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pseudomyxom peritonea

A condition characterized by poorly-circumscribed gelatinous masses filled with malignant mucin-secreting cells. Forty-five percent of pseudomyxomas arise from the ovary, usually in a mucinous cystadenocarcinoma (CYSTADENOCARCINOMA, MUCINOUS), which has prognostic significance. Pseudomyxoma peritonei must be differentiated from mucinous spillage into the peritoneum by a benign mucocele of the appendix. (Segen, Dictionary of Modern Medicine, 1992)
MSH

A build-up of mucus in the peritoneal cavity. The mucus may come from ruptured ovarian cysts, from the appendix, or from other abdominal tissues. Mucus-secreting cells may attach to the peritoneal lining and continue to secrete mucus.
NCI

A well differentiated mucinous adenocarcinoma of the peritoneum. The vast majority of cases represent tumor spread from a primary well differentiated mucinous adenocarcinoma of the appendix. Cases of pseudomyxoma peritonei associated with mucinous adenocarcinomas of the gallbladder, stomach, colon, rectum, pancreas, lung, breast, and fallopian tubes have also been reported. In the past, the ovary has been considered as a common primary site associated with pseudomyxoma peritonei. However, there is recent evidence based on immunohistochemistry and molecular genetic analysis suggesting that most cases of pseudomyxoma peritonei probably represent metastasis from an appendiceal and not ovarian primary. –2005
NCI

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mykobakteriofágy

Viruses whose host is one or more Mycobacterium species. They include both temperate and virulent types.
MSH

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histamin

An amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.
MSH

depressor amine derived by enzymatic decarboxylation of histidine, present in the secretory granules of mast cells; a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.
CSP

a chemical substance in the body that produces allergic reactions
CHV

A substance that has many effects in the body. It is released from some types of white blood cells during allergic reactions. It causes small blood vessels to dilate (widen) and become leaky, which can cause tissues to swell. It also causes smooth muscles to contract, gastric acid to be made, and the heart rate to increase. Histamine is used in tests for allergies, asthma, and gastric acid secretion. It is a type of neurotransmitter.
NCI

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spektinomycin

An antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of gonorrhea.
MSH

An aminocyclitol aminoglycoside antibiotic derived from Streptomyces spectabilis with bacteriostatic activity. Spectinomycin binds to the bacterial 30S ribosomal subunit. As a result, this agent interferes with the initiation of protein synthesis and with proper protein elongation. This eventually leads to bacterial cell death.
NCI

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Chlamydiales

An order of obligately intracellular, gram-negative bacteria that have the chlamydia-like developmental cycle of replication. This is a two-stage cycle that includes a metabolically inactive infectious form, and a vegetative form that replicates by binary fission. Members of Chlamydiales are disseminated by aerosol or by contact. There are at least six recognized families: CHLAMYDIACEAE, Criblamydiaceae, Parachlamydiaceae, Rhabdochlamydia, Simkaniaceae, and Waddliaceae.
MSH

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psychologická teorie

Principles applied to the analysis and explanation of psychological or behavioral phenomena.
MSH

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myelitida z příčné léze

Inflammation of a transverse portion of the spinal cord characterized by acute or subacute segmental demyelination or necrosis. The condition may occur sporadically, follow an infection or vaccination, or present as a paraneoplastic syndrome (see also ENCEPHALOMYELITIS, ACUTE DISSEMINATED). Clinical manifestations include motor weakness, sensory loss, and incontinence. (Adams et al., Principles of Neurology, 6th ed, pp1242-6)
MSH

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Histone H4

Histone H4 is a core subunit of the eukaryotic nucleosome complex. Histones are basic nuclear proteins responsible for the nucleosome structure of chromatin. Repeating nucleosome units contain two molecules each of Histones H2A, H2B, H3, and H4 that form an octamer complex around which approximately 146 base pairs of DNA is wrapped. The nucleosome interacts with DNA between nucleosome units in mediating chromatin compaction into higher order structures. (Entrez Gene)
NCI

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mitochondriální ADP/ATP-translokasy

A class of nucleotide translocases found abundantly in mitochondria that function as integral components of the inner mitochondrial membrane. They facilitate the exchange of ADP and ATP between the cytosol and the mitochondria, thereby linking the subcellular compartments of ATP production to those of ATP utilization.
MSH

