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leucin

An essential branched-chain amino acid important for hemoglobin formation.
MSH

essential branched-chain amino acid important for hemoglobin formation.
CSP

Amino acid with side chain -CH2CH(CH3)2.
NCI

One of nine essential amino acids in humans (provided by food), Leucine is important for protein synthesis and many metabolic functions. Leucine contributes to regulation of blood-sugar levels; growth and repair of muscle and bone tissue; growth hormone production; and wound healing. Leucine also prevents breakdown of muscle proteins after trauma or severe stress and may be beneficial for individuals with phenylketonuria. Leucine is available in many foods and deficiency is rare. (NCI04)
NCI

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Bahamy

A chain of islands, cays, and reefs in the West Indies, lying southeast of Florida and north of Cuba. It is an independent state, called also the Commonwealth of the Bahamas or the Bahama Islands. The name likely represents the local name Guanahani, itself of uncertain origin. (From Webster`s New Geographical Dictionary, 1988, p106 & Room, Brewer`s Dictionary of Names, 1992, p45)
MSH

A chain of islands in the North Atlantic Ocean, southeast of Florida. (NCI)
NCI

A chain of islands in the North Atlantic Ocean, southeast of Florida. (CIA World Factbook 2002)
NCI

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hasicí látky

Materials applied to fabrics, bedding, furniture, plastics, etc. to retard their burning; many may leach out and cause allergies or other harm.
MSH

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steroid-21-hydroxylasa

An adrenal microsomal cytochrome P450 enzyme that catalyzes the 21-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP21 gene, converts progesterones to precursors of adrenal steroid hormones (CORTICOSTERONE; HYDROCORTISONE). Defects in CYP21 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL).
MSH

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fenoxybenzamin

An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.
MSH

A synthetic, dibenzamine alpha adrenergic antagonist with antihypertensive and vasodilatory properties. Phenoxybenzamine non-selectively and irreversibly blocks the postsynaptic alpha-adrenergic receptor in smooth muscle, thereby preventing vasoconstriction, relieving vasospasms, and decreasing peripheral resistance. Reflex tachycardia may occur and may be enhanced by blockade of alpha-2 receptors which enhances norepinephrine release. Phenoxybenzamine is reasonably anticipated to be a human carcinogen.
NCI

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Dientamoeba

A genus of minute EUKARYOTES that are characterized by the preponderance of binucleate over uninucleate forms, the presence of several distinct granules in the karyosome, and the lack of a cystic stage. It is parasitic in the large intestine of humans and certain monkeys.
MSH

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leukémie pre-B-buněčná

A leukemia/lymphoma found predominately in children and adolescents and characterized by a high number of lymphoblasts and solid tumor lesions. Frequent sites involve LYMPH NODES, skin, and bones. It most commonly presents as leukemia.
MSH

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Bartterův syndrom

transmitted as an autosomal recessive trait; characterized by hypertrophy and hyperplasia of the juxtaglomerular cells, and increased concentrations of renin, angiotensin II, and aldosterone in the absence of edema and hypertension.
CSP

A rare inherited syndrome characterized by juxtaglomerular cell hyperplasia, hyperaldosteronism, hypokalemia, and alkalosis. Patients have high levels of plasma renin concentration which is not associated with hypertension.
NCI

A group of disorders caused by defective salt reabsorption in the ascending LOOP OF HENLE. It is characterized by severe salt-wasting, HYPOKALEMIA; HYPERCALCIURIA; metabolic ALKALOSIS, and hyper-reninemic HYPERALDOSTERONISM without HYPERTENSION. There are several subtypes including ones due to mutations in the renal specific SODIUM-POTASSIUM-CHLORIDE SYMPORTERS.
MSH

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fludrokortison

A synthetic mineralocorticoid with anti-inflammatory activity.
MSH

A synthetic corticosteroid. It is used to replace steroid hormones normally produced by the adrenal gland.
NCI

A synthetic corticosteroid with antiinflammatory and antiallergic properties. Fludrocortisone is a mineralocorticoid receptor and glucocorticoid receptor agonist that binds to cytoplasmic receptors, translocates to the nucleus and subsequently initiates the transcription of glucocorticoid-responsive genes such as lipocortins to inhibit phospholipase A2. This prevents the release of arachidonic acid, a precursor to prostaglandins and leukotrienes, both important mediators in the pro-inflammatory response mechanism. In addition, this agent exerts its mineralocorticoid effect on the distal tubules and collecting ducts of the kidney by inducing permease, an enzyme that regulates Na+ permeability in cells, thereby enhancing Na+ reabsorption and water retention as well as increasing K+, H+ excretion.
NCI

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stomatologické nemoci

General or unspecified diseases of the stomatognathic system, comprising the mouth, teeth, jaws, and pharynx.
MSH

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filadelfský chromozóm

An aberrant form of human CHROMOSOME 22 characterized by translocation of the distal end of chromosome 9 from 9q34, to the long arm of chromosome 22 at 22q11. It is present in the bone marrow cells of 80 to 90 per cent of patients with chronic myelocytic leukemia (LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE).
MSH

