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Hallermannův syndrom

An oculomandibulofacial syndrome principally characterized by dyscephaly (usually brachycephaly), parrot nose, mandibular hypoplasia, proportionate nanism, hypotrichosis, bilateral congenital cataracts, and microphthalmia. (Dorland, 27th ed)
MSH

A very rare syndrome characterized by multiple congenital abnormalities including abnormally shaped head, mandibular hypoplasia, parrot nose, bilateral congenital cataracts, microphthalmia, dwarfism and hypotrichosis.
NCI

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Hallervordenův-Spatzův syndrom

A rare autosomal recessive degenerative disorder which usually presents in late childhood or adolescence. Clinical manifestations include progressive MUSCLE SPASTICITY; hyperreflexia; MUSCLE RIGIDITY; DYSTONIA; DYSARTHRIA; and intellectual deterioration which progresses to severe dementia over several years. (From Adams et al., Principles of Neurology, 6th ed, p972; Davis & Robertson, Textbook of Neuropathology, 2nd ed, pp972-929)
MSH

A rare autosomal recessive inherited disorder caused by mutations in the PANK2 gene. It is characterized by abnormal accumulation of iron in the basal ganglia. Signs and symptoms include progressive motor disturbances, muscle spasm and rigidity, dysarthria, mental deterioration, and behavioral changes.
NCI

A rare neuroaxonal dystrophy, histologically characterized by axonal spheroids, iron deposition, lewy body (LB)-like intraneuronal inclusions and neurofibrillary tangles.
NCI

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halucinace

Subjectively experienced sensations in the absence of an appropriate stimulus, but which are regarded by the individual as real. They may be of organic origin or associated with MENTAL DISORDERS.
MSH

subjectively experienced sensations in the absence of an appropriate stimulus, but which are regarded by the individual as real; may be of organic origin, drug induced, or associated with a mental disorder.
CSP

A disorder characterized by a false sensory perception in the absence of an external stimulus.
NCI

a false sensory perception in the absence of an external stimulus
CHV

A sight, sound, smell, taste, or touch that a person believes to be real but is not real. Hallucinations can be caused by nervous system disease, certain drugs, or mental disorders.
NCI

A false sensory perception in the absence of an external stimulus, as distinct from an illusion which is a misperception of an external stimulus.
NCI

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Závislost na halucinogenech, blíže neurčené užívání

A drug dependence for a hallucinogenic substance.
NCI

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halucinogeny

Drugs capable of inducing illusions, hallucinations, delusions, paranoid ideations, and other alterations of mood and thinking. Despite the name, the feature that distinguishes these agents from other classes of drugs is their capacity to induce states of altered perception, thought, and feeling that are not experienced otherwise.
MSH

class of drugs capable of inducing illusions, hallucinations, delusions, paranoid ideations, and other alterations of mood and thinking; the feature that distinguishes these agents from other classes of drugs is their capacity to induce states of altered perception, thought, and feeling that are not experienced otherwise.
CSP

drugs which produce a state similar to that of psychosis.
CSP

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hallux valgus

Lateral displacement of the great toe (HALLUX), producing deformity of the first METATARSOPHALANGEAL JOINT with callous, bursa, or bunion formation over the bony prominence.
MSH

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Halobacteriaceae

family of extremely halophilic archaea found in environments with high salt concentrations, such as salt lakes, evaporated brines, or salted fish; Halobacteriaceae are either obligate aerobes or facultative anaerobes and are divided into six genera: Haloarcula, Halobacterium, Halococcus, Haloferax, Natronobacterium, and Natronococcus.
CSP

A family of extremely halophilic archaea found in environments with high salt concentrations, such as salt lakes, evaporated brines, or salted fish. Halobacteriaceae are either obligate aerobes or facultative anaerobes and are divided into at least twenty-six genera including: HALOARCULA; HALOBACTERIUM; HALOCOCCUS; HALOFERAX; HALORUBRUM; NATRONOBACTERIUM; and NATRONOCOCCUS.
MSH

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Halobacterium

A genus of HALOBACTERIACEAE whose growth requires a high concentration of salt. Binary fission is by constriction.
MSH

