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mannitoldehydrogenasy

Sugar alcohol dehydrogenases that have specificity for MANNITOL. Enzymes in this category are generally classified according to their preference for a specific reducing cofactor.
MSH

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mannitolfosfáty

Phosphoric acid esters of mannitol.
MSH

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mannoheptulosa

A 7-carbon keto sugar having the mannose configuration.
MSH

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mannomustin

Nitrogen mustard derivative alkylating agent used as antineoplastic. It causes severe bone marrow depression and is a powerful vesicant.
MSH

A nitrogen mustard derivative that cross-links with DNA, causing inhibition of DNA synthesis. It may be used to treat certain cancers, but may cause a higher incidence of leukemia and a dose-related incidence of lung tumors in animals. (NCI)
NCI

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mannosa

A hexose or fermentable monosaccharide and isomer of glucose from manna, the ash Fraxinus ornus and related plants. (From Grant & Hackh`s Chemical Dictionary, 5th ed & Random House Unabridged Dictionary, 2d ed)
MSH

hexose or fermentable monosaccharide and isomer of glucose; occurs in oligosaccharides of many glycoproteins and glycolipids.
CSP

A hexose which is an epimer at C-2 of glucose. Structurally, it is similar to glucose with the OH and H groups interchanged at carbon-2.
NCI

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mannosa-6-fosfátisomerasa

An enzyme that catalyzes the reversible isomerization of D-mannose-6-phosphate to form D-fructose-6-phosphate, an important step in glycolysis. EC 5.3.1.8.
MSH

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mannosafosfáty

Phosphoric acid esters of mannose.
MSH

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mannosidasy

Glycoside hydrolases that catalyze the hydrolysis of alpha or beta linked MANNOSE.
MSH

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mannosidy

Glycosides formed by the reaction of the hydroxyl group on the anomeric carbon atom of mannose with an alcohol to form an acetal. They include both alpha- and beta-mannosides.
MSH

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alfa-mannosidóza

An autosomal recessive lysosomal storage disease characterized by deficient activity of the enzyme alpha-D-mannosidase. There is a wide range of signs and symptoms including hepatomegaly, splenomegaly, hearing loss, respiratory infections, mental retardation, skeletal abnormalities, leveled nasal bridge and protruding forehead.
NCI

An inborn error of metabolism marked by a defect in the lysosomal isoform of ALPHA-MANNOSIDASE activity that results in lysosomal accumulation of mannose-rich intermediate metabolites. Virtually all patients have psychomotor retardation, facial coarsening, and some degree of dysostosis multiplex. It is thought to be an autosomal recessive disorder.
MSH

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mannosyltransferasy

Enzymes that catalyze the transfer of mannose from a nucleoside diphosphate mannose to an acceptor molecule which is frequently another carbohydrate. The group includes EC 2.4.1.32, EC 2.4.1.48, EC 2.4.1.54, and EC 2.4.1.57.
MSH

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manometrie

Measurement of the pressure or tension of liquids or gases with a manometer.
MSH

Measurement of the pressure or tension of liquids or gases.
NCI

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manpower

Used with disciplines and programs for the demand, supply, distribution, recruitment, and use of personnel.
MSH

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Mansonella

A genus of parasitic nematodes whose organisms are distributed in Central and South America. Characteristics include a smooth cuticle and an enlarged anterior end.
MSH

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mansoneliáza

Infection with nematodes of the genus MANSONELLA. Symptoms include pruritus, headache, and articular swelling.
MSH

A parasitic infection caused by the nematode Mansonella. Signs and symptoms include pruritus, headache, fever, arthralgias, and eosinophilia.
NCI

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Mantodea

An order of insects, comprising a single family (Mantidae), restricted almost entirely to the tropics. Only one species, the praying mantis (Mantis religiosa), is found in temperate habitats.
MSH

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posunková komunikace

Method of nonverbal communication utilizing hand movements as speech equivalents.
MSH

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manuály jako téma

A small handbook.
NCI

Books designed to give factual information or instructions.
MSH

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hnůj

Accumulations of solid or liquid animal excreta usually from stables and barnyards with or without litter material. Its chief application is as a fertilizer. (From Webster`s 3d ed)
MSH

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nemoc s močí javorového sirupu

An autosomal recessive inherited disorder with multiple forms of phenotypic expression, caused by a defect in the oxidative decarboxylation of branched-chain amino acids (AMINO ACIDS, BRANCHED-CHAIN). These metabolites accumulate in body fluids and render a “maple syrup” odor. The disease is divided into classic, intermediate, intermittent, and thiamine responsive subtypes. The classic form presents in the first week of life with ketoacidosis, hypoglycemia, emesis, neonatal seizures, and hypertonia. The intermediate and intermittent forms present in childhood or later with acute episodes of ataxia and vomiting. (From Adams et al., Principles of Neurology, 6th ed, p936)
MSH

An autosomal recessive inherited disorder caused by mutations in the BCKDHA, BCKDHB, DBT, and DLD genes. It is characterized by a deficiency of branched-chain alpha-keto acid dehydrogenase complex, leading to accumulation of metabolites in the body fluids. The name of the disease derives from the sweet odor of the urine in infants, reminiscent of maple syrup. Signs and symptoms usually appear in infancy and include lethargy and developmental delays. If untreated, it may lead to seizures, coma, and death.
NCI

autosomal recessive inherited disorder with multiple forms of phenotypic expression, caused by a defect in the oxidative decarboxylation of branched-chain amino acids; metabolites accumulate in body fluids and render a “maple syrup” odor; divided into classic, intermediate, intermittent, and thiamine responsive subtypes; classic form presents in the first week of life with ketoacidosis, hypoglycemia, emesis, neonatal seizures, and hypertonia; the intermediate and intermittent forms present in childhood or later with acute episodes of ataxia and vomiting.
CSP

