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metriální žláza

Collection of granular epithelial cells in the uterine muscle beneath the placenta that develop during pregnancy in certain species of animals.
MSH

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metribolon

A synthetic non-aromatizable androgen and anabolic steroid. It binds strongly to the androgen receptor and has therefore also been used as an affinity label for this receptor in the prostate and in prostatic tumors.
MSH

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metrická soustava

A system of units used in scientific work throughout the world and employed in general commercial transactions and engineering applications. Its units of length, time, and mass are the meter, second, and kilogram respectively, or decimal multiples and submultiples thereof. ( McGraw-Hill Dictionary of Scientific and Technical Terms, 6th ed)
MSH

An international decimal system of weights and measures, in which the basic units are the meter for length, the gram for weight, and the liter for volume. The metric system units have to satisfy three conditions: one fundamental unit is defined for each quantity; multiples and fractions of fundamental units are created by adding prefixes (denoting powers of ten) to the names of the defined units; the fundamental units are defined rationally and are related to each other in a rational fashion. The metric system evolved into the International System of Units (Systeme International d`Unites, SI).
NCI

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metrizamid

A solute for density gradient centrifugation offering higher maximum solution density without the problems of increased viscosity. It is also used as a resorbable, non-ionic contrast medium.
MSH

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metrizoát

A diagnostic radiopaque that usually occurs as the sodium salt.
MSH

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metronidazol

A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS. It has also been proposed as a radiation sensitizer for hypoxic cells. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985, p133), this substance may reasonably be anticipated to be a carcinogen (Merck, 11th ed).
MSH

antiprotozoal and antibacterial effective against obligate anaerobes.
CSP

A drug that is used to treat infection and is being studied in the treatment of cancer. It is a type of antibacterial, antiprotozoal, and anthelmintic.
NCI

a drug that treats bacterial and fungal infection
CHV

A synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities. Although its mechanism of action is not fully elucidated, un-ionized metronidazole is readily taken up by obligate anaerobic organisms and is subsequently reduced by low-redox potential electron-transport proteins to an active, intermediate product. Reduced metronidazole causes DNA strand breaks, thereby inhibiting DNA synthesis and bacterial cell growth. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39503&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39503&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C651″ NCI Thesaurus)
PDQ

A synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities. Although its mechanism of action is not fully elucidated, un-ionized metronidazole is readily taken up by obligate anaerobic organisms and is subsequently reduced by low-redox potential electron-transport proteins to an active, intermediate product. Reduced metronidazole causes DNA strand breaks, thereby inhibiting DNA synthesis and bacterial cell growth.
NCI

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HILEROKOARTEKO ODOLJARIOA ETA ZIKLOKO BESTE ZENBAIT NAHASTE

Abnormal uterine bleeding that is not related to MENSTRUATION, usually in females without regular MENSTRUAL CYCLE. The irregular and unpredictable bleeding usually comes from a dysfunctional ENDOMETRIUM.
MSH

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metyrapon

An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
MSH

USP lists as a diagnostc aid for determination of pituitary function.
CSP

A pyridine derivative and a glucocorticoid synthesis inhibitor. Metyrapone inhibits 11-beta-hydroxylase, thereby inhibiting synthesis of cortisol from 11-deoxycortisol and corticosterone from desoxycorticosterone in the adrenal gland. Removal of the negative feedback mechanism exerted by cortisol results in increased adrenocorticotropic hormone (ACTH) secretion by the pituitary gland. In turn, continuing stimulation of adrenal gland by ACTH results in accumulation of corticoid precursors, 11-desoxycortisol and desoxycorticosterone. These metabolites are excreted in urine that maybe used as indicators for pituitary responsiveness.
NCI

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mevinfos

An organophosphate cholinesterase inhibitor that is used as an insecticide.
MSH

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Američané mexického původu

use this term to index residents of the U.S. or other American country, including Mexico, who are of Mexican origin or ancestry (typo in SN MBL).
CSP

Persons living in the United States of Mexican descent.
MSH

Denotes an american citizen of Mexican decent.
NCI

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Mexiko

North American country south of the United States of America.
CSP

A country in Central America, bordering the Caribbean Sea and the Gulf of Mexico, between Belize and the US and bordering the North Pacific Ocean, between Guatemala and the US. (NCI)
NCI

Description:Realm code for use of Mexico


HL7V3.0

A country in Central America, bordering the Caribbean Sea and the Gulf of Mexico, between Belize and the US and bordering the North Pacific Ocean, between Guatemala and the US. (CIA World Factbook 2002)
NCI

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mexiletin

Antiarrhythmic agent pharmacologically similar to LIDOCAINE. It may have some anticonvulsant properties.
MSH

antiarrhythmia agent pharmacologically similar to lidocaine.
CSP

A local anesthetic and antiarrhythmic (Class IB) agent structurally related to lidocaine. Mexiletine exerts its antiarrhythmic effect by inhibiting the inward sodium current in cardiac cells, thereby reducing the rate of rise of the cardiac action potential (phase 0) and decreases automaticity in the Purkinje fibers. This slows nerve impulses in the heart and stabilizes the heartbeat. Mexiletine`s anesthetic activity is due to its ability to block sodium influx in peripheral nerves, thereby reducing the rate and intensity of pain impulses reaching the central nervous system.
NCI

