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Ascaridia

A genus of nematode worms in the superfamily Heterakoidea. A. galli and A. lineata are important intestinal parasites of domestic fowl.
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askaridiáza

Infection with nematodes of the genus ASCARIDIA. This condition usually occurs in fowl, often manifesting diarrhea.
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Ascaridoidea

A superfamily of polymyarian nematode worms. An important characteristic of this group is the presence of three prominent lips around the mouth of the organism.
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Ascaris

genus of nematodes of the superfamily Ascaridoidea whose species usually inhabit the intestine.
CSP

A genus of nematodes of the superfamily ASCARIDOIDEA whose species usually inhabit the intestine.
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Ascaris lumbricoides

A species of parasitic nematode that is the largest found in the human intestine. Its distribution is worldwide, but it is more prevalent in areas of poor sanitation. Human infection with A. lumbricoides is acquired by swallowing fully embryonated eggs from contaminated soil.
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aorta ascendens

The portion of the aorta that emerges from the left ventricle and precedes the aortic arch.
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ascites

Accumulation or retention of free fluid within the peritoneal cavity.
MSH

effusion and accumulation of serous fluid in the abdominal cavity.
CSP

Abnormal buildup of fluid in the abdomen that may cause swelling. In late-stage cancer, tumor cells may be found in the fluid in the abdomen. Ascites also occurs in patients with liver disease.
NCI

A disorder characterized by accumulation of serous or hemorrhagic fluid in the peritoneal cavity.
NCI

An abnormal accumulation of serous fluid in the abdominal cavity
CHV

Accumulation of fluid in the peritoneal cavity. The fluid may be serous, hemorrhagic, or the result of tumor metastasis to the peritoneum.
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ascitická tekutina

The serous fluid of ASCITES, the accumulation of fluids in the PERITONEAL CAVITY.
MSH

Transudate contained in the peritoneal cavity.
UWDA

serous fluid which accumulates in the peritoneal cavity in ascites.
CSP

Transudate contained in the peritoneal cavity.
FMA

Pathological transudate in the peritoneal cavity.
UWDA

The small amount of fluid that is generated in the abdominal cavity to lubricate the peritoneum.
NCI

A liquid that is made in the abdominal cavity to lubricate the surface of the tissue that lines the abdominal wall and pelvic cavity and covers most of the organs in the abdomen.
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Ascomycota

A phylum of fungi which have cross-walls or septa in the mycelium. The perfect state is characterized by the formation of a saclike cell (ascus) containing ascospores. Most pathogenic fungi with a known perfect state belong to this phylum.
MSH

A phylum of fungi whose members are commonly known as the sac fungi.
NCI

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askorbátoxidasa

An enzyme that converts ascorbic acid to dehydroascorbic acid. EC 1.10.3.3.
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kyselina askorbová

A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant.
MSH

The functional and primary form of vitamin C; it is the enolic form of an alpha-ketolactone.
NCI

Vitamin C is an antioxidant. Antioxidants are substances that may protect your cells against the effects of free radicals. Free radicals are molecules produced when your body breaks down food, or by environmental exposures like tobacco smoke and radiation. Vitamin C is important for your skin, bones, and connective tissue. It promotes healing and helps the body absorb iron.

Vitamin C comes from fruits and vegetables. Good sources include citrus, red and green peppers, tomatoes, broccoli, and greens. Some juices and cereals have added vitamin C.

Some people may need extra vitamin C:

  • Pregnant/breastfeeding women
  • Smokers
  • People recovering from surgery
  • Burn victims


MEDLINEPLUS

A nutrient that the body needs in small amounts to function and stay healthy. Ascorbic acid helps fight infections, heal wounds, and keep tissues healthy. It is an antioxidant that helps prevent cell damage caused by free radicals (highly reactive chemicals). Ascorbic acid is found in all fruits and vegetables, especially citrus fruits, strawberries, cantaloupe, green peppers, tomatoes, broccoli, leafy greens, and potatoes. It is water-soluble (can dissolve in water) and must be taken in every day. Ascorbic acid is being studied in the prevention and treatment of some types of cancer.
NCI

A nutrient that the body needs in small amounts to function and stay healthy. Vitamin C helps fight infections, heal wounds, and keep tissues healthy. It is an antioxidant that helps prevent cell damage caused by free radicals (highly reactive chemicals). Vitamin C is found in all fruits and vegetables, especially citrus fruits, strawberries, cantaloupe, green peppers, tomatoes, broccoli, leafy greens, and potatoes. It is water-soluble (can dissolve in water) and must be taken in every day. Vitamin C is being studied in the prevention and treatment of some types of cancer.
NCI

