Additional pages

myosarkom

A general term for a malignant neoplasm derived from muscular tissue. (Stedman, 25th ed)
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myosiny

superfamily of proteins that function as translocating proteins the common characteristics are to bind actin and hydrolyze MgATP generally consist of heavy chains which are involved in locomotion, and light chains which are are involved in regulation superfamily of myosins is organized into structural classes based upon the type and arrangement of the subunits they contain.
CSP

A diverse superfamily of proteins that function as translocating proteins. They share the common characteristics of being able to bind ACTINS and hydrolyze MgATP. Myosins generally consist of heavy chains which are involved in locomotion, and light chains which are involved in regulation. Within the structure of myosin heavy chain are three domains: the head, the neck and the tail. The head region of the heavy chain contains the actin binding domain and MgATPase domain which provides energy for locomotion. The neck region is involved in binding the light-chains. The tail region provides the anchoring point that maintains the position of the heavy chain. The superfamily of myosins is organized into structural classes based upon the type and arrangement of the subunits they contain.
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nesvalový myosin typ IIB

A nonmuscle isoform of myosin type II found predominantly in neuronal tissue.
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myosin – těžké řetězce

The larger subunits of MYOSINS. The heavy chains have a molecular weight of about 230 kDa and each heavy chain is usually associated with a dissimilar pair of MYOSIN LIGHT CHAINS.
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myosin typ II

The subfamily of myosin proteins that are commonly found in muscle fibers. Myosin II is also involved a diverse array of cellular functions including cell division, transport within the GOLGI APPARATUS, and maintaining MICROVILLI structure.
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myosin – lehké řetězce

The smaller subunits of MYOSINS that bind near the head groups of MYOSIN HEAVY CHAINS. The myosin light chains have a molecular weight of about 20 KDa and there are usually one essential and one regulatory pair of light chains associated with each heavy chain. Many myosin light chains that bind calcium are considered “calmodulin-like” proteins.
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myosinové subfragmenty

Parts of the myosin molecule resulting from cleavage by proteolytic enzymes (PAPAIN; TRYPSIN; or CHYMOTRYPSIN) at well-localized regions. Study of these isolated fragments helps to delineate the functional roles of different parts of myosin. Two of the most common subfragments are myosin S-1 and myosin S-2. S-1 contains the heads of the heavy chains plus the light chains and S-2 contains part of the double-stranded, alpha-helical, heavy chain tail (myosin rod).
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Ventricular alpha-Myosin

A form of ventricular myosin that contains two alpha-myosin heavy chains. It has a higher ATPase activity and contracts at a faster rate than myosins containing beta-myosin heavy chains.
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Ventricular beta-Myosin

A form of ventricular myosin that contains two beta-myosin heavy chains. It has a lower ATPase activity and contracts at a slower rate than myosins containing alpha-myosin heavy chains.
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kinasa lehkého řetězce myosinu

An enzyme that phosphorylates myosin light chains in the presence of ATP to yield myosin-light chain phosphate and ADP, and requires calcium and CALMODULIN. The 20-kDa light chain is phosphorylated more rapidly than any other acceptor, but light chains from other myosins and myosin itself can act as acceptors. The enzyme plays a central role in the regulation of smooth muscle contraction.
MSH

mediates calcium-calmodulin dependent phosphorylation of myosin light chain (20 kD) subunits to initiate smooth muscle and other actomyosin based cellular contractility systems inactivated by cyclic AMP dependent protein kinase, accounting for relaxant effect of cAMP.
CSP

Myosin Light Polypeptide Kinase, encoded by the MYLK gene, is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3` region, it encodes telokin, a small protein identical in sequence to the C terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the other arm of chromosome 3. Seven transcript variants that produce seven isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. (from LocusLink)
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myozitida

Inflammation of a muscle or muscle tissue.
MSH

inflammation of skeletal muscle.
CSP

Myositis is inflammation of your skeletal muscles, which are also called the voluntary muscles. These are the muscles you consciously control that help you move your body. An injury, infection or autoimmune disease can cause myositis.

The diseases dermatomyositis and polymyositis both involve myositis. Polymyositis causes muscle weakness, usually in the muscles closest to the trunk of your body. Dermatomyositis causes muscle weakness, plus a skin rash. Both diseases are usually treated with prednisone, a steroid medicine, and sometimes other medicines.


MEDLINEPLUS

A disorder characterized by inflammation involving the skeletal muscles.
NCI

An inflammatory process affecting the skeletal muscles. Causes include infections, injuries, and autoimmune disorders.
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myositis ossificans

A disease characterized by bony deposits or the ossification of muscle tissue.
MSH

A disorder characterized by non-neoplastic bone formation in soft tissues. It usually follows blunt trauma and bleeding in the deep soft tissues.
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myotonie

Prolonged failure of muscle relaxation after contraction. This may occur after voluntary contractions, muscle percussion, or electrical stimulation of the muscle. Myotonia is a characteristic feature of MYOTONIC DISORDERS.
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myotonická dystrofie

