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duševně nemocní

Persons with psychiatric illnesses or diseases, particularly psychotic and severe mood disorders.
MSH

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radikální krční disekce

A surgical procedure in which all the ipsilateral cervical lymph node groups of the neck, internal jugular vein, sternocleidomastoid muscle, spinal accessory nerve, and submandibular gland are removed.
NCI

A surgical operation for head and neck malignancies, most of which are squamous cell carcinomas. The neck is opened laterally, the majority of the sternocleidomastoid muscle is removed, as are the regional cervical lymph nodes, the jugular vein, the spinal accessory nerve, the submaxillary gland and most of the parotid gland. There are several modifications. (From Segen, Dictionary of Modern Medicine, 1992, p605)
MSH

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úřední publikace

Works consisting of documents issued by local, regional, or national governments or by their agencies or subdivisions.
MSH

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alkylační látky

Highly reactive chemicals that introduce alkyl radicals into biologically active molecules and thereby prevent their proper functioning. Many are used as antineoplastic agents, but most are very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. They have also been used as components in poison gases.
MSH

chemical agent that can add alkyl groups (for example, ethyl or methyl groups) to another molecule; many mutagens act through alkylation.
CSP

A type of drug that is used in the treatment of cancer. It interferes with the cell`s DNA and inhibits cancer cell growth.
NCI

Agents that replace hydrogen atom(s) in biologically active molecules with alky radical(s), hindering proper function. Alkylating agents exhibit cytotoxic effects through the alkylation of DNA, resulting in strand cross-linking, ultimately inhibiting DNA replication and cell growth.
NCI

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způsobilost zastávat místo na klinice

The capability to perform acceptably those duties directly related to patient care.
MSH

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Mezenterická panikulitida

Inflammation of the ADIPOSE TISSUE in the MESENTERY, a form of peritoneal panniculitis, It is characterized by the presence of MULTINUCLEATED GIANT CELLS and lipid-laden MACROPHAGES in the mesentery.
MSH

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hygiena záření

Health concerns associated with the effects of radiation on the environment and on public and personal health.
MSH

the health effects of radiation; includes effects and hazards from environmental radiation fallout, occupational radiation, diagnostic or therapeutic radiological equipment or materials.
CSP

Studies focusing on the effects of radiation on the environment and on public and personal health.
NCI

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Poaceae

large family of narrow-leaved herbaceous grasses; food grains come from members of this family; hay fever can be induced by pollen of many of the grasses.
CSP

A large family of narrow-leaved herbaceous grasses of the order Cyperales, subclass Commelinidae, class Liliopsida (monocotyledons). Food grains (CEREALS) come from members of this family. RHINITIS, ALLERGIC, SEASONAL can be induced by POLLEN of many of the grasses.
MSH

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Alouatta

A genus of the subfamily ALOUATTINAE, family ATELIDAE, inhabiting the forests of Central and South America. Howlers travel in groups and define their territories by howling accompanied by vigorously shaking and breaking branches.
MSH

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klorazepát dvojdraselný

A water-soluble benzodiazepine derivative effective in the treatment of anxiety. It has also muscle relaxant and anticonvulsant actions.
MSH

A benzodiazepine with anxiolytic, sedative, hypnotic, and anticonvulsant properties. Clorazepate dipotassium exerts its effect by de-activating the nervous system through potentiation of the inhibitory effect of gamma-aminobutyric acid (GABA) on the GABA-A receptors by binding to a site that is distinct from the GABA binding site. Its inhibitory effect is caused by an increase in GABA-mediated chloride channel opening events, leading to hyperpolarization and synaptic inhibition.
NCI

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prvky aktiniové řady

elements of atomic munber 89 and higher; all are radioactive.
CSP

A series of radioactive elements from ACTINIUM, atomic number 89, to and including LAWRENCIUM, atomic number 103.
MSH

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Ranidae

The family of true frogs of the order Anura. The family occurs worldwide except in Antarctica.
MSH

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guajak

Resin from wood of certain species of GUAIACUM. It is used as clinical reagent for occult blood.
MSH

A substance from a type of tree called Guaiacum that grows in the Caribbean. Guaiac is used in the fecal occult blood test (a test for blood in human stool samples).
NCI

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alternativní lékařství

diagnostic or therapeutic technique which is presently outside the field of conventional medical practice; for use as a `tag` term index at `T` emphasis level.
CSP

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Coccidia

A subclass of protozoans commonly parasitic in the epithelial cells of the intestinal tract but also found in the liver and other organs. Its organisms are found in both vertebrates and higher invertebrates and comprise two orders: EIMERIIDA and EUCOCCIDIIDA.
MSH

subclass of protozoans commonly parasitic in epithelial cells of the intestinal tract but also found in the liver and other organs; organisms are found in both vertebrates and higher invertebrates and comprise three orders: Eimeriida, Eucoccidiida and Lankesterellidae.
CSP

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methachalon

A quinazoline derivative with hypnotic and sedative properties. It has been withdrawn from the market in many countries because of problems with abuse. (From Martindale, The Extra Pharmacopoeia, 30th ed, p604)
MSH

A sedative, hypnotic agent that was used for insomnia, but was taken off of the market, in the U.S., in 1983 due to its high risk of abuse.(NCI)
NCI

