Additional pages

pohlavní identita

A person`s concept of self as being male and masculine or female and feminine, or ambivalent, based in part on physical characteristics, parental responses, and psychological and social pressures. It is the internal experience of gender role.
MSH

Price: $1.00

Loading Updating cart…

Porucha pohlavní identity

A disorder characterized by a strong and persistent cross-gender identification (such as stating a desire to be the other sex or frequently passing as the other sex) coupled with persistent discomfort with his or her sex (manifested in adults, for example, as a preoccupation with altering primary and secondary sex characteristics through hormonal manipulation or surgery).
NCI

Price: $1.00

Loading Updating cart…

role pohlaví

behavioral patterns expected from individuals by their social group believed to be typical of their sex; certain behavior patterns are culturally influenced, such as ascendance submissiveness, or occupational choices; sex role is often called psychosexual role.
CSP

Price: $1.00

Loading Updating cart…

geny – amplifikace

A selective increase in the number of copies of a gene coding for a specific protein without a proportional increase in other genes. It occurs naturally via the excision of a copy of the repeating sequence from the chromosome and its extrachromosomal replication in a plasmid, or via the production of an RNA transcript of the entire repeating sequence of ribosomal RNA followed by the reverse transcription of the molecule to produce an additional copy of the original DNA sequence. Laboratory techniques have been introduced for inducing disproportional replication by unequal crossing over, uptake of DNA from lysed cells, or generation of extrachromosomal sequences from rolling circle replication.
MSH

An increase in the number of copies of a gene. There may also be an increase in the RNA and protein made from that gene. Gene amplification is common in cancer cells, and some amplified genes may cause cancer cells to grow or become resistant to anticancer drugs. Genes may also be amplified in the laboratory for research purposes.
NCI

natural process where genes are reproduced into multiple copies to speed up expression; do NOT use this term to cover cloning or PCR.
CSP

Any DNA sequence rearrangement that results in the gain of one or more copies of a DNA segment that contains at least one gene.
NCI

Price: $1.00

Loading Updating cart…

geny – konverze

The asymmetrical segregation of genes during replication which leads to the production of non-reciprocal recombinant strands and the apparent conversion of one allele into another. Thus, e.g., the meiotic products of an Aa individual may be AAAa or aaaA instead of AAaa, i.e., the A allele has been converted into the a allele or vice versa.
MSH

the asymmetrical segregation of genes during replication which leads to the production of non-reciprocal recombinant strands and the apparent conversion of one allele into another.
CSP

A DNA recombination process that results in the unidirectional transfer of genetic material from a donor sequence to a highly homologous acceptor. [GOC:mah, PMID:17846636]
GO

Price: $1.00

Loading Updating cart…

geny – ztráta

A genetic rearrangement through loss of segments of DNA or RNA, bringing sequences which are normally separated into close proximity. This deletion may be detected using cytogenetic techniques and can also be inferred from the phenotype, indicating a deletion at one specific locus.
MSH

genetic rearrangement through loss of segments of DNA or RNA, bringing sequences which are normally separated into close proximity.
CSP

The loss of all or a part of a gene. There may also be a change in the RNA and protein made from that gene. Certain gene deletions are found in cancer and in other genetic diseases and abnormalities.
NCI

Any deletion mutation that occurs within a gene, including the 5` and 3` untranslated regions of the gene.
NCI

Price: $1.00

Loading Updating cart…

geny – duplikace

Processes occurring in various organisms by which new genes are copied. Gene duplication may result in a MULTIGENE FAMILY; supergenes or PSEUDOGENES.
MSH

the production of a tandem repeat of a DNA sequence by unequal crossing over or by an accident of replication.
CSP

Any DNA sequence rearrangement that results in the gain of copies of a genomic region, typically in the form of long interspersed sequences, short interspersed sequences, satellite sequences and retrotransposons. The appearance of duplications of DNA within the genome plays an important role in the diversification of genomes.
NCI

Price: $1.00

Loading Updating cart…

exprese genu

The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.
MSH

the phenotypic manifestation of a gene or genes by the processes of gene action.
CSP

The process in which a gene`s sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form. [GOC:dph, GOC:tb]
GO

The process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.
NCI

Typically involves transcription of genetically encoded information into an intermediary message (messenger RNA) and subsequent translation into a functional protein.
NCI

Price: $1.00

Loading Updating cart…

exprese genu – regulace

Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation.
MSH

Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene`s coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form. [GOC:dph, GOC:tb]
GO

Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene expression at the level of transcription or translation.
NCI

Any subcellular or molecular event or process that regulates transcription of a gene or processing of the transcription product.
NCI

Price: $1.00

Loading Updating cart…

exprese genu – regulace bakteriální

Any of the processes by which cytoplasmic or intercellular factors influence the differential control of gene action in bacteria.
MSH

Price: $1.00

Loading Updating cart…

exprese genu – regulace enzymatická

Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in enzyme synthesis.
MSH

Price: $1.00

Loading Updating cart…

exprese genu – regulace fungální

Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in fungi.
MSH

Price: $1.00

Loading Updating cart…

exprese genu – regulace leukemická

Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in leukemia.
MSH

Price: $1.00

Loading Updating cart…

exprese genu – regulace nádorová

Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in neoplastic tissue.
MSH

Price: $1.00

Loading Updating cart…

exprese genu – regulace virová

Any of the processes by which cytoplasmic factors influence the differential control of gene action in viruses.
MSH

Price: $1.00

Loading Updating cart…

geny – frekvence

The proportion of one particular in the total of all ALLELES for one genetic locus in a breeding POPULATION.
MSH

the relative occurrence of a specific allele at a given locus in a population, usually expressed in percent.
CSP