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fenylsulfonan chlorortuťnatý

A cytotoxic sulfhydryl reagent that inhibits several subcellular metabolic systems and is used as a tool in cellular physiology.
MSH

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psychoterapie krátká

Any form of psychotherapy designed to produce therapeutic change within a minimal amount of time, generally not more than 20 sessions.
MSH

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myosin – těžké řetězce

The larger subunits of MYOSINS. The heavy chains have a molecular weight of about 230 kDa and each heavy chain is usually associated with a dissimilar pair of MYOSIN LIGHT CHAINS.
MSH

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HLA-B8 antigen

A specific HLA-B surface antigen subtype. Members of this subtype contain alpha chains that are encoded by the HLA-B*08 allele family.
MSH

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sodíko-draslíková ATPasa

An enzyme that catalyzes the active transport system of sodium and potassium ions across the cell wall. Sodium and potassium ions are closely coupled with membrane ATPase which undergoes phosphorylation and dephosphorylation, thereby providing energy for transport of these ions against concentration gradients.
MSH

family of ouabain-sensitive, ATP-driven, transmembrane molecular pumps which maintain opposing concentration gradients of sodium and potassium across cell membranes term not valid for FY 92.
CSP

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cholekalciferol

Derivative of 7-dehydroxycholesterol formed by ULTRAVIOLET RAYS breaking of the C9-C10 bond. It differs from ERGOCALCIFEROL in having a single bond between C22 and C23 and lacking a methyl group at C24.
MSH

produced in human and other animal tissue by photoactivation (normally sunlight on skin) of 7-dehydrocholesterol.
CSP

A steroid hormone produced in the skin when exposed to ultraviolet light or obtained from dietary sources. The active form of cholecalciferol, 1,25-dihydroxycholecalciferol (calcitriol) plays an important role in maintaining blood calcium and phosphorus levels and mineralization of bone. The activated form of cholecalciferol binds to vitamin D receptors and modulates gene expression. This leads to an increase in serum calcium concentrations by increasing intestinal absorption of phosphorus and calcium, promoting distal renal tubular reabsorption of calcium and increasing osteoclastic resorption.
NCI

Vitamin D synthesized from ergosterol in yeast and plants.
NCI

A nutrient that the body needs in small amounts to function and stay healthy. Cholecalciferol helps the body use calcium and phosphorus to make strong bones and teeth. It is fat-soluble (can dissolve in fats and oils) and is found in fatty fish, egg yolks, and dairy products. Skin exposed to sunshine can also make cholecalciferol. Not enough cholecalciferol can cause a bone disease called rickets. It is being studied in the prevention and treatment of some types of cancer.
NCI

A steroid hormone produced in the skin when exposed to ultraviolet light or obtained from dietary sources. The active form of cholecalciferol, 1,25-dihydroxycholecalciferol (calcitriol) plays an important role in maintaining blood calcium and phosphorus levels and mineralization of bone. The activated form of cholecalciferol binds to vitamin D receptors and modulates gene expression. This leads to an increase in serum calcium concentrations by increasing intestinal absorption of phosphorus and calcium, promoting distal renal tubular reabsorption of calcium and increasing osteoclastic resorption. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39734&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39734&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C48194″ NCI Thesaurus)
PDQ

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puerperální infekce

An infection occurring in PUERPERIUM, the period of 6-8 weeks after giving birth.
MSH

infection occurring in the puerperium or postpartum period.
CSP

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ipratropium

A muscarinic antagonist structurally related to ATROPINE but often considered safer and more effective for inhalation use. It is used for various bronchial disorders, in rhinitis, and as an antiarrhythmic.
MSH

A synthetic derivative of the alkaloid atropine with anticholinergic properties. Ipratropium antagonizes the actions of acetylcholine at parasympathetic postganglionic effector cell junctions. When inhaled, ipratropium binds competitively to cholinergic receptors in the bronchial smooth muscle thereby blocking the bronchoconstrictor actions of the acetylcholine (Ach) mediated vagal impulses. Inhibition of the vagal tone leads to dilation of the large central airways resulting in bronchodilation.
NCI