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mezlocilin

Semisynthetic ampicillin-derived acylureido penicillin. It has been proposed for infections with certain anaerobes and may be useful in inner ear, bile, and CNS infections.
MSH

A broad-spectrum, beta-lactam penicillin antibiotic with antibacterial activity. Mezlocillin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts the final stage of bacterial cell wall synthesis and results in the weakening of the bacterial cell wall and eventually causing cell lysis.
NCI

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mianserin

A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
MSH

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Mus musculus

the scientific name of the common house mouse; for inbred and mutant strain mice used in research, use LABORATORY MOUSE or narrower terms.
CSP

The common house mouse, often used as an experimental organism.
NCI

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myši inbrední BALB C

Derived from albino mice stocks originally disseminated by Bagg (1913) to Snell in 1932 that has an albino coat with genotype A,b,c. The BALB/c mouse develops plasmacytomas upon injection with mineral oil, which form the mouse cell component of the mouse-human hybrid cells that are used in the production of monoclonal antibodies. This strain exhibits excellent breeding performance and a long life span which contribute to its being one of the most highly utilized of all available mouse strains.
NCI

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myši bezsrsté

homozygous, permanently near-hairless mice which lose their hair at about 10 days of age.
CSP

Mutant strains of mice that produce little or no hair.
MSH

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myši – inbrední kmeny

Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations, or by parent x offspring matings carried out with certain restrictions. All animals within an inbred strain trace back to a common ancestor in the twentieth generation.
MSH

Any strain of mouse that is the product of a mating between close relatives. In biological research, inbreeding allows for the selection of specific genotypes or phenotypes that are of particular importance to the study being carried out.
NCI

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myši Jimpy

Myelin-deficient mutants which are from the inbred Tabby-Jimpy strain.
MSH

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myši laboratorní

mouse that has been bred or acquired for the purpose of being a research subject in a facility where scientific research and experiments are conducted.
CSP

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myši – mutantní kmeny

Mice bearing mutant genes which are phenotypically expressed in the animals.
MSH

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myši – mutanty neurologické

Mice which carry mutant genes for neurologic defects or abnormalities.
MSH

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myši nahé

Mutant mice homozygous for the recessive gene “nude” which fail to develop a thymus. They are useful in tumor studies and studies on immune responses.
MSH

mutant mouse homozygous for the recessive gene, nude, which fail to develop a thymus.
CSP

A type of laboratory mouse that is hairless, lacks a normal thymus gland, and has a defective immune system because of a genetic mutation. Athymic, nude mice are often used in cancer research because they do not reject tumor cells, from mice or other species.
NCI

A hairless mutant mouse with thymic hypoplasia, lacking T-cells. They are unable to reject transplants.
NCI

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myši obézní

Mutant mice exhibiting a marked obesity coupled with overeating, hyperglycemia, hyperinsulinemia, marked insulin resistance, and infertility when in a homozygous state. They may be inbred or hybrid.
MSH

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myši quaking

Mice homozygous for the mutant autosomal recessive gene, quaking (qk), associated with disorder in myelin formation and manifested by axial tremors.
MSH

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myši transgenní

Laboratory mice that have been produced from a genetically manipulated EGG or EMBRYO, MAMMALIAN.
MSH

A mouse whose genome has been altered by the inclusion of foreign genetic material. The technique involves microinjection of foreign DNA fragments into the nucleus of a fertilized egg. The inserted gene becomes integrated into every cell and tissue of the mouse.
NCI

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micely

Particles consisting of aggregates of molecules held loosely together by secondary bonds. The surface of micelles are usually comprised of amphiphatic compounds that are oriented in a way that minimizes the energy of interaction between the micelle and its environment. Liquids that contain large numbers of suspended micelles are referred to as EMULSIONS.
MSH

aggregate of lipids in which the polar head groups face outward and the hydrophobic tails face inward.
CSP

A tiny particle made of substances that are soluble in water and that come together to form a ball-like shape. These particles can carry other substances inside them. In medicine, micelles are made in the laboratory and are used to carry drugs to body tissues and cells.
NCI

A multimolecular colloid particle, usually formed by amphipathic molecules in solution with the polar group toward the solution and the hydrophobic group toward the interior.
NCI

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Michigan

A state in the north central United States. Its capital is Lansing.
NCI

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mikonazol

An imidazole antifungal agent that is used topically and by intravenous infusion.
MSH

An antifungal synthetic derivative of imidazole and used in the treatment of candidal skin infections, Miconazole selectively affects the integrity of fungal cell membranes, high in ergosterol content and different in composition from mammalian cells membranes. (NCI04)
NCI

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mikrobiální testy citlivosti

Any tests that demonstrate the relative efficacy of different chemotherapeutic agents against specific microorganisms (i.e., bacteria, fungi, viruses).
MSH

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