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fenoxybenzamin

An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.
MSH

A synthetic, dibenzamine alpha adrenergic antagonist with antihypertensive and vasodilatory properties. Phenoxybenzamine non-selectively and irreversibly blocks the postsynaptic alpha-adrenergic receptor in smooth muscle, thereby preventing vasoconstriction, relieving vasospasms, and decreasing peripheral resistance. Reflex tachycardia may occur and may be enhanced by blockade of alpha-2 receptors which enhances norepinephrine release. Phenoxybenzamine is reasonably anticipated to be a human carcinogen.
NCI

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pojistná škoda – hlášení

The design, completion, and filing of forms with the insurer.
MSH

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eosin

A versatile red dye used in cosmetics, pharmaceuticals, textiles, etc., and as tissue stain, vital stain, and counterstain with HEMATOXYLIN. It is also used in special culture media.
MSH

Dye and chemical solution stains for medical purposes are mixtures of synthetic or natural dyes or nondye chemicals in solutions used in staining cells and tissues for diagnostic histopathology, cytopathology, or hematology.
SPN

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Connecticut

A state in the northeastern United States. Its capital is Hartford.
NCI

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stomatologické nemoci

General or unspecified diseases of the stomatognathic system, comprising the mouth, teeth, jaws, and pharynx.
MSH

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filadelfský chromozóm

An aberrant form of human CHROMOSOME 22 characterized by translocation of the distal end of chromosome 9 from 9q34, to the long arm of chromosome 22 at 22q11. It is present in the bone marrow cells of 80 to 90 per cent of patients with chronic myelocytic leukemia (LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE).
MSH

An abnormality of chromosome 22 in which part of chromosome 9 is transferred to it. Bone marrow cells that contain the Philadelphia chromosome are often found in chronic myelogenous leukemia.
NCI

A translocation between chromosomes 9 and 22. It is the hallmark for chronic myelogenous leukemia (CML).
NCI

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Interferon Alfa-2b

A non-glycosylated recombinant interferon with antiviral and antineoplastic activities. Alfa interferons bind to specific cell-surface receptors, resulting in the transcription and translation of genes whose protein products mediate antiviral, antiproliferative, anticancer, and immune-modulating effects. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=462279&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=462279&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1953″ NCI Thesaurus)
PDQ

A non-glycosylated recombinant interferon alpha, subtype 2b, used as an antiviral and antineoplastic agent. Alpha interferons bind to specific cell-surface receptors, resulting in the transcription and translation of genes whose protein products mediate antiviral, antiproliferative, anticancer, and immune-modulating effects. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=448847&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=448847&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1953″ NCI Thesaurus)
PDQ

A drug used to treat some infections caused by viruses and several types of cancer. These include hairy cell leukemia, melanoma, and follicular lymphoma. It is a form of interferon alfa (a substance normally made by cells of the immune system) that is made in the laboratory. It is a type of biological response modifier.
NCI

A non-glycosylated recombinant interferon with antiviral and antineoplastic activities. Alfa interferons bind to specific cell-surface receptors, resulting in the transcription and translation of genes whose protein products mediate antiviral, antiproliferative, anticancer, and immune-modulating effects.
NCI

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epilepsie tonicko-klonická

A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process). (From Adams et al., Principles of Neurology, 6th ed, p329)
MSH

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sexuální chování – antikoncepce

Behavior patterns of those practicing CONTRACEPTION.
MSH

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stres mechanický

A purely physical condition which exists within any material because of strain or deformation by external forces or by non-uniform thermal expansion; expressed quantitatively in units of force per unit area.
MSH

physical condition which exists within any material because of strain or deformation by external forces or by non-uniform thermal expansion.
CSP

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fosfátacetyltransferasa

An enzyme that catalyzes the synthesis of acetylphosphate from acetyl-CoA and inorganic phosphate. Acetylphosphate serves as a high-energy phosphate compound. EC 2.3.1.8.
MSH

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interneurony

Most generally any neurons which are not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions.
MSH

generally neurons which are not motor or sensory; may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions.
CSP

A general term for any neurons which are not motor or sensory. Interneuron may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions. (from MeSH)
NCI

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herpesvirus 1 koní

A species of VARICELLOVIRUS causing abortion and respiratory disease in horses.
MSH

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Coombsův test

Hemagglutination test in which Coombs` reagent (antiglobulin, or anti-human globulin rabbit immune serum) is added to detect incomplete (non-agglutinating, univalent, blocking) antibodies coating erythrocytes. The direct test is applied to red cells which have been coated with antibody in vivo (e.g., in hemolytic disease of newborn, autoimmune hemolytic anemia, and transfusion reactions). The indirect test is applied to serum to detect the presence of antibody (e.g., in detection of incompatibility in cross-matching tests, detection and identification of irregular antibodies, and in detection of antibodies not identifiable by other means).
MSH

