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lipoxygenasa

An enzyme of the oxidoreductase class primarily found in PLANTS. It catalyzes reactions between linoleate and other fatty acids and oxygen to form hydroperoxy-fatty acid derivatives.
MSH

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lišky

Any of several carnivores in the family CANIDAE, that possess erect ears and long bushy tails and are smaller than WOLVES. They are classified in several genera and found on all continents except Antarctica.
MSH

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chalony

Peptides that inhibit mitosis (ANTIMITOTICS). During the 1960`s the term referred to crude extracts that inhibited cell proliferation; the activity was later attributed to PYROGLUTAMATE type oligopeptides.
MSH

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syfilis kardiovaskulární

Cardiovascular manifestations of SYPHILIS, an infection of TREPONEMA PALLIDUM. In the late stage of syphilis, sometimes 20-30 years after the initial infection, damages are often seen in the blood vessels including the AORTA and the AORTIC VALVE. Clinical signs include syphilitic aortitis, aortic insufficiency, or aortic ANEURYSM.
MSH

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Pleomorphism

Having different forms at different stages of the life cycle.
NCI

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játra – regenerace

Repair or renewal of hepatic tissue.
MSH

renewal or physiological repair of damaged liver tissue.
CSP

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Freundovo adjuvans

An antigen solution emulsified in mineral oil. The complete form is made up of killed, dried mycobacteria, usually M. tuberculosis, suspended in the oil phase. It is effective in stimulating cell-mediated immunity (IMMUNITY, CELLULAR) and potentiates the production of certain IMMUNOGLOBULINS in some animals. The incomplete form does not contain mycobacteria.
MSH

antigen solution emulsified in mineral oil; the complete form is made up of killed, dried mycobacteria, usually Mycobacterium tuberculosis, suspended in the oil phase, effective in stimulating cell-mediated immunity and potentiating the production of immunoglobulins in some animals; the incomplete form does not contain mycobacteria.
CSP

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chemie farmaceutická

Chemistry dealing with the composition and preparation of agents having PHARMACOLOGIC ACTIONS or diagnostic use.
MSH

A chemistry-based discipline, also involving aspects of biological, medical and pharmaceutical sciences. It is concerned with the invention, discovery, design, identification and preparation of biologically active compounds, the study of their metabolism, the interpretation of their mode of action at the molecular level and the construction of structure-activity relationships. (Glossary of Terms Used in Medicinal Chemistry)
NCI

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Taenia

A genus of large tapeworms.
MSH

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pneumonie rickettsiální

Pneumonia caused by infection with bacteria of the family RICKETTSIACEAE.
MSH

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lorazepam

A benzodiazepine used as an anti-anxiety agent with few side effects. It also has hypnotic, anticonvulsant, and considerable sedative properties and has been proposed as a preanesthetic agent.
MSH

7-chloro-5-(2-chlorophenyl)-1, 3-dihydro-3-hydroxy-1,4- benzodiazepin-2-one.
CSP

a drug used to treat anxiety
CHV

A drug that is used to treat anxiety and certain seizure disorders (such as epilepsy), and to prevent nausea and vomiting caused by chemotherapy. It belongs to the families of drugs called antiemetics and benzodiazepines.
NCI

A benzodiazepine with anxiolytic, anti-anxiety, anticonvulsant, anti-emetic and sedative properties. Lorazepam enhances the effect of the inhibitory neurotransmitter gamma-aminobutyric acid on the GABA receptors by binding to a site that is distinct from the GABA binding site in the central nervous system. This leads to an increase in chloride channel opening events, a facilitation of chloride ion conductance, membrane hyperpolarization, and eventually inhibition of the transmission of nerve signals, thereby decreasing nervous excitation. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39757&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39757&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C619″ NCI Thesaurus)
PDQ

