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chinazoliny

two ring heterocyclic compound.
CSP

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vápníkové kanály

Voltage-dependent cell membrane glycoproteins selectively permeable to calcium ions. They are categorized as L-, T-, N-, P-, Q-, and R-types based on the activation and inactivation kinetics, ion specificity, and sensitivity to drugs and toxins. The L- and T-types are present throughout the cardiovascular and central nervous systems and the N-, P-, Q-, & R-types are located in neuronal tissue.
MSH

voltage-dependent cell membrane glycoproteins selectively permeable to calcium ions.
CSP

An ion channel with selective permeability to calcium.
NCI

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1-propanol

A colorless liquid made by oxidation of aliphatic hydrocarbons that is used as a solvent and chemical intermediate.
MSH

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karotická endarterektomie

The excision of the thickened, atheromatous tunica intima of a carotid artery.
MSH

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Indiana

A state in the north central United States. Its capital is Indianapolis.
NCI

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aspects of radiation effects

Used for effects of ionizing and nonionizing radiation upon living organisms, organs and tissues, and their constituents, and upon physiologic processes. It includes the effect of irradiation on drugs and chemicals.
MSH

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kostní svalek

The bony deposit formed between and around the broken ends of BONE FRACTURES during normal healing.
MSH

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algoritmy

A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task.
MSH

A defined procedure for solving a problem. Applied to a problem-solving procedure implemented in software to be executed by a computer.
NCI

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endoplazmatické retikulum

A system of cisternae in the CYTOPLASM of many cells. In places the endoplasmic reticulum is continuous with the plasma membrane (CELL MEMBRANE) or outer membrane of the nuclear envelope. If the outer surfaces of the endoplasmic reticulum membranes are coated with ribosomes, the endoplasmic reticulum is said to be rough-surfaced (ENDOPLASMIC RETICULUM, ROUGH); otherwise it is said to be smooth-surfaced (ENDOPLASMIC RETICULUM, SMOOTH). (King & Stansfield, A Dictionary of Genetics, 4th ed)
MSH

system of cisternae in the cytoplasm of many cells; in places the endoplasmic reticulum is continuous with the plasma membrane or outer membrane of the nuclear envelope; rough endoplasmic reticulum membranes are coated with ribosomes and are involved in protein synthesis and transport; smooth endoplasmic reticulum is involved in steroid synthesis.
CSP

The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). [ISBN:0198506732 “Oxford Dictionary of Biochemistry and Molecular Biology”]
GO

a part of the cell structure
CHV

The endoplasmic reticulum is a network of tubular membranes within the cytoplasm of the cell, occurring either with a smooth surface (smooth endoplasmic reticulum) or studded with ribosomes (rough endoplasmic reticulum), involved in the transport of materials. (Infoplease Dictionary)
NCI

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kojenecká mortalita

Postnatal deaths from BIRTH to 365 days after birth in a given population. Postneonatal mortality represents deaths between 28 days and 365 days after birth (as defined by National Center for Health Statistics). Neonatal mortality represents deaths from birth to 27 days after birth.
MSH

all human infant deaths reported in a given population; statistically reported.
CSP

Any disease or condition resulting in postnatal death before age 1 yr. (NCI)
NCI

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rentgendiagnostika – dvourozměrná projekce

A method of producing a high-quality scan by digitizing and subtracting the images produced by high- and low-energy x-rays.
MSH

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kandidóza

Infection with a fungus of the genus CANDIDA. It is usually a superficial infection of the moist areas of the body and is generally caused by CANDIDA ALBICANS. (Dorland, 27th ed)
MSH

infection with a fungus of the genus Candida; usually a superficial infection of the moist areas of the body and is generally caused by Candida albicans; includes chronic mucocutaneous candidiasis, cutaneous candidiasis, oral candidiasis (thrush), and monilial vaginitis.
CSP

A condition in which Candida albicans, a type of yeast, grows out of control in moist skin areas of the body. It is usually a result of a weakened immune system, but can be a side effect of chemotherapy or treatment with antibiotics. Thrush usually affects the mouth (oral thrush); however, rarely, it spreads throughout the entire body.
NCI

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slitiny

A mixture of metallic elements or compounds with other metallic or metalloid elements in varying proportions.
MSH

mixture of two or more metals or of one or more metals with certain metalloids that are mutually soluble in the molten condition; distinguished as binary, ternary, quaternary, etc., depending on the number of metals in the mixture.
CSP

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koronavirus krocanů

A species of CORONAVIRUS causing enteritis in turkeys and pullets.
MSH

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informace – šíření

The circulation or wide dispersal of information.
MSH

circulation or wide dispersal of information.
CSP

For information to be useful, not only does it need to be made available at the right time to those who need it such as policy makers, program planners, and health professionals, and patients but it has to be in the right form. Information Dissemination includes both research into means of information distribution and the actual distribution of information.
NCI

