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névus pigmentový

A nevus containing melanin. The term is usually restricted to nevocytic nevi (round or oval collections of melanin-containing nevus cells occurring at the dermoepidermal junction of the skin or in the dermis proper) or moles, but may be applied to other pigmented nevi.
MSH

nevus containing melanin; usually restricted to nevocytic nevi (round or oval collections of melanin-containing nevus cells occurring at the dermoepidermal junction of the skin or in the dermis proper) or moles, but may be applied to other pigmented nevi.
CSP

A benign (not cancer) growth on the skin that is formed by a cluster of melanocytes (cells that make a substance called melanin, which gives color to skin and eyes). A mole is usually dark and may be raised from the skin.
NCI

A neoplasm composed of melanocytes that usually appears as a dark spot on the skin.
NCI

A nevus characterised by the presence of excessive pigment.
NCI

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New Brunswick

A province of eastern Canada, one of the Maritime Provinces with NOVA SCOTIA; PRINCE EDWARD ISLAND; and sometimes NEWFOUNDLAND AND LABRADOR. Its capital is Fredericton. It was named in honor of King George III, of the House of Hanover, also called Brunswick. (From Webster`s New Geographical Dictionary, 1988, p828 & Room, Brewer`s Dictionary of Names, 1992, p375)
MSH

A maritime province of eastern Canada. Its capital is Fredericton.
NCI

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New Caledonia

A group of islands in Melanesia constituting a French overseas territory. The group includes New Caledonia (the main island), Ile des Pins, Loyalty Island, and several other islet groups. The capital is Noumea. It was discovered by Captain Cook in 1774 and visited by various navigators, explorers, and traders from 1792 to 1840. Occupied by the French in 1853, it was set up as a penal colony 1864-94. In 1946 it was made a French overseas territory. It was named by Captain Cook with the 5th and 6th century A.D. Latin name for Scotland, Caledonia. (From Webster`s New Geographical Dictionary, 1988, p830 & Room, Brewer`s Dictionary of Names, 1992, p375)
MSH

A country in the Pacific, comprised of islands in the South Pacific Ocean, east of Australia. (NCI)
NCI

A country in the Pacific, comprised of islands in the South Pacific Ocean, east of Australia. (CIA World Factbook 2002)
NCI

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Nová Anglie

The geographic area of New England in general and when the specific state or states are not indicated. States usually included in this region are Maine, New Hampshire, Vermont, Massachusetts, Connecticut, and Rhode Island.
MSH

The area in the United States comprised of the following states: Maine, New Hampshire, Vermont, Massachusetts, Rhode Island, Connecticut, and New Jersey. (from SEERS 2004 codeset)
NCI

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Nová Guinea

Originally an island of the Malay Archipelago, the second largest island in the world. It divided, West New Guinea becoming part of Indonesia and East New Guinea becoming Papua New Guinea.
MSH

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New Hampshire

A state in the northeastern United States. Its capital is Concord.
NCI

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New Jersey

A state in the mid-atlantic United States. Its capital is Trenton.
NCI

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New Mexico

A state in the southwestern United States. Its capital is Santa Fe.
NCI

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Nový Jižní Wales

A state in southeastern Australia. Its capital is Sydney. It was discovered by Captain Cook in 1770 and first settled at Botany Bay by marines and convicts in 1788. It was named by Captain Cook who thought its coastline resembled that of South Wales. (From Webster`s New Geographical Dictionary, 1988, p840 & Room, Brewer`s Dictionary of Names, 1992, p377)
MSH

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New York

A state in the northeastern United States. Its capital is Albany.
NCI

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Nový Zéland

country in the southwestern Pacific comprising chiefly North and South Islands; capital Wellington; a dominion of the British Commonwealth.
CSP

A group of islands in the southwest Pacific. Its capital is Wellington. It was discovered by the Dutch explorer Abel Tasman in 1642 and circumnavigated by Cook in 1769. Colonized in 1840 by the New Zealand Company, it became a British crown colony in 1840 until 1907 when colonial status was terminated. New Zealand is a partly anglicized form of the original Dutch name Nieuw Zeeland, new sea land, possibly with reference to the Dutch province of Zeeland. (From Webster`s New Geographical Dictionary, 1988, p842 & Room, Brewer`s Dictionary of Names, 1992, p378)
MSH

A country in the Pacific, comprised of islands in the South Pacific Ocean, southeast of Australia. (NCI)
NCI

Description:Realm code for use of New Zealand


HL7V3.0

A country in the Pacific, comprised of islands in the South Pacific Ocean, southeast of Australia. (CIA World Factbook 2002)
NCI

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newcastleská nemoc

An acute febrile, contagious, viral disease of birds caused by an AVULAVIRUS called NEWCASTLE DISEASE VIRUS. It is characterized by respiratory and nervous symptoms in fowl and is transmissible to man causing a severe, but transient conjunctivitis.
MSH