A benzodiazepine with anxiolytic, anti-anxiety, anticonvulsant, anti-emetic and sedative properties. Lorazepam enhances the effect of the inhibitory neurotransmitter gamma-aminobutyric acid on the GABA receptors by binding to a site that is distinct from the GABA binding site in the central nervous system. This leads to an increase in chloride channel opening events, a facilitation of chloride ion conductance, membrane hyperpolarization, and eventually inhibition of the transmission of nerve signals, thereby decreasing nervous excitation.
NCI

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fumaráty

Compounds based on fumaric acid.
MSH

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péče o dítě

Care of children in the home or institution.
MSH

care of children in the home or institution; for the raising of one`s own children or parenting use CHILD REARING
CSP

Children`s healthy development depends on safe and positive experiences when they are very young. If you work or go to school, you want to know that your child is in good hands while you are away. You may choose in-home care, where the caregiver comes to your home. Or your child might go to the caregiver`s home. Finally, there are child care centers. You need to choose the one that works for your family.

It is important to get to know your child`s caregivers. They will be a big part of your child`s life. The caregiver`s training should involve

  • Knowledge of how young children learn and grow
  • Positive, consistent discipline
  • Knowledge of the signs that a child is sick
  • Cleanliness and safety practices to help keep kids from getting sick or hurt
  • Basic first aid


MEDLINEPLUS

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tau-krystaliny

A type of crystallin that has been found in the lens (LENS, CRYSTALLINE) of certain species of VERTEBRATES. They are inactivated form of PHOSPHOPYRUVATE HYDRATASE.
MSH

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poliovirová vakcína orální

A live vaccine containing attenuated poliovirus, types I, II, and III, grown in monkey kidney cell tissue culture, used for routine immunization of children against polio. This vaccine induces long-lasting intestinal and humoral immunity. Killed vaccine induces only humoral immunity. Oral poliovirus vaccine should not be administered to immunocompromised individuals or their household contacts. (Dorland, 28th ed)
MSH

poliovirus vaccine, live, oral


HL7V3.0

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plíce – absces

Solitary or multiple collections of PUS within the lung parenchyma as a result of infection by bacteria, protozoa, or other agents.
MSH

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GABA

The most common inhibitory neurotransmitter in the central nervous system.
MSH

a chemical substance released by nerves in the brain
CHV

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Chironomidae

family of nonbiting midges, in the order Diptera; salivary glands of the genus Chironomus are used in studies of cellular genetics and biochemistry.
CSP

A family of nonbiting midges, in the order DIPTERA. Salivary glands of the genus Chironomus are used in studies of cellular genetics and biochemistry.
MSH

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telekomunikace

transmission of information over distances via electronic means.
CSP

Transmission of information over distances via electronic means. (MeSH)
NCI

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DNA-ligasy

Poly(deoxyribonucleotide):poly(deoxyribonucleotide)ligases. Enzymes that catalyze the joining of preformed deoxyribonucleotides in phosphodiester linkage during genetic processes during repair of a single-stranded break in duplex DNA. The class includes both EC 6.5.1.1 (ATP) and EC 6.5.1.2 (NAD).
MSH

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lymfatické uzliny

They are oval or bean shaped bodies (1 – 30 mm in diameter) located along the lymphatic system.
MSH

any of the accumulations of lymphoid tissue organized as definite lymphoid organs, varying from 1 to 25 mm in diameter situated along the course of lymphatic vessels and consisting of an outer cortical and an inner medullary part; the main source of lymphocytes of the peripheral blood and, as part of the reticuloendothelial system, serves as a defense mechanism by removing noxious agents, such as bacteria and toxins.
CSP

A rounded mass of lymphatic tissue that is surrounded by a capsule of connective tissue. Lymph nodes filter lymph (lymphatic fluid), and they store lymphocytes (white blood cells). They are located along lymphatic vessels.
NCI

A bean-shaped organ surrounded by a connective tissue capsule. It is part of the lymphatic system and is found throughout the body. It is composed predominantly of lymphocytes and its main function is immune protection. (NCI)
NCI

A bean-shaped organ surrounded by a connective tissue capsule. It is part of the lymphatic system and is found throughout the body. It is composed predominantly of lymphocytes and its main function is immune protection.
NCI

