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fenestrace

The surgical creation of a new opening in the labyrinth of the ear for the restoration of hearing in cases of OTOSCLEROSIS. (Dorland, 27th ed)
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fenfluramin

A centrally active drug that apparently both blocks serotonin uptake and provokes transport-mediated serotonin release.
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centrally active phenethylamine that apparently both blocks serotonin uptake and provokes transport-mediated serotonin release.
CSP

An amphetamine derivative and a sympathomimetic stimulant with appetite-suppressant property. Fenfluramine, which was part of the Fen-Phen anti-obesity medication, stimulates the release of serotonin from vesicular storage, and modulates serotonin transporter function. Since serotonin regulates mood and appetite, among other functions, increased serotonin level results in a feeling of fullness and loss of appetite.
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fenitrothion

An organothiophosphate cholinesterase inhibitor that is used as an insecticide.
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fenoprofen

An anti-inflammatory analgesic and antipyretic highly bound to plasma proteins. It is pharmacologically similar to ASPIRIN, but causes less gastrointestinal bleeding.
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A propionic acid derivative with analgesic, non-steroidal antiinflammatory and antirheumatic properties. Fenoprofen inhibits both isozymes of cyclooxygenase; resulting in prostaglandin synthesis inhibition, thereby blocking the conversion of arachidonic acid to prostaglandins. In addition, fenoprofen activates both peroxisome proliferator activated receptors (PPAR)-alpha and -gamma, by which it may down-regulate leukotriene B4 production.
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fenoterol

An adrenergic beta-2 agonist that is used as a bronchodilator and tocolytic.
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A short-acting sympathomimetic agent with bronchodilator activity. Fenoterol stimulates beta-2-adrenergic receptors in the lungs, thereby activating the enzyme adenylate cyclase that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3`,5`-adenosine monophosphate (cAMP). Increased cAMP concentrations relax bronchial smooth muscle, relieve bronchospasms, and reduce inflammatory cell mediator release, especially from mast cells.
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fentanyl

A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
MSH

potent narcotic analgesic, abuse of which leads to habituation or addiction; primarily a mu-opioid agonist, used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance.
CSP

a kind of narcotic pain relieving drug
CHV

A synthetic, lipophilic phenylpiperidine opioid agonist with analgesic and anesthetic properties. Fentanyl selectively binds to the mu-receptor in the central nervous system (CNS) thereby mimicking the effects of endogenous opiates. Stimulation of the mu-subtype opioid receptor stimulates the exchange of GTP for GDP on the G-protein complex and subsequently inhibits adenylate cyclase. This results in a decrease in intracellular cAMP and leads to a reduction in the release of neurotransmitters such as substance P, GABA, dopamine, acetylcholine and noradrenaline. The analgesic effect of fentanyl is likely due to its metabolite morphine, which induces opening of G-protein-coupled inwardly rectifying potassium (GIRK) channels and blocks the opening of N-type voltage-gated calcium channels, thereby resulting in hyperpolarization and reduced neuronal excitability.
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fenthion

Potent cholinesterase inhibitor used as an insecticide and acaricide.
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fermentace

Anaerobic degradation of GLUCOSE or other organic nutrients to gain energy in the form of ATP. End products vary depending on organisms, substrates, and enzymatic pathways. Common fermentation products include ETHANOL and LACTIC ACID.
MSH

enzyme-induced chemical change in organic compounds that takes place in the absence of oxygen; the change usually results in the production of carbon dioxide, ethanol or lactic acid, and the production of energy.
CSP

The anaerobic enzymatic conversion of organic compounds, especially carbohydrates, to other compounds, especially to ethyl alcohol, yielding energy in the form of adenosine triphosphate (ATP). [GOC:curators, MetaCyc:Fermentation]
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fermium

Fermium. A man-made radioactive actinide with atomic symbol Fm, atomic number 100, and atomic weight 257. Its known isotopes range from 244-254 and 256-258. Its valence can be +2 or +3. Like einsteinium, it was discovered in 1952 in the debris from a thermonuclear explosion.
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ferredoxin-NADP-reduktasa

An enzyme that catalyzes the oxidation and reduction of FERREDOXIN or ADRENODOXIN in the presence of NADP. EC 1.18.1.2 was formerly listed as EC 1.6.7.1 and EC 1.6.99.4.
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ferredoxiny

Iron-containing proteins that transfer electrons, usually at a low potential, to flavoproteins; the iron is not present as in heme. (McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
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iron containing proteins that transfer electrons, usually at a low potential, to flavoproteins.
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fretky

Semidomesticated variety of European polecat much used for hunting RODENTS and/or RABBITS and as a laboratory animal. It is in the subfamily Mustelinae, family MUSTELIDAE.
MSH

animal of the weasel family (Mustela or Putorius furo), about fourteen inches in length.
CSP

