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Hexokinase 2

Expressed in human heart, skeletal muscle, and adipose tissue and encoded by insulin-responsive HK2 Gene (Hexokinase Family), outer mitochondrial membrane-bound 917-amino acid 102-kD monomeric Hexokinase 2 promotes glycolysis. HK2 contains glucose- and ATP-binding sites and a hexokinase domain. The C-terminus contains catalytic activity; membrane binding and regulation associate with the N-terminus. Allosterically regulated by product, HK2 converts aldo-/keto-hexoses to hexose-6-phosphate, the first step of many metabolic pathways. (from LocusLink, Swiss-Prot, OMIM, and NCI)
NCI

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hexoprenalin

Stimulant of adrenergic beta 2 receptors. It is used as a bronchodilator, antiasthmatic agent, and tocolytic agent.
MSH

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Hexosamine

six carbon aminosugar.
CSP

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hexosaminidasa B

A mammalian beta-hexosaminidase isoform that is comprized of hexosaminidase beta subunits. Deficiency of hexosaminidase B due to mutations in the gene encoding the hexosaminidase beta subunit is a case of SANDHOFF DISEASE.
MSH

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hexosaminidasy

Enzymes that catalyze the hydrolysis of N-acylhexosamine residues in N-acylhexosamides. Hexosaminidases also act on GLUCOSIDES; GALACTOSIDES; and several OLIGOSACCHARIDES.
MSH

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UDPglukosa-hexosa-1-fosfáturidylyltransferasa

An enzyme that catalyzes the transfer of UMP from UDPglucose to galactose 1-phosphate, forming UDPgalactose and glucose 1-phosphate. Deficiency in this enzyme is the major cause of GALACTOSEMIA. EC 2.7.7.12.
MSH

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hexosy

monosaccharide containing six carbon atoms in one molecule.
CSP

A class of monosaccharides with six carbon atoms.
NCI

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hexosyltransferasy

Enzymes that catalyze the transfer of hexose groups. EC 2.4.1.-.
MSH

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kyseliny hexuronové

Term used to designate tetrahydroxy aldehydic acids obtained by oxidation of hexose sugars, i.e. glucuronic acid, galacturonic acid, etc. Historically, the name hexuronic acid was originally given to ascorbic acid.
MSH

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hexylresorcinol

A substituted dihydroxybenzene that is used topically as an antiseptic for the treatment of minor skin infections.
MSH

A substituted phenol with bactericidal, antihelminthic and potential antineoplastic activities. Hexylresorcinol is used as an antiseptic in mouthwashes and skin wound cleansers. Hexylresorcinol may also inhibit oxidative DNA damage by enhancing the activity of antioxidant enzymes, including glutathione peroxidase and glutathione reductase, which facilitate scavenging reactive oxygen molecules by glutathione (GSH).
NCI

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hibernace

The dormant state in which some warm-blooded animal species pass the winter. It is characterized by narcosis and by sharp reduction in body temperature and metabolic activity and by a depression of vital signs.
MSH

state of physical and metabolic dormancy exhibited by some warm blooded animals at seasonal intervals, characterized by lowered heart rate and body temperature (which fluctuates with the ambient), and nutritionally driven by stored body fat.
CSP

Any process in which an organism enters and maintains a period of dormancy in which to pass the winter. It is characterized by narcosis and by sharp reduction in body temperature and metabolic activity and by a depression of vital signs. [GOC:jl, PMID:1945046]
GO

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škytavka

A spasm of the diaphragm that causes a sudden inhalation followed by rapid closure of the glottis which produces a sound.
MSH

A disorder characterized by repeated gulp sounds that result from an involuntary opening and closing of the glottis. This is attributed to a spasm of the diaphragm.
NCI

A diaphragmatic spasm causing a sudden inhalation which is interrupted by a spasmodic closure of the glottis, producing a noise. (On-line Medical Dictionary)
NCI

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adenom potní žlázy

A benign neoplasm derived from epithelial cells of sweat glands. (Stedman, 25th ed)
MSH

A benign epithelial neoplasm arising from the sweat glands. Variants include the clear cell and nodular hidradenoma.
NCI

A benign epithelial neoplasm arising from the sweat glands. Representative examples include tubular apocrine adenoma, syringofibroadenoma, and hidradenoma.
NCI

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hierarchie sociální

Social rank-order established by certain behavioral patterns.
MSH

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proteiny s vysokou pohyblivostí

A family of low-molecular weight, non-histone proteins found in chromatin.
MSH

The High Mobility Group (HMG) proteins were originally isolated from mammalian cells, named according to their electrophoretic mobility in polyacrylamide gels, and were arbitrarily classed as a specific type of non-histone proteins based on the observation that they are ubiquitous to mammalian cells, that they share certain physical properties, and that they are associated with isolated chromatin. Those mammalian proteins considered to be Canonical HMG proteins are now subdivided into 3 superfamilies: the HMGB (formerly HMG-1/-2) family, the HMGN (formerly HMG-14/-17) family, and the HMGA (formerly HMG-I/Y/C) family. Each HMG family has a characteristic functional sequence motif. (www.informatics.jax.org/mgihome/nomen/genefamilies/hmgfamily.shtml)
NCI

