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promegeston

A synthetic progestin which is useful for the study of progestin distribution and progestin tissue receptors, as it is not bound by transcortin and binds to progesterone receptors with a higher association constant than progesterone.
MSH

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promethazin

A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals.
MSH

a drug used to treat allergy symptoms
CHV

A phenothiazine derivative with antiemetic and antihistaminic properties. Promethazine antagonizes the central and peripheral effects of histamine mediated by histamine H1 receptors. The effects include bronchoconstriction, vasodilation and spasmodic contractions of gastrointestinal smooth muscle. In addition, this agent binds to muscarinic receptors, resulting in anticholinergic and antiemetic activities.
NCI

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promethium

Promethium. A radioactive element of the rare earth family of metals. It has the atomic symbol Pm, atomic number 61, and atomic weight 147. It has been used in the construction of atomic batteries, in the preparation of self-luminous compounds, and as a beta-particle source for thickness gauges.
MSH

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prometryn

A triazine used as a selective pre- and post-emergence herbicide. (From Merck Index, 11th ed)
MSH

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promotorové oblasti (genetika)

DNA sequences which are recognized and bound by a DNA-dependent RNA polymerase during the initiation of transcription; highly conserved sequences within the promoter include the TATA BOX in eukaryotes.
CSP

DNA sequences which are recognized (directly or indirectly) and bound by a DNA-dependent RNA polymerase during the initiation of transcription. Highly conserved sequences within the promoter include the Pribnow box in bacteria and the TATA BOX in eukaryotes.
MSH

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Povýšení

Encouragement of the progress or growth or acceptance of something.
NCI

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promyelocyty

A cell of the bone marrow that is derived from myeloblasts and will give rise to myelocytes, precursors of myeloid cells and neutrophil granulocytes.
NCI

The cells in the granulocytic series that are derived from myeloblasts and that are the earliest cells of the myelocyte stage.
MSH

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pronasa

A proteolytic enzyme obtained from Streptomyces griseus.
MSH

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pronace

Applies to movements of the forearm in turning the palm backward or downward. When referring to the foot, a combination of eversion and abduction movements in the tarsal and metatarsal joints (turning the foot up and in toward the midline of the body).
MSH

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pronační poloha

The posture of an individual lying face down.
MSH

An anterior recumbent body position whereby the person lies on its stomach and faces downward.
NCI

An anterior recumbent body position whereby the person lies on its stomach and faces downward. (NCI)
NCI

Lying with the front or ventral surface downward; lying face down.

Deprecation Comment:This concept has been deprecated because it does not describe a type of Act (as it should in the ActClass code system), but rather encodes the result or value of an observation. The same code has been added to the ObservationValue code system.


HL7V3.0

Lying with the front or ventral surface downward; lying face down.


HL7V3.0

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propafenon

An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity. The drug is generally well tolerated.
MSH

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propaganda

The deliberate attempt to influence attitudes and beliefs for furthering one`s cause or damaging an opponent`s cause.
MSH

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propan

hydrocarbon of the methane series, CH3-CH2-CH3, which is a constituent of natural gas and crude petroleum and occurs as a colorless flammable gas with a characteristic odor.
CSP

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propandioldehydratasa

An enzyme that catalyzes the dehydration of 1,2-propanediol to propionaldehyde. EC 4.2.1.28.
MSH

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propylenglykoly

Derivatives of propylene glycol (1,2-propanediol). They are used as humectants and solvents in pharmaceutical preparations.
MSH

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propanidid

An intravenous anesthetic that has been used for rapid induction of anesthesia and for maintenance of anesthesia of short duration. (From Martindale, The Extra Pharmacopoeia, 30th ed, p918)
MSH

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propanil

A chlorinated anilide that is used as an herbicide.
MSH

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propanolaminy

AMINO ALCOHOLS containing the propanolamine (NH2CH2CHOHCH2) group and its derivatives.
MSH

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propanthelin

A muscarinic antagonist used as an antispasmodic, in rhinitis, in urinary incontinence, and in the treatment of ulcers. At high doses it has nicotinic effects resulting in neuromuscular blocking.
MSH