A small domestic mammal of the type Mustela putorious, with an elongated body and brown, black, white, or mixed fur. The ferret is carnivorous and crepuscular, spending 14-18 hours a day sleeping. This animal is prone to adrenal cancers, insulinoma, and lymphoma. In pre-clinical research, the ferret is used most commonly in toxicological screening and studies involving human influenza virus, as well as studies in reproductive physiology, anatomy, endocrinology and neuroscience.
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železité sloučeniny

Inorganic or organic compounds containing trivalent iron.
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ferrichrom

A cyclic peptide consisting of three residues of delta-N-hydroxy-delta-N-acetylornithine. It acts as an iron transport agent in Ustilago sphaerogena.
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ferrikyanidy

Inorganic salts of the hypothetical acid, H3Fe(CN)6.
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Ferrihaem

porphyrin chelate of iron.
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ferritin

iron containing protein complex that is formed by a combination of ferric iron with the protein apoferritin; one of the chief forms in which iron is stored in the body.
CSP

Iron-containing proteins that are widely distributed in animals, plants, and microorganisms. Their major function is to store IRON in a nontoxic bioavailable form. Each ferritin molecule consists of ferric iron in a hollow protein shell (APOFERRITINS) made of 24 subunits of various sequences depending on the species and tissue types.
MSH

a protein that stores iron
CHV

An iron protein complex, containing up to 23% iron, formed by the union of ferric iron with apoferritin; it is found in the intestinal mucosa, spleen, bone marrow, reticulocytes, and liver, and regulates iron storage and transport from the intestinal lumen to plasma.
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ferrochelatasa

A mitochondrial enzyme found in a wide variety of cells and tissues. It is the final enzyme in the 8-enzyme biosynthetic pathway of HEME. Ferrochelatase catalyzes ferrous insertion into protoporphyrin IX to form protoheme or heme. Deficiency in this enzyme results in ERYTHROPOIETIC PROTOPORPHYRIA.
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ferrokyanidy

Inorganic salts of the hypothetical acid ferrocyanic acid (H4Fe(CN)6).
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železnaté sloučeniny

Inorganic or organic compounds that contain divalent iron.
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ferrozin

A ferroin compound that forms a stable magenta-colored solution with the ferrous ion. The complex has an absorption peak at 562 nm and is used as a reagent and indicator for iron.
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plodné dny

The period in the MENSTRUAL CYCLE that is optimal for FERTILIZATION of the OVUM and yielding PREGNANCY. The duration of fertile period depends on the life span of male GAMETES within the female reproductive tract and the time of OVULATION. It usually begins a few days before ovulation and ends on the day of ovulation.
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fertilita

The capacity to conceive or to induce conception. It may refer to either the male or female.
MSH

capacity to conceive or to induce conception; may refer to either male or female.
CSP

The ability to produce children.
NCI

Able to produce children.
NCI

The capacity to conceive or to induce conception. It may refer to either the male or female. (MeSH)
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fertilizující látky

Drugs used to increase fertility or to treat infertility.
MSH

drugs used to increase fertility or to treat infertility in either males or females.
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fertilizující látky ženské

Compounds which increase the capacity to conceive in females.
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fertilizující látky mužské

Compounds which increase the capacity of the male to induce conception.
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Fertility Rate

Births in 1 year x 1,000/number of women aged 15-44 at midyear.
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fertilizace

The fusion of a spermatozoon (SPERMATOZOA) with an OVUM thus resulting in the formation of a ZYGOTE.
MSH

fusion of a spermatozoan with an ovum resulting in the formation of a zygote.
CSP

The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy). [GOC:tb, ISBN:0198506732 “Oxford Dictionary of Biochemistry and Molecular Biology”]
GO

The process beginning with penetration of the secondary oocyte by the spermatozoon and completed by fusion of the male and female pronuclei.
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fertilizace in vitro

An assisted reproductive technique that includes the direct handling and manipulation of oocytes and sperm to achieve fertilization in vitro.
MSH

assisted reproductive technique that includes the direct handling and manipulation of oocytes and sperm to achieve fertilization in vitro.
CSP

a process whereby (usually multiple) ova are placed in a medium to which sperm are added for fertilization, the zygote thus produced is then introduced in the uterus.
CSP

A procedure in which eggs are removed from a woman`s ovary and combined with sperm outside the body to form embryos. The embryos are grown in the laboratory for several days and then either placed in a woman`s uterus or cryopreserved (frozen) for future use.
NCI

Fertilization of an ovum outside of the body.
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hnojiva průmyslová

Substances or mixtures that are added to the soil to supply nutrients or to make available nutrients already present in the soil, in order to increase plant growth and productivity.
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