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horko

high temperature; quality of being hot or warm.
CSP

The form of energy and the sensation of an increase in temperature. Its interest in medicine is largely with reference to its physiological effects, its therapeutic use, and its use in procedures in physics and physical chemistry.
MSH

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vyčerpání z tepla

A clinical syndrome caused by heat stress, such as over-exertion in a hot environment or excessive exposure to sun. It is characterized by SWEATING, water (volume) depletion, salt depletion, cool clammy skin, NAUSEA, and HEADACHE.
MSH

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termogeneze

heat production in the body by muscular activity (e.g. shivering), food intake, or increased metabolic rate, frequently hormonally regulated.
CSP

The generation of heat in order to maintain body temperature. The uncoupled oxidation of fatty acids contained within brown adipose tissue and SHIVERING are examples of thermogenesis in MAMMALS.
MSH

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úpal

A condition caused by the failure of body to dissipate heat in an excessively hot environment or during PHYSICAL EXERTION in a hot environment. Contrast to HEAT EXHAUSTION, the body temperature in heat stroke patient is dangerously high with red, hot skin accompanied by DELUSIONS; CONVULSIONS; or COMA. It can be a life-threatening emergency and is most common in infants and the elderly.
MSH

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proteiny tepelného šoku HSP27

A subfamily of small heat-shock proteins that function as molecular chaperones that aid in refolding of non-native proteins. They play a protective role that increases cellular survival during times of stress.
MSH

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proteiny tepelného šoku

Proteins which are synthesized in eukaryotic organisms and bacteria in response to hyperthermia and other environmental stresses. They increase thermal tolerance and perform functions essential to cell survival under these conditions.
MSH

family of highly conserved, specific proteins produced by prokaryotic and eukaryotic cells in response to heat shock or other stressor; some may protect other proteins from denaturation or degradation.
CSP

any of a group of proteins that are synthesized in response to hyperthermia, hypoxia, or other stresses and that are believed to enable cells to recover from these stresses, perhaps by enabling recovery of gene expression; occur in prokaryotes and eukaryotes, and at least some proteins are similar in vertebrates and invertebrates.
CSP

One of a group of proteins that help protect cells from stresses such as heat, cold, and low amounts of oxygen or glucose (sugar). Heat-shock proteins help other proteins function in normal cells and may be present at high levels in cancer cells. Blocking the activity of a heat-shock protein called HSP90 is being studied in the treatment of cancer. Other heat-shock proteins including HSP70 and gp96 are being studied in vaccines to treat cancer.
NCI

A family of highly-conserved proteins that are synthesized in response to hyperthermia (heat shock), hypoxia, or other stresses that appear to increase cellular thermal tolerance and enable cells to recover from stress. Some heat shock proteins may protect other proteins from denaturation, degradation or perform functions essential to cell survival under these conditions.
NCI

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vytápění

The application of heat to raise the temperature of the environment, ambient or local, or the systems for accomplishing this effect. It is distinguished from HEAT, the physical property and principle of physics.
MSH

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nemoc těžkých řetězců

A disorder of immunoglobulin synthesis in which large quantities of abnormal heavy chains are excreted in the urine. The amino acid sequences of the N-(amino-) terminal regions of these chains are normal, but they have a deletion extending from part of the variable domain through the first domain of the constant region, so that they cannot form cross-links to the light chains. The defect arises through faulty coupling of the variable (V) and constant (C) region genes.
MSH

disorder of immunoglobulin synthesis in which large quantities of abnormal heavy chains are excreted in the urine; amino acid sequences of the N-(amino-) terminal regions of these chains are normal, but they have a deletion extending from part of the variable domain through the first domain of the constant region, so that they cannot form cross-links to the light chains; the defect arises through faulty coupling of the variable (V) and constant (C) region genes.
CSP

