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cefatrizin

Orally active semisynthetic cephalosporin antibiotic with broad-spectrum activity.
MSH

A broad-spectrum, semisynthetic, first-generation cephalosporin with antibacterial activity. Cefatrizine binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.
NCI

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dentice – fyziologické jevy

Physiological processes and properties of the DENTITION.
MSH

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tetradekanoylforbolacetát

A phorbol ester found in CROTON OIL with very effective tumor promoting activity. It stimulates the synthesis of both DNA and RNA.
MSH

A substance being studied in the treatment of leukemias and lymphomas. It is also being studied in the treatment of other types of cancer. Tetradecanoylphorbol acetate affects many cell actions and may cause tumor cells to die. It is a type of phorbol ester.
NCI

A phorbol ester with potential antineoplastic effects. Tetradecanoylphorbol acetate (TPA) induces maturation and differentiation of hematopoietic cell lines, including leukemic cells. This agent may induce gene expression and protein kinase C (PKC) activity. In addition to potential antineoplastic effects, TPA may exhibit tumor promoting activity. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=43661&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=43661&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C866″ NCI Thesaurus)
PDQ

A phorbol ester with potential antineoplastic effects. Tetradecanoylphorbol acetate (TPA) induces maturation and differentiation of hematopoietic cell lines, including leukemic cells. This agent may induce gene expression and protein kinase C (PKC) activity. In addition to potential antineoplastic effects, TPA may exhibit tumor promoting activity. (NCI04)
NCI

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kyseliny heptylové

7-carbon saturated monocarboxylic acids.
MSH

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populace – surveillance

Ongoing scrutiny of a population (general population, study population, target population, etc.), generally using methods distinguished by their practicability, uniformity, and frequently their rapidity, rather than by complete accuracy.
MSH

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M fáze buněčného dělení

The period of the cell cycle when CELLS divide their nucleus and cytoplasm.
MSH

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multiinstitucionální systémy

Institutional systems consisting of more than one health facility which have cooperative administrative arrangements through merger, affiliation, shared services, or other collective ventures.
MSH

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thalium – radioisotopy

Unstable isotopes of thallium that decay or disintegrate emitting radiation. Tl atoms with atomic weights 198-202, 204, and 206-210 are thallium radioisotopes.
MSH

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heterochromatin

The portion of chromosome material that remains condensed and is transcriptionally inactive during INTERPHASE.
MSH

regions of the genome that are permanently in a highly condensed condition and are not genetically expressed.
CSP

A compact and highly condensed form of chromatin. [GOC:elh]
GO

A tightly packed area of chromatin that may function to protect chromosome integrity and regulate gene expression.
NCI

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ERDITZE ONDORENGO ODOLJARIO GARRANTZITSUA

Excess blood loss from uterine bleeding associated with OBSTETRIC LABOR or CHILDBIRTH. It is defined as blood loss greater than 500 ml or of the amount that adversely affects the maternal physiology, such as BLOOD PRESSURE and HEMATOCRIT. Postpartum hemorrhage is divided into two categories, immediate (within first 24 hours after birth) or delayed (after 24 hours postpartum).
MSH

Hemorrhage defined as a blood loss in excess of 500 mL after vaginal delivery or more than 1000 mL after a cesarean delivery.
NCI

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cementování

The joining of objects by means of a cement (e.g., in fracture fixation, such as in hip arthroplasty for joining of the acetabular component to the femoral component). In dentistry, it is used for the process of attaching parts of a tooth or restorative material to a natural tooth or for the attaching of orthodontic bands to teeth by means of an adhesive.
MSH

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myorelaxancia centrální

A heterogeneous group of drugs used to produce muscle relaxation, excepting the neuromuscular blocking agents. They have their primary clinical and therapeutic uses in the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. They have been used also for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in MULTIPLE SCLEROSIS. (From Smith and Reynard, Textbook of Pharmacology, 1991, p358)
MSH

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elektroencefalografie – theta rytmus

Brain waves characterized by a frequency of 4-7 Hz, usually observed in the temporal lobes when the individual is awake, but relaxed and sleepy.
MSH

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hexosyltransferasy

Enzymes that catalyze the transfer of hexose groups. EC 2.4.1.-.
MSH

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praktolol

A beta-1 adrenergic antagonist that has been used in the emergency treatment of CARDIAC ARRYTHMIAS.
MSH

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cefamyciny

Naturally occurring family of beta-lactam cephalosporin-type antibiotics having a 7-methoxy group and possessing marked resistance to the action of beta-lactamases from gram-positive and gram-negative organisms.
MSH