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Holtzmanův test inkoustové skvrny

Personality evaluation based on the scoring of several variables as a result of the subject`s responses in perceiving 47 inkblot plates.
MSH

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aplikace sublingvální

Administration of a soluble dosage form by placement under the tongue.
MSH

Sublingual


HL7V3.0

Administration beneath the tongue. (FDA)
NCI

Administration of a drug beneath the tongue. The route provides rapid absorption, the drug immediately enters the bloodstream without first passing through the intestinal wall and liver. However, most drugs cannot be taken this way because they may be absorbed incompletely or erratically.
NCI

Sublingual


HL7V3.0

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cholesteroloxidasa

An enzyme that catalyzes the oxidation of cholesterol in the presence of molecular oxygen to 4-cholesten-3-one and hydrogen peroxide. The enzyme is not specific for cholesterol, but will also oxidize other 3-hydroxysteroids. EC 1.1.3.6.
MSH

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pulpotomie

Surgical amputation of the coronal portion of the dental pulp. (Journal of Prosthetic Dentistry Vol. 81 No. 1, page 94)
NCI

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kyselina nalidixová

A synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA GYRASE.
MSH

A synthetic quinolone and antibacterial agent with urinary tract antiseptic activity. Nalidixic acid concentrates in the renal tubules and bladder and exerts its local antibacterial actions by interference of DNA gyrase activity, thereby inhibiting DNA synthesis during bacterial replication in a dose-dependent manner. Nalidixic acid is active against most gram-negative organisms that cause urinary tract infections.
NCI

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Xiphosura

An arthropod subclass (Xiphosura) comprising the North American (Limulus) and Asiatic (Tachypleus) genera of horseshoe crabs.
MSH

only living member of the class Malacostraca; not a true crab; body has a broadly oval shell and a long slender tail; lives in a marine environment.
CSP

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alfa-1-adrenergní receptory

A subclass of alpha-adrenergic receptors that mediate contraction of SMOOTH MUSCLE in a variety of tissues such as ARTERIOLES; VEINS; and the UTERUS. They are usually found on postsynaptic membranes and signal through GQ-G11 G-PROTEINS.
MSH

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chorioadenom

A uterine tumor derived from persistent gestational TROPHOBLASTS, most likely after a molar pregnancy (HYDATIDIFORM MOLE). Invasive hyadatiform mole develops in about 15% of patients after evacuation of a complete mole and less frequently after other types of gestation. It may perforate the MYOMETRIUM and erode uterine vessels causing hemorrhage.
MSH

A type of cancer that grows into the muscular wall of the uterus. It is formed after conception (fertilization of an egg by a sperm). It may spread to other parts of the body, such as the vagina, vulva, and lung.
NCI

This term is used when a complete mole or very rarely a partial mole invades the myometrium. Microscopically, villi of hydatidiform mole are present within the myometrium or the myometrial vessels. Patients have persistent or rising hCG levels.
NCI

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PUVA terapie

Photochemotherapy using a psoralen compound as the photosensitizing agent and ultraviolet light type A (UVA).
MSH

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nos – obstrukce

Any hindrance to the passage of air into and out of the nose. The obstruction may be unilateral or bilateral, and may involve any part of the NASAL CAVITY.
MSH

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nemocnice vojenské

Hospitals which provide care for the military personnel and usually for their dependents.
MSH

A health care facility operated by the Department of Defense.


HL7V3.0

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afektivní symptomy

Mood or emotional responses dissonant with or inappropriate to the behavior and/or stimulus.
MSH

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chromatografie plynová

Fractionation of a vaporized sample as a consequence of partition between a mobile gaseous phase and a stationary phase held in a column. Two types are gas-solid chromatography, where the fixed phase is a solid, and gas-liquid, in which the stationary phase is a nonvolatile liquid supported on an inert solid matrix.
MSH

technique for separating gas mixtures in which the gas is passed through a long column containing a fixed absorbent phase that separates the gas mixture into its component parts.
CSP

A chromatographic technique in which the stationary phase is solid while the mobile phase is gaseous samples. The gaseous samples are separated based on their different adsorption ability to the solid phase.
NCI

Chromatography, Gas


HL7V3.0

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