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polyurie

Urination of a large volume of urine with an increase in urinary frequency, commonly seen in diabetes (DIABETES MELLITUS; DIABETES INSIPIDUS).
MSH

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polyvinylalkohol

A polymer prepared from polyvinyl acetates by replacement of the acetate groups with hydroxyl groups. It is used as a pharmaceutic aid and ophthalmic lubricant as well as in the manufacture of surface coatings artificial sponges, cosmetics, and other products.
MSH

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polyvinylchlorid

A polyvinyl resin used extensively in the manufacture of plastics, including medical devices, tubing, and other packaging. It is also used as a rubber substitute.
MSH

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polyvinylpyridin-N-oxid

Inhibits the cytotoxic action of quartz and is reported to have delayed the development of experimental silicosis in rats.
MSH

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polyvinyly

polymerization product of a monomeric vinyl compound.
CSP

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Pomeroy Method

A knuckle of FALLOPIAN TUBE is ligated with absorbable suture, then a small segment is excised.
MSH

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ekzém dyshidrotický

A recurrent eczematous reaction characterized by the development of vesicular eruptions on the palms and soles, particularly along the sides and between the digits. It is accompanied by pruritus, a burning sensation, and hyperhidrosis. The disease is self-limiting, lasting only a few weeks. (Dorland, 27th ed)
MSH

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Apen

anthropoid apes, a family of primates that includes gorillas, orangutans, and chimpanzees; some are used in laboratory experiments because of their relationship to humans.
CSP

An obsolete name for a family of Primates consisting of three genera: Pongo (PONGO PYGMAEUS), Pan (PAN TROGLODYTES and PAN PANISCUS), and Gorilla (GORILLA GORILLA).
MSH

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Pongo pygmaeus

A species of orangutan, family HOMINIDAE, found in the forests on the island of Borneo.
MSH

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pons

The front part of hindbrain that lies between MEDULLA OBLONGATA and the midbrain (MESENCEPHALON) ventral to the CEREBELLUM. It is composed of two parts, the dorsal and the ventral. Pons serves as a relay station for important neural pathways between the cerebellum to the CEREBRUM.
MSH

part of the central nervous system lying between the medulla oblongata and the mesencephalon, ventral to the cerebellum, and consisting of a pars dorsalis and a pars ventralis.
CSP

Part of the central nervous system, located at the base of the brain, between the medulla oblongata and the midbrain. It is part of the brainstem.
NCI

Having to do with the pons (part of the central nervous system, located at the base of the brain, between the medulla oblongata and the midbrain).
NCI

Organ component of neuraxis that has as its parts the pontine tegmentum and basal part of pons. Examples: There is only one pons.
FMA

a part of the brain structure
CHV

The middle portion of the brainstem located between the midbrain and the medulla oblongata. The fourth ventricle lies dorsal to the pons which also contains the motor trigeminal nuclei and the abducens nuclei. The cerebellum contributes a large number of afferent fibers to the pons.
NCI

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arteria poplitea

The continuation of the femoral artery coursing through the popliteal fossa; it divides into the anterior and posterior tibial arteries.
MSH

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popliteální cysta

A SYNOVIAL CYST located in the back of the knee, in the popliteal space arising from the semimembranous bursa or the knee joint.
MSH

a benign swelling found behind the knee joint
CHV

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vena poplitea

The vein formed by the union of the anterior and posterior tibial veins; it courses through the popliteal space and becomes the femoral vein.
MSH

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populace

The total number of individuals inhabiting a particular region or area.
MSH

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populační charakteristiky

Qualities and characterization of various types of populations within a social or geographic group, with emphasis on demography, health status, and socioeconomic factors.
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populace – kontrola růstu

Includes mechanisms or programs which control the numbers of individuals in a population of humans or animals.
MSH

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populace – hustota

Number of individuals in a population relative to space.
MSH

number of human individuals in a population relative to space.
CSP

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populační dynamika

The pattern of any process, or the interrelationship of phenomena, which affects growth or change within a population.
MSH

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populace – růst

Increase, over a specific period of time, in the number of individuals living in a country or region.
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populace – surveillance

Ongoing scrutiny of a population (general population, study population, target population, etc.), generally using methods distinguished by their practicability, uniformity, and frequently their rapidity, rather than by complete accuracy.
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dikobrazovití a urzonovití

Common name for large, quilled rodents (RODENTIA) comprised of two families: Old World porcupines (Hystricidae) and New World porcupines (Erethizontidae).
MSH

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porfiromycin

Toxic antibiotic of the mitomycin group, obtained from MITOMYCIN and also from Streptomyces ardus and other species. It is proposed as an antineoplastic agent, with some antibiotic properties.
MSH

A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called anticancer antibiotics.
NCI

An N-methyl derivative of the antineoplastic antibiotic mitomycin C isolated from the bacterium Streptomyces ardus and other Streptomyces bacterial species. Bioreduced porfiromycin generates oxygen radicals and alkylates DNA, producing interstrand cross-links and single-strand breaks, thereby inhibiting DNA synthesis. Porfiromycin is preferentially toxic to hypoxic cells. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39610&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39610&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C763″ NCI Thesaurus)
PDQ