A laboratory test to identify antibodies that can bind to the surface of red blood cells or platelets and destroy them. This test is used to diagnose certain blood disorders in which patients make antibodies to their own red blood cells or platelets. It is also used to determine blood type.
NCI

Hemagglutination test in which Coombs` reagent (antiglobulin, or anti-human globulin rabbit immune serum) is added to detect incomplete (non-agglutinating, univalent, blocking) antibodies coating erythrocytes. The direct test is applied to red cells which have been coated with antibody in vivo (e.g., in hemolytic disease of newborn, autoimmune hemolytic anemia, and transfusion reactions). The indirect test is applied to serum to detect the presence of antibody (e.g., in detection of incompatibility in cross-matching tests, detection and identification of irregular antibodies, and in detection of antibodies not identifiable by other means). (MeSH)
NCI

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Sturgeův-Weberův syndrom

A non-inherited congenital condition with vascular and neurological abnormalities. It is characterized by facial vascular nevi (PORT-WINE STAIN), and capillary angiomatosis of intracranial membranes (MENINGES; CHOROID). Neurological features include EPILEPSY; cognitive deficits; GLAUCOMA; and visual defects.
MSH

A rare, congenital disorder that affects the brain, skin, and eyes. Abnormal blood vessel growth occurs in the trigeminal nerve in the face and the meninges (covering) of the brain. This abnormal growth causes red or purple skin discoloration (sometimes called a port wine stain), usually on one side of the face, and can also cause seizures, learning disabilities, and glaucoma.
NCI

A congenital disorder characterized by the presence of a port-wine nevus birthmark on one or both sides of the face. Additional clinical manifestations may include seizures, leptomenigeal angiomas, glaucoma, progressive hemiparesis and cognitive deficits.
NCI

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fosfolipasy

A class of enzymes that catalyze the hydrolysis of phosphoglycerides or glycerophosphatidates. EC 3.1.-.
MSH

Enzymes that catalyze the cleavage of a phospholipid molecule by the addition of water, thereby causing hydrolysis. The classification is based on the specificity of the bond cleaved. Hydrolytic activity initiates signaling cascades in the cell.
NCI

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geny intracisternální A-částicové

Genes of IAP elements (a family of retrovirus-like genetic elements) which code for virus-like particles (IAPs) found regularly in rodent early embryos. (“Intracisternal” refers to the cisternae of the endoplasmic reticulum.) Under certain circumstances, such as DNA hypomethylation they are transcribed. Their transcripts are found in a variety of neoplasms, including plasmacytomas, neuroblastoma, rhabdomyosarcomas, teratocarcinomas, and colon carcinomas.
MSH

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erythema induratum

A type of panniculitis characterized histologically by the presence of granulomas, vasculitis, and necrosis. It is traditionally considered to be the tuberculous counterpart of nodular vasculitis, but is now known to occur without tuberculous precedent. It is seen most commonly in adolescent and menopausal women, is initiated or exacerbated by cold weather, and typically presents as one or more recurrent erythrocyanotic nodules or plaques on the calves. The nodules may progress to form indurations, ulcerations, and scars.
MSH

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koronární jednotky

The hospital unit in which patients with acute cardiac disorders receive intensive care.
MSH

advanced and highly specialized care provided to medical or surgical patients with coronary disorders whose conditions are life-threatening and require comprehensive care and constant monitoring; it is usually administered in specially equipped units of a hospital.
CSP

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abstinenční syndrom

Physiological and psychological symptoms associated with withdrawal from the use of a drug after prolonged administration or habituation. The concept includes withdrawal from smoking or drinking, as well as withdrawal from an administered drug.
MSH

Substance withdrawal syndrome – a substance-specific organic brain syndrome that follows the discontinuation of administration or use, or reduction in intake of an addictive substance, e.g. opioids, barbiturates and alcohol; amphetamines or similarly acting sympathomimetics; cocaine; nicotine; sedatives, hypnotics, or anxiolytics. Syndrome manifests with diverse, often painful physical and psychological symptoms, which include but not limited to intense drug craving, anxiety, depression, insomnia, nausea, perspiration, body aches, tremors, hallucinations, and convulsions.
NCI

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anémie hemolytická kongenitální nesférocytární

Any one of a group of congenital hemolytic anemias in which there is no abnormal hemoglobin or spherocytosis and in which there is a defect of glycolysis in the erythrocyte. Common causes include deficiencies in GLUCOSE-6-PHOSPHATE ISOMERASE; PYRUVATE KINASE; and GLUCOSE-6-PHOSPHATE DEHYDROGENASE.
MSH

group of congenital hemolytic anemias in which there is no abnormal hemoglobin or spherocytosis and in which there is a defect of glycolysis in the erythrocyte; in some cases, pyruvate kinase deficiency has been demonstrated; in other cases, glucose-6-phosphate dehydrogenase deficiency has been demonstrated.
CSP

