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ceftazidim

Semisynthetic, broad-spectrum antibacterial derived from CEPHALORIDINE and used especially for Pseudomonas and other gram-negative infections in debilitated patients.
MSH

A beta-lactam, third-generation cephalosporin antibiotic with bactericidal activity. Ceftazidime binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. PBPs participate in the terminal stages of assembling the bacterial cell wall, and in reshaping the cell wall during cell division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis. Compared to the second and first generation cephalosporins, ceftazidime is more active against gram-negative bacteria and less active against gram-positive bacteria. Ceftazidine also crosses the blood-brain barrier and reaches therapeutic concentrations in the central nervous system (CNS).
NCI

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růstový faktor odvozený z trombocytů

Mitogenic peptide growth hormone carried in the alpha-granules of platelets. It is released when platelets adhere to traumatized tissues. Connective tissue cells near the traumatized region respond by initiating the process of replication.
MSH

mitogenic peptide growth hormone carried in the alpha-granules of platelets; released when platelets adhere to traumatized tissues; connective tissue cells near the traumatized region respond by initiating the process of replication.
CSP

A family of molecules released from platelets (tiny pieces of cells that are found in the blood and that help the blood clot). Forms of PDGF help to heal wounds and to repair damage to blood vessel walls. They also help blood vessels grow.
NCI

Expressed in platelets, human Platelet-Derived Growth Factor (PDGF/VEGF Family) is a mitogenic factor for mesenchymal cells characterized by a motif of eight cysteines and released upon wounding to stimulate adjacent cell growth. PDGF can exist as antiparallel disulfide-linked homodimers (PDGFA, PDGFB) or heterodimers (PDGFA/PDGFB) that bind to PDGF receptor and elicit a variety of cellular responses. A and B homodimers are implicated in transformation processes. (NCI)
NCI

The major mitogen in serum for growth in culture of cells of connective tissue origin. It consists of 2 different but homologous polypeptides A and B (~30,000 D) linked by disulphide bonds. The B chain is almost identical in sequence to p28sis, the transforming protein of simian sarcoma virus.
NCI

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mitobronitol

Brominated analog of MANNITOL which is an antineoplastic agent appearing to act as an alkylating agent.
MSH

A brominated analog of mannitol with potential antineoplastic activity. Mitobronitol most likely acts through alkylation via derived epoxide groups.
NCI

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síňová ektopická tachykardie

Abnormally rapid heartbeats originating from one or more automatic foci (nonsinus pacemakers) in the HEART ATRIUM but away from the SINOATRIAL NODE. Unlike the reentry mechanism, automatic tachycardia speeds up and slows down gradually. The episode is characterized by a HEART RATE between 135 to less than 200 beats per minute and lasting 30 seconds or longer.
MSH

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hemaglutininy virové

Specific hemagglutinin subtypes encoded by VIRUSES.
MSH

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lokomoce buněk

ability of cells to move from one location to another.
CSP

Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another. [GOC:dgh, GOC:dph, GOC:isa_complete, GOC:mlg]
GO

Cell Motility consists of active translocation of a whole cell, or cell body, from one site to another; distinct from cell motion that involves movement of cell processes (e.g., axons, microvilli, etc.). (NCI)
NCI

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pneumoencefalografie

Radiographic visualization of the cerebral ventricles by injection of air or other gas.
MSH

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modely molekulární

Models used experimentally or theoretically to study molecular shape, electronic properties, or interactions; includes analogous molecules, computer-generated graphics, and mechanical structures.
NCI

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Tarsiidae

The single family of PRIMATES in the infraorder TARSII, suborder HAPLORHINI. It is comprised of one genus, Tarsius, that inhabits southern Sumatra, Borneo, Sulawesi, and the Philippines.
MSH

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hemerythrin

A non-heme iron protein consisting of eight apparently identical subunits each containing 2 iron atoms. It binds one molecule of oxygen per pair of iron atoms and functions as a respiratory protein.
MSH

protein found in the blood of earthworms which imparts its red color.
CSP

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centrální nervový systém – látky depresorické

