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hypernatriémie

Excessive amount of sodium in the blood. (Dorland, 27th ed)
MSH

excessive amount of sodium in the blood.
CSP

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podjazyková slinná žláza – nádory

Neoplasms of the sublingual glands.
MSH

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chlormethiazol

A sedative and anticonvulsant often used in the treatment of alcohol withdrawal. Chlormethiazole has also been proposed as a neuroprotective agent. The mechanism of its therapeutic activity is not entirely clear, but it does potentiate GAMMA-AMINOBUTYRIC ACID receptors response and it may also affect glycine receptors.
MSH

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Neurospora

genus of ascomycetous fungi, comprising bread molds; capable of converting tryptophan to nicotinic acid; used extensively in genetic and enzyme research.
CSP

A genus of ascomycetous fungi, family Sordariaceae, order SORDARIALES, comprising bread molds. They are capable of converting tryptophan to nicotinic acid and are used extensively in genetic and enzyme research. (Dorland, 27th ed)
MSH

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fosfor – radioisotopy

Unstable isotopes of phosphorus that decay or disintegrate emitting radiation. P atoms with atomic weights 28-34 except 31 are radioactive phosphorus isotopes.
MSH

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hypertriglyceridémie

A condition of elevated levels of TRIGLYCERIDES in the blood.
MSH

condition of elevated triglyceride concentration in the blood; an inherited form occurs in familial hyperlipoproteinemia IIb and hyperlipoproteinemia type IV; linked to higher risk of heart disease and arteriosclerosis.
CSP

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sacharosa

A nonreducing disaccharide composed of GLUCOSE and FRUCTOSE linked via their anomeric carbons. It is obtained commercially from SUGARCANE, sugar beet (BETA VULGARIS), and other plants and used extensively as a food and a sweetener.
MSH

nonreducing disaccharide, composed of glucose and fructose linked via their anomeric carbons.
CSP

A disaccharide consisting of glucose and fructose. The linkage is alpha with respect to the glucose and beta with respect to the fructose.
NCI

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chlorzoxazon

A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)
MSH

A benzoxazolone derivative with mild sedative and centrally-acting muscle relaxant activities. Although its exact mechanism of action is unknown, chlorzoxazone (CZ) appears to act at the spinal cord and subcortical levels of the brain to inhibit multisynaptic reflex arcs involved in producing and maintaining muscle spasms. This agent is extensively hydroxylated by cytochrome P450 2E1 (CYP2E1) to 6-hydroxychlorzoxazone (HCZ),11,12 which is subsequently glucuronidated and eliminated renally. Highly selective for CYP2E1, CZ may be used as a selective probe for phenotyping CYP2E1 in humans; the ratio of HCZ-to-CZ plasma concentrations obtained 2 to 4 hours after oral administration of CZ may be used as a phenotypic measure of CYP2E1 enzymatic activity.
NCI

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noviny

Publications printed and distributed daily, weekly, or at some other regular and usually short interval, containing news, articles of opinion (as editorials and letters), features, advertising, and announcements of current interest. (Webster`s 3d ed)
MSH

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fykokyanin

The metal-free blue phycobilin pigment in a conjugated chromoprotein of blue-green algae. It functions as light-absorbing substance together with chlorophylls.
MSH

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hypofosfatémie familiární

An inherited condition of abnormally low serum levels of PHOSPHATES (below 1 mg/liter) which can occur in a number of genetic diseases with defective reabsorption of inorganic phosphorus by the PROXIMAL RENAL TUBULES. This leads to phosphaturia, HYPOPHOSPHATEMIA, and disturbances of cellular and organ functions such as those in X-LINKED HYPOPHOSPHATEMIC RICKETS; OSTEOMALACIA; and FANCONI SYNDROME.
MSH

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sulfátadenylyltransferasa

An enzyme that catalyzes the activation of sulfate ions by ATP to form adenosine-5`-phosphosulfate and pyrophosphate. This reaction constitutes the first enzymatic step in sulfate utilization following the uptake of sulfate. EC 2.7.7.4.
MSH

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cholestáza

Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS).
MSH

intrahepatic impairment of bile flow; usually due to liver cell damage, but may be due to obstruction of intrahepatic bile ducts.
CSP

stoppage or suppression of bile by intrahepatic or extrahepatic causes.
CSP

Impairment of the bile flow caused by obstruction within the liver, or outside the liver in the bile duct system.
NCI

Any condition in which the release of bile from the liver is blocked. The blockage can occur in the liver (intrahepatic cholestasis) or in the bile ducts (extrahepatic cholestasis).
NCI

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nimorazol

An antitrichomonal agent which is effective either topically or orally and whose urinary metabolites are also trichomonicidal.
MSH

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physiopathological

Used with organs and diseases for disordered function in disease states.
MSH

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Disociační fuga

subtype of hysterical neurosis; the current classification is dissociative disorders; sudden temporary alterations in the normally integrative functions of consciousness.
CSP

A disorder characterized by sudden, unexpected travel away from one`s home or place of work accompanied by an inability to recall one`s past; the individual is confused about his or her personal identity and may assume a new identity.
NCI