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Propantheline Bromide

The bromide salt form of propantheline, a quaternary ammonium compound structurally related to belladonna alkaloids. Propantheline bromide competitively antagonizes acetylcholine activity mediated by muscarinic receptors at neuroeffector sites on smooth muscle and exocrine gland cells. An aspartic acid residue present in the N-terminal portion of the third trans-membrane helix of the muscarinic receptor is believed to form an ionic bond with the tertiary or quaternary nitrogen of the antagonist. Antagonism leads to a reduction of exocrine glands secretions and to relax bronchial muscle and reduce tone and motility of intestinal smooth muscle.
NCI

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properdin

A 53-kDa protein that is a positive regulator of the alternate pathway of complement activation (COMPLEMENT ACTIVATION PATHWAY, ALTERNATIVE). It stabilizes the ALTERNATIVE PATHWAY C3 CONVERTASE (C3bBb) and protects it from rapid inactivation, thus facilitating the cascade of COMPLEMENT ACTIVATION and the formation of MEMBRANE ATTACK COMPLEX. Individuals with mutation in the PFC gene exhibit properdin deficiency and have a high susceptibility to infections.
MSH

a non-immunoglobulin, gammaglobulin complement of the alternative pathway; it complexes with C3b and stabilizes alternative pathway C3 convertase.
CSP

blood protein
CHV

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komplement – faktor B

A glycine-rich, heat-labile serum glycoprotein that contains a component of the C3 CONVERTASE ALTERNATE PATHWAY (C3bBb). Bb, a serine protease, is generated when factor B is cleaved by COMPLEMENT FACTOR D into Ba and Bb.
MSH

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komplement – faktor D

A serum protein which is important in the ALTERNATIVE COMPLEMENT ACTIVATION PATHWAY. This enzyme cleaves the COMPLEMENT C3B-bound COMPLEMENT FACTOR B to form C3bBb which is ALTERNATIVE PATHWAY C3 CONVERTASE.
MSH

Complement factor D (253 aa, ~27 kDa) is encoded by the human CFD gene. This protein plays a role in the activation of the alternate complement pathway.
NCI

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Prophage Excision

The molecular events that lead to the excision of a viral genome from the host genome. [GOC:mlg]
GO

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profáze

The first phase of cell nucleus division, in which the CHROMOSOMES become visible, the CELL NUCLEUS starts to lose its identity, the MITOTIC SPINDLE APPARATUS appears, and the CENTRIOLES migrate toward opposite poles.
MSH

A cell cycle process comprising the steps by which a cell progresses through prophase, the first stage of chromosome segregation in the cell cycle. Canonically, chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell. [GOC:ai, GOC:dph, GOC:mah]
GO

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propidium

Quaternary ammonium analog of ethidium; an intercalating dye with a specific affinity to certain forms of DNA and, used as diiodide, to separate them in density gradients; also forms fluorescent complexes with cholinesterase which it inhibits.
MSH

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Propidium Iodide

A fluorescent nucleic acid dye which binds only to double-stranded nucleic acids. It has a molecular weight of 668.4, an absorbance maximum of 535nm, and an emission maximum of 617 nm. It is commonly used to determine the DNA content of a cell or to discriminate viable from non-viable cells.
NCI

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propiolakton

Disinfectant used in vapor form to sterilize vaccines, grafts, etc. The vapor is very irritating and the liquid form is carcinogenic.
MSH

A colorless, highly reactive, liquid, cyclic ether with a slightly sweet odor. Beta-propiolactone was used once mainly in the manufacture of acrylic acid and esters. It also was used as a sterilant for medical materials and procedures. However, it is no longer used for medical disinfection. Dermal exposure to beta-propiolactone causes the burning or blistering of the skin, and ingestion of this substance burns the mouth and stomach while exposure to its vapors causes severe irritation of the eyes, throat and respiratory tract. This substance is reasonably anticipated to be a human carcinogen. (NCI05)
NCI

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propiomazine

A phenothiazine derivative and atypical antipsychotic agent with sedative, antiemetic and antipsychotic activities. Propiomazine binds to a variety of receptors, including alpha1, dopamine, histamine H1, muscarinic, and serotonin type 2 (5-HT2) receptors. Propiomazine exerts its antiemetic and sedative effects through antagonism at histamine H1 receptors; Its antipsychotic effect is attributed to antagonistic activities at dopamine and 5-HT2 receptors.
NCI

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propionáty

three carbon saturated fatty acid that can be fermented by several species of bacteria; in mammals it can be converted to the thioester propionyl CoA, a metabolic intermediate.
CSP

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