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DNA komplementární

Single-stranded complementary DNA synthesized from an RNA template by the action of RNA-dependent DNA polymerase. cDNA (i.e., complementary DNA, not circular DNA, not C-DNA) is used in a variety of molecular cloning experiments as well as serving as a specific hybridization probe.
MSH

single-stranded complementary DNA synthesized from an RNA template by the action of RNA-dependent DNA polymerase; used in a variety of molecular cloning experiments as well as serving as a specific hybridization probe.
CSP

Single-stranded DNA that is complementary to messenger RNA or DNA that has been synthesized from messenger RNA by reverse transcriptase.
NCI

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methohexital

An intravenous anesthetic with a short duration of action that may be used for induction of anesthesia.
MSH

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sulfacetamid

An anti-infective agent that is used topically to treat skin infections and orally for urinary tract infections.
MSH

A synthetic sulfanylacetamide derivative with bacteriostatic activity. Sulfacetamide inhibits bacterial folic acid synthesis by competing with para amino benzoic acid. With a broad spectrum of action, it is used as an anti-infective topical agent to treat skin infections and as an oral agent for urinary tract infections. (NCI04)
NCI

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Haemonchus

A genus of parasitic nematode worms which infest the duodenum and stomach of domestic and wild herbivores, which ingest it with the grasses (POACEAE) they eat. Infestation of man is accidental.
MSH

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tělesná zdatnost

The ability to carry out daily tasks and perform physical activities in a highly functional state, often as a result of physical conditioning.
MSH

state of well-being in which performance is optimal, often as a result of physical conditioning which may be prescribed for disease therapy.
CSP

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enalapril

One of the ANGIOTENSIN-CONVERTING ENZYME INHIBITORS that is used to treat hypertension.
MSH

1-carboxy-3-phenylpropyl-L-alanyl- L-proline (as 1`-ethyl ester, maleate 1:1), is an ACE inhibitor used as an antihypertensive.
CSP

A dicarbocyl-containing peptide and angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. As a prodrug, enalapril is converted by de-esterification into its active form enalaprilat. Enalaprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. Enalapril also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow.
NCI

An antihypertensive agent that can also be used to slow or prevent the progression of heart disease in people with childhood cancer treated with drugs that may be harmful to the heart.
NCI

a drug used to treat hypertension
CHV

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vápníkové kanály

Voltage-dependent cell membrane glycoproteins selectively permeable to calcium ions. They are categorized as L-, T-, N-, P-, Q-, and R-types based on the activation and inactivation kinetics, ion specificity, and sensitivity to drugs and toxins. The L- and T-types are present throughout the cardiovascular and central nervous systems and the N-, P-, Q-, & R-types are located in neuronal tissue.
MSH

voltage-dependent cell membrane glycoproteins selectively permeable to calcium ions.
CSP

An ion channel with selective permeability to calcium.
NCI

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methylhistidiny

Histidine substituted in any position with one or more methyl groups.
MSH

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sulfisomidin

A sulfanilamide antibacterial agent.
MSH

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syndrom mnohočetného hamartomu

A hereditary disease characterized by multiple ectodermal, mesodermal, and endodermal nevoid and neoplastic anomalies. Facial trichilemmomas and papillomatous papules of the oral mucosa are the most characteristic lesions. Individuals with this syndrome have a high risk of BREAST CANCER; THYROID CANCER; and ENDOMETRIAL CANCER. This syndrome is associated with mutations in the gene for PTEN PHOSPHATASE.
MSH

An inherited disorder marked by the formation of many noncancerous growths called hamartomas. These growths occur in the skin, breast, thyroid, colon, intestines, and inside of the mouth. Patients with Cowden syndrome are at increased risk of certain types of cancer, including breast and thyroid.
NCI

An autosomal dominant hereditary syndrome characterized by a variety of hamartomas and neoplasms including verrucous skin lesions, fibromas of the oral cavity, facial trichilemmomas, hamartomatous colonic polyps, thyroid neoplasms, breast cancer, and dysplastic gangliocytomas of the cerebellum.
NCI

