Additional pages

Americká asociace pro veřejné zdravotnictví

Professional organization concerned with issues affecting personal and environmental health, including federal and state funding for health programs, programs related to chronic and infectious diseases, and professional education in public health.
MSH

The oldest and largest organization of public health professionals in the world, representing more than 50,000 members from more than 50 occupations of public health. APHA brings together researchers, health service providers, administrators, teachers, and other health workers, forming multi-disciplinary environment for professional exchange, study, and action. Publishes the American Journal of Public Health.
NCI

Price: $1.00

Loading Updating cart…

americium

Americium. A completely man-made radioactive actinide with atomic symbol Am, atomic number 95, and atomic weight 243. Its valence can range from +3 to +6. Because of its nonmagnetic ground state, it is an excellent superconductor. It is also used in bone mineral analysis and as a radiation source for radiotherapy.
MSH

completely man-made radioactive actinide with atomic symbol Am; because of its nonmagnetic ground state, it is an excellent superconductor; it is also used in bone mineral analysis and as a radiation source for radiotherapy.
CSP

A man-made radioactive element with atomic symbol Am, atomic number 95, and atomic weight 243.
NCI

Price: $1.00

Loading Updating cart…

mitomycin

An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
MSH

antineoplastic antibiotic produced by Streptomyces caespitosus that acts as an alkylating agent causing cross-linking of DNA and inhibition of DNA synthesis.
CSP

A methylazirinopyrroloindoledione antineoplastic antibiotic isolated from the bacterium Streptomyces caespitosus and other Streptomyces bacterial species. Bioreduced mitomycin C generates oxygen radicals, alkylates DNA, and produces interstrand DNA cross-links, thereby inhibiting DNA synthesis. Preferentially toxic to hypoxic cells, mitomycin C also inhibits RNA and protein synthesis at high concentrations. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=42674&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=42674&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1820″ NCI Thesaurus)
PDQ

A methylazirinopyrroloindoledione antineoplastic antibiotic isolated from the bacterium Streptomyces caespitosus and other Streptomyces bacterial species. Bioreduced mitomycin C generates oxygen radicals, alkylates DNA, and produces interstrand DNA cross-links, thereby inhibiting DNA synthesis. Preferentially toxic to hypoxic cells, mitomycin C also inhibits RNA and protein synthesis at high concentrations. (NCI04)
NCI

Price: $1.00

Loading Updating cart…

amidy

Organic compounds containing the -CO-NH2 radical. Amides are derived from acids by replacement of -OH by -NH2 or from ammonia by the replacement of H by an acyl group. (From Grant & Hackh`s Chemical Dictionary, 5th ed)
MSH

organic compound derived from ammonia by substituting an acyl radical for hydrogen, or from an acid by replacing the OH group by NH2.
CSP

Price: $1.00

Loading Updating cart…

amidiny

monovalent radical or any compound containing -C(NH)-NH2.
CSP

Price: $1.00

Loading Updating cart…

amidinotransferasy

Enzymes of a subclass of TRANSFERASES that catalyze the transfer of an amidino group from donor to acceptor. EC 2.1.4.
MSH

Price: $1.00

Loading Updating cart…

amidočerň

A dye used to stain proteins in electrophoretic techniques. It is used interchangeably with its acid form.
MSH

Price: $1.00

Loading Updating cart…

amidofosforibosyltransferasa

An enzyme, involved in the early steps of purine nucleotide biosynthesis, that catalyzes the formation of 5-phosphoribosylamine from glutamine and phosphoribosylpyrophosphate. EC 2.4.2.14.
MSH

The protein encoded by this gene is a member of the purine/pyrimidine phosphoribosyltransferase family. This protein is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosynthesis. This gene and PAICS/AIRC, a bifunctional enzyme catalyzing steps six and seven in the purine nucleotide biosynthesis pathway, are located in close proximity on chromosome 4. (from Gene)
NCI

Price: $1.00

Loading Updating cart…

amikacin

A broad-spectrum antibiotic derived from KANAMYCIN. It is reno- and oto-toxic like the other aminoglycoside antibiotics.
MSH