An abnormality of chromosome 22 in which part of chromosome 9 is transferred to it. Bone marrow cells that contain the Philadelphia chromosome are often found in chronic myelogenous leukemia.
NCI

A translocation between chromosomes 9 and 22. It is the hallmark for chronic myelogenous leukemia (CML).
NCI

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rozšiřování inovací

The broad dissemination of new ideas, procedures, techniques, materials, and devices and the degree to which these are accepted and used.
MSH

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leupeptiny

A group of acylated oligopeptides produced by Actinomycetes that function as protease inhibitors. They have been known to inhibit to varying degrees trypsin, plasmin, KALLIKREINS, papain and the cathepsins.
MSH

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přeměna lůžek

The reallocation of beds from one type of care service to another, as in converting acute care beds to long term care beds.
MSH

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fluorometrie

An analytical method for detecting and measuring FLUORESCENCE in compounds or targets such as cells, proteins, or nucleotides, or targets previously labeled with FLUORESCENCE AGENTS.
MSH

the measurement of fluorescence.
CSP

An analytical method that utilizes ultraviolet light to excite the sample and detects the fluorescence emitted during the return of the sample to its ground state.
NCI

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stres mechanický

A purely physical condition which exists within any material because of strain or deformation by external forces or by non-uniform thermal expansion; expressed quantitatively in units of force per unit area.
MSH

physical condition which exists within any material because of strain or deformation by external forces or by non-uniform thermal expansion.
CSP

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fosfátacetyltransferasa

An enzyme that catalyzes the synthesis of acetylphosphate from acetyl-CoA and inorganic phosphate. Acetylphosphate serves as a high-energy phosphate compound. EC 2.3.1.8.
MSH

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dihydropteroátsynthasa

An enzyme that catalyzes the formation of dihydropteroate from p-aminobenzoic acid and dihydropteridine-hydroxymethyl-pyrophosphate. EC 2.5.1.15.
MSH

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Blíže neurčený lichen

skin disease caused by lichen fungus
CHV

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Bender-Gestalt test

A psychological test consisting of nine geometric designs on cards. The subject is asked to redraw them from memory after each one is presented individually.
MSH

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následné studie

Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.
MSH

Study in which persons exposed to risk or given a designated preventive or therapeutic regimen are observed over a period or at intervals to determine the outcome of the exposure or regimen. (On-line Medical Dictionary)
NCI

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Sturgeův-Weberův syndrom

A non-inherited congenital condition with vascular and neurological abnormalities. It is characterized by facial vascular nevi (PORT-WINE STAIN), and capillary angiomatosis of intracranial membranes (MENINGES; CHOROID). Neurological features include EPILEPSY; cognitive deficits; GLAUCOMA; and visual defects.
MSH

A rare, congenital disorder that affects the brain, skin, and eyes. Abnormal blood vessel growth occurs in the trigeminal nerve in the face and the meninges (covering) of the brain. This abnormal growth causes red or purple skin discoloration (sometimes called a port wine stain), usually on one side of the face, and can also cause seizures, learning disabilities, and glaucoma.
NCI

A congenital disorder characterized by the presence of a port-wine nevus birthmark on one or both sides of the face. Additional clinical manifestations may include seizures, leptomenigeal angiomas, glaucoma, progressive hemiparesis and cognitive deficits.
NCI

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fosfolipasy

A class of enzymes that catalyze the hydrolysis of phosphoglycerides or glycerophosphatidates. EC 3.1.-.
MSH

Enzymes that catalyze the cleavage of a phospholipid molecule by the addition of water, thereby causing hydrolysis. The classification is based on the specificity of the bond cleaved. Hydrolytic activity initiates signaling cascades in the cell.
NCI

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dimethylpolysiloxany

Silicone polymers which consist of silicon atoms substituted with methyl groups and linked by oxygen atoms. They comprise a series of biocompatible materials used as liquids, gels or solids; as film for artificial membranes, gels for implants, and liquids for drug vehicles; and as antifoaming agents.
MSH

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nervus lingualis

A sensory branch of the MANDIBULAR NERVE, which is part of the trigeminal (5th cranial) nerve. The lingual nerve carries general afferent fibers from the anterior two-thirds of the tongue, the floor of the mouth, and the mandibular gingivae.
MSH

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benzoin

A white crystalline compound prepared by condensation of benzaldehyde in potassium cyanide and used in organic syntheses. This should not be confused with benzoin gum from STYRAX.
MSH

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noha – dermatózy

Skin diseases of the foot, general or unspecified.
MSH

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benzoylcholin

The benzoic acid ester of choline.
MSH

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předloktí

The structure on the upper limb, between the elbow and the wrist. (NCI)
NCI

The structure on the upper limb, between the elbow and the wrist.
NCI

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sukcinátdehydrogenasa

A flavoprotein containing oxidoreductase that catalyzes the dehydrogenation of SUCCINATE to fumarate. In most eukaryotic organisms this enzyme is a component of mitochondrial electron transport complex II.
MSH

creates a double bond between the 2 middle carbons of succinate to form fumarate.
CSP

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