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nehty

The thin, horny plates that cover the dorsal surfaces of the distal phalanges of the fingers and toes of primates.
MSH

The cutaneous plate on the dorsal surface of the distal end of a finger or toe. (NCI)
NCI

The cutaneous plate on the dorsal surface of the distal end of a finger or toe.
NCI

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nehty zarostlé

Excessive lateral nail growth into the nail fold. Because the lateral margin of the nail acts as a foreign body, inflammation and granulation may result. It is caused by improperly fitting shoes and by improper trimming of the nail.
MSH

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nehty malformované

Deformities in nail structure or appearance, including hypertrophy, splitting, clubbing, furrowing, etc. Genetic diseases such as PACHYONYCHIA CONGENITA can result in malformed nails.
MSH

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nairobská nemoc ovcí

An arbovirus infection of sheep and goats transmitted by ticks. It is characterized by high fever and hemorrhagic gastroenteritis.
MSH

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virus nairobské nemoci ovcí

A species of NAIROVIRUS, transmitted by the ixodid ticks and producing a lethal gastroenteritis in sheep and goats. Though a major veterinary pathogen, its effect on humans has not been firmly established.
MSH

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nalbufin

A narcotic used as a pain medication. It appears to be an agonist at kappa opioid receptors and an antagonist or partial agonist at mu opioid receptors.
MSH

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naled

An organophosphate cholinesterase inhibitor that is used as an insecticide and as an acaricide.
MSH

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kyselina nalidixová

A synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA GYRASE.
MSH

A synthetic quinolone and antibacterial agent with urinary tract antiseptic activity. Nalidixic acid concentrates in the renal tubules and bladder and exerts its local antibacterial actions by interference of DNA gyrase activity, thereby inhibiting DNA synthesis during bacterial replication in a dose-dependent manner. Nalidixic acid is active against most gram-negative organisms that cause urinary tract infections.
NCI

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nalorfin

A narcotic antagonist with some agonist properties. It is an antagonist at mu opioid receptors and an agonist at kappa opioid receptors. Given alone it produces a broad spectrum of unpleasant effects and it is considered to be clinically obsolete.
MSH

narcotic antagonist with some agonist properties; an antagonist at mu opioid receptors and an agonist at kappa opioid receptors.
CSP

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naloxon

A specific opiate antagonist that has no agonist activity. It is a competitive antagonist at mu, delta, and kappa opioid receptors.
MSH

specific opiate antagonist with no agonist activity, a competitive antagonist at mu, delta, and kappa opioid receptors.
CSP

A thebaine derivate with competitive opioid antagonistic properties. Naloxone reverses the effects of opioid analgesics by binding to the opioid receptors in the CNS, and inhibiting the typical actions of opioid analgesics, including analgesia, euphoria, sedation, respiratory depression, miosis, bradycardia, and physical dependence. Naloxone binds to mu-opioid receptors with a high affinity, and a lesser degree to kappa- and gamma-opioid receptors in the CNS.
NCI

A substance that is being studied as a treatment for constipation caused by narcotic medications. It belongs to the family of drugs called narcotic antagonists.
NCI

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naltrexon

Derivative of noroxymorphone that is the N-cyclopropylmethyl congener of NALOXONE. It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and has been proposed for the treatment of heroin addiction. The FDA has approved naltrexone for the treatment of alcohol dependence.
MSH

synthetic congener of oxymorphone, chemically related to naloxone; a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and has been proposed for the treatment of heroin addiction and alcohol dependence.
CSP

A noroxymorphone derivative with competitive opioid antagonistic property. Naltrexone reverses the effects of opioid analgesics by binding to the various opioid receptors in the central nervous system, including the mu-, kappa- and gamma-opioid receptors. This leads to an inhibition of the typical actions of opioid analgesics, including analgesia, euphoria, sedation, respiratory depression, miosis, bradycardia, and physical dependence. Naltrexone is longer-acting and more potent compared to naloxone.
NCI

a drug used to help people who have a narcotic or alcohol addiction stay drug free
CHV

A drug that blocks the action of opiates (drugs used to treat pain). It may be used in the treatment of intravenous opiate addiction or alcohol dependence. Naltrexone is also being studied in the treatment of breast cancer. It may block the effects of the hormone estrogen, which causes some breast cancer cells to grow, or block the blood flow to tumors. It is a type of opiate antagonist.
NCI

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skupiny lidí – výčet

Persons as individuals (e.g., ABORTION APPLICANTS) or as members of a group (e.g., HISPANIC AMERICANS). It is not used for members of the various professions (e.g., PHYSICIANS) or occupations (e.g., LIBRARIANS) for which OCCUPATIONAL GROUPS is available.
MSH

Human beings in general.
NCI

A human being.
NCI

A living subject of the species homo sapiens.


