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imunoglobulin G

major immunoglobulin in normal human serum, distributed evenly between the intravascular and extravascular pools; it is the major antibody of secondary immune responses and the exclusive antitoxin class.
CSP

The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B.
MSH

An immunoglobulin isotype (subclass) that characterizes secondary immune responses. This isotype is further broken down into several smaller subclasses (IgG1, IgG2a, IgG2b, IgG3 in the mouse; IgG1-4 in the human), and each subclass is differentially synthesized and secreted into the serum upon differential immune stimuli.
NCI

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Immunoglobulin IgG4

A subtype of IgG that makes up a minor part of circulating antibodies in healthy individuals. It is elevated in various diseases and infections.
NCI

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imunoglobulin M

pentameric immunoglobulin largely confined to the intravascular pool and the predominant early antibody frequently seen in the immune response to antigenically complex infectious organisms.
CSP

A class of immunoglobulin bearing mu chains (IMMUNOGLOBULIN MU-CHAINS). IgM can fix COMPLEMENT. The name comes from its high molecular weight and originally being called a macroglobulin.
MSH

The major immunoglobulin secreted during a primary immune response. IgM binds with low affinity but high avidity (multiple binding sites) because it not only occurs as monomers but also as pentamers and hexamers.
NCI

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leguáni

Large herbivorous tropical American lizards.
MSH

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ileum – nemoci

Pathological development in the ILEUM including the ILEOCECAL VALVE.
MSH

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ileum – nádory

Tumors or cancer in the ILEUM region of the small intestine (INTESTINE, SMALL).
MSH

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ileitida

Inflammation of any segment of the ILEUM and the ILEOCECAL VALVE.
MSH

Inflammation of the ileum.
NCI

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ileocekální chlopeň

The valve, at the junction of the CECUM with the COLON, that guards the opening where the ILEUM enters the LARGE INTESTINE.
MSH

The valve between the ileum of the small intestine and the cecum of the large intestine.
NCI

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ileostomie

Surgical creation of an external opening into the ILEUM for fecal diversion or drainage. This replacement for the RECTUM is usually created in patients with severe INFLAMMATORY BOWEL DISEASES. Loop (continent) or tube (incontinent) procedures are most often employed.
MSH

An opening into the ileum, part of the small intestine, from the outside of the body. An ileostomy provides a new path for waste material to leave the body after part of the intestine has been removed.
NCI

a surgery that makes an opening into the ileum (part of the small bowel)
CHV

Surgical creation of an external opening into the ileum for fecal diversion or drainage. Loop or tube procedures are most often employed. (MeSH)
NCI

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ileum

The distal and narrowest portion of the SMALL INTESTINE, between the JEJUNUM and the ILEOCECAL VALVE of the LARGE INTESTINE.
MSH

distal part of the small intestine, extending from the jejunum to the cecum.
CSP

The final section of the small intestine. (NCI)
NCI

The final section of the small intestine.
NCI

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arteria iliaca

Either of two large arteries originating from the abdominal aorta; they supply blood to the pelvis, abdominal wall and legs.
MSH

A branch of the abdominal aorta that supplies blood to the lower trunk and the legs.
NCI

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vena iliaca

A vein on either side of the body which is formed by the union of the external and internal iliac veins and passes upward to join with its fellow of the opposite side to form the inferior vena cava.
MSH

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os ilium

The broad, dorsal, upper, and widest of the three principal bones composing either half of the pelvis. (NCI)
NCI

The uppermost and widest part of the hip bone
CHV

The broad, dorsal, upper, and widest of the three principal bones composing either half of the pelvis.
NCI

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nelegitimnost

The state of birth outside of wedlock. It may refer to the offspring or the parents.
MSH