An N-methyl derivative of the antineoplastic antibiotic mitomycin C isolated from the bacterium Streptomyces ardus and other Streptomyces bacterial species. Bioreduced porfiromycin generates oxygen radicals and alkylates DNA, producing interstrand cross-links and single-strand breaks, thereby inhibiting DNA synthesis. Porfiromycin is preferentially toxic to hypoxic cells. (NCI04)
NCI

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Porifera

phylum of sponges, the most primitive of multicellular animals; perforated with many pores to admit water, through which food is strained; all sponges are sessile and exhibit little detectable movement; most are hermaphroditic; organisms are a source of alkaloids, sterols and other natural products useful in medicine and biological research.
CSP

The phylum of sponges which are sessile, suspension-feeding, multicellular animals that utilize flagellated cells called choanocytes to circulate water. Most are hermaphroditic. They are probably an early evolutionary side branch that gave rise to no other group of animals. Except for about 150 freshwater species, sponges are marine animals. They are a source of ALKALOIDS; STEROLS; and other complex molecules useful in medicine and biological research.
MSH

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porfobilinogen

immediate precursor of the porphyrins, a pyrrole ring with acetyl, propionyl, and aminomethyl side chains; produced in excess and excreted in the urine in porphyrias.
CSP

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hydroxymethylbilansynthasa

An enzyme that catalyzes the tetrapolymerization of the monopyrrole PORPHOBILINOGEN into the hydroxymethylbilane preuroporphyrinogen (UROPORPHYRINOGENS) in several discrete steps. It is the third enzyme in the 8-enzyme biosynthetic pathway of HEME. In humans, deficiency in this enzyme encoded by HMBS (or PBGD) gene results in a form of neurological porphyria (PORPHYRIA, ACUTE INTERMITTENT). This enzyme was formerly listed as EC 4.3.1.8
MSH

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porfyrie

group of disorders characterized by the excessive production of porphyrins or their precursors that arises from abnormalities in the regulation of the porphyrin-heme pathway; acquired porphyrias, which are due to inhibition of enzymes in the metabolic pathway by a drug, toxin or abnormal metabolite, are more common than those which are inherited.
CSP

Porphyrias are a group of genetic disorders caused by problems with how your body makes a substance called heme. Heme is found throughout the body, especially in your blood and bone marrow, where it carries oxygen.

Porphyrias affect the skin or the nervous system. People with the skin type develop blisters, itching, and swelling of their skin when it is exposed to sunlight. The nervous system type is called acute porphyria. Symptoms include pain in the chest or abdomen, vomiting, and diarrhea or constipation. During an attack, symptoms can include muscle numbness, tingling, paralysis, cramping, and personality or mental changes. Certain triggers can cause an attack, including some medicines, smoking, drinking alcohol, infections, stress and sun exposure. Attacks develop over hours or days. They can last for days or weeks.

Porphyria can be hard to diagnose. It requires blood, urine and stool tests. Each type has a different treatment. It usually involves medicine, treatment with heme or drawing blood.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases


MEDLINEPLUS

a disease characterized by the presence of large amounts of porphyrins in the blood and urine
CHV

A diverse group of metabolic diseases characterized by errors in the biosynthetic pathway of HEME in the LIVER, the BONE MARROW, or both. They are classified by the deficiency of specific enzymes, the tissue site of enzyme defect, or the clinical features that include neurological (acute) or cutaneous (skin lesions). Porphyrias can be hereditary or acquired as a result of toxicity to the hepatic or erythropoietic marrow tissues.
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porfyrinogeny

Colorless reduced precursors of porphyrins in which the pyrrole rings are linked by methylene (-CH2-) bridges.
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porfyriny

A group of compounds containing the porphin structure, four pyrrole rings connected by methine bridges in a cyclic configuration to which a variety of side chains are attached. The nature of the side chain is indicated by a prefix, as uroporphyrin, hematoporphyrin, etc. The porphyrins, in combination with iron, form the heme component in biologically significant compounds such as hemoglobin and myoglobin.
MSH

group of compounds containing the porphin structure, four pyrrole rings connected by methine bridges in a cyclic configuration to which a variety of side chains are attached; the nature of the side chain is indicated by a prefix, as uroporphyrin, hematoporphyrin, etc; the porphyrins, in combination with iron, form the heme component in biologically significant compounds such as hemoglobin and myoglobin.
CSP

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sviňuchy

Mammals of the family Phocoenidae comprising four genera found in the North Pacific Ocean and both sides of the North Atlantic Ocean and in various other seas. They differ from DOLPHINS in that porpoises have a blunt snout and a rather stocky body while dolphins have a beak-like snout and a slender, streamlined body. They usually travel in small groups. (From Walker`s Mammals of the World, 5th ed, pp1003-4)
MSH

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portokavální zkrat chirurgický

Surgical portasystemic shunt between the portal vein and inferior vena cava.
MSH

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