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Actinomyces israelii (bacteria)

A species of anaerobic, Gram positive, rod shaped bacteria assigned to the phylum Actinobacteria. This bacteria hydrolyzes esculin, produces acid from xylose and is urease and catalase negative. A. israelii is found in the flora of the human oral and nasopharyngeal tract and in animals and is the most frequent cause of actinomycosis in humans.
NCI

Any bacterial organism that can be assigned to the species Actinomyces israelii.
NCI

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Actinomycetaceae

A family of bacteria including numerous parasitic and pathogenic forms.
MSH

A taxonomic family of filamentous or rod shaped bacterium in the phylum Actinobacteria with type genus actinomyces.
NCI

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Actinomycetales

order of gram positive, primarily aerobic bacteria that tend to form branching filaments.
CSP

An order of gram-positive, primarily aerobic BACTERIA that tend to form branching filaments.
MSH

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Actinomycetales – infekce

Infections with bacteria of the order ACTINOMYCETALES.
MSH

gram positive bacterial infection by organism of the order Actinomycetales.
CSP

An infectious process caused by actinomycetales which is an order of Actinobacteria.
NCI

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Actinomycin

group of peptide antibiotic agents, isolated from several species of Streptomyces (originally Actinomyces), that are active against gram positive bacteria, fungi, and neoplasms; they form complexes with DNA and therefore inhibit RNA synthesis, primarily the ribosomal type.
CSP

A chromopeptide antineoplastic antibiotic isolated from the bacterial genus Streptomyces. Actinomycin antibiotics inhibit DNA replication and RNA and protein synthesis by various mechanisms such as intercalating into the minor groove of DNA and interfering with the function of topoisomerase II.
NCI

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aktinomykóza

Infections with bacteria of the genus ACTINOMYCES.
MSH

An infectious process caused by bacteria of the Actinomyces species. It is characterized by the formation of purulent and painful abscesses in the mouth, lungs and gastrointestinal tract.
NCI

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aktinomykóza cervikofaciální

A form of ACTINOMYCOSIS characterized by slow-growing inflammatory lesions of the lymph nodes that drain the mouth (lumpy jaw), reddening of the overlying skin, and intraperitoneal abscesses.
MSH

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spektinomycin

An antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of gonorrhea.
MSH

An aminocyclitol aminoglycoside antibiotic derived from Streptomyces spectabilis with bacteriostatic activity. Spectinomycin binds to the bacterial 30S ribosomal subunit. As a result, this agent interferes with the initiation of protein synthesis and with proper protein elongation. This eventually leads to bacterial cell death.
NCI

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aktiny

Filamentous proteins that are the main constituent of the thin filaments of muscle fibers. The filaments (known also as filamentous or F-actin) can be dissociated into their globular subunits; each subunit is composed of a single polypeptide 375 amino acids long. This is known as globular or G-actin. In conjunction with MYOSINS, actin is responsible for the contraction and relaxation of muscle.
MSH

globular subunit of microfilaments, whose ATP-dependent polymerization and movement underlies many dynamic cellular phenomena in addition to muscle contraction; actin is one of the most abundant proteins in eukaryotic cells.
CSP

A globular subunit of microfilaments, highly conserved Actin is one of the most abundant proteins in eukaryotic cells. Monomeric actin, a slow ATPase composed of a 375 amino acid polypeptide chain, interacts with one molecule of ATP or ADP and contains high affinity and low affinity binding sites for divalent cations. Actin can quickly assemble into long microfilament polymers. In conjunction with myosin, actin is responsible for the contraction and relaxation of muscle.
NCI

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akční potenciály

Abrupt changes in the membrane potential that sweep along the CELL MEMBRANE of excitable cells in response to excitation stimuli.
MSH

a rapid self-propagating change in the electrical potential across a neuron, gland, or muscle fiber membrane primarily due to a sudden influx of sodium ions followed by an efflux of potassium ions.
CSP

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aktivační analýza

A method of chemical analysis based on the detection of characteristic radionuclides following a nuclear bombardment. It is also known as radioactivity analysis. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
MSH

chemical analytic method based on the detection of characteristic radionuclides following a nuclear bombardment.
CSP

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aktivátorové přístroje

Loose-fitting removable orthodontic appliances which redirect the pressures of the facial and masticatory muscles onto the teeth and their supporting structures to produce improvements in tooth arrangements and occlusal relations.
MSH

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eutanazie aktivní

The act or practice of killing for reasons of mercy, i.e., in order to release a person or animal from incurable disease, intolerable suffering, or undignified death. (from Beauchamp and Walters, Contemporary Issues in Bioethics, 5th ed)
MSH

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činnosti denního života

The performance of the basic activities of self care, such as dressing, ambulation, or eating.
MSH

physical, mental, or social ability to carry on the normal activities of life.
CSP

Those physical activities which are required for our daily existence. These include personal maintenance activities such as dressing and bathing and activities for maintenance of our living space such as cleaning.
NCI

The tasks of everyday life. These activities include eating, dressing, getting into or out of a bed or chair, taking a bath or shower, and using the toilet. Instrumental activities of daily living are activities related to independent living and include preparing meals, managing money, shopping, doing housework, and using a telephone.
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aktivita – cykly

Bouts of physical irritability or movement alternating with periods of quiescence. It includes biochemical activity and hormonal activity which may be cellular. These cycles are shorter than 24 hours and include sleep-wakefulness cycles and the periodic activation of the digestive system.
MSH

