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oxazolon

Immunologic adjuvant and sensitizing agent.
MSH

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methakryláty

Acrylic acids or acrylates which are substituted in the C-2 position with a methyl group.
MSH

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chromozómy lidské, 16-18

The short, submetacentric human chromosomes, called group E in the human chromosome classification. This group consists of chromosome pairs 16, 17, and 18.
MSH

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guanylcyklasa

An enzyme that catalyzes the conversion of GTP to 3`,5`-cyclic GMP and pyrophosphate. It also acts on ITP and dGTP. (From Enzyme Nomenclature, 1992) EC 4.6.1.2.
MSH

Guanylate cyclase (GC) is an enzyme that converts GTP to the second messenger cyclic GMP (cGMP). There are two forms: plasma membrane GCs that are receptors for hormones, and intracellular soluble GCs that are activated by the gaseous second messenger nitric oxide (NO). EC 4.6.1.2
NCI

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pohlavní předvýběr

Methods for controlling genetic SEX of offspring.
MSH

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oxypurinol

A xanthine oxidase inhibitor.
MSH

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methohexital

An intravenous anesthetic with a short duration of action that may be used for induction of anesthesia.
MSH

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chrysarobin

An extract of Goa powder; a complex mixture of reduction products of chrysophanic acid, emodin, and emodin monomethyl ether; used locally in ringworm, psoriasis, and eczema.
NCI

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Haemonchus

A genus of parasitic nematode worms which infest the duodenum and stomach of domestic and wild herbivores, which ingest it with the grasses (POACEAE) they eat. Infestation of man is accidental.
MSH

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šok septický

Sepsis associated with HYPOTENSION or hypoperfusion despite adequate fluid resuscitation. Perfusion abnormalities may include, but are not limited to LACTIC ACIDOSIS; OLIGURIA; or acute alteration in mental status.
MSH

shock caused by infection; frequently caused by gram negative bacteria, although some cases have been caused by other bacteria, viruses, fungi, and protozoa; characterized by fever, chills, tachycardia, tachypnea, and hypotension.
CSP

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Bolest v končetině

Painful sensation in the upper or lower extremities.
NCI

A disorder characterized by marked discomfort sensation in the upper or lower extremities.
NCI

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methylhistidiny

Histidine substituted in any position with one or more methyl groups.
MSH

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cirkulární dichroismus

A change from planar to elliptic polarization when an initially plane-polarized light wave traverses an optically active medium. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
MSH

planar polarization converts to eliptic polarization when plane polarized light travels through an optically active medium.
CSP

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syndrom mnohočetného hamartomu

A hereditary disease characterized by multiple ectodermal, mesodermal, and endodermal nevoid and neoplastic anomalies. Facial trichilemmomas and papillomatous papules of the oral mucosa are the most characteristic lesions. Individuals with this syndrome have a high risk of BREAST CANCER; THYROID CANCER; and ENDOMETRIAL CANCER. This syndrome is associated with mutations in the gene for PTEN PHOSPHATASE.
MSH

An inherited disorder marked by the formation of many noncancerous growths called hamartomas. These growths occur in the skin, breast, thyroid, colon, intestines, and inside of the mouth. Patients with Cowden syndrome are at increased risk of certain types of cancer, including breast and thyroid.
NCI

An autosomal dominant hereditary syndrome characterized by a variety of hamartomas and neoplasms including verrucous skin lesions, fibromas of the oral cavity, facial trichilemmomas, hamartomatous colonic polyps, thyroid neoplasms, breast cancer, and dysplastic gangliocytomas of the cerebellum.
NCI

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sigmoideum – nemoci

Pathological processes in the SIGMOID COLON region of the large intestine (INTESTINE, LARGE).
MSH

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pankreas – transplantace

The transference of a pancreas from one human or animal to another.
MSH

transferring pancreatic cells or tissue, or whole pancreas, within an individual or between individuals of the same or different species; for specific pancreatic islet cells use PANCREATIC ISLET CELL TRANSPLANTATION.
CSP

The pancreas is an organ that makes insulin and enzymes that help the body digest and use food. A pancreas transplant is surgery to place a healthy pancreas from a donor into a person with a diseased pancreas. A common reason for this type of damage is diabetes. Pancreas transplants can enable people with type 1 diabetes to give up insulin shots. An experimental procedure called islet cell transplantation transplants only the parts of the pancreas that make insulin.

