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kinetózy

Disorder caused by motion, as sea sickness, train sickness, car sickness, air sickness, or SPACE MOTION SICKNESS. It may include nausea, vomiting and dizziness.
MSH

Motion sickness is a common problem in people traveling by car, train, airplanes and especially boats. Motion sickness can start suddenly, with a queasy feeling and cold sweats. It can then lead to dizziness and nausea and vomiting.

Your brain senses movement by getting signals from your inner ears, eyes, muscles and joints. When it gets signals that do not match, you can get motion sickness. For example, down below on a boat, your inner ear senses motion, but your eyes cannot tell you are moving.

Where you sit can make a difference. The front seat of a car, forward cars of a train, upper deck on a boat or wing seats in a plane may give you a smoother ride. Looking out into the distance – instead of trying to read or look at something in the vehicle – can also help.

Centers for Disease Control and Prevention


MEDLINEPLUS

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virus hepatitidy kachen

Unassigned species, in the family PICORNAVIRIDAE, causing high mortality in ducklings 3 days to 3 weeks old.
MSH

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cykloserin

Antibiotic substance produced by Streptomyces garyphalus.
MSH

An analogue of the amino acid D-alanine with broad-spectrum antibiotic and glycinergic activities. D-cycloserine interferes with bacterial cell wall synthesis by competitively inhibiting two enzymes, L-alanine racemase and D-alanine:D-alanine ligase, thereby impairing peptidoglycan formation necessary for bacterial cell wall synthesis. This agent may be bactericidal or bacteriostatic, depending on its concentration at the infection site and the susceptibility of the organism. In addition, D-cycloserine is an excitatory amino acid and partial agonist at the glycine binding site of the NMDA receptor in the central nervous system (CNS); binding to the central NMDA receptor may result in amelioration of neuropathic pain.
NCI

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alanintransaminasa

An enzyme that catalyzes the conversion of L-alanine and 2-oxoglutarate to pyruvate and L-glutamate. (From Enzyme Nomenclature, 1992) EC 2.6.1.2.
MSH

Expressed in liver, kidney, heart, fat, and skeletal muscle by glucocorticoid-induced human GPT Gene (Alanine Aminotransferase Family), 495-aa 54-kDa Glutamic-Pyruvate Transaminase is a homodimeric cytoplasmic pyridoxal phosphate-dependent enzyme involved in cellular nitrogen metabolism, amino acid metabolism, and liver gluconeogenesis. GPT mediates conversion of major intermediate metabolites, catalyzing reversible transamination between alanine and alpha-ketoglutarate to form pyruvate and glutamate. (NCI)
NCI

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antigeny diferenciační myelomonocytární

Surface antigens expressed on myeloid cells of the granulocyte-monocyte-histiocyte series during differentiation. Analysis of their reactivity in normal and malignant myelomonocytic cells is useful in identifying and classifying human leukemias and lymphomas.
MSH

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chinony

Hydrocarbon rings which contain two ketone moieties in any position. They can be substituted in any position except at the ketone groups.
MSH

benzene ring with 2 para keto groups.
CSP

A class of organic compounds with the base structure of quinone, an aromatic benzene molecule containing a double ketone functional group.
NCI

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melanocyty stimulující hormony

peptide hormones secreted by the intermediate lobe of the pituitary that stimulate melanin release and dispersal; also found in the brain where they are presumed to play a signaling role.
CSP

Peptides with the ability to stimulate pigmented cells MELANOCYTES in mammals and MELANOPHORES in lower vertebrates. By stimulating the synthesis and distribution of MELANIN in these pigmented cells, they increase coloration of skin and other tissue. MSHs, derived from pro-opiomelanocortin (POMC), are produced by MELANOTROPHS in the INTERMEDIATE LOBE OF PITUITARY; CORTICOTROPHS in the ANTERIOR LOBE OF PITUITARY, and the hypothalamic neurons in the ARCUATE NUCLEUS.
MSH

