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arachidonát-5-lipoxygenasa

An enzyme that catalyzes the oxidation of arachidonic acid to yield 5-hydroperoxyarachidonate (5-HPETE) which is rapidly converted by a peroxidase to 5-hydroxy-6,8,11,14-eicosatetraenoate (5-HETE). The 5-hydroperoxides are preferentially formed in leukocytes.
MSH

Arachidonate 5-lipoxygenase protein (674 aa, ~78 kDa) is encoded by the human ALOX5 gene. This protein plays a role in the synthesis of leukotrienes from arachidonic acid; thus, it mediates both inflammation and allergen responses.
NCI

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myosin – těžké řetězce

The larger subunits of MYOSINS. The heavy chains have a molecular weight of about 230 kDa and each heavy chain is usually associated with a dissimilar pair of MYOSIN LIGHT CHAINS.
MSH

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ornithindekarboxylasa

A pyridoxal-phosphate protein, believed to be the rate-limiting compound in the biosynthesis of polyamines. It catalyzes the decarboxylation of ornithine to form putrescine, which is then linked to a propylamine moiety of decarboxylated S-adenosylmethionine to form spermidine. EC 4.1.1.17.
MSH

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HLA-B8 antigen

A specific HLA-B surface antigen subtype. Members of this subtype contain alpha chains that are encoded by the HLA-B*08 allele family.
MSH

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deferoxamin

Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
MSH

natural product isolated from Streptomyces pilosus; it forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
CSP

An iron-chelating agent that removes iron from tumors by inhibiting DNA synthesis and causing cancer cell death. It is used in conjunction with other anticancer agents in pediatric neuroblastoma therapy.
NCI

An iron-chelating agent that binds free iron in a stable complex, preventing it from engaging in chemical reactions. Deferoxamine chelates iron from intra-lysosomal ferritin and siderin forming ferrioxamine, a water-soluble chelate excreted by the kidneys and in the feces via the bile. This agent does not readily bind iron from transferrin, hemoglobin, myoglobin or cytochrome. (NCI04)
NCI

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mazové žlázy

Small, sacculated organs found within the DERMIS. Each gland has a single duct that emerges from a cluster of oval alveoli. Each alveolus consists of a transparent BASEMENT MEMBRANE enclosing epithelial cells. The ducts from most sebaceous glands open into a HAIR FOLLICLE, but some open on the general surface of the SKIN. Sebaceous glands secrete SEBUM.
MSH

small, sacculated organs found within the dermis which secrete sebum; ducts from most sebaceous glands open into a hair follicle but some open on the general surface of the skin.
CSP

Small glands located within the epidermis, and associated with the hair follicle, that produce and secrete an oily substance that lubricates the skin and hair.
NCI

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kyselina argininjantarová

This amino acid is formed during the urea cycle from citrulline, aspartate and ATP. This reaction is catalyzed by argininosuccinic acid synthetase.
MSH

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ipratropium

A muscarinic antagonist structurally related to ATROPINE but often considered safer and more effective for inhalation use. It is used for various bronchial disorders, in rhinitis, and as an antiarrhythmic.
MSH

A synthetic derivative of the alkaloid atropine with anticholinergic properties. Ipratropium antagonizes the actions of acetylcholine at parasympathetic postganglionic effector cell junctions. When inhaled, ipratropium binds competitively to cholinergic receptors in the bronchial smooth muscle thereby blocking the bronchoconstrictor actions of the acetylcholine (Ach) mediated vagal impulses. Inhibition of the vagal tone leads to dilation of the large central airways resulting in bronchodilation.
NCI

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osmium

Osmium. A very hard, gray, toxic, and nearly infusible metal element, atomic number 76, atomic weight 190.2, symbol Os. (From Dorland, 28th ed)
MSH

very hard, gray, toxic and nearly infusible metal; atomic number 76, symbol Os.
CSP

An element with atomic symbol Os, atomic number 76, and atomic weight 190.23.
NCI

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Holtzmanův test inkoustové skvrny

Personality evaluation based on the scoring of several variables as a result of the subject`s responses in perceiving 47 inkblot plates.
MSH

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demekolcin

An alkaloid isolated from Colchicum autumnale L. and used as an antineoplastic.
MSH

A colchicine analog with potential antimitotic and antineoplastic activities. Demecolcine acid binds to the colchicine-binding site of tubulin, inhibiting its polymerization into microtubules, causing cell cycle arrest at metaphase and preventing cell division.
NCI

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jednotky samopéče

Rooms in health care facilities for patients who require a minimal level of care.
MSH

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arteriografie

A procedure to x-ray arteries. The arteries can be seen because of an injection of a dye that outlines the vessels on an x-ray.
NCI

The X-ray examination of the arterial blood vessels.
NCI

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kyselina nalidixová

A synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA GYRASE.
MSH

A synthetic quinolone and antibacterial agent with urinary tract antiseptic activity. Nalidixic acid concentrates in the renal tubules and bladder and exerts its local antibacterial actions by interference of DNA gyrase activity, thereby inhibiting DNA synthesis during bacterial replication in a dose-dependent manner. Nalidixic acid is active against most gram-negative organisms that cause urinary tract infections.
NCI

