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methakryláty

Acrylic acids or acrylates which are substituted in the C-2 position with a methyl group.
MSH

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zkouška hemolytické aktivity komplementu

A screening assay for circulating COMPLEMENT PROTEINS. Diluted SERUM samples are added to antibody-coated ERYTHROCYTES and the percentage of cell lysis is measured. The values are expressed by the so called CH50, in HEMOLYTIC COMPLEMENT units per milliliter, which is the dilution of serum required to lyse 50 percent of the erythrocytes in the assay.
MSH

A screening assay for circulating complement proteins in which diluted serum samples are added to antibody-coated erythrocytes and the percentage of cell lysis is measured. The values are expressed in hemolytic complement units per milliliter (CH50), the dilution of serum required to lyse 50 percent of the erythrocytes in the assay.
NCI

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pyruvátdekarboxylasa

Catalyzes the decarboxylation of an alpha keto acid to an aldehyde and carbon dioxide. Thiamine pyrophosphate is an essential cofactor. In lower organisms, which ferment glucose to ethanol and carbon dioxide, the enzyme irreversibly decarboxylates pyruvate to acetaldehyde. EC 4.1.1.1.
MSH

also another name for EC 1.2.4.1, PYRUVATE DEHYDROGENASE, do not confuse.
CSP

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guanylcyklasa

An enzyme that catalyzes the conversion of GTP to 3`,5`-cyclic GMP and pyrophosphate. It also acts on ITP and dGTP. (From Enzyme Nomenclature, 1992) EC 4.6.1.2.
MSH

Guanylate cyclase (GC) is an enzyme that converts GTP to the second messenger cyclic GMP (cGMP). There are two forms: plasma membrane GCs that are receptors for hormones, and intracellular soluble GCs that are activated by the gaseous second messenger nitric oxide (NO). EC 4.6.1.2
NCI

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vzduchové vaky

Thin-walled sacs or spaces which function as a part of the respiratory system in birds, fishes, insects, and mammals.
MSH

an organ in modern bony fish that develops from latral or dorsal wall of gut, and can fill with oxygen for bouyancy, hearing, or sound production.
CSP

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methohexital

An intravenous anesthetic with a short duration of action that may be used for induction of anesthesia.
MSH

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koncentrační tábory

Facilities in which war or political prisoners are confined.
MSH

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chinazoliny

two ring heterocyclic compound.
CSP

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Haemonchus

A genus of parasitic nematode worms which infest the duodenum and stomach of domestic and wild herbivores, which ingest it with the grasses (POACEAE) they eat. Infestation of man is accidental.
MSH

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1-propanol

A colorless liquid made by oxidation of aliphatic hydrocarbons that is used as a solvent and chemical intermediate.
MSH

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methylhistidiny

Histidine substituted in any position with one or more methyl groups.
MSH

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Connecticut

A state in the northeastern United States. Its capital is Hartford.
NCI

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aspects of radiation effects

Used for effects of ionizing and nonionizing radiation upon living organisms, organs and tissues, and their constituents, and upon physiologic processes. It includes the effect of irradiation on drugs and chemicals.
MSH

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syndrom mnohočetného hamartomu

A hereditary disease characterized by multiple ectodermal, mesodermal, and endodermal nevoid and neoplastic anomalies. Facial trichilemmomas and papillomatous papules of the oral mucosa are the most characteristic lesions. Individuals with this syndrome have a high risk of BREAST CANCER; THYROID CANCER; and ENDOMETRIAL CANCER. This syndrome is associated with mutations in the gene for PTEN PHOSPHATASE.
MSH

An inherited disorder marked by the formation of many noncancerous growths called hamartomas. These growths occur in the skin, breast, thyroid, colon, intestines, and inside of the mouth. Patients with Cowden syndrome are at increased risk of certain types of cancer, including breast and thyroid.
NCI

An autosomal dominant hereditary syndrome characterized by a variety of hamartomas and neoplasms including verrucous skin lesions, fibromas of the oral cavity, facial trichilemmomas, hamartomatous colonic polyps, thyroid neoplasms, breast cancer, and dysplastic gangliocytomas of the cerebellum.
NCI

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algoritmy

A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task.
MSH

A defined procedure for solving a problem. Applied to a problem-solving procedure implemented in software to be executed by a computer.
NCI

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metronidazol

A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS. It has also been proposed as a radiation sensitizer for hypoxic cells. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985, p133), this substance may reasonably be anticipated to be a carcinogen (Merck, 11th ed).
MSH

antiprotozoal and antibacterial effective against obligate anaerobes.
CSP

A drug that is used to treat infection and is being studied in the treatment of cancer. It is a type of antibacterial, antiprotozoal, and anthelmintic.
NCI

a drug that treats bacterial and fungal infection
CHV

A synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities. Although its mechanism of action is not fully elucidated, un-ionized metronidazole is readily taken up by obligate anaerobic organisms and is subsequently reduced by low-redox potential electron-transport proteins to an active, intermediate product. Reduced metronidazole causes DNA strand breaks, thereby inhibiting DNA synthesis and bacterial cell growth. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39503&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39503&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C651″ NCI Thesaurus)
PDQ

A synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities. Although its mechanism of action is not fully elucidated, un-ionized metronidazole is readily taken up by obligate anaerobic organisms and is subsequently reduced by low-redox potential electron-transport proteins to an active, intermediate product. Reduced metronidazole causes DNA strand breaks, thereby inhibiting DNA synthesis and bacterial cell growth.
NCI