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mykobakteriofágy

Viruses whose host is one or more Mycobacterium species. They include both temperate and virulent types.
MSH

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thiogalaktosidy

Galactosides in which the oxygen atom linking the sugar and aglycone is replaced by a sulfur atom.
MSH

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histamin

An amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.
MSH

depressor amine derived by enzymatic decarboxylation of histidine, present in the secretory granules of mast cells; a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.
CSP

a chemical substance in the body that produces allergic reactions
CHV

A substance that has many effects in the body. It is released from some types of white blood cells during allergic reactions. It causes small blood vessels to dilate (widen) and become leaky, which can cause tissues to swell. It also causes smooth muscles to contract, gastric acid to be made, and the heart rate to increase. Histamine is used in tests for allergies, asthma, and gastric acid secretion. It is a type of neurotransmitter.
NCI

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těhotenství – komplikace nádorové

The co-occurrence of pregnancy and NEOPLASMS. The neoplastic disease may precede or follow FERTILIZATION.
MSH

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Cerebrale pedunkel/ pedunculus cerebri

The cerebral crus is the most anterior portion of the midbrain which consists of a massive band of nerve fibers originating primarily from the cerebral cortex.
FMA

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myelitida z příčné léze

Inflammation of a transverse portion of the spinal cord characterized by acute or subacute segmental demyelination or necrosis. The condition may occur sporadically, follow an infection or vaccination, or present as a paraneoplastic syndrome (see also ENCEPHALOMYELITIS, ACUTE DISSEMINATED). Clinical manifestations include motor weakness, sensory loss, and incontinence. (Adams et al., Principles of Neurology, 6th ed, pp1242-6)
MSH

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hrudní chirurgie

A surgical specialty concerned with diagnosis and treatment of disorders of the heart, lungs, and esophagus. Two major types of thoracic surgery are classified as pulmonary and cardiovascular.
MSH

A branch of medicine dealing with the use of surgery to treat diseases of the chest and lungs. (On-line Medical Dictionary)
NCI

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Histone H4

Histone H4 is a core subunit of the eukaryotic nucleosome complex. Histones are basic nuclear proteins responsible for the nucleosome structure of chromatin. Repeating nucleosome units contain two molecules each of Histones H2A, H2B, H3, and H4 that form an octamer complex around which approximately 146 base pairs of DNA is wrapped. The nucleosome interacts with DNA between nucleosome units in mediating chromatin compaction into higher order structures. (Entrez Gene)
NCI

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předsudek

A preconceived judgment made without adequate evidence and not easily alterable by presentation of contrary evidence.
MSH

attitude or opinion which predisposes an individual to make a preconceived judgment prior to objective evaluation; frequently an irrational attitude of hostility directed against an individual, group, or race or their supposed characteristics; do not confuse with BIAS.
CSP

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ZERBIZITISA/GARONDOKO EROSIO/UMONTZI LEPOKO BESTE ERITASUN

deviation from or interruption of the normal structure or function of the cervix.
CSP

The cervix is the lower part of the uterus, the place where a baby grows during pregnancy. The cervix has a small opening that expands during childbirth. It also allows menstrual blood to leave a woman`s body.

Your healthcare provider may perform a Pap test during your health checkup to look for changes to the cells of the cervix, including cervical cancer. Other problems with the cervix include:

  • Cervicitis: inflammation of the cervix
  • Cervical incompetence: widening of the cervical opening during pregnancy long before the baby is due
  • Cervical polyps and cysts: abnormal growths on the cervix


MEDLINEPLUS

Pathological processes of the UTERINE CERVIX.
MSH

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myosin – těžké řetězce

The larger subunits of MYOSINS. The heavy chains have a molecular weight of about 230 kDa and each heavy chain is usually associated with a dissimilar pair of MYOSIN LIGHT CHAINS.
MSH

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kyselina 1-karboxyglutamová

Found in various tissues, particularly in four blood-clotting proteins including prothrombin, in kidney protein, in bone protein, and in the protein present in various ectopic calcifications.
MSH

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HLA-B8 antigen

A specific HLA-B surface antigen subtype. Members of this subtype contain alpha chains that are encoded by the HLA-B*08 allele family.
MSH

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priapismus

A prolonged painful erection that may lasts hours and is not associated with sexual activity. It is seen in patients with SICKLE CELL ANEMIA, advanced malignancy, spinal trauma; and certain drug treatments.
MSH

Persistent and usually painful erection that lasts for at least four hours, in the absence of physical or psychological stimulation. It may be caused by hematologic disorders including sickle cell disease and leukemia, spinal cord injuries, and medications.
NCI

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