One of a group of rare disorders of immunoglobulin synthesis associated with B-cell proliferative disorders and diagnosed by the finding of heavy chains in the serum, urine, or both. Heavy chains are immunologically related to the Fc fragment of the immunoglobulin chain. Three types of heavy chain disease (HCD) have been recognized: gamma heavy chain disease (associated with Waldenstrom`s macroglobulinemia), alpha heavy chain disease (also known as immunoproliferative small intestinal disease or Mediterranean lymphoma), and mu heavy chain disease (associated with chronic lymphocytic leukemia). Complications of HCD vary depending upon type.
NCI

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Gamma-ketenziekte

A clonal disorder characterized by the secretion of a truncated gamma chain. In most cases, it is associated with morphologic changes also seen in lymphoplasmacytic lymphomas, but the clinical course is typically more aggressive than in lymphoplasmacytic lymphoma/Waldenstrom`s macroglobulinemia. –2004
NCI

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Hebridy

A group of islands in the Atlantic Ocean west of Scotland, comprising the Outer Hebrides and the Inner Hebrides. They were the scene of frequent incursions of Scandinavian settlers from the 6th century A.D. They were ceded to Scotland by Norway in the 13th century. The origin of the name is uncertain. It is suggested that it is the result of a miscopying of the Roman name Ebudae or Hebudae with ri for u. (From Webster`s New Geographical Dictionary, 1988, p496 & Room, Brewer`s Dictionary of Names, 1992, p235)
MSH

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ježci

The family Erinaceidae, in the order INSECTIVORA. Most are true hedgehogs possessing a coat of spines and a very short tail. Those members of the family found in Southeast Asia (moonrats or gymnures) have normal body hair and a long tail.
MSH

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Heinzova tělíska

Abnormal intracellular inclusions, composed of denatured hemoglobin, found on the membrane of red blood cells. They are seen in thalassemias, enzymopathies, hemoglobinopathies, and after splenectomy.
MSH

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Hela buňky

first continuously cultured human malignant cell line, derived from a cervical carcinoma; used for virus cultivation and antitumor drug screening assays.
CSP

The first continuously cultured human malignant CELL LINE, derived from the cervical carcinoma of Henrietta Lacks. These cells are used for VIRUS CULTIVATION and antitumor drug screening assays.
MSH

HeLa cells were developed from cervix adenocarcinoma of a 31-year-old Black female. The cells are positive for keratin by immunoperoxidase staining. HeLa cells have been reported to contain human papilloma virus 18 (HPV-18) sequences. P53 expression was reported to be low, and normal levels of pRB (retinoblastoma suppressor) were found. Four typical HeLa marker chromosomes have been reported. M1 is a rearranged long arm and centromere of chromosome 1 and the long arm of chromosome 3. M2 is a combination of short arm of chromosome 3 and long arm of chromosome 5. M3 is an isochromosome of the short arm of chromosome 5. M4 consists of the long arm of chromosome 11 and an arm of chromosome 19. HeLa Marker Chromosomes: One copy of Ml, one copy of M2, four-five copies of M3, and two copies of M4 as revealed by G-banding patterns.
NCI

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Helianthus

A genus of tall, erect American herbs of the Compositae. The seeds yield oil and are used as food and animal feed; the roots of Helianthus tuberosum (Jerusalem artichoke) are edible.
MSH

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Heligmosomatoidea

A superfamily of parasitic nematodes which were formerly considered a part of TRICHOSTRONGYLOIDEA. It includes the following genera: Heligmosomum, NEMATOSPIROIDES, and NIPPOSTRONGYLUS. The hosts are rodents.
MSH

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helioterapie

The treatment of disease by exposing the body to SUNLIGHT, a therapeutic use of SUNBATHING.
MSH

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helium

Helium. A noble gas with the atomic symbol He, atomic number 2, and atomic weight 4.003. It is a colorless, odorless, tasteless gas that is not combustible and does not support combustion. It was first detected in the sun and is now obtained from natural gas. Medically it is used as a diluent for other gases, being especially useful with oxygen in the treatment of certain cases of respiratory obstruction, and as a vehicle for general anesthetics. (Dorland, 27th ed)
MSH

noble gas with the atomic symbol He, atomic number 2, and atomic weight 4.003; a colorless, odorless, tasteless gas that is not combustible and does not support combustion; medically it is used as a diluent for other gases, being especially useful with oxygen in the treatment of certain cases of respiratory obstruction, and as a vehicle for general anesthetics.
CSP