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virus newcastleské nemoci

causes respiratory disease in many species of birds, with nasal discharge and diarrhea; may infect man, causing conjunctivitis; transmission in birds is by drinking water or dust.
CSP

The most well known avian paramyxovirus in the genus AVULAVIRUS and the cause of a highly infectious pneumoencephalitis in fowl. It is also reported to cause CONJUNCTIVITIS in humans. Transmission is by droplet inhalation or ingestion of contaminated water or food.
MSH

A bird virus that is being studied in the treatment of cancer. It may be used to kill cancer cells directly, or it may be given as a cancer vaccine to stimulate the body`s immune system. Newcastle disease virus is a type of biological response modifier and vaccine therapy.
NCI

A negative-stranded RNA virus that infects birds. It is the type strain for avian paramyxoviruses.
NCI

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Newfoundland

An island in the Atlantic Ocean, off the east coast of Canada, constituting with Labrador on the mainland, a province of Canada. The name describing a land just discovered was recorded by John Cabot in 1497. (From Webster`s New Geographical Dictionary, 1988, p831 & Room, Brewer`s Dictionary of Names, 1992, p376)
MSH

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noviny

Publications printed and distributed daily, weekly, or at some other regular and usually short interval, containing news, articles of opinion (as editorials and letters), features, advertising, and announcements of current interest. (Webster`s 3d ed)
MSH

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niacin

A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties.
MSH

nicotinic acid (3-pyridinecarboxylic acid) and its derivatives; a water soluble B vitamin which is the precursor of NAD and NADP.
CSP

Water-soluble vitamin that is a cosubstrate or coenzyme with numerous dehydrogenases for the transfer of the hydride ion. (DRI)
NCI

A water-soluble vitamin belonging to the vitamin B family, which occurs in many animal and plant tissues, with antihyperlipidemic activity. Niacin is converted to its active form niacinamide, which is a component of the coenzymes nicotinamide adenine dinucleotide (NAD) and its phosphate form, NADP. These coenzymes play an important role in tissue respiration and in glycogen, lipid, amino acid, protein, and purine metabolism. Although the exact mechanism of action by which niacin lowers cholesterol is not fully understood, it may act by inhibiting the synthesis of very low density lipoproteins (VLDL), inhibiting the release of free fatty acids from adipose tissue, increasing lipoprotein lipase activity, and reducing the hepatic synthesis of VLDL-C and LDL-C. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=38351&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=38351&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C689″ NCI Thesaurus)
PDQ

A water-soluble vitamin belonging to the vitamin B family, which occurs in many animal and plant tissues, with antihyperlipidemic activity. Niacin is converted to its active form niacinamide, which is a component of the coenzymes nicotinamide adenine dinucleotide (NAD) and its phosphate form, NADP. These coenzymes play an important role in tissue respiration and in glycogen, lipid, amino acid, protein, and purine metabolism. Although the exact mechanism of action by which niacin lowers cholesterol is not fully understood, it may act by inhibiting the synthesis of very low density lipoproteins (VLDL), inhibiting the release of free fatty acids from adipose tissue, increasing lipoprotein lipase activity, and reducing the hepatic synthesis of VLDL-C and LDL-C.
NCI

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nialamid

An MAO inhibitor that is used as an antidepressive agent.
MSH

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Nikaragua

A country in Central America, bordering both the Caribbean Sea and the North Pacific Ocean, between Costa Rica and Honduras. (NCI)
NCI

A country in Central America, bordering both the Caribbean Sea and the North Pacific Ocean, between Costa Rica and Honduras. (CIA World Factbook 2002)
NCI

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nikarbazin

An equimolar complex of 4,4`-Dinitrocarbanilide and 2-Hydroxy-4,6-dimethylpyrimidine. A coccidiostat for poultry.
MSH

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nikardipin

A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
MSH

1,4-dihydro-2,6-dimethyl-4-nitrophenyl-3, 5-pyridine carboxylic acid methyl-2- methylphenylmethylaminoethyl ester; calcium channel blocker of the nifedipine family; used clinically as a cerebral and coronary vasodilator.
CSP

A synthetic derivative of nitrophenyl-pyridine and potent calcium channel blocker, Nicardipine (Nifedipine Family) blocks calcium ions from certain cell walls and inhibits contraction of coronary and peripheral arteries, resulting in lowered oxygen requirements for heart muscle and decreased arterial contraction and spasm. It is used clinically as a cerebral and coronary vasodilator.
NCI

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nicergolin

An ergot derivative that has been used as a cerebral vasodilator and in peripheral vascular disease. It has been suggested to ameliorate cognitive deficits in cerebrovascular disease.
MSH

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niceritrol

An ester of nicotinic acid that lowers cholesterol and triglycerides in total plasma and in the VLD- and LD-lipoprotein fractions.
MSH