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fosvel

An organothiophosphate insecticide.
MSH

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jod – isotopy

Stable iodine atoms that have the same atomic number as the element iodine, but differ in atomic weight. I-127 is the only naturally occurring stable iodine isotope.
MSH

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Escherichia coli

species of gram negative, facultatively anaerobic, rod shaped bacteria commonly found in the lower part of the intestine of warm blooded animals; usually nonpathogenic, but some strains are known to produce diarrhea and pyogenic infections.
CSP

A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc.
MSH

Any bacterial organism that can be assigned to the species Escherichia coli.
NCI

A common, gram negative gut bacterium that has been studied intensively by geneticists because of its small genome size, normal lack of pathogenicity, and ease of growth in the laboratory.
NCI

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kosmetické přípravky

Substances intended to be applied to the human body for cleansing, beautifying, promoting attractiveness, or altering the appearance without affecting the body`s structure or functions. Included in this definition are skin creams, lotions, perfumes, lipsticks, fingernail polishes, eye and facial makeup preparations, permanent waves, hair colors, toothpastes, and deodorants, as well as any material intended for use as a component of a cosmetic product. (U.S. Food & Drug Administration Center for Food Safety & Applied Nutrition Office of Cosmetics Fact Sheet (web page) Feb 1995)
MSH

Cosmetics are products you apply to your body to clean it, make it more attractive or change the way it looks. They include

  • Hair dyes
  • Makeup
  • Perfumes
  • Skin-care creams

Products such as dandruff shampoo, fluoride toothpaste and antiperspirant deodorant are both cosmetics and drugs. A good way to tell if you`re buying a cosmetic that is also a drug is to see if the first ingredient listed is an “active ingredient.” The active ingredient is the chemical that makes the product effective, and the manufacturer must have proof that it`s safe for its intended use. To find out all the ingredients in a cosmetic you use, check the container. Manufacturers are required to list them. Labels such as “natural” and “hypoallergenic” have no official meaning. Companies can use them to mean whatever they want.

Food and Drug Administration


MEDLINEPLUS

A substance that is intended to be applied to the body to promote attractiveness without affecting the body`s structure or functions.
NCI

An article intended to be rubbed, poured, sprinkled, or sprayed on or introduced into or otherwise applied to the human body for cleansing, beautifying, promoting attractiveness or altering the appearance.
NCI

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sulfacetamid

An anti-infective agent that is used topically to treat skin infections and orally for urinary tract infections.
MSH

A synthetic sulfanylacetamide derivative with bacteriostatic activity. Sulfacetamide inhibits bacterial folic acid synthesis by competing with para amino benzoic acid. With a broad spectrum of action, it is used as an anti-infective topical agent to treat skin infections and as an oral agent for urinary tract infections. (NCI04)
NCI

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aneuploidie

The chromosomal constitution of cells which deviate from the normal by the addition or subtraction of CHROMOSOMES, chromosome pairs, or chromosome fragments. In a normally diploid cell (DIPLOIDY) the loss of a chromosome pair is termed nullisomy (symbol: 2N-2), the loss of a single chromosome is MONOSOMY (symbol: 2N-1), the addition of a chromosome pair is tetrasomy (symbol: 2N+2), the addition of a single chromosome is TRISOMY (symbol: 2N+1).
MSH

chromosomal constitution of cells which deviate from the normal by the addition or subtraction of chromosomes or chromosome pairs.
CSP

The occurrence of one or more extra or missing chromosomes leading to an unbalanced chromosome complement, or any chromosome number that is not an exact multiple of the haploid number (which is 46).
NCI

A chromosomal abnormality in which there is an addition or loss of chromosomes within a set (e.g., 23 + 22 or 23 + 24).
NCI

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tělesná zdatnost

The ability to carry out daily tasks and perform physical activities in a highly functional state, often as a result of physical conditioning.
MSH

state of well-being in which performance is optimal, often as a result of physical conditioning which may be prescribed for disease therapy.
CSP

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iprindol

A tricyclic antidepressant that has actions and uses similar to those of AMITRIPTYLINE, but has only weak antimuscarinic and sedative effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p257)
MSH

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estetika stomatologická

Skills, techniques, standards, and principles used to improve the art and symmetry of the teeth and face to improve the appearance as well as the function of the teeth, mouth, and face. (From Boucher`s Clinical Dental Terminology, 4th ed, p108)
MSH

Who doesn`t want a perfect smile? While few people have one naturally, almost anyone can get one with the help of their dentist. In addition to orthodontic treatment, which can straighten your teeth, recent advances in dental materials and techniques offer near-perfect teeth that are almost as strong as the originals.

Things your dentist can do to improve your smile include

  • Bleaching to make teeth whiter
  • Repairing chips or rough spots with fillings that match your teeth
  • Filling cavities with tooth-colored materials
  • Reshaping teeth that don`t match the others
  • Closing gaps between teeth
  • Covering broken teeth with porcelain crowns


MEDLINEPLUS

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