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sexuální chování – antikoncepce

Behavior patterns of those practicing CONTRACEPTION.
MSH

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rentgendiagnostika – dvourozměrná projekce

A method of producing a high-quality scan by digitizing and subtracting the images produced by high- and low-energy x-rays.
MSH

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nebezpečný odpad

Waste products which, upon release into the atmosphere, water or soil, cause health risks to humans or animals through skin contact, inhalation or ingestion. Hazardous waste sites which contain hazardous waste substances go here.
MSH

Even if you use them properly, many chemicals can still harm human health and the environment. When you throw these substances away, they become hazardous waste. Some hazardous wastes come from products in our homes. Our garbage can include such hazardous wastes as old batteries, bug spray cans and paint thinner. U.S. residents generate 1.6 million tons of household hazardous waste per year. Hazardous waste is also a by-product of manufacturing.

You may have hazardous wastes in your basement or garage. How do you get rid of them? Don`t pour them down the drain, flush them or put them in the garbage. See if you can donate or recycle. Many communities have household hazardous waste collection programs. Check to see if there is one in your area.

Environmental Protection Agency


MEDLINEPLUS

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slitiny

A mixture of metallic elements or compounds with other metallic or metalloid elements in varying proportions.
MSH

mixture of two or more metals or of one or more metals with certain metalloids that are mutually soluble in the molten condition; distinguished as binary, ternary, quaternary, etc., depending on the number of metals in the mixture.
CSP

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mikrochemie

The development and use of techniques and equipment to study or perform chemical reactions, with small quantities of materials, frequently less than a milligram or a milliliter.
MSH

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Coombsův test

Hemagglutination test in which Coombs` reagent (antiglobulin, or anti-human globulin rabbit immune serum) is added to detect incomplete (non-agglutinating, univalent, blocking) antibodies coating erythrocytes. The direct test is applied to red cells which have been coated with antibody in vivo (e.g., in hemolytic disease of newborn, autoimmune hemolytic anemia, and transfusion reactions). The indirect test is applied to serum to detect the presence of antibody (e.g., in detection of incompatibility in cross-matching tests, detection and identification of irregular antibodies, and in detection of antibodies not identifiable by other means).
MSH

A laboratory test to identify antibodies that can bind to the surface of red blood cells or platelets and destroy them. This test is used to diagnose certain blood disorders in which patients make antibodies to their own red blood cells or platelets. It is also used to determine blood type.
NCI

Hemagglutination test in which Coombs` reagent (antiglobulin, or anti-human globulin rabbit immune serum) is added to detect incomplete (non-agglutinating, univalent, blocking) antibodies coating erythrocytes. The direct test is applied to red cells which have been coated with antibody in vivo (e.g., in hemolytic disease of newborn, autoimmune hemolytic anemia, and transfusion reactions). The indirect test is applied to serum to detect the presence of antibody (e.g., in detection of incompatibility in cross-matching tests, detection and identification of irregular antibodies, and in detection of antibodies not identifiable by other means). (MeSH)
NCI

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vztek

Fury; violent, intense anger.
MSH

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zdravotnické plánování – rady

Organized groups serving in advisory capacities related to health planning activities.
MSH

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talasémie alfa

A disorder characterized by reduced synthesis of the alpha chains of hemoglobin. The severity of this condition can vary from mild anemia to death, depending on the number of genes deleted.
MSH

A genetic hematologic disorder characterized by partial or complete absence of the alpha globin chains of the heme molecule.
NCI

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mikroskopie ultrafialová

Microscopy in which the image is formed by ultraviolet radiation and is displayed and recorded by means of photographic film.
MSH

microscopy in which the image is formed by ultraviolet radiation.
CSP

The study and photographing of microscope specimens in ultraviolet light. It is particularly useful when all parts of the specimen viewed are equally transparent in the visible region. (The Photonics Dictionary)
NCI

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koronární jednotky

The hospital unit in which patients with acute cardiac disorders receive intensive care.
MSH

advanced and highly specialized care provided to medical or surgical patients with coronary disorders whose conditions are life-threatening and require comprehensive care and constant monitoring; it is usually administered in specially equipped units of a hospital.
CSP

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potkani – mutantní kmeny

Rats bearing mutant genes which are phenotypically expressed in the animals.
MSH

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nedoslýchavost percepční

Hearing loss resulting from damage to the COCHLEA and the sensorineural elements which lie internally beyond the oval and round windows. These elements include the AUDITORY NERVE and its connections in the BRAINSTEM.
MSH

due to lesions of the cochlea and the auditory division of the eighth cranial nerve; problem of cellular dysfunction rather than airborne conduction.
CSP

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anémie hemolytická kongenitální nesférocytární

Any one of a group of congenital hemolytic anemias in which there is no abnormal hemoglobin or spherocytosis and in which there is a defect of glycolysis in the erythrocyte. Common causes include deficiencies in GLUCOSE-6-PHOSPHATE ISOMERASE; PYRUVATE KINASE; and GLUCOSE-6-PHOSPHATE DEHYDROGENASE.
MSH

group of congenital hemolytic anemias in which there is no abnormal hemoglobin or spherocytosis and in which there is a defect of glycolysis in the erythrocyte; in some cases, pyruvate kinase deficiency has been demonstrated; in other cases, glucose-6-phosphate dehydrogenase deficiency has been demonstrated.
CSP

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