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nikl

A trace element with the atomic symbol Ni, atomic number 28, and atomic weight 58.69. It is a cofactor of the enzyme UREASE.
MSH

trace metallic element, symbol Ni, atomic number 28.
CSP

a kind of metallic element
CHV

An element with atomic symbol Ni, atomic number 28, and atomic weight 58.69.
NCI

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niklofolan

Proposed fasciolacide. Synonyms: Dertil; Bilevon; Bay 9015.
MSH

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niklosamid

An antihelmintic that is active against most tapeworms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p48)
MSH

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nikotinamidasa

An enzyme that catalyzes the hydrolysis of nicotinamide to nicotinate and ammonia. EC 3.5.1.19.
MSH

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niacinamid

An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and PELLAGRA. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.
MSH

B complex vitamin used in the prophylaxis and treatment of pellagra; functions as a component of the coenzyme NAD (Nicotinamide-Adenine Dinucleotide).
CSP

A nutrient in the vitamin B complex that the body needs in small amounts to function and stay healthy. Niacinamide helps some enzymes make energy in the cell. It is found in many plant and animal products. It is water-soluble (can dissolve in water) and must be taken in daily. It is being studied to increase the effect of radiation therapy on tumor cells.
NCI

A nutrient in the vitamin B complex that the body needs in small amounts to function and stay healthy. Niacin helps some enzymes work properly and helps skin, nerves, and the digestive tract stay healthy. Niacin is found in many plant and animal products. It is water-soluble (can dissolve in water) and must be taken in every day. Not enough niacin can cause a disease called pellagra (a condition marked by skin, nerve, and digestive disorders). A form of niacin is being studied in the prevention of skin and other types of cancer. Niacin may help to lower blood cholesterol.
NCI

The active form of vitamin B3 and a component of the coenzyme nicotinamide adenine dinucleotide (NAD). Niacinamide acts as a chemo- and radio-sensitizing agent by enhancing tumor blood flow, thereby reducing tumor hypoxia. This agent also inhibits poly(ADP-ribose) polymerases, enzymes involved in the rejoining of DNA strand breaks induced by radiation or chemotherapy. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=42044&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=42044&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C2327″ NCI Thesaurus)
PDQ

The active form of vitamin B3 and a component of the coenzyme nicotinamide adenine dinucleotide (NAD). Niacinamide acts as a chemo- and radio-sensitizing agent by enhancing tumor blood flow, thereby reducing tumor hypoxia. This agent also inhibits poly(ADP-ribose) polymerases, enzymes involved in the rejoining of DNA strand breaks induced by radiation or chemotherapy.
NCI

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nikotinamidmononukleotid

3-Carbamoyl-1-beta-D-ribofuranosyl pyridinium hydroxide-5`phosphate, inner salt. A nucleotide in which the nitrogenous base, nicotinamide, is in beta-N-glycosidic linkage with the C-1 position of D-ribose. Synonyms: Nicotinamide Ribonucleotide; NMN.
MSH

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nikotin

Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
MSH

very poisonous alkaloid; the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission; nicotine is important medically because of its presence in tobacco smoke, and is also used as an insecticide.
CSP

An addictive, poisonous chemical found in tobacco. It can also be made in the laboratory. When it enters the body, nicotine causes an increased heart rate and use of oxygen by the heart, and a sense of well-being and relaxation. It is also used as an insecticide.
NCI

A plant alkaloid, found in the tobacco plant, and addictive central nervous system (CNS) stimulant that causes either ganglionic stimulation in low doses or ganglionic blockage in high doses. Nicotine acts as an agonist at the nicotinic cholinergic receptors in the autonomic ganglia, at neuromuscular junctions, and in the adrenal medulla and the brain. Nicotine`s CNS-stimulating activities may be mediated through the release of several neurotransmitters, including acetylcholine, beta-endorphin, dopamine, norepinephrine, serotonin, and ACTH. As a result, peripheral vasoconstriction, tachycardia, and elevated blood pressure may be observed with nicotine intake. This agent may also stimulate the chemoreceptor trigger zone, thereby inducing nausea and vomiting. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=42243&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=42243&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C691″ NCI Thesaurus)
PDQ

A plant alkaloid, found in the tobacco plant, and addictive central nervous system (CNS) stimulant that causes either ganglionic stimulation in low doses or ganglionic blockage in high doses. Nicotine acts as an agonist at the nicotinic cholinergic receptors in the autonomic ganglia, at neuromuscular junctions, and in the adrenal medulla and the brain. Nicotine`s CNS-stimulating activities may be mediated through the release of several neurotransmitters, including acetylcholine, beta-endorphin, dopamine, norepinephrine, serotonin, and ACTH. As a result, peripheral vasoconstriction, tachycardia, and elevated blood pressure may be observed with nicotine intake. This agent may also stimulate the chemoreceptor trigger zone, thereby inducing nausea and vomiting.
NCI

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kyseliny nikotinové

2-, 3-, or 4-Pyridinecarboxylic acids. Pyridine derivatives substituted with a carboxy group at the 2-, 3-, or 4-position. The 3-carboxy derivative (NIACIN) is active as a vitamin.
MSH

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