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peptidy – elongační faktor Tu

A protein found in bacteria and eukaryotic mitochondria which delivers aminoacyl-tRNA`s to the A site of the ribosome. The aminoacyl-tRNA is first bound to a complex of elongation factor Tu containing a molecule of bound GTP. The resulting complex is then bound to the 70S initiation complex. Simultaneously the GTP is hydrolyzed and a Tu-GDP complex is released from the 70S ribosome. The Tu-GTP complex is regenerated from the Tu-GDP complex by the Ts elongation factor and GTP.
MSH

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peptidy – elongační faktory

Protein factors uniquely required during the elongation phase of protein synthesis.
MSH

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peptidy – fragmenty

Partial proteins formed by partial hydrolysis of complete proteins or generated through PROTEIN ENGINEERING techniques.
MSH

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peptidhydrolasy

Hydrolases that specifically cleave the peptide bonds found in PROTEINS and PEPTIDES. Examples of sub-subclasses for this group include EXOPEPTIDASES and ENDOPEPTIDASES.
MSH

Enzymes produced and secreted by the pancreas which aid in the proteolysis of proteins in the digestive tract. Pancreatic proteolytic enzymes include trypsin, chymotrypsin and carboxypeptidase; these enzymes are secreted as zymogens, inactive precursors of the enzymes, and are activated in the lumen of the digestive canal. Another proteolytic enzyme, enteropeptidase, is associated with the brush border of enterocytes; this enzyme catalyses the conversion of trypsinogen into trypsin which, in turn, can activate a number of other pancreatic zymogens. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=43492&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=43492&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C38728″ NCI Thesaurus)
PDQ

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peptidy – faktory zahájení

Protein factors uniquely required during the initiation phase of protein synthesis in GENETIC TRANSLATION.
MSH

One of several soluble proteins involved in the initiation of protein or RNA synthesis. (On-line Medical Dictionary)
NCI

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peptidy – mapování

Analysis of PEPTIDES that are generated from the digestion or fragmentation of a protein or mixture of PROTEINS, by ELECTROPHORESIS; CHROMATOGRAPHY; or MASS SPECTROMETRY. The resulting peptide fingerprints are analyzed for a variety of purposes including the identification of the proteins in a sample, GENETIC POLYMORPHISMS, patterns of gene expression, and patterns diagnostic for diseases.
MSH

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endopeptidasy

A subclass of PEPTIDE HYDROLASES that catalyze the internal cleavage of PEPTIDES or PROTEINS.
MSH

nonEC category which corresponds to EC 3.4.21, EC 3.4.22, EC 3.4.23, EC 3.4.24, and EC 3.4.99.
CSP

A class of enzymes that catalyze the hydrolysis of peptide bonds in the interior of a polypeptide chain or protein molecule.
NCI

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peptid fí

A 27-amino acid peptide with histidine at the N-terminal and isoleucine amide at the C-terminal. The exact amino acid composition of the peptide is species dependent. The peptide is secreted in the intestine, but is found in the nervous system, many organs, and in the majority of peripheral tissues. It has a wide range of biological actions, affecting the cardiovascular, gastrointestinal, respiratory, and central nervous systems.
MSH

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peptidsynthasy

Ligases that catalyze the joining of adjacent AMINO ACIDS by the formation of carbon-nitrogen bonds between their carboxylic acid groups and amine groups.
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peptid T

N-(N-(N(2)-(N-(N-(N-(N-D-Alanyl L-seryl)-L-threonyl)-L-threonyl) L-threonyl)-L-asparaginyl)-L-tyrosyl) L-threonine. Octapeptide sharing sequence homology with HIV envelope protein gp120. It is potentially useful as antiviral agent in AIDS therapy. The core pentapeptide sequence, TTNYT, consisting of amino acids 4-8 in peptide T, is the HIV envelope sequence required for attachment to the CD4 receptor.
MSH

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peptidy – faktory ukončení

Proteins that are involved in the peptide chain termination reaction (PEPTIDE CHAIN TERMINATION, TRANSLATIONAL) on RIBOSOMES. They include codon-specific class-I release factors, which recognize stop signals (TERMINATOR CODON) in the MESSENGER RNA; and codon-nonspecific class-II release factors.
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peptidy

Members of the class of compounds composed of AMINO ACIDS joined together by peptide bonds between adjacent amino acids into linear, branched or cyclical structures. OLIGOPEPTIDES are composed of approximately 2-12 amino acids. Polypeptides are composed of approximately 13 or more amino acids. PROTEINS are linear polypeptides that are normally synthesized on RIBOSOMES.
MSH

chemical bond with the structure -CO-CHR-NH-; in biochemistry, polymers of alpha-aminoacids joined by peptide bonds.
CSP

a kind of chemical compound
CHV

A compound of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. Peptides are smaller than proteins and the dividing line is around 50 amino acids.
NCI