A gaseous element with atomic symbol He, atomic number 2, and atomic weight 4.00.
NCI

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Helix (hlemýždi)

A genus of chiefly Eurasian and African land snails including the principal edible snails as well as several pests of cultivated plants.
MSH

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červi – proteiny

Proteins found in any species of helminth.
MSH

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helmintóza

Infestation with parasitic worms of the helminth class.
MSH

diseases caused by parasitic worms of the helminth class.
CSP

A parasitic infection characterized by the infestation with worms, mainly in the intestine.
NCI

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helmintiáza zvířat

Infestation of animals with parasitic worms of the helminth class. The infestation may be experimental or veterinary.
MSH

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Helminthosporium

A mitosporic fungal genus including both saprophytes and plant parasites.
MSH

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červi

Commonly known as parasitic worms, this group includes the ACANTHOCEPHALA; NEMATODA; and PLATYHELMINTHS. Some authors consider certain species of LEECHES that can become temporarily parasitic as helminths.
MSH

a type of parasite
CHV

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T-lymfocyty pomocné-indukující

Subpopulation of CD4+ lymphocytes that cooperate with other lymphocytes (either T or B) to initiate a variety of immune functions. For example, helper-inducer T-cells cooperate with B-cells to produce antibodies to thymus-dependent antigens and with other subpopulations of T-cells to initiate a variety of cell-mediated immune functions.
MSH

subpopulation of CD4+ lymphocytes that cooperate with other lymphocytes (either T or B) to initiate a variety of immune functions; for example, helper-inducer T-cells cooperate with B-cells to produce antibodies to thymus-dependent antigens and with other subpopulations of T-cells to initiate a variety of cell-mediated immune functions.
CSP

A type of white blood cell that helps stimulate immune system reactions. Helper T cells help activate cytotoxic T cells and macrophages by secreting cytokines. They also stimulate B cells to make antibodies.
NCI

A subpopulation of CD4+ lymphocytes that cooperate with other lymphocytes (either T or B) to initiate a variety of immune functions. (MeSH)
NCI

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viry pomocné

Viruses which enable defective viruses to replicate or to form a protein coat by complementing the missing gene function of the defective (satellite) virus. Helper and satellite may be of the same or different genus.
MSH

a virus which provides the factor(s) needed by a defective virus for replication; for certain plant virus complexes the term refers to the virus which confers insect transmissibility to the complex.
CSP

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pomáhající chování

Behaviors associated with the giving of assistance or aid to individuals.
MSH

The act of contributing to the fulfillment of a need or furtherance of an effort.
NCI

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bezmocnost naučená

Learned expectation that one`s responses are independent of reward and, hence, do not predict or control the occurrence of rewards. Learned helplessness derives from a history, experimentally induced or naturally occurring, of having received punishment/aversive stimulation regardless of responses made. Such circumstances result in an impaired ability to learn. Used for human or animal populations. (APA, Thesaurus of Psychological Index Terms, 1994)
MSH

exposure to adverse and uncontrollable events often causes the reaction of helplessness; symptoms include: difficulty in learning behavior patterns in reaction to controllable adversities, reduced motivation in initiating coping responses, and emotional reactions of sadness or depression.
CSP

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Helsinská deklarace

An international agreement of the World Medical Association which offers guidelines for conducting experiments using human subjects. It was adopted in 1962 and revised by the 18th World Medical Assembly at Helsinki, Finland in 1964. Subsequent revisions were made in 1975, 1983, 1989, and 1996. (From Encyclopedia of Bioethics, rev ed, 1995)
MSH

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hemadsorpce

A phenomenon manifested by an agent or substance adhering to or being adsorbed on the surface of a red blood cell, as tuberculin can be adsorbed on red blood cells under certain conditions. (Stedman, 25th ed)
MSH

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hemaglutinace

The aggregation of ERYTHROCYTES by AGGLUTININS, including antibodies, lectins, and viral proteins (HEMAGGLUTINATION, VIRAL).
MSH

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