An autosomal dominant neuromuscular disorder which usually presents in early adulthood, characterized by progressive muscular atrophy (most frequently involving the hands, forearms, and face), myotonia, frontal baldness, lenticular opacities, and testicular atrophy. Cardiac conduction abnormalities, diaphragmatic weakness, and mild INTELLECTUAL DISABILITY may also occur. Congenital myotonic dystrophy is a severe form of this disorder, characterized by neonatal MUSCLE HYPOTONIA, feeding difficulties, respiratory muscle weakness, and an increased incidence of INTELLECTUAL DISABILITY. (From Adams et al., Principles of Neurology, 6th ed, pp1423-5; Joynt, Clinical Neurology, 1997, Ch16, pp16-7)
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autosomal dominant neuromuscular disorder which usually presents in early adulthood, characterized by progressive muscular atrophy (most frequently involving the hands, forearms, and face), myotonia, frontal baldness, lenticular opacities, and testicular atrophy; cardiac conduction abnormalities, diaphragmatic weakness, and mild mental retardation may also occur; congenital myotonic dystrophy is a severe form of this disorder.
CSP

An inherited progressive disorder affecting the muscles. It is characterized by muscle wasting and hypotonia, cataracts, heart conduction defects and endocrinopathies.
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myotonia congenita

Inherited myotonic disorders with early childhood onset MYOTONIA. Muscular hypertrophy is common and myotonia may impair ambulation and other movements. It is classified as Thomsen (autosomal dominant) or Becker (autosomal recessive) generalized myotonia mainly based on the inheritance pattern. Becker type is also clinically more severe. An autosomal dominant variant with milder symptoms and later onset is known as myotonia levior. Mutations in the voltage-dependent skeletal muscle chloride channel are associated with the disorders.
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A genetic congenital neuromuscular disorder affecting the skeletal muscles. It is caused by mutations in the chloride channel gene (CLCN1 gene). It is characterized by muscle stiffness, hypertrophy, pain, and cramping.
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Myoxidae

A family of nocturnal rodents, similar in appearance to SQUIRRELS, but smaller. There are 28 species, half of which are found in Africa.
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myringoplastika

Surgical restoration of a perforated tympanic membrane by grafting. (Dorland, 28th ed.)
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myristany

Salts and esters of the 14-carbon saturated monocarboxylic acid–myristic acid.
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kyselina myristová

A saturated 14-carbon fatty acid occurring in most animal and vegetable fats, particularly butterfat and coconut, palm, and nutmeg oils. It is used to synthesize flavor and as an ingredient in soaps and cosmetics. (From Dorland, 28th ed)
MSH

A saturated long-chain fatty acid with a 14-carbon backbone. Myristic acid is found naturally in palm oil, coconut oil and butter fat.
NCI

Saturated fatty acid with 14 carbons.
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kyseliny myristové

14-carbon saturated monocarboxylic acids.
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mysticismus

A philosophy based upon spiritual intuition that is believed to transcend ordinary sensory experiences or understanding.
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mytologie

A body of stories, the origins of which may be unknown or forgotten, that serve to explain practices, beliefs, institutions or natural phenomena. Mythology includes legends and folk tales. It may refer to classical mythology or to a body of modern thought and modern life. (From Webster`s 1st ed)
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Mytilus

A genus of marine mussels in the family MYTILIDAE, class BIVALVIA. The species MYTILUS EDULIS is the highly edible common mussel.
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HIPOTIROIDISMOA/MISOEDEMA

A condition characterized by a dry, waxy type of swelling (EDEMA) with abnormal deposits of MUCOPOLYSACCHARIDES in the SKIN and other tissues. It is caused by a deficiency of THYROID HORMONES. The skin becomes puffy around the eyes and on the cheeks. The face is dull and expressionless with thickened nose and lips.
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condition characterized by a dry, waxy type of swelling with abnormal deposits of mucin in the skin and other tissues; it is produced by a functional insufficiency of the thyroid gland, resulting in deficiency of thyroid hormone.
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Myxobacterales

order of rod shaped, gram negative fruiting gliding bacteria found in soil, water and humus.
CSP

An order of rod-shaped, gram-negative fruiting gliding bacteria found in SOIL; WATER; and HUMUS.
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myxom

A benign neoplasm derived from connective tissue, consisting chiefly of polyhedral and stellate cells that are loosely embedded in a soft mucoid matrix, thereby resembling primitive mesenchymal tissue. It occurs frequently intramuscularly where it may be mistaken for a sarcoma. It appears also in the jaws and the skin. (From Stedman, 25th ed)
MSH

A benign soft tissue neoplasm characterized by the presence of spindle and stellate cells, lobulated growth pattern, and myxoid stroma formation.
NCI

A benign soft tissue neoplasm characterized by the presence of neoplastic spindle and stellate cells in a myxoid stroma.
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virus myxomatózy

The type species of LEPORIPOXVIRUS causing infectious myxomatosis, a severe generalized disease, in rabbits. Tumors are not always present.
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Myxomycetes

A division of organisms that exist vegetatively as complex mobile plasmodia, reproduce by means of spores, and have complex life cycles. They are now classed as protozoa but formerly were considered fungi.
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phylum consisting of organisms that exist vegetatively as complex mobile plasmodia, reproduce by means of spores, and have complex life cycles; now classed as protozoa but formerly considered fungi.
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myxosarkom

A sarcoma, usually a liposarcoma or malignant fibrous histiocytoma, with an abundant component of myxoid tissue resembling primitive mesenchyme containing connective tissue mucin. (Stedman, 25th ed)
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An infiltrating malignant soft tissue neoplasm characterized by the presence of immature undifferentiated cells and abundant myxoid stroma formation.
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N,N-dimethyltryptamin

An N-methylated indoleamine derivative, a serotonergic hallucinogen found in several plants, especially Prestonia amazonica (Apocynaceae) and in mammalian brain, blood, and urine. It apparently acts as an agonist at some types of serotonin receptors and an antagonist at others.
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a kind of hallucinogenic drug
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