People who have transplants must take drugs to keep their body from rejecting the new pancreas for the rest of their lives. They must also have regular follow-up care.


MEDLINEPLUS

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metronidazol

A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS. It has also been proposed as a radiation sensitizer for hypoxic cells. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985, p133), this substance may reasonably be anticipated to be a carcinogen (Merck, 11th ed).
MSH

antiprotozoal and antibacterial effective against obligate anaerobes.
CSP

A drug that is used to treat infection and is being studied in the treatment of cancer. It is a type of antibacterial, antiprotozoal, and anthelmintic.
NCI

a drug that treats bacterial and fungal infection
CHV

A synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities. Although its mechanism of action is not fully elucidated, un-ionized metronidazole is readily taken up by obligate anaerobic organisms and is subsequently reduced by low-redox potential electron-transport proteins to an active, intermediate product. Reduced metronidazole causes DNA strand breaks, thereby inhibiting DNA synthesis and bacterial cell growth. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39503&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39503&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C651″ NCI Thesaurus)
PDQ

A synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities. Although its mechanism of action is not fully elucidated, un-ionized metronidazole is readily taken up by obligate anaerobic organisms and is subsequently reduced by low-redox potential electron-transport proteins to an active, intermediate product. Reduced metronidazole causes DNA strand breaks, thereby inhibiting DNA synthesis and bacterial cell growth.
NCI

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rozštěp rtu

Congenital defect in the upper lip where the maxillary prominence fails to merge with the merged medial nasal prominences. It is thought to be caused by faulty migration of the mesoderm in the head region.
MSH

congenital defect in the upper lip where the maxillary prominence fails to merge with the merged medial nasal prominences; thought to be caused by faulty migration of the mesoderm in the head region.
CSP

A congenital abnormality consisting of one or more clefts (splits) in the upper lip, which may be accompanied by a cleft palate; it is the result of the failure of the embryonic parts of the lip to fuse.
NCI

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nebezpečný odpad

Waste products which, upon release into the atmosphere, water or soil, cause health risks to humans or animals through skin contact, inhalation or ingestion. Hazardous waste sites which contain hazardous waste substances go here.
MSH

Even if you use them properly, many chemicals can still harm human health and the environment. When you throw these substances away, they become hazardous waste. Some hazardous wastes come from products in our homes. Our garbage can include such hazardous wastes as old batteries, bug spray cans and paint thinner. U.S. residents generate 1.6 million tons of household hazardous waste per year. Hazardous waste is also a by-product of manufacturing.

You may have hazardous wastes in your basement or garage. How do you get rid of them? Don`t pour them down the drain, flush them or put them in the garbage. See if you can donate or recycle. Many communities have household hazardous waste collection programs. Check to see if there is one in your area.

Environmental Protection Agency


MEDLINEPLUS

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retroviry opic

Classes of retroviruses for which monkeys or apes are hosts. Those isolated from the West African green monkey and the Asian rhesus macaque monkey are of particular interest because of their similarities to viruses causing cancer and acquired immunodeficiency syndrome (AIDS) in humans.
MSH

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kyselina pantothenová

A butyryl-beta-alanine that can also be viewed as pantoic acid complexed with BETA ALANINE. It is incorporated into COENZYME A and protects cells against peroxidative damage by increasing the level of GLUTATHIONE.
MSH

A water-soluble vitamin ubiquitously found in plants and animal tissues with antioxidant property. Vitamin B5 is a component of coenzyme A (CoA) and a part of the vitamin B2 complex. Vitamin B5 is a growth factor and is essential for various metabolic functions, including the metabolism of carbohydrates, proteins, and fatty acids. This vitamin is also involved in the synthesis of cholesterol, lipids, neurotransmitters, steroid hormones, and hemoglobin.
NCI

Water-soluble vitamin that is a component of coenzyme A and phosphopantetheine, which are involved in fatty acid metabolism. (DRI)
NCI