A natural water-soluble vitamin (Vitamin C). Ascorbic acid is a potent reducing and antioxidant agent that functions in fighting bacterial infections, in detoxifying reactions, and in the formation of collagen in fibrous tissue, teeth, bones, connective tissue, skin, and capillaries. Found in citrus and other fruits, and in vegetables, vitamin C cannot be produced or stored by humans and must be obtained in the diet. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39737&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39737&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C285″ NCI Thesaurus)
PDQ

A natural water-soluble vitamin (Vitamin C). Ascorbic acid is a potent reducing and antioxidant agent that functions in fighting bacterial infections, in detoxifying reactions, and in the formation of collagen in fibrous tissue, teeth, bones, connective tissue, skin, and capillaries. Found in citrus and other fruits, and in vegetables, vitamin C cannot be produced or stored by humans and must be obtained in the diet. (NCI04)
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kyselina askorbová – nedostatek

A condition due to a dietary deficiency of ascorbic acid (vitamin C), characterized by malaise, lethargy, and weakness. As the disease progresses, joints, muscles, and subcutaneous tissues may become the sites of hemorrhage. Ascorbic acid deficiency frequently develops into SCURVY in young children fed unsupplemented cow`s milk exclusively during their first year. It develops also commonly in chronic alcoholism. (Cecil Textbook of Medicine, 19th ed, p1177)
MSH

condition due to a deficiency of vitamin C.
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asepse

The prevention of access by infecting organisms to the locus of potential infection.
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Asie

continent of the eastern hemisphere north of the equator forming a single landmass with Europe, the conventional dividing line being the Ural mountains; has numerous large offshore islands, some south of the equator.
CSP

The largest of the continents. It was known to the Romans more specifically as what we know today as Asia Minor. The name comes from at least two possible sources: from the Assyrian asu (to rise) or from the Sanskrit usa (dawn), both with reference to its being the land of the rising sun, i.e., eastern as opposed to Europe, to the west. (From Webster`s New Geographical Dictionary, 1988, p82 & Room, Brewer`s Dictionary of Names, 1992, p34)
MSH

The world`s largest continent; it occupies the eastern part of the Eurasian landmass and its adjacent islands and is separated from Europe by the Ural Mountains. (American Heritage Online Dictionary)
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Asie střední

The geographical area of Asia comprising KAZAKHSTAN; KYRGYZSTAN; TAJIKISTAN; TURKMENISTAN; and UZBEKISTAN. The desert region of Kara Kum (Qara Qum) is largely in Turkmenistan and the desert region of Kyzyl Kum (Kizil Kum or Qizil Qum), is in Uzbekistan and Kazakhstan. (From Webster`s New Geographical Dictionary, 1988, p233, 590, 636)
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Asie jihovýchodní

The geographical area of Asia comprising BORNEO; BRUNEI; CAMBODIA; INDONESIA; LAOS; MALAYSIA; the MEKONG VALLEY; MYANMAR (formerly Burma), the PHILIPPINES; SINGAPORE; THAILAND; and VIETNAM.
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Asie západní

The geographical designation for the countries of the MIDDLE EAST and the countries BANGLADESH; BHUTAN; INDIA; NEPAL; PAKISTAN; and SRI LANKA. (From Random House Unabridged Dictionary, 2d ed, 1993 & Webster`s New Geographical Dictionary, 1988)
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asialoglykoproteiny

Endogenous glycoproteins from which SIALIC ACID has been removed by the action of sialidases. They bind tightly to the ASIALOGLYCOPROTEIN RECEPTOR which is located on hepatocyte plasma membranes. After internalization by adsorptive ENDOCYTOSIS they are delivered to LYSOSOMES for degradation. Therefore receptor-mediated clearance of asialoglycoproteins is an important aspect of the turnover of plasma glycoproteins. They are elevated in serum of patients with HEPATIC CIRRHOSIS or HEPATITIS.
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Američané asijského původu

any person with Asian ethnic background whose home or birthplace is in the Americas.
CSP

Persons living in the United States having origins in any of the original peoples of the Far East, Southeast Asia, or the Indian subcontinent.
MSH

Denotes a person having origins in any of the original peoples of the Far East, Southeast Asia, or the Indian subcontinent, and who was either born in the United States or who was naturalized as a citizen of the United States.
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asparaginasa

A hydrolase enzyme that converts L-asparagine and water to L-aspartate and NH3. EC 3.5.1.1.
MSH

A drug that is used to treat acute lymphoblastic leukemia (ALL) and is being studied in the treatment of some other types of cancer. It is an enzyme taken from the bacterium Escherichia coli (E. coli). It breaks down the amino acid asparagine and may block the growth of tumor cells that need asparagine to grow.
NCI

