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Plasmodium vivax

A protozoan parasite that causes vivax malaria (MALARIA, VIVAX). This species is found almost everywhere malaria is endemic and is the only one that has a range extending into the temperate regions.
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Plasmodium yoelii

A species of PLASMODIUM causing malaria in rodents.
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Plaster of Paris

A finely ground mixture of powdered and heat-treated gypsum.
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zvláčňovadla

Materials incorporated mechanically in plastics (usually PVC) to increase flexibility, workability or distensibility; due to the non-chemical inclusion, plasticizers leach out from the plastic and are found in body fluids and the general environment.
MSH

A substance added to plastics or other materials to make or keep them soft or pliable.
NCI

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plastické hmoty

Polymeric materials (usually organic) of large molecular weight which can be shaped by flow. Plastic usually refers to the final product with fillers, plasticizers, pigments, and stabilizers included (versus the resin, the homogeneous polymeric starting material). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
MSH

a high polymer, usually synthetic, defined by its ability to be molded under heat and pressure in its raw state, and the machined or otherwise trimmed in its hardened state.
CSP

Various high-molecular-weight thermoplastic or thermosetting polymers that are capable of being molded, extruded, drawn, or otherwise shaped and then hardened into a form. It is solid in its finished state.
NCI

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plastokyanin

A copper-containing plant protein that is a fundamental link in the electron transport chain of green plants during the photosynthetic conversion of light energy by photophosphorylation into the potential energy of chemical bonds.
MSH

plant copper protein; involved in photosynthesis.
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plastochinon

Polyunsaturated side-chain quinone derivative which is an important link in the electron transport chain of green plants during the photosynthetic conversion of light energy by photophosphorylation into the potential energy of chemical bonds.
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faktor aktivující trombocyty

A phospholipid derivative formed by PLATELETS; BASOPHILS; NEUTROPHILS; MONOCYTES; and MACROPHAGES. It is a potent platelet aggregating agent and inducer of systemic anaphylactic symptoms, including HYPOTENSION; THROMBOCYTOPENIA; NEUTROPENIA; and BRONCHOCONSTRICTION.
MSH

produced in response to specific stimuli by a variety of cell types, including neutrophils, basophils, platelets, and endothelial cells; several molecular species of platelet activating factor have been identified which vary in the length of the O-alkyl side chain; an important mediator of bronchoconstriction.
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trombocyty – aktivace

A series of progressive, overlapping events, triggered by exposure of the PLATELETS to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.
MSH

process by which platelets change shape, aggregate, adhere to vascular wall, and secrete cytokines during clotting; induced by a variety of agonists including thrombin, ADP, PAF, and epinephrine via a G protein/IP3 coupled receptor system.
CSP

A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug. [http://www.graylab.ac.uk/omd/]
GO

Platelet Activation involves initiation of a set of stimulated platelet activities involved in aggregation of platelets and fibrin during blood coagulation.
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trombocyty – adhezivita

The process whereby PLATELETS adhere to something other than platelets, e.g., COLLAGEN; BASEMENT MEMBRANE; MICROFIBRILS; or other “foreign” surfaces.
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trombocyty – agregace

The attachment of PLATELETS to one another. This clumping together can be induced by a number of agents (e.g., THROMBIN; COLLAGEN) and is part of the mechanism leading to the formation of a THROMBUS.
MSH

attachment of platelets to one another; part of the mechanism leading to the formation of a thrombus.
CSP

The adhesion of one platelet to one or more other platelets via adhesion molecules. [GOC:BHF, GOC:vk]
GO

Any cell adhesion process that involves the association of platelets via adhesion molecules.
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inhibitory agregace trombocytů

drugs or agents which antagonize or impair any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
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trombocyty – počet

The number of PLATELETS per unit volume in a sample of venous BLOOD.
MSH

The determination of the number of platelets in a blood sample, usually expressed as platelets per cubic millimeter (cmm) of whole blood.
NCI

A measurement of the platelets in a biological specimen.
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trombocytový faktor 3

A phospholipid from the platelet membrane that contributes to the blood clotting cascade by forming a phospholipid-protein complex (THROMBOPLASTIN) which serves as a cofactor with FACTOR VIIA to activate FACTOR X in the extrinsic pathway of BLOOD COAGULATION.
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trombocytový faktor 4

A CXC chemokine that is found in the alpha granules of PLATELETS. The protein has a molecular size of 7800 kDa and can occur as a monomer, a dimer or a tetramer depending upon its concentration in solution. Platelet factor 4 has a high affinity for HEPARIN and is often found complexed with GLYCOPROTEINS such as PROTEIN C.
MSH

high molecular weight proteoglycan-platelet factor complex which is released from blood platelets by thrombin; acts as a mediator in the heparin-neutralizing capacity of the blood and plays a role in platelet aggregation.
CSP

Platelet factor-4 is a 70-amino acid CXC chemokine. It is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair. (from OMIM)
NCI