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peptidy cyklické

Peptides whose amino and carboxy ends are linked together with a peptide bond forming a circular chain. Some of them are ANTI-INFECTIVE AGENTS. Some of them are biosynthesized non-ribosomally (PEPTIDE BIOSYNTHESIS, NON-RIBOSOMAL).
MSH

any peptide containing a ring structure.
CSP

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peptidoglykan

polysaccharide covalently linked to crosslinked peptides to form a matrix found in bacterial cell walls.
CSP

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peptidyltransferasy

Acyltransferases that use AMINO ACYL TRNA as the amino acid donor in formation of a peptide bond. There are ribosomal and non-ribosomal peptidyltransferases.
MSH

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Peptococcaceae

A family of bacteria found in the mouth and intestinal and respiratory tracts of man and other animals as well as in the human female urogenital tract. Its organisms are also found in soil and on cereal grains.
MSH

A taxonomic family of bacterium in the phylum Firmicutes that includes the genera Dehalobacter, Peptococcus and Thermincola, among others.
NCI

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Peptococcus

A genus of gram-positive, anaerobic, coccoid bacteria that is part of the normal flora of the mouth, upper respiratory tract, and large intestine in humans. Its organisms cause infections of soft tissues and bacteremias.
MSH

A genus of anaerobic, Gram positive, cocci shaped bacterium assigned to the phylum Firmicutes and the family Peptococcaceae.
NCI

Any bacteria that is not assigned to the species level but can be assigned to the Peptococcus genus level.
NCI

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peptony

Derived proteins or mixtures of cleavage products produced by the partial hydrolysis of a native protein either by an acid or by an enzyme. Peptones are readily soluble in water, and are not precipitable by heat, by alkalis, or by saturation with ammonium sulfate. (Dorland, 28th ed)
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Peptostreptococcus

A genus of gram-positive, anaerobic, coccoid bacteria that is part of the normal flora of humans. Its organisms are opportunistic pathogens causing bacteremias and soft tissue infections.
MSH

A genus of anaerobic, Gram positive, cocci shaped bacterium assigned to the phylum Firmicutes and the family Peptostreptococcaceae.
NCI

Any bacteria that is not assigned to the species level but can be assigned to the Peptostreptococcus genus level.
NCI

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kyselina peroctová

A liquid that functions as a strong oxidizing agent. It has an acrid odor and is used as a disinfectant.
MSH

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perazin

A phenothiazine antipsychotic with actions and uses similar to those of CHLORPROMAZINE. Extrapyramidal symptoms may be more common than other side effects.
MSH

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percepce

The process by which the nature and meaning of sensory stimuli are recognized and interpreted.
MSH

The process of producing an internal, conscious image through stimulating a sensory system; it involves the recognition that stimulation has occurred, and the ability to discriminate various aspects of the stimulus.
NCI

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percepční uzavřenost

The tendency to perceive an incomplete pattern or object as complete or whole. This includes the Gestalt Law of Closure.
MSH

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percepční obrana

Selective perceiving such that the individual protects himself from becoming aware of something unpleasant or threatening, e.g., obscene words are not heard correctly, or violent acts are not seen accurately.
MSH

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percepční poruchy

Cognitive disorders characterized by an impaired ability to perceive the nature of objects or concepts through use of the sense organs. These include spatial neglect syndromes, where an individual does not attend to visual, auditory, or sensory stimuli presented from one side of the body.
MSH

cognitive disorders characterized by an impaired ability to perceive the nature of objects or concepts through use of the sense organs; includes spatial neglect syndromes, where an individual does not attend to visual, auditory, or sensory stimuli presented from one side of the body.
CSP

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percepce – deformace

lack of correspondence between the way a stimulus is commonly perceived and the way an individual perceives it under given conditions.
CSP

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percepční maskování

The interference of one perceptual stimulus with another causing a decrease or lessening in perceptual effectiveness.
MSH

interference of one perceptual stimulus with another causing a decrease or lessening in perceptual effectiveness; frequently associated with visual and auditory perception.
CSP

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kyselina chloristá

An oxidizing agent that is used in ANALYTICAL CHEMISTRY TECHNIQUES for separation of potassium from sodium. (From Merck Index, 11th ed)
MSH

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Perciformes

The most diversified of all fish orders and the largest vertebrate order. It includes many of the commonly known fish such as porgies, croakers, sunfishes, dolphin fish, mackerels, TUNA, etc.
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perkuse

Act of striking a part with short, sharp blows as an aid in diagnosing the condition beneath the sound obtained.
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