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fytosteroly

A class of organic compounds known as STEROLS or STEROIDS derived from plants.
MSH

A class of dietary sterols present in plants with chemical structures nearly identical to cholesterol.
NCI

Any sterol found in the plant kingdom.
NCI

A plant-based compound that can compete with dietary cholesterol to be absorbed by the intestines, resulting in lower blood cholesterol levels. Phytosterols may have some effect in cancer prevention. Also called plant sterol.
NCI

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karotická endarterektomie

The excision of the thickened, atheromatous tunica intima of a carotid artery.
MSH

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kostní svalek

The bony deposit formed between and around the broken ends of BONE FRACTURES during normal healing.
MSH

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metronidazol

A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS. It has also been proposed as a radiation sensitizer for hypoxic cells. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985, p133), this substance may reasonably be anticipated to be a carcinogen (Merck, 11th ed).
MSH

antiprotozoal and antibacterial effective against obligate anaerobes.
CSP

A drug that is used to treat infection and is being studied in the treatment of cancer. It is a type of antibacterial, antiprotozoal, and anthelmintic.
NCI

a drug that treats bacterial and fungal infection
CHV

A synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities. Although its mechanism of action is not fully elucidated, un-ionized metronidazole is readily taken up by obligate anaerobic organisms and is subsequently reduced by low-redox potential electron-transport proteins to an active, intermediate product. Reduced metronidazole causes DNA strand breaks, thereby inhibiting DNA synthesis and bacterial cell growth. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39503&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39503&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C651″ NCI Thesaurus)
PDQ

A synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities. Although its mechanism of action is not fully elucidated, un-ionized metronidazole is readily taken up by obligate anaerobic organisms and is subsequently reduced by low-redox potential electron-transport proteins to an active, intermediate product. Reduced metronidazole causes DNA strand breaks, thereby inhibiting DNA synthesis and bacterial cell growth.
NCI

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superego

The component of the personality associated with ethics, standards, and self-criticism – the “conscience”. It is derived mainly from identification with parents and parent substitutes.
MSH

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nebezpečný odpad

Waste products which, upon release into the atmosphere, water or soil, cause health risks to humans or animals through skin contact, inhalation or ingestion. Hazardous waste sites which contain hazardous waste substances go here.
MSH

Even if you use them properly, many chemicals can still harm human health and the environment. When you throw these substances away, they become hazardous waste. Some hazardous wastes come from products in our homes. Our garbage can include such hazardous wastes as old batteries, bug spray cans and paint thinner. U.S. residents generate 1.6 million tons of household hazardous waste per year. Hazardous waste is also a by-product of manufacturing.

You may have hazardous wastes in your basement or garage. How do you get rid of them? Don`t pour them down the drain, flush them or put them in the garbage. See if you can donate or recycle. Many communities have household hazardous waste collection programs. Check to see if there is one in your area.

Environmental Protection Agency


MEDLINEPLUS

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piperazine

saturated 6-membered ring structure with 2 nitrogen atoms.
CSP

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endoplazmatické retikulum

A system of cisternae in the CYTOPLASM of many cells. In places the endoplasmic reticulum is continuous with the plasma membrane (CELL MEMBRANE) or outer membrane of the nuclear envelope. If the outer surfaces of the endoplasmic reticulum membranes are coated with ribosomes, the endoplasmic reticulum is said to be rough-surfaced (ENDOPLASMIC RETICULUM, ROUGH); otherwise it is said to be smooth-surfaced (ENDOPLASMIC RETICULUM, SMOOTH). (King & Stansfield, A Dictionary of Genetics, 4th ed)
MSH

system of cisternae in the cytoplasm of many cells; in places the endoplasmic reticulum is continuous with the plasma membrane or outer membrane of the nuclear envelope; rough endoplasmic reticulum membranes are coated with ribosomes and are involved in protein synthesis and transport; smooth endoplasmic reticulum is involved in steroid synthesis.
CSP