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HERNIA INGINALA

An abdominal hernia with an external bulge in the GROIN region. It can be classified by the location of herniation. Indirect inguinal hernias occur through the internal inguinal ring. Direct inguinal hernias occur through defects in the ABDOMINAL WALL (transversalis fascia) in Hesselbach`s triangle. The former type is commonly seen in children and young adults; the latter in adults.
MSH

The protrusion of a sac-like structure containing fibroadipose tissue through an abnormal opening in the inguinal region.
NCI

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cysteinové endopeptidasy

ENDOPEPTIDASES which have a cysteine involved in the catalytic process. This group of enzymes is inactivated by CYSTEINE PROTEINASE INHIBITORS such as CYSTATINS and SULFHYDRYL REAGENTS.
MSH

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aldehyddehydrogenasa

An enzyme that oxidizes an aldehyde in the presence of NAD+ and water to an acid and NADH. This enzyme was formerly classified as EC 1.1.1.70.
MSH

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antitumorózní látky fytogenní

Agents obtained from higher plants that have demonstrable cytostatic or antineoplastic activity.
MSH

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radikální krční disekce

A surgical procedure in which all the ipsilateral cervical lymph node groups of the neck, internal jugular vein, sternocleidomastoid muscle, spinal accessory nerve, and submandibular gland are removed.
NCI

A surgical operation for head and neck malignancies, most of which are squamous cell carcinomas. The neck is opened laterally, the majority of the sternocleidomastoid muscle is removed, as are the regional cervical lymph nodes, the jugular vein, the spinal accessory nerve, the submaxillary gland and most of the parotid gland. There are several modifications. (From Segen, Dictionary of Modern Medicine, 1992, p605)
MSH

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mumie

Bodies preserved either by the ancient Egyptian technique or due to chance under favorable climatic conditions.
MSH

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heterozygot

An individual having different alleles at one or more loci regarding a specific character.
MSH

having different alleles at one or more loci in homologous chromosome segments.
CSP

Having two different allelic forms of a gene, one inherited from each parent, on each of the two homologous chromosomes.
NCI

Occurs when the two alleles at a particular gene locus are different. A heterozygous genotype may include one normal allele and one mutation, or two different mutations. The latter is called a compound heterozygote.
NCI

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cytochromy b5

Cytochromes of the b group that are found bound to cytoplasmic side of ENDOPLASMIC RETICULUM. They serve as electron carrier proteins for a variety of membrane-bound OXYGENASES. They are reduced by the enzyme CYTOCHROME-B(5) REDUCTASE.
MSH

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alkylační látky

Highly reactive chemicals that introduce alkyl radicals into biologically active molecules and thereby prevent their proper functioning. Many are used as antineoplastic agents, but most are very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. They have also been used as components in poison gases.
MSH

chemical agent that can add alkyl groups (for example, ethyl or methyl groups) to another molecule; many mutagens act through alkylation.
CSP

A type of drug that is used in the treatment of cancer. It interferes with the cell`s DNA and inhibits cancer cell growth.
NCI

Agents that replace hydrogen atom(s) in biologically active molecules with alky radical(s), hindering proper function. Alkylating agents exhibit cytotoxic effects through the alkylation of DNA, resulting in strand cross-linking, ultimately inhibiting DNA replication and cell growth.
NCI

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anus – nádory

Tumors or cancer of the ANAL CANAL.
MSH

A benign or malignant neoplasm involving the anus.
NCI

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hygiena záření

Health concerns associated with the effects of radiation on the environment and on public and personal health.
MSH

the health effects of radiation; includes effects and hazards from environmental radiation fallout, occupational radiation, diagnostic or therapeutic radiological equipment or materials.
CSP

Studies focusing on the effects of radiation on the environment and on public and personal health.
NCI

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nervus musculocutaneus

A major nerve of the upper extremity. The fibers of the musculocutaneous nerve originate in the lower cervical spinal cord (usually C5 to C7), travel via the lateral cord of the brachial plexus, and supply sensory and motor innervation to the upper arm, elbow, and forearm.
MSH

