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nitrazepam

A benzodiazepine derivative used as an anticonvulsant and hypnotic.
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nitrendipin

A calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.
MSH

1,4-dihydro-2,6-dimethyl-4- nitrophenyl-3,5-pyridine carboxyic acid ethylmethyl ester; calcium channel blocker of the nifedipine family.
CSP

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oxid dusnatý

A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.
MSH

NO; originally found as an intercellular messenger molecule in vascular smooth muscle, where it has a relaxant, vasodilatory effect; formed by oxidation of arginine with citrulline as side product; in nervous tissue, may be part of glutamate-calcium-cGMP signal transduction system.
CSP

name of an inorganic chemical
CHV

An unstable free-radical gas which reacts rapidly with oxygen to form nitrogen oxides. Water soluble, NO is produced normally in numerous tissues and is considered to be a mediator of cell-to cell communication; it functions in numerous processes including vasodilation, inflammation, and neurotransmission. (NCI04)
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nitrily

Organic compounds containing the -CN radical. The concept is distinguished from CYANIDES, which denotes inorganic salts of HYDROGEN CYANIDE.
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kyselina nitrilotrioctová

A derivative of acetic acid, N(CH2COOH)3. It is a complexing (sequestering) agent that forms stable complexes with Zn2+. (From Miall`s Dictionary of Chemistry, 5th ed.)
MSH

A white, crystalline solid compound. Nitrilotriacetic acid is mainly used as a chelating and eluting agent and is found in laundry detergents. Exposure to Nitrilotriacetic acid irritates the skin, eyes and respiratory tract and causes kidney and bladder damage. Nitrilotriacetic acid is reasonably anticipated to be a human carcinogen. (NCI05)
NCI

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nitritreduktasy

A group of enzymes that oxidize diverse nitrogenous substances to yield nitrite. (Enzyme Nomenclature, 1992) EC 1.
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dusitany

Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh`s Chemical Dictionary, 5th ed)
MSH

the anion NO2-.
CSP

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dusíkaté sloučeniny

Compounds having the nitro group, -NO2, attached to carbon. When attached to nitrogen they are nitramines and attached to oxygen they are NITRATES.
MSH

compound containing the chemical group N02.
CSP

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nitroanisol-O-demethylasa

Oxidative enzyme which transforms p-nitroanisole into p-nitrophenol.
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Nitrobacter

A genus of gram-negative, rod-shaped bacteria that oxidizes nitrites to nitrates. Its organisms occur in aerobic environments where organic matter is being mineralized, including soil, fresh water, and sea water.
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Nitrobacteraceae

A obsolete family name of gram-negative, aerobic bacteria which derive energy from the oxidation of ammonia to nitrite or nitrite to nitrate. Its organisms are commonly found in soil and fresh water.
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nitrobenzene

benzene derivatives containing a nitro (NO2) group.
CSP

A yellowish, oily, aromatic nitro-compound with an almond-like odor that emits toxic fumes of nitrogen oxides upon combustion. Nitrobenzene is primarily used in the manufacture of aniline, but is also used in the manufacture of lubricating oils, dyes, drugs, pesticides, and synthetic rubber. Exposure to nitrobenzene irritates the skin, eyes and respiratory tract and can result in methemoglobinemia causing fatigue, dyspnea, dizziness, disturbed vision, shortness of breath, collapse and even death. Nitrobenzene also damages the liver, spleen, kidneys and central nervous system. This substance is a possible mutagen and is reasonably anticipated to be a human carcinogen. (NCI05)
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nitrobenzoany

Benzoic acid or benzoic acid esters substituted with one or more nitro groups.
MSH

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tetrazoliová modř

Colorless to yellow dye that is reducible to blue or black formazan crystals by certain cells; formerly used to distinguish between nonbacterial and bacterial diseases, the latter causing neutrophils to reduce the dye; used to confirm diagnosis of chronic granulomatous disease.
MSH

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nitrofurantoin

A urinary anti-infective agent effective against most gram-positive and gram-negative organisms. Although sulfonamides and antibiotics are usually the agents of choice for urinary tract infections, nitrofurantoin is widely used for prophylaxis and long-term suppression.
MSH

A synthetic derivative of imidazolidinedione, Nitrofurantoin inhibits bacterial DNA, RNA, and cell wall protein synthesis. Activated by bacterial flavoproteins to intermediates that inactivate bacterial ribosomal proteins, Nitrofurantoin is used prophylactically as a urinary anti-infective agent against most gram-positive and gram-negative organisms and for long-term suppression of infections. (NCI04)
NCI

