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CDPdiacylglycerolserin-O-fosfatidyltransferasa

An enzyme that catalyzes the formation of phosphatidylserine and CMP from CDPdiglyceride plus serine. EC 2.7.8.8.
MSH

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fosfatidylseriny

Derivatives of phosphatidic acids in which the phosphoric acid is bound in ester linkage to a serine moiety. Complete hydrolysis yields 1 mole of glycerol, phosphoric acid and serine and 2 moles of fatty acids.
MSH

derivatives of phosphatidic acids in which the phosphoric acid is bound in ester linkage to a serine moiety.
CSP

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fosfeny

A subjective visual sensation with the eyes closed and in the absence of light. Phosphenes can be spontaneous, or induced by chemical, electrical, or mechanical (pressure) stimuli which cause the visual field to light up without optical inputs.
MSH

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fosfiny

Inorganic or organic compounds derived from phosphine (PH3) by the replacement of H atoms. (From Grant & Hackh`s Chemical Dictionary, 5th ed)
MSH

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kyseliny fosfinové

Inorganic or organic derivatives of phosphinic acid, H2PO(OH). They include phosphinates and phosphinic acid esters.
MSH

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3-deoxy-7-fosfoheptulonátsynthasa

An enzyme that catalyzes the formation of 7-phospho-2-keto-3-deoxy-D-arabinoheptonate from phosphoenolpyruvate and D-erythrose-4-phosphate. It is one of the first enzymes in the biosynthesis of TYROSINE and PHENYLALANINE. This enzyme was formerly listed as EC 4.1.2.15.
MSH

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fosfoadenosinfosfosulfát

3`-Phosphoadenosine-5`-phosphosulfate. Key intermediate in the formation by living cells of sulfate esters of phenols, alcohols, steroids, sulfated polysaccharides, and simple esters, such as choline sulfate. It is formed from sulfate ion and ATP in a two-step process. This compound also is an important step in the process of sulfur fixation in plants and microorganisms.
MSH

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fosfokreatin

An endogenous substance found mainly in skeletal muscle of vertebrates. It has been tried in the treatment of cardiac disorders and has been added to cardioplegic solutions. (Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1996)
MSH

endogenous substance found mainly in skeletal muscle of vertebrates; it has been tried in the treatment of cardiac disorders and has been added to cardioplegic solutions.
CSP

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fosfodiesterasa – inhibitory

Compounds which inhibit or antagonize the biosynthesis or actions of phosphodiesterases.
MSH

any substance or agent which suppresses, prevents or opposes the actions or biosynthesis of phosphodiesterases.
CSP

Any agent that inhibits the activity of any of the phosphodiesterase subtypes that catalyze the breakdown of 3`,5`-cyclic adenosine monophosphate (cAMP) and/or 3`,5`-cyclic guanosine monophosphate (cGMP).
NCI

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fosfodiesterasy

A class of enzymes that catalyze the hydrolysis of one of the two ester bonds in a phosphodiester compound. EC 3.1.4.
MSH

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fosfoenolpyruvát

high energy compound that is a phosphorylated ester of the enol form of pyruvate; it is an intermediate in the Embden-Meyerhof pathway of glucose metabolism, in gluconeogenesis, and in the synthesis of some amino acids.
CSP

a kind of biological substance
CHV

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fosfoenolpyruvátkarboxykinasa (závislá na GTP)

An enzyme of the lyase class that catalyzes the conversion of GTP and oxaloacetate to GDP, phosphoenolpyruvate, and carbon dioxide. This reaction is part of gluconeogenesis in the liver. The enzyme occurs in both the mitochondria and cytosol of mammalian liver. (From Dorland, 27th ed) EC 4.1.1.32.
MSH

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fosfoenolpyruvátkarboxylasa

An enzyme with high affinity for carbon dioxide. It catalyzes irreversibly the formation of oxaloacetate from phosphoenolpyruvate and carbon dioxide. This fixation of carbon dioxide in several bacteria and some plants is the first step in the biosynthesis of glucose. EC 4.1.1.31.
MSH

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fosfoenolpyruvát-cukr-fosfotransferasový systém

The bacterial sugar phosphotransferase system (PTS) that catalyzes the transfer of the phosphoryl group from phosphoenolpyruvate to its sugar substrates (the PTS sugars) concomitant with the translocation of these sugars across the bacterial membrane. The phosphorylation of a given sugar requires four proteins, two general proteins, Enzyme I and HPr and a pair of sugar-specific proteins designated as the Enzyme II complex. The PTS has also been implicated in the induction of synthesis of some catabolic enzyme systems required for the utilization of sugars that are not substrates of the PTS as well as the regulation of the activity of adenylate cyclase. EC 2.7.1.-.
MSH

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fosfofruktokinasa-1

An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-1,6-bisphosphate. D-tagatose- 6-phosphate and sedoheptulose-7-phosphate also are acceptors. UTP, CTP, and ITP also are donors. In human phosphofructokinase-1, three types of subunits have been identified. They are PHOSPHOFRUCTOKINASE-1, MUSCLE TYPE; PHOSPHOFRUCTOKINASE-1, LIVER TYPE; and PHOSPHOFRUCTOKINASE-1, TYPE C; found in platelets, brain, and other tissues.
MSH