The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). [ISBN:0198506732 “Oxford Dictionary of Biochemistry and Molecular Biology”]
GO

a part of the cell structure
CHV

The endoplasmic reticulum is a network of tubular membranes within the cytoplasm of the cell, occurring either with a smooth surface (smooth endoplasmic reticulum) or studded with ribosomes (rough endoplasmic reticulum), involved in the transport of materials. (Infoplease Dictionary)
NCI

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kandidóza

Infection with a fungus of the genus CANDIDA. It is usually a superficial infection of the moist areas of the body and is generally caused by CANDIDA ALBICANS. (Dorland, 27th ed)
MSH

infection with a fungus of the genus Candida; usually a superficial infection of the moist areas of the body and is generally caused by Candida albicans; includes chronic mucocutaneous candidiasis, cutaneous candidiasis, oral candidiasis (thrush), and monilial vaginitis.
CSP

A condition in which Candida albicans, a type of yeast, grows out of control in moist skin areas of the body. It is usually a result of a weakened immune system, but can be a side effect of chemotherapy or treatment with antibiotics. Thrush usually affects the mouth (oral thrush); however, rarely, it spreads throughout the entire body.
NCI

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mikrochemie

The development and use of techniques and equipment to study or perform chemical reactions, with small quantities of materials, frequently less than a milligram or a milliliter.
MSH

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chirurgické oddělení nemocnice

Hospital department which administers all departmental functions and the provision of surgical diagnostic and therapeutic services.
MSH

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zdravotnické plánování – rady

Organized groups serving in advisory capacities related to health planning activities.
MSH

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GIBERT EN PITIRIASIS ARROSATUA

A mild exanthematous inflammation of unknown etiology. It is characterized by the presence of salmon-colored maculopapular lesions. The most striking feature is the arrangement of the lesions such that the long axis is parallel to the lines of cleavage. The eruptions are usually generalized, affecting chiefly the trunk, and the course is often self-limiting.
MSH

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koronavirus krocanů

A species of CORONAVIRUS causing enteritis in turkeys and pullets.
MSH

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kapsida

The outer protein protective shell of a virus, which protects the viral nucleic acid.
MSH

protein shell which surrounds the virus nucleic acid; has icosahedral, helical, or complex symmetry.
CSP

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mikroskopie ultrafialová

Microscopy in which the image is formed by ultraviolet radiation and is displayed and recorded by means of photographic film.
MSH

microscopy in which the image is formed by ultraviolet radiation.
CSP

The study and photographing of microscope specimens in ultraviolet light. It is particularly useful when all parts of the specimen viewed are equally transparent in the visible region. (The Photonics Dictionary)
NCI

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přežití

Continuance of life or existence especially under adverse conditions; includes methods and philosophy of survival.
MSH

In cancer, survivorship covers the physical, psychosocial, and economic issues of cancer, from diagnosis until the end of life. It focuses on the health and life of a person with cancer beyond the diagnosis and treatment phases. Survivorship includes issues related to the ability to get health care and follow-up treatment, late effects of treatment, second cancers, and quality of life. Family members, friends, and caregivers are also part of the survivorship experience.
NCI

Continuance of life or existence especially under adverse conditions; includes methods and philosophy of survival.
NCI

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nedoslýchavost percepční

Hearing loss resulting from damage to the COCHLEA and the sensorineural elements which lie internally beyond the oval and round windows. These elements include the AUDITORY NERVE and its connections in the BRAINSTEM.
MSH

due to lesions of the cochlea and the auditory division of the eighth cranial nerve; problem of cellular dysfunction rather than airborne conduction.
CSP

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viry rostlin

Viruses parasitic on plants higher than bacteria.
MSH

viruses that replicate in and may produce diseases of higher plants; see RTs for specific organisms.
CSP

Viruses that replicate in and may produce diseases of higher plants.
NCI

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enzymy – aktivace

Conversion of an inactive form of an enzyme to one possessing metabolic activity. It includes 1, activation by ions (activators); 2, activation by cofactors (coenzymes); and 3, conversion of an enzyme precursor (proenzyme or zymogen) to an active enzyme.
MSH

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