A very loosely defined group of drugs that tend to reduce the activity of the central nervous system. The major groups included here are ethyl alcohol, anesthetics, hypnotics and sedatives, narcotics, and tranquilizing agents (antipsychotics and antianxiety agents).
MSH

loosely defined group of drugs that tend to reduce the activity of the central nervous system.
CSP

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Poissonovo rozdělení

A distribution function used to describe the occurrence of rare events or to describe the sampling distribution of isolated counts in a continuum of time or space.
MSH

A distribution function used to describe the occurrence of rare events or to describe the sampling distribution of isolated counts in a continuum of time or space. This special probability distribution can apply to the number of discrete independent random events occurring in a given interval when knowing their average rate of occurrence over a very long interval. (Dr. Joseph A. Thie)
NCI

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monensin

An antiprotozoal agent produced by Streptomyces cinnamonensis. It exerts its effect during the development of first-generation trophozoites into first-generation schizonts within the intestinal epithelial cells. It does not interfere with hosts` development of acquired immunity to the majority of coccidial species. Monensin is a sodium and proton selective ionophore and is widely used as such in biochemical studies.
MSH

polyether ionophore produced by Streptomyces cinnamonensis; causes collapse of sodium and potassium gradients at the plasma membrane, blocks intracelluar protein transport, and has broad antimicrobial efficacy; also has vasodilatory-antihypertensive properties.
CSP

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technologie nákladná

Advanced technology that is costly, requires highly skilled personnel, and is unique in its particular application. Includes innovative, specialized medical/surgical procedures as well as advanced diagnostic and therapeutic equipment.
MSH

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hemoglobinopatie

A group of inherited disorders characterized by structural alterations within the hemoglobin molecule.
MSH

group of inherited disorders characterized by structural alterations within the hemoglobin molecule.
CSP

An inherited disorder characterized by structural alterations of a globin chain within the hemoglobin molecule.
NCI

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mozeček – kůra

The superficial gray matter of the cerebellum. It consists of two main layers, the stratum moleculare and the stratum granulosum. (Dorland, 28th ed)
MSH

superficial gray matter of the cerebellum; consists of two main layers, the stratum moleculare and the stratum granulosum.
CSP

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Polychaeta

A class of marine annelids including sandworms, tube worms, clamworms, and fire worms. It includes also the genus Myxicola infundibulum.
MSH

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morálka – vývoj

The process by which individuals internalize standards of right and wrong conduct.
MSH

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syndrom temporomandibulárního kloubu

symptom complex consisting of partial deafness, stuffy sensation in the ears, tinnitus, pain, muscle tenderness, clicking in the joint, and limitation or alteration of mandibular movement; symptoms are subjective and manifested primarily in the masticatory muscles rather than the temporomandibular joint itself; etiologic factors are uncertain but include occlusal dysharmony and psychophysiologic factors.
CSP

A symptom complex consisting of pain, muscle tenderness, clicking in the joint, and limitation or alteration of mandibular movement. The symptoms are subjective and manifested primarily in the masticatory muscles rather than the temporomandibular joint itself. Etiologic factors are uncertain but include occlusal dysharmony and psychophysiologic factors.
MSH

The temporomandibular joint (TMJ) connects your jaw to the side of your head. When it works well, it enables you to talk, chew and yawn. For people with TMJ dysfunction, problems with the joint and muscles around it may cause

  • Pain that travels through the face, jaw or neck
  • Stiff jaw muscles
  • Limited movement or locking of the jaw
  • Painful clicking or popping in the jaw
  • A change in the way the upper and lower teeth fit together

Jaw pain may go away with little or no treatment. Treatment may include simple things you can do yourself, such as eating soft foods or applying ice packs. It may also include pain medicines or devices to insert in your mouth. In rare cases, you might need surgery.