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maprotilin

A bridged-ring tetracyclic antidepressant that is both mechanistically and functionally similar to the tricyclic antidepressants, including side effects associated with its use.
MSH

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mapy

A usually 2-dimensional diagrammatic representation of an object or area.
NCI

Works consisting of representations, normally to scale and on a flat medium, of a selection of material or abstract features on the surface of the earth. They may be used also in delineating the heavens and celestial bodies. (From Anglo-American Cataloguing Rules, 2d ed, p619)
MSH

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Lake Victoria marburgvirus

genus in family Filoviridae.
CSP

The type species of MARBURGVIRUS, associated with severe illness in workers handling tissues of African green monkeys.
MSH

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marburgská virová nemoc

An RNA virus infection of rhesus, vervet, and squirrel monkeys transmissible to man.
MSH

A viral infectious disorder caused by Marburg virus. Signs and symptoms include fever, headache, myalgias, chest and abdominal pain, jaundice, liver failure, massive hemorrhaging, and multiple organ failure.
NCI

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Paroxysmální noční hemoglobinurie

disorder characterized by intravascular hemolysis and hemoglobinuria; some cases occur on exposure to cold and are due to the presence of an autohemolysin in the serum; other cases are more marked during or immediately after sleep and are considered to be due to an acquired intracorpuscular defect.
CSP

A rare acquired hematologic disorder characterized by hemolytic anemia, dark-colored urine due to the release of hemoglobin in the blood, and thrombosis. The episodes of hemolysis tend to occur at night. It is caused by a somatic mutation in the glycosylphosphatidylinositol biosynthesis gene.
NCI

A rare disorder in which red blood cells are easily destroyed by certain immune system proteins. Symptoms include blood clots, and red or brownish urine in the morning. Aplastic anemia (decreased production of blood cells) may lead to PNH, and people with PNH are at increased risk of acute myelogenous leukemia.
NCI

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Markova nemoc

A transmissible viral disease of birds caused by avian herpesvirus 2 (HERPESVIRUS 2, GALLID) and other MARDIVIRUS. There is lymphoid cell infiltration or lymphomatous tumor formation in the peripheral nerves and gonads, but may also involve visceral organs, skin, muscle, and the eye.
MSH

highly contagious virus disease of poultry that is characterized especially by proliferation of lymphoid cells and is caused by a herpesvirus having several serotypes.
CSP

A viral infection in chickens caused by the herpes virus. It is characterized by tissue lymphocytic infiltration, limb paralysis and development of tumors.
NCI

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virus Markovy nemoci

The type species of the genus MARDIVIRUS in the family HERPESVIRIDAE. It is the etiologic agent of MAREK DISEASE, infecting domestic fowl and wild birds.
MSH

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Marfanův syndrom

An autosomal dominant disorder of CONNECTIVE TISSUE with abnormal features in the heart, the eye, and the skeleton. Cardiovascular manifestations include MITRAL VALVE PROLAPSE, dilation of the AORTA, and aortic dissection. Other features include lens displacement (ectopia lentis), disproportioned long limbs and enlarged DURA MATER (dural ectasia). Marfan syndrome is associated with mutations in the gene encoding fibrillin, a major element of extracellular microfibrils of connective tissue.
MSH

disorder of connective tissue characterized by tall stature, elongated extremities, subluxation of the lens, dilatation of the ascending aorta, and “pigeon breast”; inherited as an autosomal dominant trait.
CSP

A genetic syndrome inherited as an autosomal dominant trait. It is caused by mutations in the FBN1 gene. It is characterized by tall stature, elongated extremities, mitral valve prolapse, aortic dilatation, aortic dissection, and sublaxation of the lens.
NCI

Marfan syndrome is a disorder that affects connective tissue. Connective tissues are proteins that support skin, bones, blood vessels and other organs. One of these proteins is fibrillin. A problem with the fibrillin gene causes Marfan syndrome.

Marfan syndrome can be mild to severe, and the symptoms can vary. People with Marfan syndrome are often very tall, thin and loose jointed. Most people with Marfan syndrome have heart and blood vessel problems, such as a weakness in the aorta or heart valves that leak. They may also have problems with their bones, eyes, skin, nervous system and lungs.

NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases


MEDLINEPLUS

A hereditary disorder of connective tissue characterized by tall stature, elongated extremities, dilatation of the ascending aorta, and pigeon breast.
CHV

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margarín

A butterlike product made of refined vegetable oils, sometimes blended with animal fats, and emulsified usually with water or milk. It is used as a butter substitute. (From Random House Unabridged Dictionary, 2d ed)
MSH

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marginální vřed

An ulcer that develops in the jejunal mucosa close to the anastomosis site following a gastroenterostomy procedure.
NCI

A disorder characterized by a circumscribed, inflammatory and necrotic erosive lesion on the jejunal mucosal surface close to the anastomosis site following a gastroenterostomy procedure.
NCI

A well-known complication of GASTROENTEROSTOMY. These ulcers occur at the gastrojejunal anastomosis, mostly on the jejunal side.
MSH

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