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halofenát

An antihyperlipoproteinemic agent and uricosuric agent.
MSH

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halogeny

A family of nonmetallic, generally electronegative, elements that form group 17 (formerly group VIIa) of the periodic table.
MSH

elements of Group VII of the periodic table.
CSP

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haloperidol

A phenyl-piperidinyl-butyrophenone that is used primarily to treat SCHIZOPHRENIA and other PSYCHOSES. It is also used in schizoaffective disorder, DELUSIONAL DISORDERS, ballism, and TOURETTE SYNDROME (a drug of choice) and occasionally as adjunctive therapy in INTELLECTUAL DISABILITY and the chorea of HUNTINGTON DISEASE. It is a potent antiemetic and is used in the treatment of intractable HICCUPS. (From AMA Drug Evaluations Annual, 1994, p279)
MSH

USP lists as an antipsychotic and as an “antidyskinetic” used in Tourette syndrome.
CSP

A drug used to treat certain mental and neurological disorders. It is also being studied in the treatment of nausea and vomiting caused by some cancer treatments. It is a type of antiemetic and a type of antipsychotic.
NCI

A phenylbutylpiperadine derivative with antipsychotic, neuroleptic and antiemetic effects. Haloperidol competitively blocks postsynaptic dopamine (D2) receptors in the mesolimbic system of the brain, thereby eliminating dopamine neurotransmission and leading to antidelusionary and antihallucinagenic effects. The antagonistic activity mediated through D2 dopamine receptors in the chemoreceptive trigger zone (CTZ) accounts for its antiemetic activity. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39474&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39474&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C537″ NCI Thesaurus)
PDQ

A phenylbutylpiperadine derivative with antipsychotic, neuroleptic, and antiemetic activities. Haloperidol competitively blocks postsynaptic dopamine (D2) receptors in the mesolimbic system of the brain, thereby eliminating dopamine neurotransmission and leading to antidelusionary and antihallucinagenic effects. Antagonistic activity mediated through D2 dopamine receptors in the chemoreceptive trigger zone (CTZ) accounts for its antiemetic activity.
NCI

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halothan

A nonflammable, halogenated, hydrocarbon anesthetic that provides relatively rapid induction with little or no excitement. Analgesia may not be adequate. NITROUS OXIDE is often given concomitantly. Because halothane may not produce sufficient muscle relaxation, supplemental neuromuscular blocking agents may be required. (From AMA Drug Evaluations Annual, 1994, p178)
MSH

potent inhalation anesthetic widely used for induction and maintenance of general anesthesia.
CSP

A nonflammable, halogenated, hydrocarbon and general inhalation anesthetic. Although the exact mechanism of action is unknown, halothane provides relatively rapid induction of anesthesia by depressing the central nervous system, thereby producing a reversible loss of consciousness and sensation. (NCI05)
NCI

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hamartom

A focal malformation resembling a neoplasm, composed of an overgrowth of mature cells and tissues that normally occur in the affected area.
MSH

A benign (not cancer) growth made up of an abnormal mixture of cells and tissues normally found in the area of the body where the growth occurs.
NCI

A benign and excessive tumor-like growth of mature cells and normal tissues which grow in a disorganized pattern.
NCI

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syndrom mnohočetného hamartomu

A hereditary disease characterized by multiple ectodermal, mesodermal, and endodermal nevoid and neoplastic anomalies. Facial trichilemmomas and papillomatous papules of the oral mucosa are the most characteristic lesions. Individuals with this syndrome have a high risk of BREAST CANCER; THYROID CANCER; and ENDOMETRIAL CANCER. This syndrome is associated with mutations in the gene for PTEN PHOSPHATASE.
MSH

An inherited disorder marked by the formation of many noncancerous growths called hamartomas. These growths occur in the skin, breast, thyroid, colon, intestines, and inside of the mouth. Patients with Cowden syndrome are at increased risk of certain types of cancer, including breast and thyroid.
NCI

An autosomal dominant hereditary syndrome characterized by a variety of hamartomas and neoplasms including verrucous skin lesions, fibromas of the oral cavity, facial trichilemmomas, hamartomatous colonic polyps, thyroid neoplasms, breast cancer, and dysplastic gangliocytomas of the cerebellum.
NCI