An antibiotic drug used to treat infection. It belongs to the family of drugs called aminoglycoside antibiotics.
NCI

A broad-spectrum semi-synthetic aminoglycoside antibiotic, derived from kanamycin with antimicrobial property. Amikacin irreversibly binds to the bacterial 30S ribosomal subunit, specifically locking 16S rRNA and S12 protein within the 30S subunit. This leads to interference with translational initiation complex and , misreading of mRNA, thereby hampering protein synthesis and resulting in bactericidal effect. This agent is usually used in short-term treatment of serious infections due to susceptible strains of Gram-negative bacteria.
NCI

Price: $1.00

Loading Updating cart…

Amikacin Sulfate

The sulfate salt of amikacin, a broad-spectrum semi-synthetic aminoglycoside antibiotic, derived from kanamycin with antimicrobial property. Amikacin irreversibly binds to the bacterial 30S ribosomal subunit, specifically in contact with 16S rRNA and S12 protein within the 30S subunit. This leads to interference with translational initiation complex and misreading of mRNA, thereby hampering protein synthesis and resulting in bactericidal effect. This agent is usually used in short-term treatment of serious infections due to susceptible strains of Gram-negative bacteria.
NCI

Price: $1.00

Loading Updating cart…

amilorid

A pyrazine compound inhibiting SODIUM reabsorption through SODIUM CHANNELS in renal EPITHELIAL CELLS. This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct. Negative potential reduces secretion of potassium and hydrogen ions. Amiloride is used in conjunction with DIURETICS to spare POTASSIUM loss. (From Gilman et al., Goodman and Gilman`s The Pharmacological Basis of Therapeutics, 9th ed, p705)
MSH

pyrazine compound inhibiting sodium reabsorbtion through sodium channels in renal epithelial cells; used in conjunction with diuretics to spare potassium loss.
CSP

A synthetic pyrazine derivative with antikaliuretic and diuretic properties. Amiloride inhibits sodium channels located in the distal tubules and collecting ducts of the kidney, thereby preventing the absorption of sodium and increasing its excretion along with water, to produce naturesis. In response to the hypernatremic conditions in the kidney, the plasma membrane becomes hyperpolarized and electrochemical forces are reduced, which then prevents the excretion of potassium and hydrogen into the lumen.
NCI

Price: $1.00

Loading Updating cart…

aminakrin

A highly fluorescent anti-infective dye used clinically as a topical antiseptic and experimentally as a mutagen, due to its interaction with DNA. It is also used as an intracellular pH indicator.
MSH

Price: $1.00

Loading Updating cart…

aminace

The creation of an amine. It can be produced by the addition of an amino group to an organic compound or reduction of a nitro group.
MSH

creation of an amine by the addition of an amino group to an organic compound or reduction of a nitro group.
CSP

Price: $1.00

Loading Updating cart…

aminy

A group of compounds derived from ammonia by substituting organic radicals for the hydrogens. (From Grant & Hackh`s Chemical Dictionary, 5th ed)
MSH

group of compounds derived from ammonia by substituting organic radicals for the hydrogens.
CSP

A class of organic compounds that contain nitrogen as the pivotal atom for functional groups. There are several different types of amines and the class is extensive.
NCI

Price: $1.00

Loading Updating cart…

Activation of Amino Acids

The modification of an amino acid to an active form, for incorporation into a peptide, protein or other macromolecule. [GOC:jl]
GO

A reaction that produces an “activated” amino acid derivative, such as amino acyl adenylate, or amino acylphosphorylate and provides energy for the amino acid to be incorporated into a peptide, protein, or other macromolecule.
MSH

Price: $1.00

Loading Updating cart…

chloromethylketony aminokyselin

Inhibitors of SERINE ENDOPEPTIDASES and sulfhydryl group-containing enzymes. They act as alkylating agents and are known to interfere in the translation process.
MSH

Price: $1.00

Loading Updating cart…

aminokyseliny – isomerasy

Enzymes that catalyze either the racemization or epimerization of chiral centers within amino acids or derivatives. EC 5.1.1.
MSH