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galium – radioisotopy

Unstable isotopes of gallium that decay or disintegrate emitting radiation. Ga atoms with atomic weights 63-68, 70 and 72-76 are radioactive gallium isotopes.
MSH

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chlormethiazol

A sedative and anticonvulsant often used in the treatment of alcohol withdrawal. Chlormethiazole has also been proposed as a neuroprotective agent. The mechanism of its therapeutic activity is not entirely clear, but it does potentiate GAMMA-AMINOBUTYRIC ACID receptors response and it may also affect glycine receptors.
MSH

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tenosynovitida

Inflammation of the synovial lining of a tendon sheath. Causes include trauma, tendon stress, bacterial disease (gonorrhea, tuberculosis), rheumatic disease, and gout. Common sites are the hand, wrist, shoulder capsule, hip capsule, hamstring muscles, and Achilles tendon. The tendon sheaths become inflamed and painful, and accumulate fluid. Joint mobility is usually reduced.
MSH

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polynukleotidy

chain structure containing numerous nucleotides linked together by phosphodiester bonds (5`-3`); the nucleotide units consist of a purine or pyrimidine base, a pentose sugar, and a phosphate group.
CSP

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lymfomatoidní granulomatóza

An angiocentric and angiodestructive lymphoproliferative disorder primarily involving the lungs. It is caused by an Epstein-Barr virus-induced transformation of the B-cells, in a T-cell rich environment. Clinically and pathologically it resembles EXTRANODAL NK-T-CELL LYMPHOMA.
MSH

Destructive growth of lymph cells, usually involving the lungs, skin, kidneys, and central nervous system. Grades I and II are not considered cancerous, but grade III is considered a lymphoma.
NCI

An angiocentric and angiodestructive lymphoproliferative disease involving extranodal sites, comprised of Epstein-Barr virus (EBV)-positive B-cells admixed with reactive T-cells. Incidence is higher among adult males; patients with a history of immunodeficiency are at increased risk. The most common site of involvement is the lung; other common sites include brain, kidney, liver, and skin. Morphologically, three grades are recognized: grade I, II, and III. Grade III lymphomatoid granulomatosis should be approached clinically as a subtype of diffuse large B-cell lymphoma.
NCI

A neoplastic lymphoproliferative process characterized by an angiocentric arrangement of the tumor cells which is associated with angiodestruction. It includes lymphomatoid granulomatosis which is a lymphoproliferative lesion derived from mature B-lymphocytes and cases of extranodal NK/T-cell lymphomas of nasal type.
NCI

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gangliová stimulancia

Agents that mimic neural transmission by stimulation of the nicotinic receptors on postganglionic autonomic neurons. Drugs that indirectly augment ganglionic transmission by increasing the release or slowing the breakdown of acetylcholine or by non-nicotinic effects on postganglionic neurons are not included here nor are the nonspecific cholinergic agonists.
MSH

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chlorzoxazon

A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)
MSH

A benzoxazolone derivative with mild sedative and centrally-acting muscle relaxant activities. Although its exact mechanism of action is unknown, chlorzoxazone (CZ) appears to act at the spinal cord and subcortical levels of the brain to inhibit multisynaptic reflex arcs involved in producing and maintaining muscle spasms. This agent is extensively hydroxylated by cytochrome P450 2E1 (CYP2E1) to 6-hydroxychlorzoxazone (HCZ),11,12 which is subsequently glucuronidated and eliminated renally. Highly selective for CYP2E1, CZ may be used as a selective probe for phenotyping CYP2E1 in humans; the ratio of HCZ-to-CZ plasma concentrations obtained 2 to 4 hours after oral administration of CZ may be used as a phenotypic measure of CYP2E1 enzymatic activity.
NCI

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tetanový antitoxin

An antitoxin used for the treatment of TETANUS.
MSH

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Pongo pygmaeus

A species of orangutan, family HOMINIDAE, found in the forests on the island of Borneo.
MSH

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