A description of the relative rate of occurrence of specific alleles, traits, or other factors within a population of organisms.
NCI

Price: $1.00

Loading Updating cart…

genová knihovna

A large collection of DNA fragments cloned (CLONING, MOLECULAR) from a given organism, tissue, organ, or cell type. It may contain complete genomic sequences (GENOMIC LIBRARY) or complementary DNA sequences, the latter being formed from messenger RNA and lacking intron sequences.
MSH

any well-defined collection of genetic material used to identify unknown nucleic acids; classically, a collection of expressed cDNA clones representing the genome of a particular organism, used to identify newly purified genes or mRNAs by hybridization.
CSP

Price: $1.00

Loading Updating cart…

genový pool

The total genetic information possessed by the reproductive members of a POPULATION of sexually reproducing organisms.
MSH

Price: $1.00

Loading Updating cart…

genové produkty env

Retroviral proteins, often glycosylated, coded by the envelope (env) gene. They are usually synthesized as protein precursors (POLYPROTEINS) and later cleaved into the final viral envelope glycoproteins by a viral protease.
MSH

Proteins that comprise the membrane or envelope that encapsulates a virus. These proteins often require proteolytic cleavage for functional activity.
NCI

Price: $1.00

Loading Updating cart…

genové produkty gag

Proteins coded by the retroviral gag gene. The products are usually synthesized as protein precursors or POLYPROTEINS, which are then cleaved by viral proteases to yield the final products. Many of the final products are associated with the nucleoprotein core of the virion. gag is short for group-specific antigen.
MSH

retroviral protein encoded by the gag gene; gag refers to group- specific antigen.
CSP

A protein that is a component of the retroviral core structure.
NCI

Price: $1.00

Loading Updating cart…

genové produkty nef

Products of the retroviral NEF GENE. They play a role as accessory proteins that influence the rate of viral infectivity and the destruction of the host immune system. nef gene products were originally found as factors that trans-suppress viral replication and function as negative regulators of transcription. nef stands for negative factor.
MSH

An integral component of HIV-1 particles. Nef facilitates a step in the viral life cycle occurring between penetration and reverse transcription (Aiken. Virology 1998; 248:139-147)
NCI

Price: $1.00

Loading Updating cart…

genové produkty pol

Retroviral proteins coded by the pol gene. They are usually synthesized as a protein precursor (POLYPROTEINS) and later cleaved into final products that include reverse transcriptase, endonuclease/integrase, and viral protease. Sometimes they are synthesized as a gag-pol fusion protein (FUSION PROTEINS, GAG-POL). pol is short for polymerase, the enzyme class of reverse transcriptase.
MSH

Price: $1.00

Loading Updating cart…

genové produkty rev

Trans-acting nuclear proteins whose functional expression are required for retroviral replication. Specifically, the rev gene products are required for processing and translation of the gag and env mRNAs, and thus rev regulates the expression of the viral structural proteins. rev can also regulate viral regulatory proteins. A cis-acting antirepression sequence (CAR) in env, also known as the rev-responsive element (RRE), is responsive to the rev gene product. rev is short for regulator of virion.
MSH

Price: $1.00

Loading Updating cart…

genová přestavba

The ordered rearrangement of gene regions by DNA recombination such as that which occurs normally during development.
MSH

covalent DNA changes in cells during normal differentiation resulting in new sequences, expression, or gene products; mechanism of binding site diversification for antibodies, certain receptors, and possibly other proteins.
CSP

Any DNA sequence rearrangement that results in the creation of a novel protein-coding capacity. Within certain genes, gene rearrangement is a normal part of development, facilitating the affinity maturation of B and T lymphocytes as well as class switching of immunoglobulins.
NCI

Price: $1.00

Loading Updating cart…

genová přestavba – alfa řetězec receptoru antigenů T-buněk

Ordered rearrangement of T-cell variable gene regions coding for the alpha-chain of antigen receptors.
MSH

Price: $1.00

Loading Updating cart…

genová přestavba B-lymfocytů

Ordered rearrangement of B-lymphocyte variable gene regions coding for the IMMUNOGLOBULIN CHAINS, thereby contributing to antibody diversity. It occurs during the differentiation of the IMMATURE B-LYMPHOCYTES.
MSH

Price: $1.00

Loading Updating cart…

genová přestavba – těžký řetězec B-lymfocytů

Ordered rearrangement of B-lymphocyte variable gene regions of the IMMUNOGLOBULIN HEAVY CHAINS, thereby contributing to antibody diversity. It occurs during the first stage of differentiation of the IMMATURE B-LYMPHOCYTES.
MSH

Price: $1.00

Loading Updating cart…

genová přestavba – lehký řetězec B-lymfocytů

Ordered rearrangement of B-lymphocyte variable gene regions coding for the kappa or lambda IMMUNOGLOBULIN LIGHT CHAINS, thereby contributing to antibody diversity. It occurs during the second stage of differentiation of the IMMATURE B-LYMPHOCYTES.
MSH

Price: $1.00

Loading Updating cart…

genová přestavba – beta řetězec receptoru antigenů T-buněk

Ordered rearrangement of T-cell variable gene regions coding for the beta-chain of antigen receptors.
MSH

Price: $1.00

Loading Updating cart…

genová přestavba – gama řetězec receptoru antigenů T-buněk

Ordered rearrangement of T-cell variable gene regions coding for the gamma-chain of antigen receptors.
MSH

Price: $1.00

Loading Updating cart…