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osteomyelitida

inflammation of the bone marrow and adjacent bone caused by a pyogenic organism; it may remain localized or may spread through the bone to involve the marrow, cortex, cancellous tissue, and periosteum.
CSP

Inflammation of the bone caused by an infection, which may spread to the bone marrow and tissues near the bone. Osteomyelitis can cause severe pain in the infected bone. If it is not treated, it can kill bone tissue.
NCI

An acute or chronic inflammation of the bone and its structures due to infection with pyogenic bacteria.
NCI

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Xiphosura

An arthropod subclass (Xiphosura) comprising the North American (Limulus) and Asiatic (Tachypleus) genera of horseshoe crabs.
MSH

only living member of the class Malacostraca; not a true crab; body has a broadly oval shell and a long slender tail; lives in a marine environment.
CSP

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zubní kavita – preparace

An operation in which carious material is removed from teeth and biomechanically correct forms are established in the teeth to receive and retain restorations. A constant requirement is provision for prevention of failure of the restoration through recurrence of decay or inadequate resistance to applied stresses. (Boucher`s Clinical Dental Terminology, 4th ed, p239-40)
MSH

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septikémie

systemic disease associated with presence and persistance of pathogenic microorganisms or their toxins in the blood.
CSP

Systemic disease associated with the presence of pathogenic microorganisms or their toxins in the blood.
MSH

Sepsis is a life-threatening illness. Your body`s response to a bacterial infection usually causes it. Your immune system goes into overdrive, overwhelming normal processes in your blood. The result is that small blood clots form, blocking blood flow to vital organs. This can lead to organ failure. Babies, old people and those with weakened immune systems are most likely to get sepsis. But even healthy people can become deathly ill from it. A quick diagnosis can be crucial, because one third of people who get sepsis die from it.

Sepsis is usually treated in a hospital intensive care unit (ICU). IV antibiotics and fluids may be given to try to knock out the infection and to keep blood pressure from dropping too low. Patients may also need respirators to help them breathe.


MEDLINEPLUS

A disorder characterized by the presence of pathogenic microorganisms in the blood stream that cause a rapidly progressing systemic reaction that may lead to shock.
NCI

Disease caused by the spread of bacteria and their toxins in the bloodstream.
NCI

The presence of pathogenic microorganisms in the blood stream causing a rapidly progressing systemic reaction that may lead to shock. Symptoms include fever, chills, tachycardia, and increased respiratory rate. It is a medical emergency that requires urgent medical attention.
NCI

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arylsulfonany

Organic sulfonic acid esters or salts which contain an aromatic hydrocarbon radical.
MSH

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nos – obstrukce

Any hindrance to the passage of air into and out of the nose. The obstruction may be unilateral or bilateral, and may involve any part of the NASAL CAVITY.
MSH

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pacienti ambulantní

Persons who receive ambulatory care at an outpatient department or clinic without room and board being provided.
MSH

A patient who visits a health care facility for diagnosis or treatment without spending the night. Sometimes called a day patient.
NCI

A patient who comes to a healthcare facility for diagnosis or treatment but is not admitted for an overnight stay.
NCI

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nemocnice vojenské

Hospitals which provide care for the military personnel and usually for their dependents.
MSH

A health care facility operated by the Department of Defense.


HL7V3.0

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zubní plak

A film that attaches to teeth, often causing DENTAL CARIES and GINGIVITIS. It is composed of MUCINS, secreted from salivary glands, and microorganisms.
MSH

film that attaches to teeth, often causing dental caries and gingivitis; composed of mucins, secreted from salivary glands, and microorganisms.
CSP

A biofilm that contains numerous microorganisms that adheres to the teeth.
NCI

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sérový baktericidní test

Method of measuring the bactericidal activity contained in a patient`s serum as a result of antimicrobial therapy. It is used to monitor the therapy in BACTERIAL ENDOCARDITIS; OSTEOMYELITIS and other serious bacterial infections. As commonly performed, the test is a variation of the broth dilution test. This test needs to be distinguished from testing of the naturally occurring BLOOD BACTERICIDAL ACTIVITY.
MSH

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aspartátová amoniaklyasa

An enzyme that catalyzes the conversion of aspartic acid to ammonia and fumaric acid in plants and some microorganisms. EC 4.3.1.1.
MSH

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utonutí neúplné

Non-fatal immersion or submersion in water. The subject is resuscitable.
MSH

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oxazolon

Immunologic adjuvant and sensitizing agent.
MSH

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Deltaretrovirus – infekce

Infections caused by the HTLV or BLV deltaretroviruses. They include human T-cell leukemia-lymphoma (LEUKEMIA-LYMPHOMA, T-CELL, ACUTE, HTLV-I-ASSOCIATED).
MSH

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dentin sekundární

Dentin formed by normal pulp after completion of root end formation.
MSH

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pohlavní předvýběr

Methods for controlling genetic SEX of offspring.
MSH

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