxyanisole is a widely used synthetic antioxidant in foods, cosmetics and pharmaceuticals mainly to preserve fats and oils. Butylated Hydroxyanisole is reasonably anticipated to be a human carcinogen. (NCI05)
NCI

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organoterapie

Historically, the treatment of disease by the administration of animal organs or their extracts (after Brown-Sequard). At present synthetic preparations substitute for the extracts of a gland. (From Stedman, 26th ed)
MSH

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methicilin

One of the PENICILLINS which is resistant to PENICILLINASE but susceptible to a penicillin-binding protein. It is inactivated by gastric acid so administered by injection.
MSH

semisynthetic penicillin used as an antibacterial in resistant staphylococcal infections.
CSP

A semisynthetic, narrow spectrum beta-lactamase-resistant penicillin antibiotic with bactericidal and beta-lactamase resistant activity. Methicillin binds to specific penicillin-binding proteins (BPBs) on the bacterial cell wall, thereby preventing the cross-linkage of peptidoglycans, which are critical components of the bacterial cell wall. This leads to an interruption of the bacterial cell wall and causes bacterial lysis.
NCI

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Gypsite

An pulverulent variety of gypsum.
MSH

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zaměstnanci – stížnosti

Formal procedures whereby the employee expresses any dissatisfaction or feeling of injustice regarding the work situation.
MSH

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mořské sasanky

The order Actiniaria, in the class ANTHOZOA, comprised of large, solitary polyps. All species are carnivorous.
MSH

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kalcifediol

The major circulating metabolite of VITAMIN D3. It is produced in the LIVER and is the best indicator of the body`s vitamin D stores. It is effective in the treatment of RICKETS and OSTEOMALACIA, both in azotemic and non-azotemic patients. Calcifediol also has mineralizing properties.
MSH

metabolic intermediate between cholecalciferol and 1,25- dihydroxycholecalciferol, with partial activity of latter.
CSP

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virus chřipky B

A negative-strand linear single-strand RNA virus with an 8 segment genome. Virions are enveloped and usually spherical or pleomorphic, 50-120 nm in diameter. Influenza B viruses are usually found only in humans. Unlike influenza A viruses, these viruses are not classified according to subtype.
NCI

Species of the genus INFLUENZAVIRUS B that cause HUMAN INFLUENZA and other diseases primarily in humans. Antigenic variation is less extensive than in type A viruses (INFLUENZA A VIRUS) and consequently there is no basis for distinct subtypes or variants. Epidemics are less likely than with INFLUENZA A VIRUS and there have been no pandemics. Previously only found in humans, Influenza B virus has been isolated from seals which may constitute the animal reservoir from which humans are exposed.
MSH

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