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kininogen vysokomolekulární

A plasma protein, molecular weight of 110 kD, that normally exists in plasma in a 1:1 complex with PREKALLIKREIN. HMWK is split by plasma kallikrein to produce BRADYKININ. The complex is a cofactor in the activation of coagulation factor XII. The product of this reaction, XIIa, in turn activates prekallikrein to KALLIKREINS. (From Stedman, 26th ed)
MSH

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hypertenzní neurologický syndrom

A syndrome related to increased atmospheric pressure and characterized by tremors, nausea, dizziness, decreased motor and mental performance, and SEIZURES. This condition may occur in those who dive deeply (c. 1000 ft) usually while breathing a mixture of oxygen and helium. The condition is associated with a neuroexcitatory effect of helium.
MSH

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vysokofrekvenční proudová ventilace

Respiratory support system used primarily with rates of about 100 to 200/min with volumes of from about one to three times predicted anatomic dead space. Used to treat respiratory failure and maintain ventilation under severe circumstances.
MSH

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vysokofrekvenční ventilace

Ventilatory support system using frequencies from 60-900 cycles/min or more. Three types of systems have been distinguished on the basis of rates, volumes, and the system used. They are high frequency positive-pressure ventilation (HFPPV); HIGH-FREQUENCY JET VENTILATION; (HFJV); and high-frequency oscillation (HFO).
MSH

use this term only for respiratory therapy; do not confuse with HYPERPNEA.
CSP

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vyšší nervová činnost

A term used in Eastern European research literature on brain and behavior physiology for cortical functions. It refers to the highest level of integrative function of the brain, centered in the CEREBRAL CORTEX, regulating language, thought, and behavior via sensory, motor, and cognitive processes.
MSH

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hinduismus

A complex body of social, cultural, and religious beliefs and practices evolved in and largely confined to the Indian subcontinent and marked by a caste system, an outlook tending to view all forms and theories as aspects of one eternal being and truth, and the practice of the way of works, the way of knowledge, or the way of devotion as a means of release from the round of rebirths. (From Webster, 3d ed)
MSH

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spojovací oblasti – exony

Immunoglobulin heavy chain gene exons coding for the hinge region of the heavy chains between the first constant region (on the FAB FRAGMENTS) and the second constant region (on the FC FRAGMENTS).
MSH

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kyčel

The projecting part on each side of the body, formed by the side of the pelvis and the top portion of the femur.
MSH

projecting part on each side of the body, formed by the side of the pelvis and the top portion of the femur; includes the joint between the head of the femur and the acetabulum.
CSP

The lateral prominence of the pelvis from the waist to the thigh.
NCI

The lateral prominence of the pelvis from the waist to the thigh. (NCI)
NCI

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kyčel – kontraktura

Permanent fixation of the hip in primary positions, with limited passive or active motion at the hip joint. Locomotion is difficult and pain is sometimes present when the hip is in motion. It may be caused by trauma, infection, or poliomyelitis. (From Current Medical Information & Technology, 5th ed)
MSH

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kyčel – luxace

Displacement of the femur bone from its normal position at the HIP JOINT.
MSH

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kyčel – luxace kongenitální

Congenital dislocation of the hip generally includes subluxation of the femoral head, acetabular dysplasia, and complete dislocation of the femoral head from the true acetabulum. This condition occurs in approximately 1 in 1000 live births and is more common in females than in males.
MSH

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kyčel – dysplazie u psů

A hereditary disease of the hip joints in dogs. Signs of the disease may be evident any time after 4 weeks of age.
MSH

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kyčel – fraktury

Fractures of the FEMUR HEAD; the FEMUR NECK; (FEMORAL NECK FRACTURES); the trochanters; or the inter- or subtrochanteric region. Excludes fractures of the acetabulum and fractures of the femoral shaft below the subtrochanteric region (FEMORAL FRACTURES).
MSH

breaks or rupture in bones or cartilages of the hip; for fractures of the femoral shaft below the subtrochanteric region use LIMB FRACTURE.
CSP

A finding of traumatic injury to the hip in which the continuity of either the femoral head, femoral neck, intertrochanteric or subtrochanteric regions is broken.
NCI

Traumatic or pathological injury to the hip in which the continuity of either the femoral head, femoral neck, intertrochanteric or subtrochanteric regions is broken. Symptoms include pain in the hip or groin, bruising and swelling in and around the hip area. The injured hip is turned outward and the leg appears shorter on that side.
NCI

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kyčelní kloub

A ball-and-socket joint between the head of the femur and the acetabulum. (NCI)
NCI

A ball-and-socket joint between the head of the femur and the acetabulum.
NCI

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kyčel – protézy

Replacement for a hip joint.
MSH

artificial substitute, constructed of either synthetic or biological material, which is used to partially or totally replace or repair injured or diseased hips.
CSP

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