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aktomyosin

A protein complex of actin and MYOSINS occurring in muscle. It is the essential contractile substance of muscle.
MSH

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pojišťovací analýza

The application of probability and statistical methods to calculate the risk of occurrence of any event, such as onset of illness, recurrent disease, hospitalization, disability, or death. It may include calculation of the anticipated money costs of such events and of the premiums necessary to provide for payment of such costs.
MSH

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akupunktura

The occupational discipline of the traditional Chinese methods of ACUPUNCTURE THERAPY for treating disease by inserting needles along specific pathways or meridians.
MSH

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akupunkturní analgézie

Analgesia produced by the insertion of ACUPUNCTURE needles at certain ACUPUNCTURE POINTS on the body. This activates small myelinated nerve fibers in the muscle which transmit impulses to the spinal cord and then activate three centers – the spinal cord, midbrain and pituitary/hypothalamus – to produce analgesia.
MSH

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Acupuncture Anesthesia

Use of ACUPUNCTURE to block the afferent nerve impulses from reaching the brain to reduce the sensation of pain for surgery.
MSH

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akupunkturní body

Designated locations along nerves or organ meridians for inserting acupuncture needles.
MSH

A specific spot on the body where an acupuncture needle may be inserted to control pain and other symptoms.
NCI

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akutní nemoc

Disease having a short and relatively severe course.
MSH

disease or disorder which has a short and relatively severe course; post coordinate with specific disease or disorder if appropriate.
CSP

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Akutní pankreatitida

An acute inflammatory process that leads to necrosis of the pancreatic parenchyma. Signs and symptoms include severe abdominal pain, nausea, vomiting, diarrhea, fever, and shock. Causes include alcohol consumption, presence of gallstones, trauma, and drugs.
NCI

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proteiny akutní fáze

blood proteins that are produced in response to acute illness; including fibrinogen, ceruloplasmin, certain enzyme inhibitors and C reactive protein.
CSP

Proteins that are secreted into the blood in increased or decreased quantities by hepatocytes in response to trauma, inflammation, or disease. These proteins can serve as inhibitors or mediators of the inflammatory processes. Certain acute-phase proteins have been used to diagnose and follow the course of diseases or as tumor markers.
MSH

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reakce akutní fáze

An early local inflammatory reaction to insult or injury that consists of fever, an increase in inflammatory humoral factors, and an increased synthesis by hepatocytes of a number of proteins or glycoproteins usually found in the plasma.
MSH

An acute inflammatory response that involves non-antibody proteins whose concentrations in the plasma increase in response to infection or injury of homeothermic animals. [ISBN:0198506732 “Oxford Dictionary of Biochemistry and Molecular Biology”]
GO

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masivní nekróza jater

Extensive and rapid death of parenchymal cells in the LIVER, often due to exposure to toxic materials. It is characterized by a soft, flabby, yellow-brown wrinkled, and shrunken liver. It was called “acute yellow atrophy”.
MSH

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acyklovir

A GUANOSINE analog that acts as an antimetabolite. Viruses are especially susceptible. Used especially against herpes.
MSH

9-(2-hydroxyethoxymethyl) guanine; acts against herpesviruses by inhibiting the viral DNA polymerase.
CSP

A substance used to prevent or treat cytomegalovirus and herpes simplex infections that may occur when the body is immunosuppressed. It belongs to the family of drugs called antivirals.
NCI

a drug used to treat initial genital herpes infections
CHV

A synthetic analog of the purine nucleoside, guanosine, with potent antiviral activity against herpes simplex viruses type 1 and 2, varicella-zoster virus and other viruses. After conversion in vivo to the active metabolite acyclovir triphosphate, acyclovir competitively inhibits viral DNA polymerase, incorporates into and terminates the growing viral DNA chain, and inactivates viral DNA polymerase. The greater antiviral activity of acyclovir against HSV compared to VZV is due to its more efficient phosphorylation by the thymidine kinase of HSV. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39134&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39134&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C205″ NCI Thesaurus)
PDQ

A synthetic analog of the purine nucleoside, guanosine, with potent antiviral activity against herpes simplex viruses type 1 and 2, varicella-zoster virus and other viruses. After conversion in vivo to the active metabolite acyclovir triphosphate, acyclovir competitively inhibits viral DNA polymerase, incorporates into and terminates the growing viral DNA chain, and inactivates viral DNA polymerase. The greater antiviral activity of acyclovir against HSV compared to VZV is due to its more efficient phosphorylation by the thymidine kinase of HSV. (NCI04)
NCI

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protein přenášející acyl

Consists of a polypeptide chain and 4`-phosphopantetheine linked to a serine residue by a phosphodiester bond. Acyl groups are bound as thiol esters to the pantothenyl group. Acyl carrier protein is involved in every step of fatty acid synthesis by the cytoplasmic system.
MSH

small subunits of mitochondrial fatty acid synthase complex that covalently bind the growing fatty acid and carry it through the course of synthesis.
CSP

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acylkoenzym A

S-Acyl coenzyme A. Fatty acid coenzyme A derivatives that are involved in the biosynthesis and oxidation of fatty acids as well as in ceramide formation.
MSH

S-acyl coenzyme A; fatty acid coenzyme A derivatives that are involved in the biosynthesis and oxidation of fatty acids as well as in ceramide formation.
CSP

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acylace

The addition of an organic acid radical into a molecule.
MSH

introduction of an acyl radical into a chemical compound.
CSP

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