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fosfoglukomutasa

An enzyme that catalyzes the conversion of alpha D-glucose 1-phosphate to alpha D-glucose 6-phosphate. EC 5.4.2.2.
MSH

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fosfoglukonátdehydrogenasa

An enzyme of the oxidoreductase class that catalyzes the reaction 6-phospho-D-gluconate and NADP+ to yield D-ribulose 5-phosphate, carbon dioxide, and NADPH. The reaction is a step in the pentose phosphate pathway of glucose metabolism. (From Dorland, 27th ed) EC 1.1.1.43.
MSH

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fosfoglycerátkinasa

An enzyme catalyzing the transfer of a phosphate group from 3-phospho-D-glycerate in the presence of ATP to yield 3-phospho-D-glyceroyl phosphate and ADP. EC 2.7.2.3.
MSH

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fosfoglyceromutasa

An enzyme that catalyzes the conversion of 2-phospho-D-glycerate to 3-phospho-D-glycerate. EC 5.4.2.1.
MSH

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fosfolipasy A1

A phospholipase that hydrolyzes the acyl group attached to the 1-position of PHOSPHOGLYCERIDES.
MSH

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fosfolipasy A2

Phospholipases that hydrolyzes the acyl group attached to the 2-position of PHOSPHOGLYCERIDES.
MSH

Various types of calcium-dependent or -independent Phospholipases A2 hydrolyze phospholipids. Group I, II, and III phospholipases are secreted, while group IV phospholipases are cytosolic. The best characterized phospholipases are group II. (NCI)
NCI

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fosfolipasa C

An enzyme found in the alpha-toxin of Clostridium welchii and other strains of clostridia and bacilli. It hydrolyzes glycerophosphatidates with the formation of 1,2-diacylglycerol and a phosphorylated nitrogenous base such as choline.
MSH

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fosfolipasa D

An enzyme found mostly in plant tissue. It hydrolyzes glycerophosphatidates with the formation of a phosphatidic acid and a nitrogenous base such as choline. This enzyme also catalyzes transphosphatidylation reactions. EC 3.1.4.4.
MSH

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fosfolipasy

A class of enzymes that catalyze the hydrolysis of phosphoglycerides or glycerophosphatidates. EC 3.1.-.
MSH

Enzymes that catalyze the cleavage of a phospholipid molecule by the addition of water, thereby causing hydrolysis. The classification is based on the specificity of the bond cleaved. Hydrolytic activity initiates signaling cascades in the cell.
NCI

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fosfolipasy A

Phospholipases that hydrolyze one of the acyl groups of phosphoglycerides or glycerophosphatidates.
MSH

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fosfolipidethery

Phospholipids which have an alcohol moiety in ethereal linkage with a saturated or unsaturated aliphatic alcohol. They are usually derivatives of phosphoglycerols or phosphatidates. The other two alcohol groups of the glycerol backbone are usually in ester linkage. These compounds are widely distributed in animal tissues.
MSH

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fosfolipidy

Lipids containing one or more phosphate groups, particularly those derived from either glycerol (phosphoglycerides see GLYCEROPHOSPHOLIPIDS) or sphingosine (SPHINGOLIPIDS). They are polar lipids that are of great importance for the structure and function of cell membranes and are the most abundant of membrane lipids, although not stored in large amounts in the system.
MSH

any lipid that contains phosphorus, including those with a glycerol backbone or a backbone of sphingosine or related substance; these polar lipids are of great importance for the structure and function of cell membranes and are the most abundant of membrane lipids.
CSP

Phosphate-containing lipids that are a major component of all cell membranes. Most phospholipids contain a diglyceride, a phosphate group, and a simple organic molecule such as choline. Another type of phospholipid is phosphosphingolipids that contain sphingosine instead of glycerol.
NCI

A lipid (fat) that contains phosphorus. Phospholipids are a major part of cell membranes.
NCI

A chemical or drug that is attached to a lipid (fat) that contains phosphorus.
NCI

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fosfomonoesterasy

A group of hydrolases which catalyze the hydrolysis of monophosphoric esters with the production of one mole of orthophosphate. EC 3.1.3.
MSH

a group of hydrolases which catalyze the hydrolysis of monophosphoric esters with the production of one mole of orthophosphate.
CSP

A class of enzymes that catalyze the removal of phosphate groups from their substrates.
NCI

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kyseliny fosfonové

Inorganic or organic derivatives of phosphonic acid with the general formula ROP(OH)2 or RP(=O)(OH)2. The tautomeric form of this compound (P(OH)3) is PHOSPHOROUS ACIDS. Nucleoside phosphonates have a phosphate-carbon bond that is more resistant to enzymatic cleavage than the normal phosphate-oxygen bond.
MSH

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kyselina fosfonoctová

A simple organophosphorus compound that inhibits DNA polymerase, especially in viruses and is used as an antiviral agent.
MSH

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