HL7V3.0

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věkové skupiny

a general term for grouping human age group terms; prefer NTs.
CSP

Persons classified by age from birth (INFANT, NEWBORN) to octogenarians and older (AGED, 80 AND OVER).
MSH

Subgroups of populations based on age. (NCI)
NCI

Subgroups of populations based on age.
NCI

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skupiny lidí podle povolání

Members of the various professions (e.g., PHYSICIANS) or occupations (e.g., POLICE).
MSH

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jména

Personal names, given or surname, as cultural characteristics, as ethnological or religious patterns, as indications of the geographic distribution of families and inbreeding, etc. Analysis of isonymy, the quality of having the same or similar names, is useful in the study of population genetics. NAMES is used also for the history of names or name changes of corporate bodies, such as medical societies, universities, hospitals, government agencies, etc.
MSH

The words or language units by which a thing is known.
NCI

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Namibie

A republic in southern Africa, south of ANGOLA and west of BOTSWANA. Its capital is Windhoek.
MSH

A country in Southern Africa, bordering the South Atlantic Ocean, between Angola and South Africa. (NCI)
NCI

A country in Southern Africa, bordering the South Atlantic Ocean, between Angola and South Africa. (CIA World Factbook 2002)
NCI

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nandrolon

C18 steroid with androgenic and anabolic properties. It is generally prepared from alkyl ethers of ESTRADIOL to resemble TESTOSTERONE but less one carbon at the 19 position.
MSH

A synthetic, anabolic steroid analog of testosterone. Similar to testosterone, nortestosterone (19-Nortestosterone) binds to and activates specific nuclear receptors. This agent may be used for testosterone replacement therapy in hypogonadal men, in HIV-wasting syndrome, and in other conditions in order to increase nitrogen retention and fat-free muscle mass. (NCI04)
NCI

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nafazolin

An adrenergic vasoconstrictor agent used as a decongestant.
MSH

An imidazole derivative and a direct-acting sympathomimetic amine with vasoconstrictive activity. Upon ocular administration, naphazoline exerts its effect by acting on alpha-adrenergic receptors in the arterioles of the conjunctiva to produce vasoconstriction, resulting in decreased conjunctival congestion and diminished itching, irritation and redness.
NCI

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naftaceny

Polyacenes with four ortho-fused benzene rings in a straight linear arrangement. This group is best known for the subclass called TETRACYCLINES.
MSH

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Naphthalene

A white, volatile, solid polycyclic hydrocarbon with a strong mothball odor. Naphthalene is obtained from either coal tar or petroleum distillation and is primarily used to manufacture phthalic anhydride, but is also used in moth repellents. Exposure to naphthalene is associated with hemolytic anemia, damage to the liver and neurological system, cataracts and retinal hemorrhage. Naphthalene is reasonably anticipated to be a human carcinogen and may be associated with an increased risk of developing laryngeal and colorectal cancer. (NCI05)
NCI

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kyseliny naftalenoctové

Naphthalene derivatives containing the -CH2CCO2H radical at the 1-position, the 2-position, or both. Compounds are used as plant growth regulators to delay sprouting, exert weed control, thin fruit, etc.
MSH

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naftaleny

Two-ring crystalline hydrocarbons isolated from coal tar. They are used as intermediates in chemical synthesis, as insect repellents, fungicides, lubricants, preservatives, and, formerly, as topical antiseptics.
MSH

two-ring crystalline aromatic hydrocarbons isolated from coal tar; used as intermediates in chemical synthesis, as insect repellents, fungicides, lubricants, and preservatives.
CSP

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naftalensulfonany

A class of organic compounds that contains a naphthalene moiety linked to a sulfonic acid salt or ester.
MSH

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naftol-AS-D-esterasa

Hydrolytic enzyme activity used as a histocytochemical test for the presence of esterases in tissue. Substrate used is 3-hydroxy-4`-nitro-2-naphthanilide chloroacetate (naphthol AS-D).
MSH

A selective cytochemical monocyte marker.
NCI

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naftoly

Naphthalene derivatives carrying one or more hydroxyl (-OH) groups at any ring position. They are often used in dyes and pigments, as antioxidants for rubber, fats, and oils, as insecticides, in pharmaceuticals, and in numerous other applications.
MSH

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naftochinony

Naphthalene rings which contain two ketone moieties in any position. They can be substituted in any position except at the ketone groups.
MSH

naphthalene rings which contain two ketone moieties in any position.
CSP

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naftylvinylpyridin

4(1-Naphthylvinyl)pyridine hydrochloride. Cholinesterase inhibitor. Synonym: YuB 25.
MSH

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naproxen

An anti-inflammatory agent with analgesic and antipyretic properties. Both the acid and its sodium salt are used in the treatment of rheumatoid arthritis and other rheumatic or musculoskeletal disorders, dysmenorrhea, and acute gout.
MSH

6-methoxy-alpha-methyl-2-naphthaleneacetic acid; nonsteroidal antiinflammatory drug (NSAID); acts by inhibiting cyclooxygenase and thus prostaglandin synthesis; tocolytic oxytocin antagonist.
CSP

a drug that relieves pain, inflammation, and fever
CHV

A drug used to treat mild pain and the symptoms of arthritis and several other conditions. It is also being studied in the treatment of bone pain in patients with cancer. Naprosyn stops the body from making substances that cause pain and inflammation. It is a type of nonsteroidal anti-inflammatory drug (NSAID) and a type of cyclooxygenase inhibitor.
NCI

A propionic acid derivative and a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic activities. Naproxen inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. The resulting decrease in prostaglandin synthesis is responsible for the therapeutic effects of naproxen. Naproxen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=40222&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=40222&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C680″ NCI Thesaurus)
PDQ

A propionic acid derivative and a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic activities. Naproxen inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. The resulting decrease in prostaglandin synthesis is responsible for the therapeutic effects of naproxen. Naproxen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation.
NCI

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narcismus

A psychoanalytic term meaning self-love.
MSH

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narcistická porucha osobnosti

A disorder characterized by an enduring pattern of grandiose beliefs and arrogant behavior together with an overwhelming need for admiration and a lack of empathy for (and even exploitation of) others.
NCI

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