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vysokofrekvenční ventilace

Ventilatory support system using frequencies from 60-900 cycles/min or more. Three types of systems have been distinguished on the basis of rates, volumes, and the system used. They are high frequency positive-pressure ventilation (HFPPV); HIGH-FREQUENCY JET VENTILATION; (HFJV); and high-frequency oscillation (HFO).
MSH

use this term only for respiratory therapy; do not confuse with HYPERPNEA.
CSP

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cytoplazmatická granula

Condensed areas of cellular material that may be bounded by a membrane.
MSH

insoluble nonmembranous particles found in cytoplasm.
CSP

Any small grainlike particle.
NCI

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Alouatta

A genus of the subfamily ALOUATTINAE, family ATELIDAE, inhabiting the forests of Central and South America. Howlers travel in groups and define their territories by howling accompanied by vigorously shaking and breaking branches.
MSH

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Brocova afázie

An aphasia characterized by impairment of expressive language (speech, writing, signs) and relative preservation of receptive language abilities (i.e., comprehension). This condition is caused by lesions of the motor association cortex in the frontal lobe (Broca`s area and adjacent cortical and white matter regions). The deficits range from almost complete muteness to a reduction in the fluency and rate of speech. CEREBROVASCULAR ACCIDENTS (in particular INFARCTION, MIDDLE CEREBRAL ARTERY) are a relatively common cause of this condition. (From Adams et al., Principles of Neurology, 6th ed, pp478-9)
MSH

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Ranidae

The family of true frogs of the order Anura. The family occurs worldwide except in Antarctica.
MSH

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Mycobacterium scrofulaceum

A non-tuberculous mycobacterium causing cervical lymphadenitis in children. It very rarely causes pulmonary disease, and is believed to be non-pathogenic in animals.
MSH

Any bacterial organism that can be assigned to the species Mycobacterium scrofulaceum.
NCI

A species of aerobic, Gram positive, rod shaped bacterium assigned to the phylum Actinobacteria. This species is acid fast, nonmotile, acid phosphatase and iron uptake negative and catalase, urease, pyrazinamidase and nicotinamidase positive. M. scrofulaceum is found in environmental sources such as house dust, soil, water, and sewage as well as food sources such as raw milk, and it is frequently associated with cervical adenitis in children.
NCI

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histidin-tRNA-ligasa

An enzyme that activates histidine with its specific transfer RNA. EC 6.1.1.21.
MSH

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interpretace statistických dat

Application of statistical procedures to analyze specific observed or assumed facts from a particular study.
MSH

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alternativní lékařství

diagnostic or therapeutic technique which is presently outside the field of conventional medical practice; for use as a `tag` term index at `T` emphasis level.
CSP

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meruňka

Prunus armeniaca L. is the source of apricots.
MSH

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razoxan

An antimitotic agent with immunosuppressive properties. Dexrazoxane, the (+)-enantiomorph of razoxane, provides cardioprotection against anthracycline toxicity. It appears to inhibit formation of a toxic iron-anthracycline complex.
MSH

A bis-dioxopiperazine and a derivative of the chelating agent EDTA with antineoplastic activity. Razoxane inhibits the enzyme topoisomerase II without inducing DNA strand breaks, thereby inhibiting DNA synthesis and inducing cytotoxicity. Although its mechanism is unknown, this agent exhibits anti-angiogenic activity. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39480&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39480&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C801″ NCI Thesaurus)
PDQ

An orally bioavailable bis-dioxopiperazine and a derivative of the chelating agent ethylenediaminetetraacetic acid (EDTA) with antineoplastic, antiangiogenic, and antimetastatic activities. Razoxane specifically inhibits the enzyme topoisomerase II without inducing DNA strand breaks, which may result in the inhibition of DNA synthesis and cell division in the premitotic and early mitotic phases of the cell cycle. This agent may also exhibit antiangiogenic and antimetastatic activities although the precise molecular mechanisms of these actions are unknown.
NCI

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