A nutrient in the vitamin B complex that the body needs in small amounts to function and stay healthy. Pantothenic acid helps some enzymes use foods and make many substances used in the body and protects cells against damage from peroxides. It is found in almost all plant and animal foods. Pantothenic acid is water-soluble (can dissolve in water) and must be taken in every day.
NCI

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mikrochemie

The development and use of techniques and equipment to study or perform chemical reactions, with small quantities of materials, frequently less than a milligram or a milliliter.
MSH

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klonidin

An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
MSH

alpha-2 adrenergic agonist that crosses the blood-brain barrier; acts centrally by reducing sympathetic tone, resulting in a fall in diastolic and systolic blood pressure and a reduction in heart rate; also acts peripherally.
CSP

a hypertension treatment drug
CHV

The active ingredient in a drug used to treat high blood pressure. It is also being studied in the treatment of certain types of cancer pain. It blocks the release of chemicals from nerve endings that make blood vessels constrict (get narrower). Clonidine is a type of antihypertensive agent and a type of alpha-adrenergic agonist.
NCI

An imidazoline derivate and centrally-acting alpha-adrenergic agonist, with antihypertensive activity. Clonidine binds to and stimulates central alpha-2 adrenergic receptors, thereby reducing the amount of norepinephrine (NE) release and thus decreasing sympathetic outflow to the heart, kidneys, and peripheral vasculature. The reduction in sympathetic outflow leads to decreased peripheral vascular resistance, decreased blood pressure, and decreased heart rate. In addition, clonidine binds to imidazoline receptor subtype 1 (I1), which may also contribute to a reduction in blood pressure.
NCI

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zdravotnické plánování – rady

Organized groups serving in advisory capacities related to health planning activities.
MSH

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stárnutí kůže

The process of aging due to changes in the structure and elasticity of the skin over time. It may be a part of physiological aging or it may be due to the effects of ultraviolet radiation, usually through exposure to sunlight.
MSH

Your skin changes as you age. You might notice wrinkles, age spots and dryness. Your skin also becomes thinner and loses fat, making it less plump and smooth. It might take longer to heal, too.

Sunlight is a major cause of skin aging. You can protect yourself by staying out of the sun when it is strongest, using sunscreen with an SPF of 15 or higher, wearing protective clothing, and avoiding sunlamps and tanning beds. Cigarette smoking also contributes to wrinkles. The wrinkling increases with the amount of cigarettes and number of years a person has smoked.

Many products claim to revitalize aging skin or reduce wrinkles, but the Food and Drug Administration has approved only a few for sun-damaged or aging skin. Various treatments soothe dry skin and reduce the appearance of age spots.

NIH: National Institute on Aging


MEDLINEPLUS

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Paragonimus westermani

A species of lung fluke infecting humans and other animals, and found chiefly in Asia and the Far East.
MSH

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mikroskopie ultrafialová

Microscopy in which the image is formed by ultraviolet radiation and is displayed and recorded by means of photographic film.
MSH

microscopy in which the image is formed by ultraviolet radiation.
CSP

The study and photographing of microscope specimens in ultraviolet light. It is particularly useful when all parts of the specimen viewed are equally transparent in the visible region. (The Photonics Dictionary)
NCI

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uhlí

A natural fuel formed by partial decomposition of vegetable matter under certain environmental conditions.
MSH

natural fossil fuel formed by partial decomposition of vegetable matter under certain environmental conditions.
CSP

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nedoslýchavost percepční

Hearing loss resulting from damage to the COCHLEA and the sensorineural elements which lie internally beyond the oval and round windows. These elements include the AUDITORY NERVE and its connections in the BRAINSTEM.
MSH

due to lesions of the cochlea and the auditory division of the eighth cranial nerve; problem of cellular dysfunction rather than airborne conduction.
CSP

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viry pomalé – infekce

Diseases of viral origin, characterized by incubation periods of months to years, insidious onset of clinical manifestations, and protracted clinical course. Though the disease process is protracted, viral multiplication may not be unusually slow. Conventional viruses produce slow virus diseases such as SUBACUTE SCLEROSING PANENCEPHALITIS, progressive multifocal leukoencephalopathy (LEUKOENCEPHALOPATHY, PROGRESSIVE MULTIFOCAL), and AIDS. Diseases produced by unconventional agents were originally considered part of this group. They are now called PRION DISEASES.
MSH

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