Price: $1.00

Loading Updating cart…

aminokyseliny – vrozené poruchy metabolismu

Disorders affecting amino acid metabolism. The majority of these disorders are inherited and present in the neonatal period with metabolic disturbances (e.g., ACIDOSIS) and neurologic manifestations. They are present at birth, although they may not become symptomatic until later in life.
MSH

disorders affecting amino acid metabolism; majority of these disorders are inherited and present in the neonatal period with metabolic disturbances (for example, acidosis) and neurologic manifestations; present at birth, although they may not become symptomatic until later in life.
CSP

Price: $1.00

Loading Updating cart…

oxidoreduktasy aminokyselin

A class of enzymes that catalyze oxidation-reduction reactions of amino acids.
MSH

Price: $1.00

Loading Updating cart…

aminokyseliny – sekvence

The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION.
MSH

order of amino acids as they occur in a polypeptide chain.
CSP

The arrangement of amino acids in a protein. Proteins can be made from 20 different kinds of amino acids, and the structure and function of each type of protein are determined by the kinds of amino acids used to make it and how they are arranged.
NCI

The sequence of amino acids along a polypeptide chain.
NCI

Price: $1.00

Loading Updating cart…

aminokyseliny

Organic compounds that generally contain an amino (-NH2) and a carboxyl (-COOH) group. Twenty alpha-amino acids are the subunits which are polymerized to form proteins.
MSH

organic acid containing one or more amino groups, especially any of a group that make up proteins and are important to living cells; those that are nonessential can be synthesized by the body while essential acids must be obtained through the diet; there are also several important amino acids, such as the neurotransmitter g-aminobutyric acid, that have no relation to proteins.
CSP

One of several molecules that join together to form proteins. There are 20 common amino acids found in proteins.
NCI

Any organic compounds containing amino (-NH2) and carboxyl (-COOH) groups. In biochemistry, used to refer to the twenty-plus L-alpha-amino acids found in proteins.
NCI

Price: $1.00

Loading Updating cart…

aminokyseliny s postranními řetězci

Amino acids which have a branched carbon chain.
MSH

aminoacids which have a branched carbon chain.
CSP

Price: $1.00

Loading Updating cart…

aminokyseliny cyklické

A class of amino acids characterized by a closed ring structure.
MSH

any amino acid containing a ring structure.
CSP

Price: $1.00

Loading Updating cart…

aminokyseliny diaminové

dibasic amino acids.
CSP

Price: $1.00

Loading Updating cart…

aminokyseliny esenciální

Amino acids that are not synthesized by the human body in amounts sufficient to carry out physiological functions. They are obtained from dietary foodstuffs.
MSH

nine alpha amino acids required for protein synthesis that are not synthesized by the human body in amounts sufficient to carry out physiological functions; must be obtained from the diet.
CSP

Amino acid which is not efficiently synthesized by humans and must be included in the diet.
NCI

Refer to those amino acids that can not be synthesized in the body and can only be obtained through food supply.
NCI

Price: $1.00

Loading Updating cart…

aminokyseliny, peptidy a proteiny

Amino acids and chains of amino acids connected by peptide linkages.
MSH

Price: $1.00

Loading Updating cart…

aminokyseliny sírové

any aminoacid containing sulfur.
CSP

Price: $1.00

Loading Updating cart…

aminoacyl-tRNA-synthetasy

A subclass of enzymes that aminoacylate AMINO ACID-SPECIFIC TRANSFER RNA with their corresponding AMINO ACIDS.
MSH

Price: $1.00

Loading Updating cart…

aminoalkoholy

compounds possessing both a hydroxyl (-OH) and an amino group (-NH2).
CSP

Price: $1.00

Loading Updating cart…

aminocukry

SUGARS containing an amino group. GLYCOSYLATION of other compounds with these amino sugars results in AMINOGLYCOSIDES.
MSH

sugars containing an amino group in place of a hydroxyl group.
CSP

Price: $1.00

Loading Updating cart…