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razoxan

An antimitotic agent with immunosuppressive properties. Dexrazoxane, the (+)-enantiomorph of razoxane, provides cardioprotection against anthracycline toxicity. It appears to inhibit formation of a toxic iron-anthracycline complex.
MSH

A bis-dioxopiperazine and a derivative of the chelating agent EDTA with antineoplastic activity. Razoxane inhibits the enzyme topoisomerase II without inducing DNA strand breaks, thereby inhibiting DNA synthesis and inducing cytotoxicity. Although its mechanism is unknown, this agent exhibits anti-angiogenic activity. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39480&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39480&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C801″ NCI Thesaurus)
PDQ

An orally bioavailable bis-dioxopiperazine and a derivative of the chelating agent ethylenediaminetetraacetic acid (EDTA) with antineoplastic, antiangiogenic, and antimetastatic activities. Razoxane specifically inhibits the enzyme topoisomerase II without inducing DNA strand breaks, which may result in the inhibition of DNA synthesis and cell division in the premitotic and early mitotic phases of the cell cycle. This agent may also exhibit antiangiogenic and antimetastatic activities although the precise molecular mechanisms of these actions are unknown.
NCI

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guma arabská

Powdered exudate from various Acacia species, especially A. senegal (Leguminosae). It forms mucilage or syrup in water. Gum arabic is used as a suspending agent, excipient, and emulsifier in foods and pharmaceuticals.
MSH

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Ambystomatidae

A family of the class Urodela which includes 4 living genera, about 33 species, and occurs only in North America. Adults are usually terrestrial, but the larval forms are aquatic.
MSH

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káva

A beverage made from ground COFFEA beans (SEEDS) infused in hot water. It generally contains CAFFEINE and THEOPHYLLINE unless it is decaffeinated.
MSH

widely consumed beverage made from roasted and ground seeds of Coffea plants infused in hot water; generally contains caffeine and theophylline unless it is decaffeinated.
CSP

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methyklothiazid

A thiazide diuretic with properties similar to those of HYDROCHLOROTHIAZIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p825)
MSH

A thiazide diuretic with antihypertensive activity. Methyclothiazide directly inhibits sodium and chloride reabsorption on the luminal membrane of the early segment of the distal convoluted tubule in the kidney. This results in an increase in water, sodium, chloride, potassium and bicarbonate excretion and a decrease in calcium and uric acid secretion.
NCI

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receptor epidermálního růstového faktoru

A cell surface receptor involved in regulation of cell growth and differentiation. It is specific for EPIDERMAL GROWTH FACTOR and EGF related peptides including TRANSFORMING GROWTH FACTOR ALPHA, amphiregulin, and heparin-binding EGF-like growth factor. The binding of ligand to the receptor causes activation of its intrinsic tyrosine kinase activity and rapid internalization of the receptor-ligand complex into the cell.
MSH

Epidermal growth factor receptor (1210 aa, 134 kD) is a cell adhesion process protein that is encoded by the human EGFR gene and has roles in cell-cell adhesion, cell migration, cell proliferation and signal transduction.
NCI

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vlasy – nemoci

Diseases affecting the orderly growth and persistence of hair.
MSH

Did you know that the average person has 5 million hairs? Hair grows all over your body except on your lips, palms and the soles of your feet. It takes about a month for healthy hair to grow half an inch. Most hairs grow for up to six years and then fall out. New hairs grow in their place.

Hair helps keep you warm. It also protects your eyes, ears and nose from small particles in the air. Common problem with the hair and scalp include hair loss, infections, and flaking.


MEDLINEPLUS

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Activation of Amino Acids

The modification of an amino acid to an active form, for incorporation into a peptide, protein or other macromolecule. [GOC:jl]
GO

A reaction that produces an “activated” amino acid derivative, such as amino acyl adenylate, or amino acylphosphorylate and provides energy for the amino acid to be incorporated into a peptide, protein, or other macromolecule.
MSH

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kolagen typ II

A fibrillar collagen found predominantly in CARTILAGE and vitreous humor. It consists of three identical alpha1(II) chains.
MSH

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methylfenazoniummethosulfát

Used as an electron carrier in place of the flavine enzyme of Warburg in the hexosemonophosphate system and also in the preparation of SUCCINIC DEHYDROGENASE.
MSH

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receptory steroidů

Proteins found usually in the cytoplasm or nucleus that specifically bind steroid hormones and trigger changes influencing the behavior of cells. The steroid receptor-steroid hormone complex regulates the transcription of specific genes.
MSH

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handling (psychologie)

Physical manipulation of animals and humans to induce a behavioral or other psychological reaction. In experimental psychology, the animal is handled to induce a stress situation or to study the effects of “gentling” or “mothering”.
MSH

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5-aminolevulátsynthetasa

An enzyme of the transferase class that catalyzes condensation of the succinyl group from succinyl coenzyme A with glycine to form delta-aminolevulinate. It is a pyridoxyal phosphate protein and the reaction occurs in mitochondria as the first step of the heme biosynthetic pathway. The enzyme is a key regulatory enzyme in heme biosynthesis. In liver feedback is inhibited by heme. EC 2.3.1.37.
MSH

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barva

The visually perceived property of objects created by absorption or reflection of specific wavelengths of light.
MSH

The appearance of objects (or light sources) described in terms of a person`s perception of their hue and lightness (or brightness) and saturation.
NCI

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