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vztek

Fury; violent, intense anger.
MSH

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kapsida

The outer protein protective shell of a virus, which protects the viral nucleic acid.
MSH

protein shell which surrounds the virus nucleic acid; has icosahedral, helical, or complex symmetry.
CSP

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talasémie alfa

A disorder characterized by reduced synthesis of the alpha chains of hemoglobin. The severity of this condition can vary from mild anemia to death, depending on the number of genes deleted.
MSH

A genetic hematologic disorder characterized by partial or complete absence of the alpha globin chains of the heme molecule.
NCI

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enzymy – aktivace

Conversion of an inactive form of an enzyme to one possessing metabolic activity. It includes 1, activation by ions (activators); 2, activation by cofactors (coenzymes); and 3, conversion of an enzyme precursor (proenzyme or zymogen) to an active enzyme.
MSH

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injekce subkutánní

Forceful administration under the skin of liquid medication, nutrient, or other fluid through a hollow needle piercing the skin.
MSH

Injection, subcutaneous


HL7V3.0

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potkani – mutantní kmeny

Rats bearing mutant genes which are phenotypically expressed in the animals.
MSH

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uhlík – isotopy

Stable carbon atoms that have the same atomic number as the element carbon, but differ in atomic weight. C-13 is a stable carbon isotope.
MSH

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Ambenonium

A bisquaternary ammonium alcohol with parasympathomimetic activity. The positive charge of ambenonium allows it to act as an acetylcholinesterase inhibitor by binding to the anionic site at the reactive center of acetylcholinesterase, preventing the breakdown of acetylcholine and producing an indirect cholinomimetic effect at both nicotinic and muscarinic receptors. Ambenonium also has direct agonist activity at nicotinic receptors, potentiating the cholinomimetic effect at the neuromuscular junction.
NCI

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inseminace umělá

Artificial introduction of SEMEN or SPERMATOZOA into the VAGINA to facilitate FERTILIZATION.
MSH

Introduction of sperm into the female reproductive tract by artificial means in order to achieve fertilization.
NCI

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receptory cholecystokininu

Cell surface proteins that bind cholecystokinin (CCK) with high affinity and trigger intracellular changes influencing the behavior of cells. Cholecystokinin receptors are activated by GASTRIN as well as by CCK-4; CCK-8; and CCK-33. Activation of these receptors evokes secretion of AMYLASE by pancreatic acinar cells, acid and PEPSIN by stomach mucosal cells, and contraction of the PYLORUS and GALLBLADDER. The role of the widespread CCK receptors in the central nervous system is not well understood.
MSH

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karcinom

A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm but is often wrongly used as a synonym for “cancer.” (From Dorland, 27th ed)
MSH

malignant new growth arising from epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases.
CSP

Cancer that begins in the skin or in tissues that line or cover internal organs.
NCI

type of cancer
CHV

A malignant tumor arising from epithelial cells. Carcinomas that arise from glandular epithelium are called adenocarcinomas, those that arise from squamous epithelium are called squamous cell carcinomas, and those that arise from transitional epithelium are called transitional cell carcinomas. Morphologically, the malignant epithelial cells may display abnormal mitotic figures, anaplasia, and necrosis. Carcinomas are graded by the degree of cellular differentiation as well, moderately, or poorly differentiated. Carcinomas invade the surrounding tissues and tend to metastasize to other anatomic sites. Lung carcinoma, skin carcinoma, breast carcinoma, colon carcinoma, and prostate carcinoma are the most frequently seen carcinomas.
NCI

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amidy

Organic compounds containing the -CO-NH2 radical. Amides are derived from acids by replacement of -OH by -NH2 or from ammonia by the replacement of H by an acyl group. (From Grant & Hackh`s Chemical Dictionary, 5th ed)
MSH

organic compound derived from ammonia by substituting an acyl radical for hydrogen, or from an acid by replacing the OH group by NH2.
CSP

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pojistná škoda – hlášení

The design, completion, and filing of forms with the insurer.
MSH

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receptory muskarinové

One of the two major classes of cholinergic receptors. Muscarinic receptors were originally defined by their preference for MUSCARINE over NICOTINE. There are several subtypes (usually M1, M2, M3….) that are characterized by their cellular actions, pharmacology, and molecular biology.
MSH

G protein coupled surface receptor that mediates acetylcholine action on smooth and cardiac muscle and in CNS; may be linked to a potassium channel (membrane polarization) or second messenger systems.
CSP

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kardiostimulace umělá

Regulation of the rate of contraction of the heart muscles by an artificial pacemaker.
MSH

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