NIH: National Institute of Dental and Craniofacial Research


MEDLINEPLUS

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hemostáza

The process which spontaneously arrests the flow of BLOOD from vessels carrying blood under pressure. It is accomplished by contraction of the vessels, adhesion and aggregation of formed blood elements (eg. ERYTHROCYTE AGGREGATION), and the process of BLOOD COAGULATION.
MSH

process of arresting blood flow or bleeding, either physiologically by vasoconstriction and coagulation or by mechanical or surgical means.
CSP

The arrest of bleeding, either by the natural processes of vasoconstriction and coagulation or by surgical means.
NCI

The stopping of bleeding (loss of body fluid) or the arrest of the circulation to an organ or part. [ISBN:0198506732 “Oxford Dictionary of Biochemistry and Molecular Biology”]
GO

The arrest of bleeding, either by the physiological properties of vasoconstriction and coagulation or by surgical means.
NCI

body function that stops bleeding by coagulating blood and constricting blood vessel
CHV

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mozkomíšní mok – tlak

Manometric pressure of the CEREBROSPINAL FLUID as measured by lumbar, cerebroventricular, or cisternal puncture. Within the cranial cavity it is called INTRACRANIAL PRESSURE.
MSH

manometric pressure of the cerebrospinal fluid as measured by lumbar, cerebroventricular, or cisternal puncture.
CSP

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kyseliny polymethakrylové

Poly-2-methylpropenoic acids. Used in the manufacture of methacrylate resins and plastics in the form of pellets and granules, as absorbent for biological materials and as filters; also as biological membranes and as hydrogens. Synonyms: methylacrylate polymer; poly(methylacrylate); acrylic acid methyl ester polymer.
MSH

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kinetózy

Disorder caused by motion, as sea sickness, train sickness, car sickness, air sickness, or SPACE MOTION SICKNESS. It may include nausea, vomiting and dizziness.
MSH

Motion sickness is a common problem in people traveling by car, train, airplanes and especially boats. Motion sickness can start suddenly, with a queasy feeling and cold sweats. It can then lead to dizziness and nausea and vomiting.

Your brain senses movement by getting signals from your inner ears, eyes, muscles and joints. When it gets signals that do not match, you can get motion sickness. For example, down below on a boat, your inner ear senses motion, but your eyes cannot tell you are moving.

Where you sit can make a difference. The front seat of a car, forward cars of a train, upper deck on a boat or wing seats in a plane may give you a smoother ride. Looking out into the distance – instead of trying to read or look at something in the vehicle – can also help.

Centers for Disease Control and Prevention


MEDLINEPLUS

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testikulární hormony

Hormones produced in the testis.
MSH

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virus hepatitidy kachen

Unassigned species, in the family PICORNAVIRIDAE, causing high mortality in ducklings 3 days to 3 weeks old.
MSH

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Cestoda – infekce

Infections with true tapeworms of the helminth subclass CESTODA.
MSH

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vícenenasycené mastné kyseliny

fatty acid containing more than one double bond (C=C). The essential fatty acids omega-3 and omega-6 are polyunsaturated fatty acids (PUFAs) that contain 2 or more cis double bonds. Dietary intake of some PUFAs may have beneficial effects on blood pressure, serum lipds, and inflammation. Some PUFAs, such as omega-3 PUFAs, may have antineoplastic or chemopreventive activities.
NCI

A class of dietary fatty acids containing two or more double bonds.
NCI

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melanocyty stimulující hormony

peptide hormones secreted by the intermediate lobe of the pituitary that stimulate melanin release and dispersal; also found in the brain where they are presumed to play a signaling role.
CSP

Peptides with the ability to stimulate pigmented cells MELANOCYTES in mammals and MELANOPHORES in lower vertebrates. By stimulating the synthesis and distribution of MELANIN in these pigmented cells, they increase coloration of skin and other tissue. MSHs, derived from pro-opiomelanocortin (POMC), are produced by MELANOTROPHS in the INTERMEDIATE LOBE OF PITUITARY; CORTICOTROPHS in the ANTERIOR LOBE OF PITUITARY, and the hypothalamic neurons in the ARCUATE NUCLEUS.
MSH

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Tetrahymena pyriformis

A species of ciliate protozoa used extensively in genetic research.
MSH

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HERNIA INGINALA

An abdominal hernia with an external bulge in the GROIN region. It can be classified by the location of herniation. Indirect inguinal hernias occur through the internal inguinal ring. Direct inguinal hernias occur through defects in the ABDOMINAL WALL (transversalis fascia) in Hesselbach`s triangle. The former type is commonly seen in children and young adults; the latter in adults.
MSH

The protrusion of a sac-like structure containing fibroadipose tissue through an abnormal opening in the inguinal region.
NCI

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