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estery kyseliny sírové

Organic esters of sulfuric acid.
MSH

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chondroitinsulfáty

Derivatives of chondroitin which have a sulfate moiety esterified to the galactosamine moiety of chondroitin. Chondroitin sulfate A, or chondroitin 4-sulfate, and chondroitin sulfate C, or chondroitin 6-sulfate, have the sulfate esterified in the 4- and 6-positions, respectively. Chondroitin sulfate B (beta heparin; DERMATAN SULFATE) is a misnomer and this compound is not a true chondroitin sulfate.
MSH

A form contains glucuronic acid, B and C forms contain L-iduronic acid; all are sulfated on their galactosamine residues, B and C differing by the position of sulfation.
CSP

The major glycosaminoglycan (a type of sugar molecule) in cartilage.
NCI

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oxid dusičitý

Nitrogen oxide (NO2). A highly poisonous gas. Exposure produces inflammation of lungs that may only cause slight pain or pass unnoticed, but resulting edema several days later may cause death. (From Merck, 11th ed) It is a major atmospheric pollutant that is able to absorb UV light that does not reach the earth`s surface.
MSH

Found in the atmosphere as a key ingredient in photochemical formation of smog and acid rain, Nitrogen Dioxide is a poisonous gas that forms during combustion. Toxic at high concentrations, it reacts with moisture in the air to form nitric acid, highly corrosive and hazardous to plants and animals. (NCI04)
NCI

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pilotní projekty

Small-scale tests of methods and procedures to be used on a larger scale if the pilot study demonstrates that these methods and procedures can work.
MSH

The initial study examining a new method or treatment.
NCI

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imunoglobulin D

present on the membrane of many circulating B lymphocytes; may play a role in antigen triggered lymphocyte differentiation.
CSP

An immunoglobulin which accounts for less than 1% of plasma immunoglobulin. It is found on the membrane of many circulating B LYMPHOCYTES.
MSH

An immunoglobulin isotype (subclass). This isotype is expressed on naive B cells along with IgM. Little is known about its physiologic role.
NCI

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supratentoriální nádory

Primary and metastatic (secondary) tumors of the brain located above the tentorium cerebelli, a fold of dura mater separating the CEREBELLUM and BRAIN STEM from the cerebral hemispheres and DIENCEPHALON (i.e., THALAMUS and HYPOTHALAMUS and related structures). In adults, primary neoplasms tend to arise in the supratentorial compartment, whereas in children they occur more frequently in the infratentorial space. Clinical manifestations vary with the location of the lesion, but SEIZURES; APHASIA; HEMIANOPSIA; hemiparesis; and sensory deficits are relatively common features. Metastatic supratentorial neoplasms are frequently multiple at the time of presentation.
MSH

A benign or malignant neoplasm that occurs within the intracranial cavity above the tentorium cerebelli.
NCI

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chromafinní systém

The cells of the body which stain with chromium salts. They occur along the sympathetic nerves, in the adrenal gland, and in various other organs.
MSH

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nociceptory

Peripheral AFFERENT NEURONS which are sensitive to injuries or pain, usually caused by extreme thermal exposures, mechanical forces, or other noxious stimuli. Their cell bodies reside in the DORSAL ROOT GANGLIA. Their peripheral terminals (NERVE ENDINGS) innervate target tissues and transduce noxious stimuli via axons to the CENTRAL NERVOUS SYSTEM.
MSH

receptor for pain caused by damage to body tissue.
CSP

A free nerve ending that is a receptor for painful stimuli. (Kanner)
NCI

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hypofýza – přední lalok

The anterior glandular lobe of the pituitary gland, also known as the adenohypophysis. It secretes the ADENOHYPOPHYSEAL HORMONES that regulate vital functions such as GROWTH; METABOLISM; and REPRODUCTION.
MSH

The glandular or anterior lobe of the pituitary gland which secretes several hormones.
NCI

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napodobovací chování

The mimicking of the behavior of one individual by another.
MSH

mimicking a behavior of one individual by another.
CSP

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chirurgické nástroje

Hand-held tools or implements used by health professionals for the performance of surgical tasks.
MSH

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chromozomální poruchy

clinical conditions caused by an abnormal chromosome constitution in which there is extra or missing chromosome material, either a whole chromosome or a chromosome segment.
CSP

Clinical conditions caused by an abnormal chromosome constitution in which there is extra or missing chromosome material (either a whole chromosome or a chromosome segment). (from Thompson et al., Genetics in Medicine, 5th ed, p429)
MSH

A disorder that results from a chromosomal abnormality.
NCI

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normetanefrin

A methylated metabolite of norepinephrine that is excreted in the urine and found in certain tissues. It is a marker for tumors.
MSH

3-methylnorepinephrine, a metabolite of epinephrine excreted in urine.
CSP

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plankton

Community of tiny aquatic PLANTS and ANIMALS, and photosynthetic BACTERIA, that are either free-floating or suspended in the water, with little or no power of locomotion. They are divided into PHYTOPLANKTON and ZOOPLANKTON.
MSH

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