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Dwerghamsters, Chinese

Originating in the deserts of northern China and Mongolia and kept in captivity since 1919, these hamsters exhibit a whitish/grey/brown coat color with a black stripe down the spine, and have a life span of two to three years. The Chinese hamster has a relatively long thin body and tail in comparison to other hamster breeds and is crepuscular year round in captivity. Of note, Chinese hamster ovary cell lines are highly transfectable and are used in a variety of pre-clinical research applications.
NCI

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Cricetinae

any of a subfamily (Cricetinae) of small Old World rodents having very large cheek pouches.
CSP

Any member of four genera of the rodent family Cricetidae; short-tailed Old World burrowing rodents with large cheek pouches.
NCI

A subfamily in the family MURIDAE, comprising the hamsters. Four of the more common genera are Cricetus, CRICETULUS; MESOCRICETUS; and PHODOPUS.
MSH

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křeček zlatý

All Syrian hamsters in captivity are derived from a mother and eight pups that were captured in the wild in Aleppo, Syria by Dr. Israel Aharoni in 1930. Syrian Hamsters exhibit multiple coat colors, gold being the most common, and have a life span of about two to three years. Syrian hamsters are extremely territorial and are prone to attacking other hamsters so cannot be housed together under most circumstances. Females come into estrus every four days and embryo gestation is 16-18 days long. Syrian hamsters may exhibit diarrhea, neoplasms, amyloidosis, polycystic disease, and pregnancy-associated toxemia.
NCI

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ruka

part of the upper limb distal to the wrist including carpus, metacarpus and fingers.
CSP

The distal portion of the upper extremity. It consists of the carpus, metacarpus, and digits. (NCI)
NCI

The distal portion of the upper extremity. It consists of the carpus, metacarpus, and digits.
NCI

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ruka – deformity

Alterations or deviations from normal shape or size which result in a disfigurement of the hand.
MSH

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ruka – deformity získané

Deformities of the hand, or a part of the hand, acquired after birth as the result of injury or disease.
MSH

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ruka – deformity vrozené

Alterations or deviations from normal shape or size which result in a disfigurement of the hand occurring at or before birth.
MSH

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ruka – poranění

General or unspecified injuries to the hand.
MSH

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nemoc rukou, nohou a úst

A mild, highly infectious viral disease of children, characterized by vesicular lesions in the mouth and on the hands and feet. It is caused by coxsackieviruses A.
MSH

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postižení

persons with physical or mental disabilities that affect or limit their activities of daily living and that may require special accommodations.
CSP

Indication of disability.


HL7V3.0

Groups with similar restrictions or lack or ability to perform physical or mental activities in a manner or within the range considered normal for a human being.
NCI

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handling (psychologie)

Physical manipulation of animals and humans to induce a behavioral or other psychological reaction. In experimental psychology, the animal is handled to induce a stress situation or to study the effects of “gentling” or “mothering”.
MSH

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mytí rukou

The act of cleansing the hands with water or other liquid, with or without the inclusion of soap or other detergent, for the purpose of removing soil or microorganisms.
MSH

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haploidie

The chromosomal constitution of cells, in which each type of CHROMOSOME is represented once. Symbol: N.
MSH

chromosomal constitution of cells, in which each type of chromosome is represented once.
CSP

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haplotypy

The genetic constitution of individuals with respect to one member of a pair of allelic genes, or sets of genes that are closely linked and tend to be inherited together such as those of the MAJOR HISTOCOMPATIBILITY COMPLEX.
MSH

A way of denoting the collective genotype of a number of closely linked loci on a chromosome.
NCI

A set of closely linked genetic markers present on one chromosome which tend to be inherited together.
NCI

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štěstí

Highly pleasant emotion characterized by outward manifestations of gratification; joy.
MSH

The feeling of being pleased and content.
NCI

A feeling of delight.
NCI

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hapteny

Small antigenic determinants capable of eliciting an immune response only when coupled to a carrier. Haptens bind to antibodies but by themselves cannot elicit an antibody response.
MSH

substances which can act as an epitope for antibody but lack immunogenicity unless coupled to a larger carrier molecule.
CSP

A substance that can act as an epitope for an antibody but that lacks immunogenicity unless coupled to a larger carrier molecule.
NCI

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