An enzyme isolated from the bacterium Escherichia coli or the bacterium Erwinia carotovora. Asparagine is critical to protein synthesis in leukemic cells, which cannot synthesize this amino acid due to the absence of the enzyme asparagine synthase. Asparaginase hydrolyzes L-asparagine to L-aspartic acid and ammonia, thereby depleting leukemic cells of asparagine and blocking protein synthesis and tumor cell proliferation, especially in the G1 phase of the cell cycle. This agent also induces apoptosis in tumor cells. The E. carotovora-derived form of asparaginase is typically reserved for cases of asparaginase hypersensitivity. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=41146&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=41146&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C286″ NCI Thesaurus)
PDQ

An enzyme isolated from the bacterium Escherichia coli or the bacterium Erwinia carotovora with antileukemic activity. Asparaginase hydrolyzes L-asparagine to L-aspartic acid and ammonia in leukemic cells, resulting in the depletion of asparagine, inhibition of protein synthesis, cell cycle arrest in the G1 phase, and apoptosis in susceptible leukemic cell populations. Asparagine is critical to protein synthesis in leukemic cells; some leukemic cells cannot synthesize this amino acid de novo due to the absent or deficient expression of the enzyme asparagine synthase. The E. carotovora-derived form of asparaginase is typically reserved for cases of asparaginase hypersensitivity.
NCI

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asparagin

A non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue. It is biosynthesized from ASPARTIC ACID and AMMONIA by asparagine synthetase. (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed)
MSH

non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue; biosynthesized from aspartic acid and ammonia by asparagine synthetase.
CSP

Amino acid with side chain -CH2CONH2.
NCI

A non-essential amino acid in humans, Asparagine is a beta-amido derivative of aspartic acid and plays an important role in the biosynthesis of glycoproteins and other proteins. A metabolic precursor to aspartate, Asparagine is a nontoxic carrier of residual ammonia to be eliminated from the body. Asparagine acts as diuretic. (NCI04)
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asparaginsynthetasa

An enzyme that catalyzes the formation of asparagine from ammonia and aspartic acid, in the presence of ATP. EC 6.3.1.1.
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aspartam

Flavoring agent sweeter than sugar, metabolized as PHENYLALANINE and ASPARTIC ACID.
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aspartátaminotransferasy

Enzymes of the transferase class that catalyze the conversion of L-aspartate and 2-ketoglutarate to oxaloacetate and L-glutamate. EC 2.6.1.1.
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aspartátová amoniaklyasa

An enzyme that catalyzes the conversion of aspartic acid to ammonia and fumaric acid in plants and some microorganisms. EC 4.3.1.1.
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aspartátkarbamoyltransferasa

An enzyme that catalyzes the conversion of carbamoyl phosphate and L-aspartate to yield orthophosphate and N-carbamoyl-L-aspartate. (From Enzyme Nomenclature, 1992) EC 2.1.3.2.
MSH

Human CAD Gene (DHOase Family) encodes a trifunctional homohexameric cytoplasmic 2225-aa 243-kDa protein associated with the first 3 enzymatic activities of the 6-step de novo pyrimidine nucleotide biosynthesis pathway: Carbamoylphosphate Synthetase (GD-CPSASE), Aspartate Carbamoyltransferase, and Dihydroorotase, containing a CPSase domain and a type-1 glutamine amidotransferase domain. PRPP is a CAD activator and UMP is an inhibitor of CPSase. CAD is directly regulated allosterically by phosphorylation from the MAPK cascade.
NCI

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aspartátkinasa

An enzyme that catalyzes the formation of beta-aspartyl phosphate from aspartic acid and ATP. Threonine serves as an allosteric regulator of this enzyme to control the biosynthetic pathway from aspartic acid to threonine. EC 2.7.2.4.
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aspartátsemialdehyddehydrogenasa

An enzyme that catalyzes the conversion of L-aspartate 4-semialdehyde, orthophosphate, and NADP+ to yield L-4-aspartyl phosphate and NADPH. EC 1.2.1.11.
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kyselina aspartová

One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
MSH

Amino acid with side chain -CH2COO-.
NCI

A non-essential amino acid in humans, Aspartic Acid has an overall negative charge and plays an important role in the synthesis of other amino acids and in the citric acid and urea cycles. Asparagine, arginine, lysine, methionine, isoleucine, and some nucleotides are synthesized from aspartic acid. Aspartic acid also serves as a neurotransmitter. (NCI04)
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dehydrogenasa aspartokinasy homoserinu

An enzyme complex consisting of aspartokinase, EC 2.7.2.4, and homoserine dehydrogenase, EC 1.1.1.3. The complex has been isolated from E. coli and consists of four identical subunits with a molecular weight of 85,000. The enzyme complex is involved in the biosynthesis of amino acids of the aspartate family.
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