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nitrofurazon

A topical anti-infective agent effective against gram-negative and gram-positive bacteria. It is used for superficial WOUNDS AND INJURIES and skin infections. Nitrofurazone has also been administered orally in the treatment of TRYPANOSOMIASIS.
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dusík

An element with the atomic symbol N, atomic number 7, and atomic weight [14.00643; 14.00728]. Nitrogen exists as a diatomic gas and makes up about 78% of the earth`s atmosphere by volume. It is a constituent of proteins and nucleic acids and found in all living cells.
MSH

use this term only for the element N or the gas N2; for other nitrogen compounds see NITROGEN COMPOUND.
CSP

An element with atomic symbol N, atomic number 7, and atomic weight 14.01.
NCI

name of a chemical element (atomic number 7)
CHV

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dusík – sloučeniny

Inorganic compounds that contain nitrogen as an integral part of the molecule.
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oxid dusičitý

Nitrogen oxide (NO2). A highly poisonous gas. Exposure produces inflammation of lungs that may only cause slight pain or pass unnoticed, but resulting edema several days later may cause death. (From Merck, 11th ed) It is a major atmospheric pollutant that is able to absorb UV light that does not reach the earth`s surface.
MSH

Found in the atmosphere as a key ingredient in photochemical formation of smog and acid rain, Nitrogen Dioxide is a poisonous gas that forms during combustion. Toxic at high concentrations, it reacts with moisture in the air to form nitric acid, highly corrosive and hazardous to plants and animals. (NCI04)
NCI

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dusík – fixace

The process in certain BACTERIA; FUNGI; and CYANOBACTERIA converting free atmospheric NITROGEN to biologically usable forms of nitrogen, such as AMMONIA; NITRATES; and amino compounds.
MSH

ability of certain bacteria, fungi and blue-green algae to convert free atmospheric nitrogen to biologically usable forms such as ammonia, nitrates, or amino groups.
CSP

The process in which nitrogen is taken from its relatively inert molecular form (N2) in the atmosphere and converted into nitrogen compounds useful for other chemical processes, such as ammonia, nitrate and nitrogen dioxide. [Wikipedia:Nitrogen_fixation]
GO

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dusík – isotopy

Stable nitrogen atoms that have the same atomic number as the element nitrogen, but differ in atomic weight. N-15 is a stable nitrogen isotope.
MSH

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dusíkaté hořčičné sloučeniny

A group of alkylating agents derived from mustard gas, with the sulfur replaced by nitrogen. They were formerly used as toxicants and vesicants, but now function as antineoplastic agents. These compounds are also powerful mutagens, teratogens, immunosuppressants, and carcinogens.
MSH

A mustard agent containing nitrogen and chlorine atoms.
NCI

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oxidy dusíku

Inorganic oxides that contain nitrogen.
MSH

header term for class of oxides that contain nitrogen.
CSP

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dusík – radioisotopy

Unstable isotopes of nitrogen that decay or disintegrate emitting radiation. N atoms with atomic weights 12, 13, 16, 17, and 18 are radioactive nitrogen isotopes.
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nitrogenasa

An enzyme system that catalyzes the fixing of nitrogen in soil bacteria and blue-green algae (CYANOBACTERIA). EC 1.18.6.1.
MSH

an iron-molybdenum protein which catalyzes the reduction (“fixation”) of molecular nitrogen to ammonia in many plants and microorganisms, using reduced ferredoxin and ATP.
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nitrohydroxyjodfenylacetát

Also called 4-hydroxy-3-iodo-5-nitrophenylacetate. A haptenic determinant that can be radiolabeled and used as salts and derivatives for investigations of immunogenic specificity studies.
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nitromifen

A non-steroidal estrogen antagonist (as the 1:1 citrate) most commonly used as a research tool in animal studies.
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Nitrophenol

any organic compound containing one or more hydroxyl groups and nitro groups attached to a benzene ring.
CSP

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4-nitrofenylfosfatasa

An enzyme that catalyzes the hydrolysis of nitrophenyl phosphates to nitrophenols. At acid pH it is probably ACID PHOSPHATASE (EC 3.1.3.2); at alkaline pH it is probably ALKALINE PHOSPHATASE (EC 3.1.3.1). EC 3.1.3.41.
MSH

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nitrofenylgalaktosidy

Includes ortho-, meta-, and para-nitrophenylgalactosides.
MSH

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