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Illinois

A state in the central midwest United States. Its capital is Springfield.
NCI

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Nevzdělanost

Not able to read or write.
NCI

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iluze

The misinterpretation of a real external, sensory experience.
MSH

misinterpretation of a real external, sensory experience.
CSP

A misperception of a real external stimulus.
NCI

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obraz – zesílení

Improvement of the quality of a picture by various techniques, including computer processing, digital filtering, echocardiographic techniques, light and ultrastructural MICROSCOPY, fluorescence spectrometry and microscopy, scintigraphy, and in vitro image processing at the molecular level.
MSH

improvement of the quality of a picture or image by various techniques; may include improvements to the equipment producing the images.
CSP

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obraz – interpretace počítačová

Methods developed to aid in the interpretation of ultrasound, radiographic images, etc., for diagnosis of disease.
MSH

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obrazy – zpracování pomocí počítače

A technique of inputting two-dimensional images into a computer and then enhancing or analyzing the imagery into a form that is more useful to the human observer.
MSH

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Reconstructie van een beeld

The process of generating an image from the raw data, or set of unprocessed measurements, made by an imaging system. (from AmershamHealth Medcyclopaedia)
NCI

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imaginace

A new pattern of perceptual or ideational material derived from past experience.
MSH

new pattern of perceptual or ideational material derived from past experience; formation of a mental image of something that is neither perceived as real nor present to the senses.
CSP

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imidazoly

Compounds containing 1,3-diazole, a five membered aromatic ring containing two nitrogen atoms separated by one of the carbons. Chemically reduced ones include IMIDAZOLINES and IMIDAZOLIDINES. Distinguish from 1,2-diazole (PYRAZOLES).
MSH

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imidy

compound containing the bivalent group NH, to which only acid radicals are attached.
CSP

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imidokarb

One of ANTIPROTOZOAL AGENTS used especially against BABESIA in livestock. Toxicity has been reported.
MSH

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imidoestery

Esters of the hypothetical imidic acids. They react with amines or amino acids to form amidines and are therefore used to modify protein structures and as cross-linking agents.
MSH

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iminy

molecule containing a nitrogen atom attached to a carbon atom by a double bond; the nitrogen is also covalently linked to a hydrogen.
CSP

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iminokyseliny

zwitterionic compounds containing COO- and C=NHH+ groups.
CSP

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imipenem

Semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. It is stable to beta-lactamases. Clinical studies have demonstrated high efficacy in the treatment of infections of various body systems. Its effectiveness is enhanced when it is administered in combination with CILASTATIN, a renal dipeptidase inhibitor.
MSH

An antibiotic drug used to treat severe or very resistant infection. It belongs to the family of drugs called carbapenems.
NCI

A broad-spectrum, semi-synthetic beta-lactam carbapenem derived from thienamycin, produced by Streptomyces cattleya. Imipenem binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes that are involved in the last stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. This inactivation results in the weakening of the bacterial cell wall and eventually causes cell lysis. Imipenem has the greatest affinity for PBP 1A, 1B, and 2, and its lethal effect is related to binding to PBP 2 and 1B. This antibiotic is active against a wide range of gram-positive and gram-negative organisms and is stable in the presence of beta-lactamases. Check for “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=42116&idtype=1″ active clinical trials or “http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=42116&idtype=1&closed=1″ closed clinical trials using this agent. (“http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C570″ NCI Thesaurus)
PDQ

A broad-spectrum, semi-synthetic beta-lactam carbapenem derived from thienamycin, produced by Streptomyces cattleya. Imipenem binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes that are involved in the last stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. This inactivation results in the weakening of the bacterial cell wall and eventually causes cell lysis. Imipenem has the greatest affinity for PBP 1A, 1B, and 2, and its lethal effect is related to binding to PBP 2 and 1B. This antibiotic is active against a wide range of gram-positive and gram-negative organisms and is stable in the presence of beta-lactamases. (NCI05)
NCI

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imipramin

The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
MSH

dibenzazepine tricyclic antidepressant.
CSP

A synthetic tricyclic derivative, antidepressant Imipramine enhances monoamine neurotransmission in certain areas of the brain. It also induces sedation through histamine 1 receptor blockage; hypotension through beta-adrenergic blockage; and diverse parasympatholytic effects. Imipramine has less sedative effect than other members of its therapeutic family. It is used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. (NCI04)
NCI

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