A recombinant form of the endogenous chemokine platelet factor 4 with potential antiangiogenesis and antineoplastic activities. As a heparin-binding tetramer, recombinant platelet factor 4 inhibits growth factor-stimulated endothelial cell proliferation, migration, and angiogenesis; it has been shown that this agent inhibits fibroblast growth factor 2 (FGF2) angiogenic activity downstream from the FGF2 receptor. Its activity is antagonized by heparin. Recombinant platelet factor 4 may also directly inhibit the proliferation of some tumor cell types.
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trombocytový membránový glykoprotein IIb

Platelet membrane glycoprotein IIb is an integrin alpha subunit that heterodimerizes with INTEGRIN BETA3 to form PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX. It is synthesized as a single polypeptide chain which is then postranslationally cleaved and processed into two disulfide-linked subunits of approximately 18 and 110 kDa in size.
MSH

Integrin alpha-IIb (1039 aa, ~113 kDa) is encoded by the human ITGA2B gene. This protein is involved in the mediation of platelet clotting.
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glykoproteiny membrány trombocytů

Surface glycoproteins on platelets which have a key role in hemostasis and thrombosis such as platelet adhesion and aggregation. Many of these are receptors.
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trombocyty – deficit ukládacího poolu

Disorder characterized by a decrease or lack of platelet dense bodies in which the releasable pool of adenine nucleotides and 5HT are normally stored.
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růstový faktor odvozený z trombocytů

Mitogenic peptide growth hormone carried in the alpha-granules of platelets. It is released when platelets adhere to traumatized tissues. Connective tissue cells near the traumatized region respond by initiating the process of replication.
MSH

mitogenic peptide growth hormone carried in the alpha-granules of platelets; released when platelets adhere to traumatized tissues; connective tissue cells near the traumatized region respond by initiating the process of replication.
CSP

A family of molecules released from platelets (tiny pieces of cells that are found in the blood and that help the blood clot). Forms of PDGF help to heal wounds and to repair damage to blood vessel walls. They also help blood vessels grow.
NCI

Expressed in platelets, human Platelet-Derived Growth Factor (PDGF/VEGF Family) is a mitogenic factor for mesenchymal cells characterized by a motif of eight cysteines and released upon wounding to stimulate adjacent cell growth. PDGF can exist as antiparallel disulfide-linked homodimers (PDGFA, PDGFB) or heterodimers (PDGFA/PDGFB) that bind to PDGF receptor and elicit a variety of cellular responses. A and B homodimers are implicated in transformation processes. (NCI)
NCI

The major mitogen in serum for growth in culture of cells of connective tissue origin. It consists of 2 different but homologous polypeptides A and B (~30,000 D) linked by disulphide bonds. The B chain is almost identical in sequence to p28sis, the transforming protein of simian sarcoma virus.
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trombocytoferéza

The preparation of platelet concentrates with the return of red cells and platelet-poor plasma to the donor.
MSH

preparation of platelet concentrates with the return of red cells and platelet-poor plasma to the donor.
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Platichtys

Genus of Pleuronectidae comprising European flounder.
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platina

Platinum. A heavy, soft, whitish metal, resembling tin, atomic number 78, atomic weight 195.09, symbol Pt. (From Dorland, 28th ed) It is used in manufacturing equipment for laboratory and industrial use. It occurs as a black powder (platinum black) and as a spongy substance (spongy platinum) and may have been known in Pliny`s time as “alutiae”.
MSH

heavy whitish metal, symbol Pt, atomic number 78; metallic platinum is insoluble except in nitrohydrochloric acid and fusible only at very high temperatures, and therefore used in the manufacture of equipment for laboratory and industrial use; platinum black and spongy platinum act as powerful oxidizing and catalytic agents.
CSP

A metal that is an important component of some anticancer drugs, such as cisplatin and carboplatin.
NCI

An element with atomic symbol Pt, atomic number 78, and atomic weight 195.09.
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platybazie

A developmental deformity of the occipital bone and upper end of the cervical spine, in which the latter appears to have pushed the floor of the occipital bone upward. (Dorland, 27th ed)
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Plathelminthes

A phylum of acoelomate, bilaterally symmetrical flatworms, without a definite anus. It includes three classes: Cestoda, Turbellaria, and Trematoda.
MSH

phylum of acoelomate, bilaterally symmetrical flatworms, without a definite anus; includes three classes, Cestoda, Turbellaria, and Trematoda.
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Platypus

A small aquatic oviparous mammal of the order Monotremata found in Australia and Tasmania.
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hra a hračky

Spontaneous or voluntary recreational activities pursued for enjoyment and accessories or equipment used in the activities; includes games, toys, etc.
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terapie hrou

A treatment technique utilizing play as a medium for expression and communication between patient and therapist.
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princip potěšení-bolest

The psychoanalytic concept that man instinctively seeks to avoid pain and discomfort and strives for gratification and pleasure.
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Pleomorphism

Having different forms at different stages of the life cycle.
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pletysmografie

Recording of change in the size of a part as modified by the circulation in it.
MSH

recording the changes in the size of a part as modified by the circulation of the blood in it.
CSP

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